SEC Form 4 insider transactions

Large owner Oasis Management Co Ltd. sold $313,792 worth of shares (10,493 units at $29.90) (SEC Form 4)

Chief Strategy Officer Langlais Kerri M. converted options into 327,054 shares and returned 180,860 shares to the company, increasing direct ownership by 4% to 3,864,493 units (SEC Form 4)

Chief Executive Officer Prager Paul B. converted options into 981,162 shares and returned 542,582 shares to the company, increasing direct ownership by 66% to 1,101,020 units (SEC Form 4)

Chief Financial Officer Fleury Patrick returned 128,695 shares to the company and converted options into 327,054 shares, increasing direct ownership by 6% to 3,608,801 units (SEC Form 4)

Chief Technology Officer Khan Nazar M. converted options into 817,635 shares and sold 452,152 shares, increasing direct ownership by 98% to 738,626 units (SEC Form 4)

Chief Financial Officer Prentiss Christopher B covered exercise/tax liability with 12,267 shares, decreasing direct ownership by 3% to 338,924 units (SEC Form 4) to satisfy tax liability

Chief Commercial Officer Grow Brian exercised 958 shares at a strike of $1.24, increasing direct ownership by 0.11% to 900,682 units (SEC Form 4)

SEC Form 4 filed by Chief Accounting Officer Abrahamsen Danielle Nicole

SEC Form 4 filed by President & CEO Mirchandani Sanjay

SEC Form 4 filed by Chief Financial Officer Merrill Gary

Director Kaushal Nitin was granted 306,433 shares (SEC Form 4)

General Counsel & Secretary Riley Christopher sold $16,218 worth of shares (8,916 units at $1.82), decreasing direct ownership by 0.47% to 1,870,249 units (SEC Form 4) (withholding obligation)

CEO & President Kohn Bernhard L Iii sold $33,785 worth of shares (18,502 units at $1.83), decreasing direct ownership by 0.30% to 6,245,045 units (SEC Form 4) (for tax liability)

Chief Financial Officer Cross Shawn exercised 12,941 shares at a strike of $16.45 and sold $325,596 worth of shares (12,941 units at $25.16) as part of a pre-agreed trading plan (SEC Form 4)

Chief Legal & Compliance Ofc Ledesma Bruce was granted 76,220 shares and disposed of $3,168,141 worth of shares (26,129 units at $121.25) as part of a pre-agreed trading plan, increasing direct ownership by 26% to 245,880 units (SEC Form 4) (withholding tax)

Chief Accounting Officer Bennett David P disposed of $3,960,752 worth of shares (32,666 units at $121.25) as part of a pre-agreed trading plan and was granted 95,274 shares, increasing direct ownership by 48% to 193,575 units (SEC Form 4) (tax withholding)

Chief Operating Officer Miller Nicholas Marco was granted 57,165 shares and disposed of $2,377,228 worth of shares (19,606 units at $121.25) as part of a pre-agreed trading plan, increasing direct ownership by 22% to 206,613 units (SEC Form 4) to satisfy withholding obligation

President Wenger Howard was granted 114,330 shares and disposed of $4,751,666 worth of shares (39,189 units at $121.25) as part of a pre-agreed trading plan, increasing direct ownership by 18% to 484,180 units (SEC Form 4) (tax withholding)

Director Sasse Benjamin E was granted 2,393 shares, increasing direct ownership by 89% to 5,084 units (SEC Form 4)

Director Waite G Thomas Iii was granted 1,436 shares, increasing direct ownership by 9% to 17,362 units (SEC Form 4)

Director Cappelli Gregory William was granted 1,436 shares, increasing direct ownership by 96% to 2,934 units (SEC Form 4)

Director Mcrobbie Michael A. was granted 1,436 shares, increasing direct ownership by 19% to 9,069 units (SEC Form 4)

Director Grusky Robert R was granted 1,436 shares, increasing direct ownership by 14% to 11,382 units (SEC Form 4)

Director Slocum William J was granted 1,436 shares, increasing direct ownership by 23% to 7,815 units (SEC Form 4)

Director Dinh Viet D was granted 2,393 shares, increasing direct ownership by 11% to 24,910 units (SEC Form 4)

Director Beason Charlotte F was granted 1,436 shares, increasing direct ownership by 6% to 24,093 units (SEC Form 4)

Director Brogley Rita D was granted 1,436 shares, increasing direct ownership by 11% to 14,110 units (SEC Form 4)

Large owner Magnetar Financial Llc sold $331,181 worth of shares (2,770 units at $119.56) (SEC Form 4)

Chief Executive Officer Shugar Daniel S was granted 214,368 shares and disposed of $8,909,086 worth of shares (73,477 units at $121.25) as part of a pre-agreed trading plan, increasing direct ownership by 19% to 887,230 units (SEC Form 4) (tax withholding)

Large owner Magnetar Financial Llc sold $36,192,674 worth of shares (296,160 units at $122.21) (SEC Form 4)

SEC Form 4 filed by Large owner Magnetar Financial Llc

Large owner Magnetar Financial Llc sold $75,807,036 worth of shares (620,672 units at $122.14) (SEC Form 4)

Large owner Magnetar Financial Llc sold $104,716,272 worth of shares (857,367 units at $122.14) (SEC Form 4)

Large owner Magnetar Financial Llc sold $117,394,342 worth of shares (961,169 units at $122.14) (SEC Form 4)

SEC Form 4 filed by Director Kim Vyacheslav

Large owner Isq Global Fund Ii Gp Llc sold $7,714,019 worth of shares (160,200 units at $48.15) (SEC Form 4)

SEC Form 4 filed by SVP/Risk Officer Belton Curtis

Portfolio Manager Lind Joseph exercised 12,833 in-the-money shares at a strike of $6.50, increasing direct ownership by 39% to 45,333 units (SEC Form 4)

President Farahi Bob exercised 66,667 shares at a strike of $116.65 and covered exercise/tax liability with 51,175 shares, increasing direct ownership by 9% to 197,178 units (SEC Form 4)

Officer Patel Rahul G. sold $205,290 worth of Common Stock (2,281 units at $90.00) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 111,320 units (SEC Form 4)

SEC Form 4 filed by Chief Operating Officer Bansi Pankaj

Chief Legal Officer & EVP Muchmore James J covered exercise/tax liability with 27,708 shares, decreasing direct ownership by 3% to 764,800 units (SEC Form 4)

CEO & President Davis Samuel Carl covered exercise/tax liability with 21,114 shares, decreasing direct ownership by 5% to 425,566 units (SEC Form 4)

Director Maerker Salmon Denise exercised 565,084 in-the-money units of CPOs at a strike of $0.09 and sold $327,749 worth of CPOs (565,084 units at $0.58) (SEC Form 4)

SEC Form 4 filed by CEO Chambriard Magda Maria De Regina

SEC Form 4 filed by Chief Product Officer Da Silva William Franca

SEC Form 4 filed by Former officer Parkinson Christopher Iain

SEC Form 4 filed by Chief Financial Officer Melgarejo Fernando Sabbi

SEC Form 4 filed by Chief Engineering Officer Lopes Renata Faria Rodrigues Baruzzi

Chief Financial Officer Apel Daniel Joseph sold $934,285 worth of shares (13,095 units at $71.35) as part of a pre-agreed trading plan, decreasing direct ownership by 7% to 162,905 units (SEC Form 4) (withholding obligation)

SEC Form 4 filed by Chief Upstream Officer Dos Anjos Sylvia Maria Couto

SEC Form 4 filed by Chief Corp. Affairs Coppetti Clarice

Chief Medical Officer Hamilton James C sold $750,000 worth of shares (10,000 units at $75.00) as part of a pre-agreed trading plan, decreasing direct ownership by 4% to 226,958 units (SEC Form 4)

Amendment: Officer Macdonald Andrew covered exercise/tax liability with 634 shares, decreasing direct ownership by 0.19% to 338,387 units (SEC Form 4)

CEO and Chairperson Ullal Jayshree sold $75,944,314 worth of shares (428,000 units at $177.44) as part of a pre-agreed trading plan (SEC Form 4)

President and COO Rubinstein Julie exercised 44,166 shares at a strike of $8.46 and sold $798,423 worth of shares (57,180 units at $13.96) as part of a pre-agreed trading plan, decreasing direct ownership by 3% to 382,132 units (SEC Form 4)

Executive Vice President & CFO Samad Sam was granted 108 shares, increasing direct ownership by 0.32% to 33,376 units (SEC Form 4)

SVP for Diagnostic Services Plewman Patrick increased direct ownership by 0.32% to 15,247 units (SEC Form 4)

Director Gregg Vicky B was granted 68 shares, increasing direct ownership by 0.40% to 17,172 units (SEC Form 4)

Director Carter Robert B increased direct ownership by 0.26% to 2,711 units (SEC Form 4)