AN2 Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing treatments for rare, chronic, and serious infectious diseases. It is developing epetraborole, a once-daily oral treatment for patients with chronic non-tuberculous mycobacterial lung disease. The company was incorporated in 2017 and is headquartered in Menlo Park, California.
IPO Year: 2022
Exchange: NASDAQ
Website: https://www.an2therapeutics.com
| Date | Price Target | Rating | Analyst |
|---|---|---|---|
| 8/9/2024 | In-line → Underperform | Evercore ISI | |
| 8/9/2024 | $5.00 → $1.00 | Outperform → Market Perform | Leerink Partners |
| 7/3/2024 | $5.00 | Market Perform → Outperform | Leerink Partners |
| 4/2/2024 | $6.00 | Mkt Perform → Mkt Outperform | JMP Securities |
| 2/13/2024 | $23.00 → $7.00 | Outperform → Market Perform | Leerink Partners |
| 2/12/2024 | $25.00 → $7.00 | Outperform → In-line | Evercore ISI |
| 2/12/2024 | Outperform → Perform | Oppenheimer | |
| 2/12/2024 | Mkt Outperform → Mkt Perform | JMP Securities | |
| 1/4/2024 | $30.00 | Mkt Outperform | JMP Securities |
| 7/18/2022 | $22.00 | Outperform | Oppenheimer |
8-K - AN2 Therapeutics, Inc. (0001880438) (Filer)
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8-K - AN2 Therapeutics, Inc. (0001880438) (Filer)
SCHEDULE 13D/A - AN2 Therapeutics, Inc. (0001880438) (Subject)
8-K - AN2 Therapeutics, Inc. (0001880438) (Filer)
10-Q - AN2 Therapeutics, Inc. (0001880438) (Filer)
8-K - AN2 Therapeutics, Inc. (0001880438) (Filer)
SCHEDULE 13D - AN2 Therapeutics, Inc. (0001880438) (Subject)
8-K - AN2 Therapeutics, Inc. (0001880438) (Filer)
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4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
4 - AN2 Therapeutics, Inc. (0001880438) (Issuer)
Study highlights high mortality despite standard of care and provides critical data to optimize design for upcoming proof-of-concept trial for epetraborole Observational Study funded by the National Institutes of Health AN2 Therapeutics, Inc. (NASDAQ:ANTX), a clinical-stage biopharmaceutical company developing novel small molecule therapeutics derived from its boron chemistry platform, today announced the completion of a 200-patient observational study in acute melioidosis, a highly lethal bacterial infection and recognized biothreat. The study, conducted under real-world conditions in acute hospital settings, evaluated patients receiving the current standard of care (SoC): IV meropenem
Epetraborole's potent activity against M. abscessus supports further investigation as a potential therapy for disease with an estimated all-cause mortality of 45% AN2 Therapeutics, Inc. (NASDAQ:ANTX), a biopharmaceutical company focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform, today announced that the company will present a poster highlighting the preclinical activity of epetraborole against M. abscessus on Thursday, May 29, 2025 at the Nontuberculous Mycobacteria Conference to be held May 27-30, 2025 at Colorado State University. It is estimated that M. abscessus affects approximately 50,000 patients in the U.S., Japan and
EBO-301 truncated Phase 3 study (n=97) misses primary endpoint; results unable to confirm clinical efficacy observed in Phase 2 study, patients had underlying severe, advanced MAC lung disease Extensive enabling NTM data provides potential path forward in M. abscessus lung disease Company focus remains centered on boron chemistry pipeline with initiation of high impact clinical programs in infectious diseases and an emerging oncology portfolio Initiated start up activities for Phase 1 first in human study in healthy volunteers of AN2-502998, under development to treat chronic Chagas disease Topline data for standard-of-care melioidosis observational trial expected in 2Q25; Phase 2 study
AN2 Therapeutics, Inc. (NASDAQ:ANTX), a biopharmaceutical company focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform, today announced that Eric Easom, Co-Founder, Chairman, President and CEO will participate in a fireside chat at the 2025 Citizens JMP Life Sciences Conference being held from May 7-8, 2025 in New York. Details of the event is as follows: Citizens JMP Life Sciences Conference Eric Easom, Co-Founder, Chairman, President and CEO will participate in a fireside chat on Wednesday, May 7, 2025 at 9:00 am ET, and members of management will be available for 1X1 meetings. A webcast can be accessed on the Investors se
Phase 3 topline data expected 2Q25 for epetraborole in patients with treatment-refractory MAC lung disease (TR MAC) Phase 1 first in human study of AN2-502998, under development for Chagas disease, to start mid-2025 in healthy volunteers Topline data for melioidosis observational trial expected in 2Q25; Phase 2 epetraborole study planned for 2H25 First oncology candidate(s) from boron chemistry platform on track to advance into development in 2H25 Cash, cash equivalents, and investments of $88.6 million at December 31, 2024 anticipated to fund operations through 2027 under current strategic plan AN2 Therapeutics, Inc. (NASDAQ:ANTX), a biopharmaceutical company focused on discovering an
AN2 Therapeutics, Inc. (NASDAQ:ANTX), a biopharmaceutical company focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform, today announced that Eric Easom, Co-Founder, Chairman, President and CEO, will present at the Leerink Partners Global Healthcare Conference. Details of the event are as follows: Leerink Partners Global Healthcare Conference Eric Easom, Co-Founder, Chairman, President and CEO, will provide a corporate overview on Wednesday, March 12, 2025 at 2:20 pm ET, and members of management will be available for 1X1 meetings. A webcast of the presentation can be accessed on the Investors section of the AN2 Therapeutic
AN2 Selects QOL-B as New Phase 3 Primary Efficacy Endpoint Goal to Accelerate Unblinding Phase 3 Data in Q2 2025 Ahead of Potential FDA Meeting AN2 Therapeutics, Inc. (NASDAQ:ANTX), a biopharmaceutical company focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform, today announced its submission of an amended statistical analysis plan to the FDA selecting the Quality of Life – Bronchiectasis (QOL-B) respiratory domain patient reported outcome (PRO) instrument as the primary efficacy endpoint for the Phase 3 part of the EBO-301 trial. The Company will evaluate whether the Phase 3 data supports the Phase 2 findings, where potentia
AN2 Therapeutics, Inc. (NASDAQ:ANTX), a biopharmaceutical company focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform, today announced that company management will participate in two upcoming investor conferences in March. Details of the events are as follows: TD Cowen 45th Annual Health Care Conference Eric Easom, Co-Founder, Chairman, President and CEO will provide a corporate overview on Monday, March 3, 2025 at 2:30 pm ET, and members of management will be available for 1X1 meetings. Leerink Partners Global Healthcare Conference Members of management will be available for 1X1 meetings on Wednesday, March 12, 2025. A
AN2 Therapeutics, Inc. (NASDAQ:ANTX), a biopharmaceutical company focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform, today announced that Eric Easom, Co-Founder, Chairman, President and CEO, will present at the Oppenheimer 35th Annual Healthcare Life Sciences Conference. Details of the event are as follows: Oppenheimer 35th Annual Healthcare Life Sciences Conference (virtual) Eric Easom, Co-Founder, Chairman, President and CEO will provide a corporate overview on Wednesday, February 12, 2025 at 3:20pm ET. A webcast of the presentation can be accessed on the Investors section of the AN2 Therapeutics website at www.an2t
AN2 Therapeutics, Inc. (NASDAQ:ANTX), a biopharmaceutical company focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform, today announced that company management will participate in two upcoming investor conferences in December. Details of the events are as follows: 7th Annual Evercore HealthCONx Conference, December 3-5, 2024 Eric Easom, Co-Founder, Chairman, President and CEO, will provide a corporate overview on Wednesday, December 4 at 8:20am ET Oppenheimer's Movers in Rare Disease Summit, December 12, 2024 Members of management will be available for 1X1 meetings on Thursday, December 12, 2024 A webcast of the Ev
Evercore ISI downgraded AN2 Therapeutics from In-line to Underperform
Leerink Partners downgraded AN2 Therapeutics from Outperform to Market Perform and set a new price target of $1.00 from $5.00 previously
Leerink Partners upgraded AN2 Therapeutics from Market Perform to Outperform and set a new price target of $5.00
JMP Securities upgraded AN2 Therapeutics from Mkt Perform to Mkt Outperform and set a new price target of $6.00
Leerink Partners downgraded AN2 Therapeutics from Outperform to Market Perform and set a new price target of $7.00 from $23.00 previously
Evercore ISI downgraded AN2 Therapeutics from Outperform to In-line and set a new price target of $7.00 from $25.00 previously
Oppenheimer downgraded AN2 Therapeutics from Outperform to Perform
JMP Securities downgraded AN2 Therapeutics from Mkt Outperform to Mkt Perform
JMP Securities initiated coverage of AN2 Therapeutics with a rating of Mkt Outperform and set a new price target of $30.00
Oppenheimer resumed coverage of AN2 Therapeutics with a rating of Outperform and set a new price target of $22.00
Company extends BRII-179 license to global rights and introduces preventive vaccine, PreHevbri® in Greater China and Asia Pacific markets New data from BRII-835 + PEG-IFN-α study have demonstrated that robust anti-HBs antibody responses at the end of treatment are associated with sustained HBsAg loss 24 weeks post treatment Company owns exclusive global rights of BRII-693 in development for difficult-to-treat carbapenem-resistant Gram-negative bacterial infections Dr. David Margolis appointed as Chief Medical Officer to lead organization's late-stage clinical programs towards commercialization DURHAM, N.C. and BEIJING, July 5, 2023 /PRNewswire/ -- Brii Biosciences Limited ("Brii Bio" or the
AN2 Therapeutics, Inc., (NASDAQ:ANTX) a clinical-stage biopharmaceutical company developing treatments for rare, chronic, and serious infectious diseases with high unmet needs, today announced the appointment of Maggie FitzPatrick to its Board of Directors. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220509005229/en/Maggie FitzPatrick, Board of Directors, AN2 Therapeutics, Inc. (Photo: Business Wire) Maggie FitzPatrick is a highly accomplished corporate affairs executive who has led global communications and public affairs at leading healthcare companies, including Johnson & Johnson and Cigna. "As a recognized leader in the a
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AN2 Therapeutics, Inc. (NASDAQ:ANTX), a biopharmaceutical company focused on discovering and developing novel small molecule therapeutics derived from its boron chemistry platform, today announced that it has adopted a limited duration stockholder rights plan, which is scheduled to expire on August 15, 2025. The Company recently became aware of the rapid accumulation of a significant amount (19.3%) of the common stock of the Company by BML Investment Partners, L.P. (BML), as disclosed in a Schedule 13G/A filed with the U.S. Securities and Exchange Commission (SEC) on August 14, 2024. The Board of Directors believes that the rights plan will help promote the fair and equal treatment of all
Phase 2/3 trial (EBO-301) in treatment-refractory Mycobacterium avium Complex (TR-MAC) continues with Phase 2 topline results expected in summer 2024 and Phase 3 enrollment pause in place during continued analysis of incoming data; plan to discuss with FDA Cash, cash equivalents, and investments of $134.5 million at December 31, 2023 AN2 Therapeutics, Inc. (NASDAQ:ANTX), a clinical-stage biopharmaceutical company focused on developing treatments for rare, chronic, and serious infectious diseases with high unmet needs, today reported financial results for the fourth quarter and year ended December 31, 2023. "AN2's cash position remains strong as we advance our innovative boron-based pi
Transitioning HBV cure programs into multiple late-stage combination studies with interim results throughout 2024 and 2025 informing Company's registrational strategy Integrating R&D, manufacturing and commercial upsides by acquiring full intellectual property rights of BRII-179 and expanding its manufacturing footprint Prioritizing company resources with a robust cash balance of US$376 million supporting operations until 2027 Company to host a conference call (English session) on March 25 at 8:30 AM ET / 8:30 PM HKT DURHAM, N.C. and BEIJING, March 22, 2024 /PRNewswire/ -- Brii Biosciences Limited ("Brii Bio" or the "Company", stock code: 2137.HK), a biotechnology company developing therapie
Enrollment well underway in Phase 3 part of pivotal Phase 2/3 study of epetraborole in treatment-refractory Mycobacterium avium complex (MAC) lung disease On track to announce Phase 2 clinical data summer 2024 Cash and investments of $150.2 million at September 30, 2023; cash runway anticipated to fund operations through summer 2025 AN2 Therapeutics, Inc. (NASDAQ:ANTX), a clinical-stage biopharmaceutical company focused on developing treatments for rare, chronic, and serious infectious diseases with high unmet needs, today reported financial results for the quarter ended September 30, 2023. "We are incredibly proud of the significant milestones achieved recently and over the p
Sufficient patients in screening expected to complete enrollment in Phase 2 portion of pivotal Phase 2/3 study of epetraborole in treatment-refractory Mycobacterium avium complex (MAC) lung disease Expected initiation of Phase 3 portion of pivotal Phase 2/3 study in September AN2 Therapeutics, Inc. (NASDAQ:ANTX), a clinical-stage biopharmaceutical company focused on developing treatments for rare, chronic, and serious infectious diseases with high unmet needs, today reported financial results for the quarter ended June 30, 2023. "We're pleased with the accelerated pace of enrollment in our pivotal Phase 2/3 study evaluating epetraborole for treatment-refractory MAC lung disease and be
Nearly 80 clinical sites active in pivotal Phase 2/3 trial of epetraborole in treatment-refractory Mycobacterium avium complex (MAC) lung disease AN2 Therapeutics, Inc. (NASDAQ:ANTX), a clinical-stage biopharmaceutical company focused on developing treatments for rare, chronic, and serious infectious diseases with high unmet needs, today reported financial results for the quarter ended March 31, 2023. "In the first quarter we continued to advance our pivotal Phase 2/3 trial evaluating epetraborole for treatment-refractory MAC lung disease with a total of nearly 80 clinical sites active worldwide. We are pleased with the momentum we're seeing in the Asia-Pacific region, particularly at
Approaching 60 clinical sites participating in pivotal Phase 2/3 trial of epetraborole in treatment-refractory Mycobacterium avium complex (MAC) lung disease to date Opened up sites in three additional countries -- Japan, South Korea, and Australia in addition to the U.S.; Japan has some of the highest rates of MAC lung disease in the world Activities underway to advance development of epetraborole for acute systemic melioidosis using non-dilutive funding AN2 Therapeutics, Inc. (NASDAQ:ANTX), a clinical-stage biopharmaceutical company focused on developing treatments for rare, chronic, and serious infectious diseases with high unmet needs, today reported financial results for the fou
Company maintains priority focus on clinical programs to develop a novel functional cure for hepatitis B viral (HBV) infection and a potential first-of-its-kind treatment for postpartum depression (PPD) and major depressive disorders (MDD) Multiple Phase 2a proof-of-concept (POC) clinical data readouts and Phase 2b clinical trial initiations expected in 2023 Operations well-funded through 2025 Company to host conference call today at 8:00 PM HKT / 8:00 AM ET DURHAM, N.C. and BEIJING, March 24, 2023 /PRNewswire/ -- Brii Biosciences Limited ("Brii Bio," "we," or the "Company", stock code: 2137.HK), a biotechnology company developing therapies to improve patient health and choice across disease