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Compare · ACRS vs ATHE

ACRS vs ATHE

Side-by-side comparison of Aclaris Therapeutics Inc. (ACRS) and Alterity Therapeutics Limited (ATHE): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both ACRS and ATHE operate in Biotechnology: Pharmaceutical Preparations (Health Care), so they compete in similar markets.
  • ACRS is the larger of the two at $608.9M, about 10.1x ATHE ($60.2M).
  • Over the past year, ACRS is up 194.3% and ATHE is down 18.2% - ACRS leads by 212.5 points.
  • ACRS has been more active in the news (8 items in the past 4 weeks vs 6 for ATHE).
  • ACRS has more recent analyst coverage (18 ratings vs 3 for ATHE).
PerformanceACRS+194.28%ATHE-18.20%
2025-06-09+0.00%2026-06-08
MetricACRSATHE
Company
Aclaris Therapeutics Inc.
Alterity Therapeutics Limited
Price
$4.37+0.00%
$3.91-2.49%
Market cap
$608.9M
$60.2M
1M return
-10.27%
-15.73%
1Y return
+194.28%
-18.20%
Industry
Biotechnology: Pharmaceutical Preparations
Biotechnology: Pharmaceutical Preparations
Exchange
NASDAQ
NASDAQ
IPO
2015
News (4w)
8
6
Recent ratings
18
3
ACRS

Aclaris Therapeutics Inc.

Aclaris Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing a pipeline of novel, small molecule therapeutics to address the needs of patients with immuno-inflammatory diseases. The company has a multi-stage portfolio of drug candidates powered by a research and development engine exploring protein kinase regulation. Its products pipeline includes ATI-450, an investigational oral, novel, small molecule selective MK2 inhibitor compound, which is being developed as a treatment for moderate to severe rheumatoid arthritis and additional immuno-inflammatory diseases; ATI-1777, an investigational topical soft JAK 1/3 inhibitor compound, which is being developed as a treatment for moderate to severe atopic dermatitis; and ATI-2138, an investigational oral ITK/TXK/JAK3 inhibitor compound, which is being developed as a treatment for psoriasis and/or inflammatory bowel disease. It also provides contract research services. The company was incorporated in 2012 and is headquartered in Wayne, Pennsylvania.

ATHE

Alterity Therapeutics Limited

Alterity Therapeutics Limited researches and develops therapeutic drugs for the treatment of Parkinsonian's disease and other neurodegenerative diseases in Australia. The company's lead drug candidates is ATH434 that has completed Phase I clinical trial for the treatment of Parkinson's disease. It is also developing PBT2 for used as an antimicrobial agent. The company was formerly known as Prana Biotechnology Limited and changed its name to Alterity Therapeutics Limited in April 2019. The company was founded in 1997 and is based in Melbourne, Australia.

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