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Compare · AMGN vs PRME

AMGN vs PRME

Side-by-side comparison of Amgen Inc. (AMGN) and Prime Medicine Inc. (PRME): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both AMGN and PRME operate in Biotechnology: Biological Products (No Diagnostic Substances) (Health Care), so they compete in similar markets.
  • AMGN is the larger of the two at $185.95B, about 278.3x PRME ($668.0M).
  • Over the past year, AMGN is up 21.6% and PRME is up 124.2% - PRME leads by 102.5 points.
  • AMGN has been more active in the news (9 items in the past 4 weeks vs 6 for PRME).
  • AMGN has more recent analyst coverage (25 ratings vs 15 for PRME).
PerformanceAMGN+21.63%PRME+124.17%
2025-04-28+0.00%2026-04-24
MetricAMGNPRME
Company
Amgen Inc.
Prime Medicine Inc.
Price
$344.50-1.18%
$3.71-3.89%
Market cap
$185.95B
$668.0M
1M return
-2.63%
+1.64%
1Y return
+21.63%
+124.17%
Industry
Biotechnology: Biological Products (No Diagnostic Substances)
Biotechnology: Biological Products (No Diagnostic Substances)
Exchange
NASDAQ
NASDAQ
IPO
1983
2022
News (4w)
9
6
Recent ratings
25
15
AMGN

Amgen Inc.

Amgen Inc. discovers, develops, manufactures, and delivers human therapeutics worldwide. It focuses on inflammation, oncology/hematology, bone health, cardiovascular disease, nephrology, and neuroscience areas. The company's products include Enbrel to treat plaque psoriasis, rheumatoid arthritis, and psoriatic arthritis; Neulasta that reduces the chance of infection due a low white blood cell count in patients cancer; Prolia to treat postmenopausal women with osteoporosis; Xgeva for skeletal-related events prevention; Otezla for the treatment of adult patients with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's disease; Aranesp to treat a lower-than-normal number of red blood cells and anemia; KYPROLIS to treat patients with relapsed or refractory multiple myeloma; and Repatha, which reduces the risks of myocardial infarction, stroke, and coronary revascularization. It also markets Nplate, Vectibix, MVASI, Parsabiv, EPOGEN, KANJINTI, BLINCYTO, Aimovig, EVENITY, AMGEVITATM, Sensipar/Mimpara, NEUPOGEN, IMLYGIC, Corlanor, and AVSOLA. Amgen Inc. serves healthcare providers, including physicians or their clinics, dialysis centers, hospitals, and pharmacies. It distributes its products through pharmaceutical wholesale distributors, as well as direct-to-consumer channels. The company has collaboration agreements with Novartis Pharma AG; UCB; Bayer HealthCare LLC; BeiGene, Ltd.; Eli Lilly and Company; Datos Health; and Verastem, Inc. to evaluate VS-6766 in combination with lumakrastm (Sotorasib) in patients with KRAS G12C-mutant non-small cell lung cancer. It has an agreement with Kyowa Kirin Co., Ltd. to jointly develop and commercialize KHK4083, a Phase 3-ready anti-OX40 fully human monoclonal antibody for the treatment of atopic dermatitis and other autoimmune diseases; and a strategic research and development collaboration with Neumora Therapeutics, Inc. Amgen Inc. was founded in 1980 and is headquartered in Thousand Oaks, California.