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Compare · LONA vs RVMD

LONA vs RVMD

Side-by-side comparison of LeonaBio Inc. (LONA) and Revolution Medicines Inc. (RVMD): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both LONA and RVMD operate in Biotechnology: Biological Products (No Diagnostic Substances) (Health Care), so they compete in similar markets.
  • RVMD is the larger of the two at $26.81B, about 342.7x LONA ($78.2M).
  • Over the past year, LONA is up 198.2% and RVMD is up 226.0% - RVMD leads by 27.8 points.
  • RVMD has been more active in the news (18 items in the past 4 weeks vs 14 for LONA).
  • RVMD has more recent analyst coverage (25 ratings vs 2 for LONA).
PerformanceLONA+198.21%RVMD+226.02%
2025-04-28+0.00%2026-04-24
MetricLONARVMD
Company
LeonaBio Inc.
Revolution Medicines Inc.
Price
$8.32-2.12%
$135.30+0.80%
Market cap
$78.2M
$26.81B
1M return
-10.25%
+43.55%
1Y return
+198.21%
+226.02%
Industry
Biotechnology: Biological Products (No Diagnostic Substances)
Biotechnology: Biological Products (No Diagnostic Substances)
Exchange
NASDAQ
NASDAQ
IPO
2020
2020
News (4w)
14
18
Recent ratings
2
25
RVMD

Revolution Medicines Inc.

Revolution Medicines, Inc., a clinical-stage precision oncology company, focuses on developing therapies to inhibit frontier targets in RAS-addicted cancers. The company is developing RMC-4630, an inhibitor of SHP2, which is in Phase 1/2 clinical trial for the treatment of solid tumors, such as gynecologic and colorectal cancer tumors. It also develops RMC-5845, a selective inhibitor of SOS1, a protein that converts RAS (OFF) to RAS (ON) in cells; and RMC-5552, a hyperactivated selective inhibitor of mTORC1 signaling in tumors. In addition, the company is developing RMC-6291, a mutant-selective inhibitor of KRASG12C(ON) and NRASG12C(ON); and RMC-6236, a RAS-selective inhibitor of multiple RAS(ON) variants. Further, it develops RAS(ON) Inhibitors targeting KRASG13C(ON) and KRASG12D(ON). Revolution Medicines, Inc. has a collaboration agreement with Sanofi for the research and development of SHP2 inhibitors, including RMC-4630. The company was incorporated in 2014 and is headquartered in Redwood City, California.

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