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Compare · LYRA vs MDLN

LYRA vs MDLN

Side-by-side comparison of Lyra Therapeutics Inc. (LYRA) and Medline Inc. (MDLN): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both LYRA and MDLN operate in Medical/Dental Instruments (Health Care), so they compete in similar markets.
  • MDLN is the larger of the two at $47.31B, about 1039.3x LYRA ($45.5M).
  • Over the past year, LYRA is down 96.8% and MDLN is down 11.6% - MDLN leads by 85.1 points.
  • MDLN has hit the wire 21 times in the past 4 weeks while LYRA has been quiet.
  • MDLN has more recent analyst coverage (25 ratings vs 7 for LYRA).
PerformanceLYRA-87.75%MDLN-11.64%
2025-12-17+0.00%2026-06-09
MetricLYRAMDLN
Company
Lyra Therapeutics Inc.
Medline Inc.
Price
$0.49-61.33%
$36.01+6.54%
Market cap
$45.5M
$47.31B
1M return
+0.00%
-8.80%
1Y return
-96.79%
-11.64%
Industry
Medical/Dental Instruments
Medical/Dental Instruments
Exchange
NASDAQ
NASDAQ
IPO
2020
2025
News (4w)
0
21
Recent ratings
7
25
LYRA

Lyra Therapeutics Inc.

Lyra Therapeutics, Inc., a clinical-stage therapeutics company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. The company's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. Its product candidates include LYR-210, an anti-inflammatory implantable drug matrix for the treatment of chronic rhinosinusitis (CRS), which is in Phase II clinical trial; and LYR-220 for CRS patients with and without nasal polyps. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.

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