Compare · MNPR vs MRK
MNPR vs MRK
Side-by-side comparison of Monopar Therapeutics Inc. (MNPR) and Merck & Company Inc. (MRK): market cap, price performance, sector, and recent activity on the wire.
Summary
- Both MNPR and MRK operate in Biotechnology: Pharmaceutical Preparations (Health Care), so they compete in similar markets.
- MRK is the larger of the two at $277.18B, about 777.8x MNPR ($356.4M).
- MRK has been more active in the news (23 items in the past 4 weeks vs 4 for MNPR).
- MRK has more recent analyst coverage (25 ratings vs 14 for MNPR).
- Company
- Monopar Therapeutics Inc.
- Merck & Company Inc.
- Price
- -
- -
- Market cap
- $356.4M
- $277.18B
- 1M return
- -
- -
- 1Y return
- -
- -
- Industry
- Biotechnology: Pharmaceutical Preparations
- Biotechnology: Pharmaceutical Preparations
- Exchange
- NASDAQ
- NYSE
- IPO
- 2019
- News (4w)
- 4
- 23
- Recent ratings
- 14
- 25
Monopar Therapeutics Inc.
Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing proprietary therapeutics to enhance clinical outcomes for cancer patients in the United States. It is involved in developing Validive, a clonidine mucobuccal tablet that is in Phase 2b/3 clinical trial for the treatment of radiation induced severe oral mucositis in oropharyngeal cancer patients; Camsirubicin, a topoisomerase II-alpha targeted analog of doxorubicin engineered to retain anticancer activity and for minimizing toxic effects on the heart, which is in Phase 2 clinical trial; and MNPR-101, a humanized monoclonal antibody for the treatment of advanced cancers and severe COVID-19 that is in preclinical stage. The company has a collaboration Grupo Español de Investigación en Sarcomas for the development of camsirubicin in patients with advanced soft tissue sarcoma; and NorthStar Medical Radioisotopes, LLC to develop radio-immuno-therapeutics targeting severe COVID-19. It also has a collaboration agreement with the Cancer Science Institute of Singapore to evaluate the activity of MNPR-202 and related analogs in multiple types of cancer. Monopar Therapeutics Inc. was founded in 2014 and is headquartered in Wilmette, Illinois.
Merck & Company Inc.
Merck & Co., Inc. operates as a healthcare company worldwide. It operates through two segments, Pharmaceutical and Animal Health segments. The Pharmaceutical segment offers human health pharmaceutical products in the areas of oncology, hospital acute care, immunology, neuroscience, virology, cardiovascular, diabetes, and women's health, as well as vaccine products. The Animal Health segment provides discovers, develops, manufactures, and markets a range of veterinary pharmaceuticals, vaccines, and health management solutions and services, as well as a suite of digitally connected identification, traceability, and monitoring products. The company has collaborations with AstraZeneca PLC; Bayer AG; Eisai Co., Ltd.; and Ridgeback Biotherapeutics. It serves drug wholesalers and retailers, hospitals, and government agencies; managed health care providers, such as health maintenance organizations, pharmacy benefit managers, and other institutions; and physicians and physician distributors, veterinarians, and animal producers. The company has collaboration agreement with Gilead Sciences, Inc. to co-develop and co-commercialize long-acting investigational treatment combinations of Lenacapavir and Islatravir in HIV; Amathus Therapeutics to develop treatments for neurodegenerative diseases; and Linnaeus Therapeutics, Inc. to evaluate LNS8801 in combination with KEYTRUDA for patients with advanced cancer. It also has a collaboration with Biomed X Gmbh for building on ongoing research projects in the fields of oncology (DNA damage response and RNA splicing) and autoimmunity (intestinal epithelial barrier in autoimmune diseases); and a collaboration agreement with NGM Biopharmaceuticals, Inc. to focus primarily on the development of novel medicines for unmet patient needs in retinal and CVM diseases, including heart failure. Merck & Co., Inc. was founded in 1891 and is headquartered in Kenilworth, New Jersey.
Latest MNPR
- SEC Form DEFA14A filed by Monopar Therapeutics Inc.
- SEC Form DEF 14A filed by Monopar Therapeutics Inc.
- Monopar Therapeutics Inc. filed SEC Form 8-K: Regulation FD Disclosure, Financial Statements and Exhibits
- Monopar Presents Phase 3 Data Showing Greater Neurologic Benefit with ALXN1840 vs SoC in Wilson Disease Patients with Neurologic Symptoms at AAN 2026
- SEC Form 4 filed by Robinson Chandler
- SEC Form 4 filed by Cittadine Andrew
- Amendment: SEC Form 10-K/A filed by Monopar Therapeutics Inc.
- Monopar Therapeutics Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits
- SEC Form 10-K filed by Monopar Therapeutics Inc.
- Monopar Reports Fourth Quarter and Full-Year 2025 Financial Results and Provides Business Update
Latest MRK
- EVP, Access, Policy & Comms Guindo Chirfi exercised 1,967 shares at a strike of $110.03 and covered exercise/tax liability with 969 shares, increasing direct ownership by 2% to 61,613 units (SEC Form 4)
- Exe V-P & Pres. MMD Chattopadhyay Sanat exercised 2,597 shares at a strike of $110.03 and covered exercise/tax liability with 1,130 shares, increasing direct ownership by 11% to 15,347 units (SEC Form 4)
- EVP&Pres, Merck Animal Heallth Deluca Richard R. exercised 2,518 shares at a strike of $110.03 and covered exercise/tax liability with 1,241 shares, increasing direct ownership by 0.80% to 161,537 units (SEC Form 4)
- EVP,Chief Info&Digital Officer Williams David Michael exercised 1,377 shares at a strike of $110.03 and covered exercise/tax liability with 679 shares, increasing direct ownership by 2% to 31,716 units (SEC Form 4)
- SVP Fin. - Global Controller Smart Dalton E. Iii exercised 1,408 shares at a strike of $110.33 and covered exercise/tax liability with 483 shares, increasing direct ownership by 11% to 9,137 units (SEC Form 4)
- Executive VP & President, MRL Li Dean Y covered exercise/tax liability with 2,326 shares and exercised 4,722 shares at a strike of $110.03, increasing direct ownership by 3% to 94,431 units (SEC Form 4)
- EVP, General Counsel Zachary Jennifer exercised 2,951 shares at a strike of $110.03 and covered exercise/tax liability with 1,454 shares, increasing direct ownership by 2% to 70,897 units (SEC Form 4)
- EVP, Chief HR Officer Larson Betty D exercised 13,435 shares at a strike of $110.81 and covered exercise/tax liability with 5,858 shares, increasing direct ownership by 122% to 13,774 units (SEC Form 4)
- EVP & CFO Litchfield Caroline exercised 3,935 shares at a strike of $110.03 and covered exercise/tax liability with 1,938 shares, increasing direct ownership by 2% to 92,301 units (SEC Form 4)
- Chairman, CEO & President Davis Robert M exercised 13,300 shares at a strike of $110.03 and covered exercise/tax liability with 6,551 shares, increasing direct ownership by 2% to 450,351 units (SEC Form 4)