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Compare · NVS vs UPB

NVS vs UPB

Side-by-side comparison of Novartis AG (NVS) and Upstream Bio Inc. (UPB): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both NVS and UPB operate in Biotechnology: Pharmaceutical Preparations (Health Care), so they compete in similar markets.
  • NVS is the larger of the two at $274.13B, about 660.2x UPB ($415.2M).
  • Over the past year, NVS is up 22.8% and UPB is down 30.2% - NVS leads by 53.0 points.
  • UPB has hit the wire 7 times in the past 4 weeks while NVS has been quiet.
  • NVS has more recent analyst coverage (25 ratings vs 9 for UPB).
PerformanceNVS+22.84%UPB-30.16%
2025-06-04+0.00%2026-06-03
MetricNVSUPB
Company
Novartis AG
Upstream Bio Inc.
Price
$143.69+0.15%
$7.62+5.32%
Market cap
$274.13B
$415.2M
1M return
-0.64%
-18.15%
1Y return
+22.84%
-30.16%
Industry
Biotechnology: Pharmaceutical Preparations
Biotechnology: Pharmaceutical Preparations
Exchange
NYSE
NASDAQ
IPO
2024
News (4w)
0
7
Recent ratings
25
9
NVS

Novartis AG

Novartis AG researches, develops, manufactures, and markets healthcare products worldwide. The company operates through two segments, Innovative Medicines and Sandoz. The Innovative Medicines segment offers prescription medicines for patients and healthcare providers. It also provides ophthalmology, neuroscience, immunology, hepatology and dermatology, respiratory, established, and cardiovascular, renal and metabolism medicine products. The Sandoz segment provides active ingredients and finished dosage forms of small molecule pharmaceuticals to third parties across a range of therapeutic areas, as well as finished dosage form anti-infectives. It also provides active pharmaceutical ingredients and intermediates primarily antibiotics; protein- or other biotechnology-based products, including biosimilars; and biotechnology manufacturing services. Novartis AG has a license and collaboration agreement with Alnylam Pharmaceuticals to develop, manufacture, and commercialize inclisiran; an agreement with CureVac to manufacture COVID-19 vaccine candidate CVnCoV; a collaboration with Artios Pharma Limited to create next generation DDR cancer therapies; and a clinical collaboration with Kura Oncology, Inc. to evaluate the combination of Tipifarnib and Alpelisib in patients with head and neck squamous cell carcinoma. The company was incorporated in 1996 and is headquartered in Basel, Switzerland.