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    Actuate Therapeutics to be Added to Russell 2000® Index

    11/26/24 8:00:00 AM ET
    $ACTU
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ACTU alert in real time by email

    CHICAGO and FORT WORTH, Texas, Nov. 26, 2024 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ:ACTU) ("Actuate" or the "Company"), a clinical-stage biopharmaceutical company focused on developing therapies for the treatment of high-impact, difficult-to-treat cancers announced today that the Company will be added to the Russell 2000® Index as part of the planned fourth quarter IPO additions effective after the U.S market opens on December 23, 2024.

    The Russell 2000® Index measures the performance of the small-cap segment of the US equity market. The Russell 2000® Index is a subset of the Russell 3000® Index representing approximately 10% of the total market capitalization of that index. It includes approximately 2,000 of the smallest securities based on a combination of their market cap and current index membership. Initial public offerings (IPOs) are added to the Russell US indexes on a quarterly basis. For more information on the Russell 2000® Index and the Preliminary List of IPO Additions: Russell US Index IPO additions and reports | LSEG

    About Actuate Therapeutics, Inc.

    Actuate is a clinical-stage biopharmaceutical company focused on developing therapies for the treatment of high-impact, difficult-to-treat cancers. Actuate's lead investigational drug product, elraglusib (a novel GSK-3β inhibitor), targets molecular pathways in cancer that are involved in promoting tumor growth and resistance to conventional cancer drugs such as chemotherapy including several DDR pathways. Elraglusib is designed to act as a mediator of anti-tumor immunity through the inhibition of NF-kB and regulates multiple immune checkpoints and immune cell function. For additional information, please visit the Company's website at http://www.actuatetherapeutics.com.

    Forward-Looking Statements

    This press release contains forward-looking statements about us, including our clinical trials, development plans, industry, and our planned addition of the Russell 2000® Index. The words "anticipate," "believe," "continue," "could," "estimate," "expect," "intend," "may," "might," "ongoing," "plan," "potential," "predict," "project," "should," "target," "will," "would," or the negative of these terms or other comparable terminology are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. All statements, other than statements related to present facts or current conditions or of historical facts, contained in this press release are forward-looking statements. Accordingly, these statements involve estimates, assumptions, substantial risks and uncertainties which could cause actual results to differ materially from those expressed in them, including but not limited to the potential benefits of and continued inclusion of the Company in the Russell 2000® Index, that clinical and preclinical drug development involves a lengthy and expensive process with uncertain timelines and outcomes, results of prior preclinical studies and early clinical trials are not necessarily predictive of future results, and elraglusib may not achieve favorable results in clinical trials or preclinical studies or receive regulatory approval on a timely basis, if at all; that we may not successfully enroll additional patients or establish or advance plans for further development; that elraglusib could be associated with side effects, adverse events or other properties or safety risks, which could delay or preclude regulatory approval, cause us to suspend or discontinue clinical trials or result in other negative consequences; our reliance on third parties to conduct our non-clinical studies and our clinical trials; our reliance on third-party licensors and ability to preserve and protect our intellectual property rights; that we face significant competition from other biotechnology and pharmaceutical companies; and our ability to fund development activities. In addition, any forward-looking statements are qualified in their entirety by reference to the factors discussed under the heading "Item 1A. Risk Factors" in our Quarterly Report on Form 10-Q for the quarter ended June 30, 2024 filed with the SEC on November 13, 2024 and other filings with the SEC. Because the risk factors referred to above could cause actual results or outcomes to differ materially from those expressed in any forward-looking statements made by us or on our behalf, you should not place undue reliance on any forward-looking statements. Further, any forward-looking statement speaks only as of the date on which it is made. New factors emerge from time to time, and it is not possible for us to predict which factors will arise. In addition, we cannot assess the impact of each factor on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements. Unless legally required, we do not undertake any obligation to release publicly any revisions to such forward-looking statements to reflect events or circumstances after the date of this press release or to reflect the occurrence of unanticipated events.

    Investor Contact

    Mike Moyer

    Managing Director

    LifeSci Advisors, LLC

    [email protected]



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    Q&A

    New
    • When will Actuate Therapeutics be added to the Russell 2000 Index?

      Actuate Therapeutics, Inc. will be added to the Russell 2000 Index effective after U.S. market opens on December 23, 2024.

    • What is the purpose of the Russell 2000 Index?

      The Russell 2000 Index is designed to measure the performance of the small-cap segment of the U.S. equity market, representing approximately 10% of the total market capitalization of the Russell 3000 Index.

    • What is Actuate Therapeutics' main area of focus?

      Actuate Therapeutics is focused on developing therapies for difficult-to-treat cancers, with its lead drug, elraglusib, being a GSK-3β inhibitor aimed at combatting tumor growth.

    • What does the lead drug elraglusib do?

      Elraglusib targets molecular pathways that promote tumor growth and is designed to enhance anti-tumor immunity by regulating immune checkpoints and cell functions, potentially improving chemotherapy efficacy.

    • What are some risks associated with Actuate Therapeutics' future developments as mentioned in the press release?

      Forward-looking statements could involve risks such as uncertain clinical outcomes, dependence on third parties, significant competition in the biotech industry, and the potential for adverse effects delaying drug approval.

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