CDTX insider transactions

Director Ra Capital Management, L.P. exercised 1,286,786 shares at a strike of $0.00 and returned $1,030,486,444 worth of shares to the company (4,652,309 units at $221.50) (SEC Form 4)

SEC Form 4 filed by Director Resnick Joshua

SEC Form 4 filed by Director Spencer Ryan

SEC Form 4 filed by Director Merson James

SEC Form 4 filed by Director Canale-Theakston Carin

Director Bassler Bonnie L returned $3,322 worth of shares to the company (15 units at $221.50), closing all direct ownership in the company (SEC Form 4)

Director Mineo Chrysa returned $735,380 worth of shares to the company (3,320 units at $221.50), closing all direct ownership in the company (SEC Form 4)

SEC Form 4 filed by Director Schroeder Theodore R

Director Burgess Daniel D returned $33,225 worth of shares to the company (150 units at $221.50) (SEC Form 4)

President & CEO Stein Jeffrey returned $16,754,260 worth of shares to the company (75,640 units at $221.50), closing all direct ownership in the company (SEC Form 4)

Chief Financial Officer Karbe Frank returned $1,667,009 worth of shares to the company (50,651 units at $32.91), closing all direct ownership in the company (SEC Form 4)

COO & CLO Ward Shane returned $5,555,884 worth of shares to the company (25,083 units at $221.50), closing all direct ownership in the company (SEC Form 4)

Chief Medical Officer Davarpanah Nicole Negar returned $2,780,490 worth of shares to the company (20,886 units at $133.13), closing all direct ownership in the company (SEC Form 4)

President & CEO Stein Jeffrey disposed of $339,040 worth of shares (5,190 units at $65.33), bought $339,040 worth of shares (4,262 units at $79.55), gifted 1,873 shares and received a gift of 937 shares, decreasing direct ownership by 44% to 5,763 units (SEC Form 4)

Chief Medical Officer Davarpanah Nicole Negar gifted 450 shares, decreasing direct ownership by 2% to 20,886 units (SEC Form 4)

President & CEO Stein Jeffrey gifted 51,379 shares and received a gift of 45,954 shares, decreasing direct ownership by 82% to 10,295 units (SEC Form 4)

President & CEO Stein Jeffrey covered exercise/tax liability with 2,285 shares, decreasing direct ownership by 4% to 56,199 units (SEC Form 4)

Chief Financial Officer Karbe Frank covered exercise/tax liability with 7,290 shares, decreasing direct ownership by 13% to 50,562 units (SEC Form 4)

COO & CLO Ward Shane covered exercise/tax liability with 15,041 shares, exercised 9,959 shares at a strike of $18.95 and sold $2,191,747 worth of shares (9,959 units at $220.08), decreasing direct ownership by 37% to 25,033 units (SEC Form 4)

Chief Medical Officer Davarpanah Nicole Negar covered exercise/tax liability with 10,332 shares, decreasing direct ownership by 33% to 21,286 units (SEC Form 4)

Chief Medical Officer Davarpanah Nicole Negar sold $29,797 worth of shares (474 units at $62.86), decreasing direct ownership by 1% to 31,418 units (SEC Form 4)

Director Ra Capital Management, L.P. bought $99,999,988 worth of shares (2,272,727 units at $44.00) (SEC Form 4)

SEC Form 4 filed by Director Ra Capital Management, L.P.

SEC Form 4 filed by Director Resnick Joshua

SEC Form 4 filed by Director Spencer Ryan

SEC Form 4 filed by Director Schroeder Theodore R

SEC Form 4 filed by Director Mineo Chrysa

SEC Form 4 filed by Director Merson James

SEC Form 4 filed by Director Canale-Theakston Carin

SEC Form 4 filed by Director Burgess Daniel D

SEC Form 4 filed by Director Bassler Bonnie L

Director Mineo Chrysa bought $73,896 worth of shares (3,320 units at $22.26) (SEC Form 4)

Chief Medical Officer Davarpanah Nicole Negar was granted 10,000 shares, increasing direct ownership by 46% to 31,692 units (SEC Form 4)

New insider Davarpanah Nicole Negar claimed ownership of 21,692 shares (SEC Form 3)

SEC Form 4 filed by President & CEO Stein Jeffrey

COO & CLO Ward Shane was granted 25,000 shares, increasing direct ownership by 170% to 39,674 units (SEC Form 4)

COO & CLO Ward Shane sold $36,542 worth of shares (1,664 units at $21.96), decreasing direct ownership by 10% to 14,674 units (SEC Form 4)

CHIEF SCIENTIFIC OFFICER Tari Leslie sold $38,940 worth of shares (1,773 units at $21.96), decreasing direct ownership by 10% to 16,215 units (SEC Form 4)

Chief Financial Officer Karbe Frank was granted 57,500 shares (SEC Form 4)

SEC Form 3 filed by new insider Karbe Frank

SEC Form 4 filed by Director Resnick Joshua

SEC Form 3 filed by new insider Resnick Joshua

SEC Form 4 filed by Director Ra Capital Management, L.P.

SEC Form 4 filed by Director Burgess Daniel D

SEC Form 4 filed by Director Schroeder Theodore R

SEC Form 4 filed by Director Mineo Chrysa

SEC Form 4 filed by Director Bassler Bonnie L

SEC Form 4 filed by Director Canale-Theakston Carin

Director Ra Capital Management, L.P. was granted 389,716 shares (SEC Form 4)

SEC Form 4 filed by Chief Medical Officer Sandison Taylor

SEC Form 4 filed by CHIEF SCIENTIFIC OFFICER Tari Leslie

SEC Form 4 filed by President & CEO Stein Jeffrey

SEC Form 4 filed by Chief Financial Officer Shah Preetam

SEC Form 4 filed by COO & CLO Ward Shane

Chief Medical Officer Sandison Taylor sold $10,752 worth of shares (924 units at $11.64), decreasing direct ownership by 4% to 23,067 units (SEC Form 4)

CHIEF SCIENTIFIC OFFICER Tari Leslie sold $10,580 worth of shares (909 units at $11.64), decreasing direct ownership by 5% to 17,788 units (SEC Form 4)

Director Ra Capital Management, L.P. converted options into 703,080 shares (SEC Form 4)

Amendment: SEC Form 4 filed by Director Ra Capital Management, L.P.

SEC Form 4 filed by Director Ra Capital Management, L.P.

SEC Form 4 filed by Director Burgess Daniel D