CRNX insider transactions

Director Deardorf Caren was granted 5,925 shares, increasing direct ownership by 36% to 22,225 units (SEC Form 4)

Director Fust Matthew K was granted 5,925 shares, increasing direct ownership by 26% to 28,761 units (SEC Form 4)

Director Nichols Weston was granted 5,925 shares, increasing direct ownership by 36% to 22,225 units (SEC Form 4)

Director Vivaldi Coelho Rogerio was granted 5,925 shares, increasing direct ownership by 36% to 22,225 units (SEC Form 4)

Director Bedrosian Camille L was granted 5,925 shares, increasing direct ownership by 36% to 22,225 units (SEC Form 4)

Director Wierenga Wendell was granted 5,925 shares, increasing direct ownership by 5% to 122,071 units (SEC Form 4)

Director Okey Stephanie was granted 5,925 shares, increasing direct ownership by 93% to 12,325 units (SEC Form 4)

Director Okey Stephanie sold $246,143 worth of shares (6,900 units at $35.67) as part of a pre-agreed trading plan, decreasing direct ownership by 52% to 6,400 units (SEC Form 4)

President & CEO Struthers Richard Scott gifted 968,800 shares and received a gift of 968,800 shares (SEC Form 4)

SEC Form 4 filed by Knight Jeff E.

SEC Form 4 filed by Crinetics Pharmaceuticals Inc.

SEC Form 4 filed by Knight Jeff E.

SEC Form 4 filed by Struthers Richard Scott

Director Vivaldi Coelho Rogerio sold $180,761 worth of shares (5,000 units at $36.15), decreasing direct ownership by 23% to 16,300 units (SEC Form 4)

Director Okey Stephanie sold $119,010 worth of shares (3,000 units at $39.67), decreasing direct ownership by 18% to 13,300 units (SEC Form 4)

Chief Financial Officer Schilke Tobin sold $266,305 worth of shares (6,713 units at $39.67), decreasing direct ownership by 8% to 78,121 units (SEC Form 4)

President & CEO Struthers Richard Scott was granted 62,000 shares, increasing direct ownership by 17% to 426,759 units (SEC Form 4)

Chief Financial Officer Schilke Tobin was granted 32,000 shares, increasing direct ownership by 61% to 84,834 units (SEC Form 4)

Chief Operating Officer Knight Jeff E. was granted 34,000 shares, increasing direct ownership by 39% to 121,929 units (SEC Form 4)

Chief Scientific Officer Betz Stephen F. was granted 30,000 shares, increasing direct ownership by 25% to 147,713 units (SEC Form 4)

Chief Commercial Officer Kalofonos Isabel was granted 34,000 shares, increasing direct ownership by 4,077% to 34,834 units (SEC Form 4)

Chief Commercial Officer Kalofonos Isabel exercised 2,500 shares at a strike of $40.59 and sold $137,500 worth of shares (2,500 units at $55.00) (SEC Form 4)

Chief Scientific Officer Betz Stephen F. exercised 18,000 shares at a strike of $1.91, increasing direct ownership by 18% to 117,713 units (SEC Form 4)

President & CEO Struthers Richard Scott exercised 44,742 shares at a strike of $13.09, increasing direct ownership by 14% to 364,759 units (SEC Form 4)

Chief Med and Dev Officer Pizzuti Dana exercised 5,000 shares at a strike of $16.89 and sold $225,100 worth of shares (5,000 units at $45.02) (SEC Form 4)

Chief Med and Dev Officer Pizzuti Dana exercised 5,000 shares at a strike of $16.89 and sold $213,312 worth of shares (5,000 units at $42.66) (SEC Form 4)

Chief Med and Dev Officer Pizzuti Dana exercised 5,000 shares at a strike of $16.89 and sold $209,050 worth of shares (5,000 units at $41.81) (SEC Form 4)

President & CEO Struthers Richard Scott sold $180,000 worth of shares (4,000 units at $45.00) (SEC Form 4)

Director Fust Matthew K exercised 10,000 shares at a strike of $1.91 and sold $716,000 worth of shares (16,000 units at $44.75), decreasing direct ownership by 21% to 22,836 units (SEC Form 4)

Chief Med and Dev Officer Pizzuti Dana exercised 5,000 shares at a strike of $16.89 and sold $160,500 worth of shares (5,000 units at $32.10) (SEC Form 4)

Chief Med and Dev Officer Pizzuti Dana exercised 30,000 shares at a strike of $16.89 and sold $912,900 worth of shares (30,000 units at $30.43) (SEC Form 4)

Chief Med and Dev Officer Pizzuti Dana sold $189,437 worth of shares (6,492 units at $29.18), decreasing direct ownership by 9% to 66,270 units (SEC Form 4)

Chief Scientific Officer Betz Stephen F. exercised 88,170 shares at a strike of $3.30 and sold $3,141,877 worth of shares (97,483 units at $32.23), decreasing direct ownership by 9% to 99,713 units (SEC Form 4)

Director Deardorf Caren was granted 6,900 shares, increasing direct ownership by 73% to 16,300 units (SEC Form 4)

Director Okey Stephanie was granted 6,900 shares, increasing direct ownership by 73% to 16,300 units (SEC Form 4)

Director Vivaldi Coelho Rogerio was granted 6,900 shares, increasing direct ownership by 48% to 21,300 units (SEC Form 4)

Director Bedrosian Camille L was granted 6,900 shares, increasing direct ownership by 73% to 16,300 units (SEC Form 4)

Director Nichols Weston was granted 6,900 shares, increasing direct ownership by 73% to 16,300 units (SEC Form 4)

Director Wierenga Wendall was granted 6,900 shares, increasing direct ownership by 6% to 116,146 units (SEC Form 4)

Director Fust Matthew K was granted 6,900 shares, increasing direct ownership by 31% to 28,836 units (SEC Form 4)

President & CEO Struthers Richard Scott gifted 90,400 shares and received a gift of 90,400 shares, decreasing direct ownership by 22% to 320,017 units (SEC Form 4)

President & CEO Struthers Richard Scott exercised 81,270 shares at a strike of $1.91, increasing direct ownership by 25% to 410,417 units (SEC Form 4)

Chief Med and Dev Officer Pizzuti Dana sold $86,021 worth of shares (2,515 units at $34.20), decreasing direct ownership by 3% to 72,233 units (SEC Form 4)

Chief Operating Officer Knight Jeff E. sold $244,964 worth of shares (7,162 units at $34.20), decreasing direct ownership by 8% to 87,491 units (SEC Form 4)

Chief Scientific Officer Betz Stephen F. sold $197,353 worth of shares (5,770 units at $34.20), decreasing direct ownership by 5% to 108,588 units (SEC Form 4)

President & CEO Struthers Richard Scott sold $593,017 worth of shares (17,338 units at $34.20), decreasing direct ownership by 5% to 329,147 units (SEC Form 4)

Chief Financial Officer Schilke Tobin was granted 52,000 shares (SEC Form 4)

SEC Form 3 filed by new insider Schilke Tobin

President & CEO Struthers Richard Scott was granted 89,000 shares, increasing direct ownership by 35% to 346,485 units (SEC Form 4)

Chief Operating Officer Knight Jeff E. was granted 43,000 shares, increasing direct ownership by 83% to 94,653 units (SEC Form 4)

Chief Med and Dev Officer Pizzuti Dana was granted 43,000 shares, increasing direct ownership by 135% to 74,748 units (SEC Form 4)

Chief Scientific Officer Betz Stephen F. was granted 43,000 shares, increasing direct ownership by 60% to 114,358 units (SEC Form 4)

Chief Med and Dev Officer Pizzuti Dana exercised 5,000 shares at a strike of $16.89 and sold $195,350 worth of shares (5,000 units at $39.07) (SEC Form 4)

Betz Stephen F. acquired $6,756 worth of shares (451 units at $14.98), increasing direct ownership by 0.64% to 71,358 units (SEC Form 5)

Wilson Marc acquired $7,086 worth of shares (473 units at $14.98), increasing direct ownership by 0.43% to 111,565 units (SEC Form 5)

SEC Form 4 filed by Chief Commercial Officer Kalofonos Isabel

Chief Med and Dev Officer Pizzuti Dana exercised 17,500 shares at a strike of $17.28 and sold $781,350 worth of shares (15,000 units at $52.09), increasing direct ownership by 9% to 31,748 units (SEC Form 4)

SEC Form 3 filed by new insider Kalofonos Isabel

Chief Scientific Officer Betz Stephen F. exercised 2,331 shares at a strike of $1.91, increasing direct ownership by 3% to 71,358 units (SEC Form 4)

President & CEO Struthers Richard Scott sold $575,700 worth of shares (10,000 units at $57.57) (SEC Form 4)