OPRX insider transactions

Chief Commercial Officer Greco Theresa covered exercise/tax liability with 1,793 shares, decreasing direct ownership by 2% to 71,075 units (SEC Form 4) (withholding obligation)

Chief Executive Officer Silvestro Stephen L covered exercise/tax liability with 5,219 shares, decreasing direct ownership by 3% to 185,288 units (SEC Form 4) to satisfy withholding tax

SEC Form 3 filed by new insider Presti Mariyamma Varghese

Chief Legal & Admin Officer Odence-Ford Marion converted options into 4,000 shares and covered exercise/tax liability with 1,386 shares, increasing direct ownership by 3% to 91,936 units (SEC Form 4)

Amendment: Chief Executive Officer Silvestro Stephen L covered exercise/tax liability with 3,361 shares, decreasing direct ownership by 2% to 190,507 units (SEC Form 4)

Chief Commercial Officer Greco Theresa covered exercise/tax liability with 1,420 shares, decreasing direct ownership by 2% to 72,868 units (SEC Form 4)

Chief Executive Officer Silvestro Stephen L covered exercise/tax liability with 3,361 shares, decreasing direct ownership by 2% to 190,507 units (SEC Form 4)

Chief Legal & Admin Officer Odence-Ford Marion covered exercise/tax liability with 4,051 shares, decreasing direct ownership by 4% to 89,322 units (SEC Form 4)

Chief Product & Tech Officer Besch Doug covered exercise/tax liability with 4,079 shares, decreasing direct ownership by 6% to 66,876 units (SEC Form 4)

Chief Finance & Strat Officer Stelmakh Edward covered exercise/tax liability with 3,658 shares, decreasing direct ownership by 3% to 123,172 units (SEC Form 4)

Amendment: Chief Finance & Strat Officer Stelmakh Edward converted options into 5,237 shares and covered exercise/tax liability with 1,388 shares, increasing direct ownership by 3% to 126,830 units (SEC Form 4)

Chief Finance & Strat Officer Stelmakh Edward converted options into 5,237 shares and sold $18,752 worth of shares (1,388 units at $13.51), increasing direct ownership by 3% to 126,830 units (SEC Form 4)

Chief Executive Officer Silvestro Stephen L converted options into 6,546 shares and covered exercise/tax liability with 1,594 shares, increasing direct ownership by 3% to 193,868 units (SEC Form 4)

Chief Legal & Admin Officer Odence-Ford Marion converted options into 3,928 shares and covered exercise/tax liability with 1,153 shares, increasing direct ownership by 3% to 93,373 units (SEC Form 4)

CHIEF OPERATING OFFICER Merrell Brendan W. covered exercise/tax liability with 289 shares, decreasing direct ownership by 1% to 26,207 units (SEC Form 4)

Chief Business Officer D'Silva Andrew J. covered exercise/tax liability with 703 shares, decreasing direct ownership by 2% to 44,735 units (SEC Form 4)

Chief Product & Tech Officer Besch Doug converted options into 1,964 shares and covered exercise/tax liability with 581 shares, increasing direct ownership by 2% to 70,955 units (SEC Form 4)

CHIEF OPERATING OFFICER Merrell Brendan W. covered exercise/tax liability with 712 shares, decreasing direct ownership by 3% to 26,496 units (SEC Form 4)

Chief Business Officer D'Silva Andrew J. covered exercise/tax liability with 868 shares, decreasing direct ownership by 2% to 45,438 units (SEC Form 4)

CHIEF OPERATING OFFICER Merrell Brendan W. was granted 10,417 shares and covered exercise/tax liability with 483 shares, increasing direct ownership by 58% to 27,208 units (SEC Form 4)

New insider Merrell Brendan W. claimed ownership of 17,274 shares (SEC Form 3)

Chief Business Officer D'Silva Andrew J. covered exercise/tax liability with 1,208 shares, decreasing direct ownership by 3% to 46,306 units (SEC Form 4)

Chief Commercial Officer Greco Theresa covered exercise/tax liability with 1,693 shares, decreasing direct ownership by 2% to 74,288 units (SEC Form 4)

Chief Legal & Admin Officer Odence-Ford Marion converted options into 6,649 shares and covered exercise/tax liability with 1,952 shares, increasing direct ownership by 5% to 90,598 units (SEC Form 4)

Chief Executive Officer Silvestro Stephen L converted options into 6,649 shares and sold $30,375 worth of shares (1,620 units at $18.75), increasing direct ownership by 3% to 188,916 units (SEC Form 4)

Chief Finance & Strat Officer Stelmakh Edward converted options into 16,623 shares and covered exercise/tax liability with 4,406 shares, increasing direct ownership by 11% to 122,981 units (SEC Form 4)

Chief Product & Tech Officer Besch Doug converted options into 3,325 shares and covered exercise/tax liability with 983 shares, increasing direct ownership by 3% to 69,572 units (SEC Form 4)

Chief Business Officer D'Silva Andrew J. was granted 10,417 shares, increasing direct ownership by 28% to 47,514 units (SEC Form 4)

New insider D'Silva Andrew J. claimed ownership of 37,097 shares (SEC Form 3)

Director Spangler Patrick D sold $194,489 worth of shares (11,120 units at $17.49), decreasing direct ownership by 20% to 44,215 units (SEC Form 4)

Chief Executive Officer Silvestro Stephen L was granted 15,625 shares, increasing direct ownership by 9% to 183,887 units (SEC Form 4)

Chief Legal & Admin Officer Odence-Ford Marion was granted 15,625 shares, increasing direct ownership by 22% to 85,901 units (SEC Form 4)

CFO/COO Stelmakh Edward was granted 15,625 shares, increasing direct ownership by 16% to 110,764 units (SEC Form 4)

Chief Commercial Officer Greco Theresa was granted 15,625 shares, increasing direct ownership by 26% to 75,981 units (SEC Form 4)

Chief Prod & Tech Officer Besch Doug was granted 15,625 shares, increasing direct ownership by 30% to 67,230 units (SEC Form 4)

Director Klema Cathy was granted 9,868 shares, increasing direct ownership by 84% to 21,620 units (SEC Form 4)

Director Lang James Paul was granted 9,868 shares, increasing direct ownership by 3% to 399,320 units (SEC Form 4)

Director Spangler Patrick D was granted 9,868 shares, increasing direct ownership by 22% to 55,335 units (SEC Form 4)

Director Vos Ellen O'Connor was granted 9,868 shares, increasing direct ownership by 16% to 72,642 units (SEC Form 4)

Director Wasson Gregory D was granted 9,868 shares, increasing direct ownership by 21% to 57,183 units (SEC Form 4)

Chief Commercial Officer Greco Theresa was granted 9,483 shares, increasing direct ownership by 19% to 60,356 units (SEC Form 4)

Chief Commercial Officer Silvestro Stephen L was granted 46,948 shares, increasing direct ownership by 39% to 168,262 units (SEC Form 4)

Director Lang James Paul bought $2,443,761 worth of shares (321,408 units at $7.60), increasing direct ownership by 472% to 389,452 units (SEC Form 4)

Chief Commercial Officer Silvestro Stephen L converted options into 1,928 shares and covered exercise/tax liability with 572 shares, increasing direct ownership by 1% to 121,314 units (SEC Form 4)

Chief Legal Officer & CHRO Odence-Ford Marion converted options into 771 shares and covered exercise/tax liability with 268 shares, increasing direct ownership by 0.72% to 70,276 units (SEC Form 4)

CEO Febbo William J covered exercise/tax liability with 401 shares, decreasing direct ownership by 0.07% to 600,852 units (SEC Form 4)

CFO/COO Stelmakh Edward covered exercise/tax liability with 2,156 shares, decreasing direct ownership by 2% to 95,139 units (SEC Form 4)

Chief Product Officer Besch Doug covered exercise/tax liability with 1,386 shares, decreasing direct ownership by 3% to 51,605 units (SEC Form 4)

Chief Commercial Officer Silvestro Stephen L covered exercise/tax liability with 2,298 shares, decreasing direct ownership by 2% to 119,958 units (SEC Form 4)

Chief Legal Officer & CHRO Odence-Ford Marion covered exercise/tax liability with 1,479 shares, decreasing direct ownership by 2% to 69,773 units (SEC Form 4)

General Counsel and CCO Odence-Ford Marion converted options into 4,000 shares and covered exercise/tax liability with 1,386 shares, increasing direct ownership by 4% to 71,252 units (SEC Form 4)

Director Klema Cathy converted options into 5,109 shares, increasing direct ownership by 77% to 11,752 units (SEC Form 4)

CFO/COO Stelmakh Edward was granted 41,408 shares, increasing direct ownership by 74% to 97,295 units (SEC Form 4)

Amendment: CFO/COO Stelmakh Edward was granted 0 shares (SEC Form 4)

Chief Commercial Officer Silvestro Stephen L was granted 41,408 shares, increasing direct ownership by 51% to 122,256 units (SEC Form 4)

Chief Commercial Officer Greco Theresa was granted 15,528 shares, increasing direct ownership by 44% to 50,873 units (SEC Form 4)

General Counsel and CCO Odence-Ford Marion was granted 41,408 shares, increasing direct ownership by 152% to 68,638 units (SEC Form 4)

Chief Product Officer Besch Doug was granted 41,408 shares, increasing direct ownership by 357% to 52,991 units (SEC Form 4)

General Counsel and CCO Odence-Ford Marion converted options into 3,927 shares and covered exercise/tax liability with 1,153 shares, increasing direct ownership by 11% to 27,230 units (SEC Form 4)

Chief Commercial Officer Silvestro Stephen L converted options into 6,546 shares and covered exercise/tax liability with 2,576 shares, increasing direct ownership by 5% to 80,848 units (SEC Form 4)