• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Dashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlerts
    Company
    AboutQuantisnow PlusContactJobs
    Legal
    Terms of usePrivacy policyCookie policy

    4D Molecular Therapeutics Announces Resignation of Professor David Schaffer, Ph.D. from the Company's Board of Directors

    2/22/22 4:02:00 PM ET
    $FDMT
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $FDMT alert in real time by email

    EMERYVILLE, Calif., Feb. 22, 2022 (GLOBE NEWSWIRE) -- 4D Molecular Therapeutics (NASDAQ:FDMT), a clinical-stage gene therapy company harnessing the power of directed evolution for targeted gene therapies announced that Professor David Schaffer, Ph.D. has resigned as a director of 4D Molecular Therapeutics.

    Professor Schaffer's transition coincides with the evolution of 4DMT into a clinical-stage gene therapy company with five products in clinical development and plans to develop pre-commercial and late-stage clinical-regulatory capabilities, in addition to our on-going internal vector invention and GMP manufacturing platforms. Professor Schaffer was recently appointed Director of California Institute for Quantitative Biosciences (QB3) at U.C. Berkeley, and Deputy Director of the Bakar Labs at the Bakar BioEnginuity Hub, and he continues as Professor of Chemical and Biomolecular Engineering, Bioengineering, Molecular and Cell Biology at U.C. Berkeley. In addition to these major new roles, Professor Schaffer plans to pursue other early-stage technology opportunities outside of AAV gene therapy. For nearly nine years since company formation in 2013, Professor Schaffer served on the 4DMT board of directors.

    "On behalf of the company and the entire board, I would like to thank David for his service and extraordinary contributions to the 4DMT founding team and Board of Directors over roughly nine years," said David Kirn, M.D., Co-Founder and Chief Executive Officer of 4DMT. "David's contributions supported the company's growth from a scientific platform company into a diversified clinical development stage company with a robust product pipeline and five products in clinical development, as well as strong platforms for vector invention, product engineering and GMP manufacturing."

    "It has been an honor to help 4D grow since 2013," said David Schaffer, PhD. "4D has grown and evolved into a leading clinical-stage next-generation gene therapy company. I leave knowing that the Board of Directors has been strengthened greatly by the recent additions of four independent and deeply experienced directors, including adding expertise in product commercialization, business development and finance. Additionally, the Therapeutic Vector Evolution platform is in the hands of an outstanding team that has improved and expanded the original technology. I would like to thank the entire board, the company and our shareholders for many years of success together. I'm looking forward to new opportunities, including in my recently announced leadership positions with QB3 and the Bakar Labs at UC Berkeley."

    About 4DMT

    4DMT is a clinical-stage company harnessing the power of directed evolution for targeted gene therapies. 4DMT seeks to unlock the full potential of gene therapy using its platform, Therapeutic Vector Evolution, which combines the power of directed evolution with approximately one billion synthetic capsid sequences to invent evolved vectors for use in targeted gene therapy products. The company is initially focused on five clinical-stage products in three therapeutic areas: ophthalmology, cardiology (including Fabry disease) and pulmonology. The 4DMT targeted and evolved vectors are invented with the goal of being delivered through clinically routine, well-tolerated and minimally invasive routes of administration, transducing diseased cells in target tissues efficiently, having reduced immunogenicity and, where relevant, having resistance to pre-existing antibodies. The five 4DMT product candidates in clinical development are : 4D-310 for Fabry disease, 4D-150 for wet AMD, 4D-125 for XLRP, 4D-110 for choroideremia and 4D-710 for cystic fibrosis.

    Contacts:

    Media:

    Carolyne Zimmermann

    Chief Business Officer

    [email protected]

    Investors:

    Mike Zanoni

    VP, Investor Relations

    [email protected]



    Primary Logo

    Get the next $FDMT alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $FDMT

    DatePrice TargetRatingAnalyst
    1/13/2025$40.00 → $15.00Outperform → Market Perform
    BMO Capital Markets
    11/21/2024$8.00Underweight
    Morgan Stanley
    9/23/2024Overweight → Neutral
    Cantor Fitzgerald
    4/15/2024$45.00Overweight
    Barclays
    4/15/2024$459.00Overweight
    Barclays
    2/7/2024$81.00Buy
    Goldman
    10/26/2023$25.00Outperform
    RBC Capital Mkts
    10/24/2023$32.00Overweight
    Cantor Fitzgerald
    More analyst ratings

    $FDMT
    Leadership Updates

    Live Leadership Updates

    See more
    • 4DMT Advances Leadership in Large Market Ophthalmology with Senior Management Hires and Formation of Ophthalmology Advisory Board

      Dhaval Desai, PharmD, named as Chief Development Officer; will oversee late-stage Product Development, Medical Affairs, Scientific Communications, Regulatory and Quality operations; most recently SVP & Chief Development Officer at Iveric Bio where he led development and approval of IZERVAYChristopher Simms named as Chief Commercial Officer, effective September 25, 2024; will oversee Pre-commercial and Commercial organizations, pre-launch preparations and development; most recently SVP & Chief Commercial Officer at Iveric Bio where he led commercial strategy and execution for the launch of IZERVAYCarlos Quezada-Ruiz, M.D., FASRS, named as SVP, Therapeutic Area Head, Ophthalmology; will lead t

      8/5/24 8:00:00 AM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • 4DMT Highlights Recent Clinical Pipeline Progress, Near-Term Milestones and Organizational Updates

      Poised for multiple meaningful catalysts in 2024 driven by strong clinical progress across large market programs in wet age-related macular degeneration (wet AMD), diabetic macular edema (DME) and cystic fibrosis (CF)Established next-generation AAV & CRISPR/Cas-based genetic medicines partnership for central nervous system (CNS) diseases with Arbor BiotechnologiesAnnounced organizational updates, including the appointment of UCSF Professor Noriyuki Kasahara (Nori), M.D., Ph.D. as Chief Scientific OfficerWell capitalized ending 2023 with $300 million in estimated cash, financial runway guidance unchanged and cash expected to be sufficient to fund operations into H1 2026 EMERYVILLE, Calif

      1/4/24 8:00:00 AM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • 4DMT Appoints Uneek Mehra as Chief Financial and Business Officer

      EMERYVILLE, Calif., Sept. 12, 2023 (GLOBE NEWSWIRE) -- 4D Molecular Therapeutics (NASDAQ:FDMT, 4DMT or the Company))), a clinical-stage biotherapeutics company harnessing the power of directed evolution for targeted genetic medicines, today announced the appointment of Uneek Mehra as Chief Financial & Business Officer of 4DMT. Mr. Mehra will succeed August J. Moretti, J.D., who is retiring, and has agreed to serve in an advisory capacity to support Mr. Mehra's transition. Mr. Mehra will lead 4DMT's finance, business development, and precommercial functions and will be a member of 4DMT's Executive Team, reporting to David Kirn, M.D., Co-founder and Chief Executive Officer of 4DMT. Mr. Mehr

      9/12/23 4:05:00 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FDMT
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • 4DMT Announces New Employment Inducement Grants

      EMERYVILLE, Calif., May 16, 2025 (GLOBE NEWSWIRE) -- 4D Molecular Therapeutics (NASDAQ:FDMT, 4DMT or the Company)), a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented benefits to patients, today announced that on May 13, 2025, the compensation committee of the Company's board of directors granted eight new non-executive employees 31,800 Restricted Stock Units (RSUs). The RSUs were granted pursuant to the Company's 2025 Employment Inducement Award Plan, which was approved by the Company's board of directors in February 2025 under Rule 5635(c)(4) of The Nasdaq Global Market f

      5/16/25 4:05:00 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • 4DMT Reports First Quarter 2025 Financial Results, Operational Highlights and Expected Upcoming Milestones

      Enrolled first patients in first 4D-150 Phase 3 clinical trial (4FRONT-1) in wet AMD, with over 50 clinical trial sites open to dateInitiation of second 4D-150 Phase 3 clinical trial (4FRONT-2) expected in Q3 2025, with topline data from both 4FRONT-1 and 4FRONT-2 expected in H2 2027RMAT designation received from FDA for 4D-150 in DME, adding to previous regulatory designations of RMAT and PRIME (EMA) for 4D-150 in wet AMD$458 million in cash, cash equivalents, and marketable securities as of March 31, 2025, expected to fund planned operations into 2028 EMERYVILLE, Calif., May 08, 2025 (GLOBE NEWSWIRE) -- 4D Molecular Therapeutics (NASDAQ:FDMT, 4DMT or the Company)), a leading late-stage

      5/8/25 4:04:02 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • 4DMT to Participate in Upcoming Investor Conferences

      EMERYVILLE, Calif., May 05, 2025 (GLOBE NEWSWIRE) -- 4D Molecular Therapeutics (NASDAQ:FDMT, 4DMT or the Company)), a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented benefits to patients, today announced that management will participate in fireside chats at upcoming investor conferences in May. Members of the management team will also be available for one-on-one meetings. BofA Securities 2025 Healthcare Conference Presentation Date:Wednesday, May 14, 2025Presentation Time:2:20 p.m. PTWebcast Link:Webcast   RBC Capital Markets 2025 Global Healthcare Conference Presentatio

      5/5/25 8:00:21 AM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FDMT
    Financials

    Live finance-specific insights

    See more
    • 4DMT Acquires Complement Pathway Inhibitor Payload for 4D-175 Product Candidate for Geographic Atrophy

      4DMT acquires all world-wide rights to short-form human complement factor H (sCFH) from Aevitas Therapeutics, Inc.; technology invented at University of PennsylvaniaAnnounces sCFH as payload for 4D-175 lead product candidate for geographic atrophy (GA); sCFH extensively characterized in 3 genetic mouse models and in non-human primates (NHP)CFH variants with reduced complement inhibitory function are a well-validated genetic risk factor for GA secondary to age-related macular degeneration (AMD), with approximately 75% of AMD patients carrying a high-risk variant of CFH; utilizing a precision medicine approach, this population represents a potential target population for 4D-175Continues expans

      4/24/23 8:00:00 AM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • 4D Molecular Therapeutics Presents Interim Data from 4D-310 INGLAXA Phase 1/2 Clinical Trials & Development Plans for Fabry Disease Cardiomyopathy at WORLDSymposium™

      All three patients with 12 months of follow-up demonstrated improvement in multiple FDA-recommended cardiac endpoints at relatively low dose of 1E13 vg/kgCardiac biopsy demonstrated selective and widespread transgene expression within ~50% of cardiomyocytes Engaging with FDA to lift clinical hold and resume enrollment with updated exclusion criteria and highly effective rituximab/sirolimus immunosuppressive regimen to reduce risk of atypical hemolytic uremic syndrome ("aHUS")Otherwise, generally well-tolerated with no liver, heart, or dorsal root ganglia ("DRG") toxicity observedCompany to host live webcast today at 4:30 p.m. EST EMERYVILLE, Calif., Feb. 22, 2023 (GLOBE NEWSWIRE) -- 4D Mo

      2/22/23 4:05:00 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • 4D Molecular Therapeutics Announces Interim Clinical Data from On-going Phase 1/2 Clinical Trial of Intravitreal 4D-150 for Wet Age-Related Macular Degeneration (wet AMD)

      Cohort 1 patients (n=5) received a single intravitreal injection of 4D-150 (3E10 vg/eye); these patients were high need patients who in the 12 months preceding trial enrollment had a mean annualized anti-VEGF injection rate of ~11Following intravitreal 4D-150, Cohort 1 patients' annualized anti-VEGF injection rate was reduced by 96.7%80% of Cohort 1 patients had not received any supplemental aflibercept injections for up to ~10 months after 4D-150 dosingCohort 1 safety and tolerability of 4D-150 demonstrated to date, with no clinically significant intraocular inflammation or hypotony reportedConference call & webcast to be held Monday November 14, 2022 at 8:00 AM E.T. EMERYVILLE, Calif.

      11/14/22 7:30:00 AM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FDMT
    SEC Filings

    See more
    • Amendment: SEC Form SCHEDULE 13G/A filed by 4D Molecular Therapeutics Inc.

      SCHEDULE 13G/A - 4D Molecular Therapeutics, Inc. (0001650648) (Subject)

      5/15/25 4:29:12 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form S-8 filed by 4D Molecular Therapeutics Inc.

      S-8 - 4D Molecular Therapeutics, Inc. (0001650648) (Filer)

      5/8/25 4:33:39 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form 10-Q filed by 4D Molecular Therapeutics Inc.

      10-Q - 4D Molecular Therapeutics, Inc. (0001650648) (Filer)

      5/8/25 4:21:40 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FDMT
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • Amendment: SEC Form SC 13G/A filed by 4D Molecular Therapeutics Inc.

      SC 13G/A - 4D Molecular Therapeutics, Inc. (0001650648) (Subject)

      11/15/24 5:05:27 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Amendment: SEC Form SC 13G/A filed by 4D Molecular Therapeutics Inc.

      SC 13G/A - 4D Molecular Therapeutics, Inc. (0001650648) (Subject)

      11/14/24 5:46:12 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Amendment: SEC Form SC 13G/A filed by 4D Molecular Therapeutics Inc.

      SC 13G/A - 4D Molecular Therapeutics, Inc. (0001650648) (Subject)

      11/14/24 4:31:18 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FDMT
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • 4D Molecular Therapeutics downgraded by BMO Capital Markets with a new price target

      BMO Capital Markets downgraded 4D Molecular Therapeutics from Outperform to Market Perform and set a new price target of $15.00 from $40.00 previously

      1/13/25 7:43:59 AM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Morgan Stanley initiated coverage on 4D Molecular Therapeutics with a new price target

      Morgan Stanley initiated coverage of 4D Molecular Therapeutics with a rating of Underweight and set a new price target of $8.00

      11/21/24 7:33:52 AM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • 4D Molecular Therapeutics downgraded by Cantor Fitzgerald

      Cantor Fitzgerald downgraded 4D Molecular Therapeutics from Overweight to Neutral

      9/23/24 7:31:34 AM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $FDMT
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • SEC Form 4 filed by Chief Legal Officer Bizily Scott

      4 - 4D Molecular Therapeutics, Inc. (0001650648) (Issuer)

      3/10/25 8:00:20 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form 4 filed by Chief Executive Officer Kirn David

      4 - 4D Molecular Therapeutics, Inc. (0001650648) (Issuer)

      3/10/25 7:58:59 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form 4 filed by Chief Medical Officer Kim Robert Young

      4 - 4D Molecular Therapeutics, Inc. (0001650648) (Issuer)

      3/10/25 7:58:05 PM ET
      $FDMT
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care