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    Amendment: SEC Form S-1/A filed by HCW Biologics Inc.

    5/13/25 4:18:06 PM ET
    $HCWB
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $HCWB alert in real time by email
    S-1/A 1 d937560ds1a.htm S-1/A S-1/A

    As filed with the U.S. Securities and Exchange Commission on May 13, 2025

    Registration No. 333-287136

     

     
     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION 

    WASHINGTON, D.C. 20549

     

     

    Pre-Effective Amendment No. 1

    to

    FORM S-1

    REGISTRATION STATEMENT

    UNDER

    THE SECURITIES ACT OF 1933

     

     

    HCW BIOLOGICS INC.

    (Exact name of Registrant as specified in its charter)

     

     

     

     

    Delaware   2834   82-5024477
    (State or Other Jurisdiction of
    Incorporation or Organization)
      Primary Standard Industrial
    Classification Code Number
     

    (I.R.S. Employer

    Identification Number)

    2929 N Commerce Parkway

    Miramar, FL 33025

    (954) 842-2024

    Address, including zip code, and telephone number, including area code, of Registrant’s principal executive offices

     

     

    Hing C. Wong, Ph.D.

    Chief Executive Officer

    HCW Biologics Inc.

    2929 N Commerce Parkway

    Miramar, FL 33025

    (954) 842-2024

    Name, Address Including Zip Code, and Telephone Number, Including Area Code, of Agent for Service

     

     

    With a copy to:

     

    James Groth

    Clark Hill PLC

    130 E. Randolph St., Ste. 3900

    Chicago, IL 60601

    (312) 985-5900

     

    Randolf Katz

    Clark Hill PLC

    555 S. Flower St., 24 Floor

    Los Angeles, CA 90071

    (213) 891-9100

    Barry I. Grossman, Esq.

    Matthew Bernstein, Esq.

    Justin Grossman, Esq.

    Ellenoff Grossman & Schole LLP

    1345 Avenue of the Americas

    New York, New York 10105

    Tel: (212) 370-1300

     

     

    Approximate Date of Commencement of Proposed Sale to the Public: As soon as practicable after this registration statement becomes effective.

    If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, check the following box.  ☑

    If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.  ☐

    If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering.  ☐

    If this Form is a post-effective amendment filed pursuant to Rule 462(d) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. ☐

    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

     

    Large accelerated filer   ☐    Accelerated filer   ☐
    Non-accelerated filer   ☑    Smaller reporting company   ☑
         Emerging growth company   ☑

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.  ☐

     

     

    The registrant hereby amends this registration statement on such date or dates as may be necessary to delay its effective date until the registrant shall file a further amendment which specifically states that this registration statement shall thereafter become effective in accordance with Section 8(a) of the Securities Act or until the registration statement shall become effective on such date as the Securities and Exchange Commission, acting pursuant to Section 8(a) of the Securities Act, may determine.

     

     
     


    EXPLANATORY NOTE

    HCW Biologics Inc. is filing this Amendment No. 1 to its Registration Statement on Form S-1 (File No. 333-287136) as an exhibits-only filing. Accordingly, this Amendment consists only of the facing page, this explanatory note, Item 16(a) of Part II of the Registration Statement, the signature page to the Registration Statement and the filed exhibits. The remainder of the Registration Statement is unchanged and has therefore been omitted.


    PART II

    Item 16. Exhibits.

    EXHIBIT INDEX

     

             Incorporated by reference     Filed or
    furnished
    herewith
     

    Exhibit No.

      

    Exhibit title

      Form     File No.     Exhibit No.     Filing date        
    1.1    Form of Placement Agency Agreement*          
    3.1    Amended and Restated Certificate of Incorporation*     8-K       001-40591       3.1       07/26/2021    
    3.1a    Certificate of Amendment of Certificate of Incorporation, filed March 31, 2025.*     8-K       001-40591       3.1a       04/01/2025    
    3.1b    Certificate of Correction of the Certificate of Amendment of Certificate of Incorporation, filed April 1, 2025.*     8-K       001-40591       3.1b       04/01/2025    
    3.2    Amended and Restated Bylaws*     8-K       001-40591       3.2       07/26/2021    
    4.1    Specimen Stock Certificate*     S-1/A       333-256510       4.1       07/09/2021    
    4.2    Description of Securities*     10-K       001-40591       4.2       03/29/2022    
    4.3    Form of Common Stock Purchase Warrant between the Company and Holder*     8-K       001-40591       4.1       11/20/2024    
    4.4    Form of Pre-Funded Common Stock Purchase Warrant between the Company and Holder*     8-K       001-40591       4.2       11/20/2024    
    4.5    Form of Pre-Funded Common Stock Purchase Warrant*          
    4.6    Form of Common Stock Purchase Warrant*          
    4.7    Form of Warrant Agency Agreement*          
    5.1    Opinion of Clark Hill PLC             X  
    10.1    Form of Indemnification Agreement between HCW Biologics Inc. and each of its officers and directors.*     S-1/A       333-256510       10.1       07/09/2021    
    10.2+    2019 Equity Incentive Plan, as amended, and forms of agreement thereunder.*     S-1       333-256510       10.2       07/09/2021    
    10.3+    First Amendment to 2019 Equity Incentive Plan.*     S-1       333-256510       10.3       07/09/2021    
    10.4+    2021 Equity Incentive Plan and forms of agreement thereunder*     S-1       333-256510       10.4       07/09/2021    
    10.5+    Employment Agreement, dated July 6, 2021, between Peter Rhode and HCW Biologics Inc.*     S-1       333-256510       10.6       07/09/2021    
    10.6+    Employment Agreement, dated October 9, 2019, between Rebecca Byam and HCW Biologics Inc.     S-1       333-256510       10.7       07/09/2021    


            Incorporated by reference     Filed or
    furnished
    herewith
     

    Exhibit No.

     

    Exhibit title

      Form     File No.     Exhibit No.     Filing date        
    10.7+   Non-Employee Director Compensation Policy.*     S-1       333-256510       10.8       07/09/2021    
    10.8+   Employment Agreement, dated June 18, 2021, between Dr. Hing C. Wong and HCW Biologics Inc.*     S-1       333-256510       10.13       07/09/2021    
    10.9+   Executive Incentive Bonus Plan*     S-1       333-256510       10.11       07/09/2021    
    10.10†   Exclusive License Agreement, dated December 24, 2020, between HCW Biologics Inc. and Wugen, Inc.*     S-1       333-256510       10.10       07/09/2021    
    10.11†   Master Services Agreement, dated March 14, 2019, between HCW Biologics Inc. and EirGenix, Inc.*     S-1       333-256510       10.12       07/09/2021    
    10.12†#   Purchase and Sale Agreement, by and between HCW Biologics Inc. and Wai 3300 Corporate Way, LLC, dated May 27, 2022*     10-Q       001-40591       10.1       08/12/2022    
    10.13   Capital on Demand Sales Agreement, dated August  19, 2022, by and between HCW Biologics Inc. and Jones Trading Institutional Services LLC*     S-3       333-266991       1.2       08/19/2022    
    10.14   Loan Agreement by and between HCW Biologics Inc. and Cogent Bank, dated August 15, 2022*     10-Q       001-40591       10.1       11/07/2022    
    10.15   Mortgage and Security Agreement by and between HCW Biologics Inc. and Cogent Bank, dated August 15, 2022*     10-Q       001-40591       10.2       11/07/2022    
    10.16   Form of Subscription Agreement, dated February 20, 2024, by and between the Company and the Subscribers party thereto*     8-K       001-40591       10.1       02/22/2024    
    10.17*†#   Form of Senior Secured Note Purchase Agreement, dated March 28, 2024, by and between the Company and the Purchaser party thereto*     10-K       001-40591       10.17       04/01/2024    
    10.18*†#   Form of Senior Secured Promissory Note, dated March 28, 2024, by and between the Company and the Holder party thereof*     10-K       001-40591       10.18       04/01/2024    
    10.19*†#   Form of Pledge Agreement, dated March 28, 2024, by and between the Company, Escrow Agent and Noteholder party thereto*     10-K       001-40591       10.19       04/01/2024    
    10.20*†#   Form of Escrow Agreement, dated March 28, 2024, by and between the Company, Escrow Agent and Noteholder party thereto*     10-K       001-40591       10.20       04/01/2024    
    10.21   Senior Secured Note Purchase Agreement, dated March 28, 2024, by and between the Company and the Purchaser party thereto*     10-Q       001-40591       10.1       05/15/2024    


             Incorporated by reference     Filed or
    furnished
    herewith
     

    Exhibit No.

      

    Exhibit title

      Form     File No.     Exhibit No.     Filing date        
    10.22    Form of Subscription Agreement, dated February 20, 2024, by and between the Company and the Subscribers party thereto*     10-Q       001-40591       10.5       05/15/2024    
    10.23    Form of Amended and Restated Senior Secured Note Purchase Agreement, dated July  2, 2024, by and between the Company and the Purchaser party thereto*     10-Q       001-40591       10.1       08/14/2024    
    10.24    Form of Senior Secured Promissory Note by and between the Company and the Holder party thereof*     10-Q       001-40591       10.2       08/14/2024    
    10.25    Form of Amended and Restated Pledge Agreement, dated July  2, 2024, by and among the Company, Escrow Agent and Noteholder parties thereto*     10-Q       001-40591       10.3       08/14/2024    
    10.26    Form of Escrow Agreement, dated July 2, 2024, by and among the Company, Escrow Agent and Noteholder parties thereto*     10-Q       001-40591       10.4       08/14/2024    
    10.27    Form of First Amendment to the Amended and Restated Senior Secured Note Purchase Agreement, dated September  30, 2024, by and between the Company and Purchaser parties thereto*     10-Q       001-40591       10.5       11/14/2024    
    10.28    Settlement Agreement and Release, dated July  13, 2024, by and between the Company and Altor BioScience, LLC, NantCell, Inc., and ImmunityBio, Inc.*     10-Q       001-40591       10.6       11/14/2024    
    10.29    Placement Agency Agreement, dated November 18, 2024, between the Company and Maxim Group LLC.*     8-K       001-40591       4.1       11/20/2024    
    10.30    Securities Purchase Agreement, dated November 18, 2024, between the Company and Purchaser*     8-K       001-40591       4.1       11/20/2024    
    10.31    Equity Purchase Agreement, dated February 20, 2025, between the Company and Square Gate Master Fund—Series 4.*     8-K       001-40591       10.1       02/21/2025    
    10.32    Registration Rights Agreement, dated February 20, 2025, between the Company and Square Gate Master Fund—Series 4.*     8-K       001-40591       10.2       02/21/2025    
    10.33    Second Amendment to Amended and Restated Senior Secured Note Purchase Agreement and Related Agreements dated as of May 1, 2025.          
    10.34    Form of Unsecured Convertible Promissory Note dated May 5, 2025 by and between the Company and the Holder party thereto.*          


             Incorporated by reference     Filed or
    furnished
    herewith
     

    Exhibit No.

      

    Exhibit title

      Form     File No.     Exhibit No.     Filing date        
    10.35    Form of Securities Purchase Agreement*          
    10.36    Form of Lock-Up Agreement*          
    23.1a    Consent of Independent Registered Public Accounting Firm (Grant Thornton, Predecessor)*          
    23.1b    Consent of Independent Registered Public Accounting Firm (Crowe Successor)*          
    23.2    Opinion of Clark Hill PLC (included in Exhibit 5.1)             X  
    97.1    HCW Biologics Inc. Compensation Recovery Policy*     10-K       001-40591       97.1       04/01/2024    
    99.1    Audit Committee Charter of the Registrant*          
    99.2    Compensation Committee Charter of the Registrant*          
    99.3    HCW Biologics Inc. Related Party Transaction Policy*          
    107    Filing Fees*          

     

    *

    Previously filed


    SIGNATURES

    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this registration statement on Form S-1 to be signed on its behalf by the undersigned, in the city of Miramar, State of Florida, on May 13, 2025.

     

     

    HCW BIOLOGICS INC.

    By:   /s/ Hing C. Wong
    Name:   Hing C. Wong
    Title:   Founder & Chief Executive Officer

    Pursuant to the requirements of the Securities Exchange Act of 1933, the registrant has duly caused this registration statement on Form S-1 to be signed on its behalf by the undersigned, thereunto duly authorized.

     

    Signature

      

    Title

     

    Date

    /s/ Scott T. Garrett

    Scott T. Garrett

      

    Chairman of the Board of Directors

      May 13, 2025

    /s/ Rebecca Byam

    Rebecca Byam

      

    Chief Financial Officer

      May 13, 2025

    /s/ Hing C. Wong

    Hing C. Wong

      

    Chief Executive Officer

      May 13, 2025

    /s/ Rick S. Greene

    Rick S. Greene

      

    Director

      May 13, 2025

    /s/ Lisa M. Giles

    Lisa M. Giles

      

    Director

      May 13, 2025

    /s/ Gary M. Winer

    Gary M. Winer

      

    Director

      May 13, 2025

     

    By:   /s/ Hing C. Wong
      Hing C. Wong, Attorney-in-Fact
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