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    Amendment: SEC Form SC 13G/A filed by Tarsus Pharmaceuticals Inc.

    11/6/24 10:26:57 AM ET
    $TARS
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $TARS alert in real time by email
    SC 13G/A 1 d898648dsc13ga.htm SC 13G/A SC 13G/A

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    WASHINGTON, DC 20549

     

     

    SCHEDULE 13G

    UNDER THE SECURITIES EXCHANGE ACT OF 1934

    (Amendment No. 2)*

     

     

    Tarsus Pharmaceuticals, Inc.

    (Name of Issuer)

    Common Stock

    (Title of Class of Securities)

    87650L 103

    (CUSIP Number)

    September 30, 2024

    (Date of Event Which Requires Filing of this Statement)

     

     

    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     

      ☐

    Rule 13d-1(b)

     

      ☒

    Rule 13d-1(c)

     

      ☐

    Rule 13d-1(d)

     

    *

    The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

    The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

     

     

     


    CUSIP No. 87650L 103

     

     1.   

     Names of Reporting Persons

     

     Frazier Life Sciences IX, L.P.

     2.  

     Check the Appropriate Box if a Member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3.  

     SEC USE ONLY

     

     4.  

     Citizenship or Place of Organization

     

     Delaware

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5.   

     Sole Voting Power

     

     0 shares

       6.  

     Shared Voting Power

     

     1,587,527 shares (1)

       7.  

     Sole Dispositive Power

     

     0 shares

       8.  

     Shared Dispositive Power

     

     1,587,527 shares (1)

     9.   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     1,587,527 shares (1)

    10.  

     Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

     

     ☐

    11.  

     Percent of Class Represented by Amount in Row 9

     

     4.2% (2)

    12.  

     Type of Reporting Person (see instructions)

     

     PN

     

    (1)

    Consists of 1,587,527 shares of Common Stock held directly by Frazier Life Sciences IX, L.P. FHMLS IX, L.P. is the general partner of Frazier Life Sciences IX, L.P. and FHMLS IX, L.L.C. is the general partner of FHMLS IX, L.P. Patrick Heron and James Topper are the members of FHMLS IX, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences IX, L.P.

    (2)

    Based on 38,041,737 shares of Common Stock outstanding on August 2, 2024 as set forth in the Issuer’s Form 10-Q filed with the SEC on August 8, 2024.


    CUSIP No. 87650L 103

     

     1.   

     Names of Reporting Persons

     

     FHMLS IX, L.P.

     2.  

     Check the Appropriate Box if a Member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3.  

     SEC USE ONLY

     

     4.  

     Citizenship or Place of Organization

     

     Delaware

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5.   

     Sole Voting Power

     

     0 shares

       6.  

     Shared Voting Power

     

     1,587,527 shares (1)

       7.  

     Sole Dispositive Power

     

     0 shares

       8.  

     Shared Dispositive Power

     

     1,587,527 shares (1)

     9.   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     1,587,527 shares (1)

    10.  

     Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

     

     ☐

    11.  

     Percent of Class Represented by Amount in Row 9

     

     4.2% (2)

    12.  

     Type of Reporting Person (see instructions)

     

     PN

     

    (1)

    Consists of 1,587,527 shares of Common Stock held directly by Frazier Life Sciences IX, L.P. FHMLS IX, L.P. is the general partner of Frazier Life Sciences IX, L.P. and FHMLS IX, L.L.C. is the general partner of FHMLS IX, L.P. Patrick Heron and James Topper are the members of FHMLS IX, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences IX, L.P.

    (2)

    Based on 38,041,737 shares of Common Stock outstanding on August 2, 2024 as set forth in the Issuer’s Form 10-Q filed with the SEC on August 8, 2024.


    CUSIP No. 87650L 103

     

     1.   

     Names of Reporting Persons

     

     FHMLS IX, L.L.C.

     2.  

     Check the Appropriate Box if a Member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3.  

     SEC USE ONLY

     

     4.  

     Citizenship or Place of Organization

     

     Delaware

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5.   

     Sole Voting Power

     

     0 shares

       6.  

     Shared Voting Power

     

     1,587,527 shares (1)

       7.  

     Sole Dispositive Power

     

     0 shares

       8.  

     Shared Dispositive Power

     

     1,587,527 shares (1)

     9.   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     1,587,527 shares (1)

    10.  

     Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

     

     ☐

    11.  

     Percent of Class Represented by Amount in Row 9

     

     4.2% (2)

    12.  

     Type of Reporting Person (see instructions)

     

     OO

     

    (1)

    Consists of 1,587,527 shares of Common Stock held directly by Frazier Life Sciences IX, L.P. FHMLS IX, L.P. is the general partner of Frazier Life Sciences IX, L.P. and FHMLS IX, L.L.C. is the general partner of FHMLS IX, L.P. Patrick Heron and James Topper are the members of FHMLS IX, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences IX, L.P.

    (2)

    Based on 38,041,737 shares of Common Stock outstanding on August 2, 2024 as set forth in the Issuer’s Form 10-Q filed with the SEC on August 8, 2024.


    CUSIP No. 87650L 103

     

     1.   

     Names of Reporting Persons

     

     James Topper

     2.  

     Check the Appropriate Box if a Member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3.  

     SEC USE ONLY

     

     4.  

     Citizenship or Place of Organization

     

     United States Citizen

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5.   

     Sole Voting Power

     

     0 shares

       6.  

     Shared Voting Power

     

     1,587,527 shares (1)

       7.  

     Sole Dispositive Power

     

     0 shares

       8.  

     Shared Dispositive Power

     

     1,587,527 shares (1)

     9.   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     1,587,527 shares (1)

    10.  

     Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

     

     ☐

    11.  

     Percent of Class Represented by Amount in Row 9

     

     4.2% (2)

    12.  

     Type of Reporting Person (see instructions)

     

     IN

     

    (1)

    Consists of 1,587,527 shares of Common Stock held directly by Frazier Life Sciences IX, L.P. FHMLS IX, L.P. is the general partner of Frazier Life Sciences IX, L.P. and FHMLS IX, L.L.C. is the general partner of FHMLS IX, L.P. Patrick Heron and James Topper are the members of FHMLS IX, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences IX, L.P.

    (2)

    Based on 38,041,737 shares of Common Stock outstanding on August 2, 2024 as set forth in the Issuer’s Form 10-Q filed with the SEC on August 8, 2024.


    CUSIP No. 87650L 103

     

     1.   

     Names of Reporting Persons

     

     Patrick Heron

     2.  

     Check the Appropriate Box if a Member of a Group (see instructions)

     (a) ☐  (b) ☒

     

     3.  

     SEC USE ONLY

     

     4.  

     Citizenship or Place of Organization

     

     United States Citizen

    Number of

    Shares  Beneficially 

    Owned by

    Each

    Reporting

    Person

    With:

       5.   

     Sole Voting Power

     

     0 shares

       6.  

     Shared Voting Power

     

     1,587,527 shares (1)

       7.  

     Sole Dispositive Power

     

     0 shares

       8.  

     Shared Dispositive Power

     

     1,587,527 shares (1)

     9.   

     Aggregate Amount Beneficially Owned by Each Reporting Person

     

     1,587,527 shares (1)

    10.  

     Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)

     

     ☐

    11.  

     Percent of Class Represented by Amount in Row 9

     

     4.2% (2)

    12.  

     Type of Reporting Person (see instructions)

     

     IN

     

    (1)

    Consists of 1,587,527 shares of Common Stock held directly by Frazier Life Sciences IX, L.P. FHMLS IX, L.P. is the general partner of Frazier Life Sciences IX, L.P. and FHMLS IX, L.L.C. is the general partner of FHMLS IX, L.P. Patrick Heron and James Topper are the members of FHMLS IX, L.L.C. and therefore share voting and investment power over the shares held by Frazier Life Sciences IX, L.P.

    (2)

    Based on 38,041,737 shares of Common Stock outstanding on August 2, 2024 as set forth in the Issuer’s Form 10-Q filed with the SEC on August 8, 2024.


    Item 1(a).    Name of Issuer: Tarsus Pharmaceuticals, Inc.
    Item 1(b).    Address of Issuer’s Principal Executive Offices: 15440 Laguna Canyon Road, Suite 160, Irvine, CA 92618
    Item 2(a).   

    Name of Person Filing:

     

    The entities and persons filing this statement (collectively, the “Reporting Persons”) are:

     

    Frazier Life Sciences IX, L.P. (“FLS IX”)

    FHMLS IX, L.P.

    FHMLS IX, L.L.C.

    James Topper (“Topper”)

    Patrick Heron (“Heron” and together with Topper, the “Members”)

    Item 2(b).   

    Address of Principal Business Office or, if none, Residence:

     

    The address and principal business office of the Reporting Persons is:

     

    c/o Frazier Life Sciences Management, L.P.

    1001 Page Mill Rd, Building 4, Suite B

    Palo Alto, CA 94304

    Item 2(c).   

    Citizenship:

         
      

    Entities:

      

    FLS IX

    FHMLS IX, L.P.

    FHMLS IX, L.L.C

     

      

    -   Delaware, U.S.A.

    -   Delaware, U.S.A.

    -   Delaware, U.S.A.

     

       Individuals:   

    Topper

    Heron

      

    -   United States Citizen

    -   United States Citizen

    Item 2(d).    Title of Class of Securities: Common Stock
    Item 2(e).    CUSIP Number: 87650L 103
    Item 3.    If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:

    (a)

      

    ☐   Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o);

    (b)

      

    ☐   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);

    (c)

      

    ☐   Insurance company as defined in section 3(a)19) of the Act (15 U.S.C. 78c);

    (d)

      

    ☐   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);

    (e)

      

    ☐   An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

    (f)

      

    ☐   An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);

    (g)

      

    ☐   A parent holding company or control person in accordance with §240.13d-1(b)(1)(ii)(G);

    (h)

      

    ☐   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

    (i)

      

    ☐   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

    (j)

      

    ☐   A non-U.S. institution in accordance with §240.13d–1(b)(1)(ii)(J);

    (k)

      

    ☐   Group, in accordance with §240.13d–1(b)(1)(ii)(K).

       If filing as a non-U.S. institution in accordance with §240.13d–1(b)(1)(ii)(J), please specify the type of institution: ____
    Item 4.    Ownership

    Provide the following information regarding the aggregate number and percentage of the class of securities of the Issuer identified in Item 1.


      (a)

    Amount Beneficially Owned: See Row 9 of cover page for each Reporting Person.

     

      (b)

    Percent of Class: See Row 11 of cover page for each Reporting Person

     

      (c)

    Number of shares as to which the person has:

     

      (i)

    Sole power to vote or to direct the vote: See Row 5 of cover page for each Reporting Person.

     

      (ii)

    Shared power to vote or to direct the vote: See Row 6 of cover page for each Reporting Person.

     

      (iii)

    Sole power to dispose or to direct the disposition of: See Row 7 of cover page for each Reporting Person.

     

      (iv)

    Shared power to dispose or to direct the disposition of: See Row 8 of cover page for each Reporting Person.

     

    Item 5.

    Ownership of 5 Percent or Less of a Class

    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following ☒.

     

    Item 6.

    Ownership of More than 5 Percent on Behalf of Another Person

    Not applicable.

     

    Item 7.

    Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.

    Not applicable.

     

    Item 8.

    Identification and Classification of Members of the Group

    Each member of the group is identified on Exhibit A to this Schedule 13G.

     

    Item 9.

    Notice of Dissolution of a Group

    Not applicable.

     

    Item 10.

    Certification

    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.


    SIGNATURE

    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     

    Date: November 6, 2024       FRAZIER LIFE SCIENCES IX, L.P.
        By FHMLS IX, L.P., its general partner
        By FHMLS IX, L.L.C., its general partner
            By:  

    /s/ Steve R. Bailey

          Steve R. Bailey, Chief Financial Officer
    Date: November 6, 2024       FHMLS IX, L.P.
            By   FHMLS IX, L.L.C., its general partner
        By:  

    /s/ Steve R. Bailey

          Steve R. Bailey, Chief Financial Officer
    Date: November 6, 2024       FHMLS IX, L.L.C.
            By:  

    /s/ Steve R. Bailey

          Steve R. Bailey, Chief Financial Officer
    Date: November 6, 2024       By:  

    *

          James Topper
    Date: November 6, 2024       By:  

    *

          Patrick Heron
    Date: November 6, 2024     *By:  

    /s/ Steve R. Bailey

          Steve R. Bailey, as Attorney-in-Fact

     

    *

    This Schedule 13G was executed by Steve R. Bailey on behalf of the individuals listed above pursuant to a Power of Attorney, a copy of which was filed with the SEC on July 31, 2017.

     

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      11/14/24 4:35:55 PM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Amendment: SEC Form SC 13G/A filed by Tarsus Pharmaceuticals Inc.

      SC 13G/A - Tarsus Pharmaceuticals, Inc. (0001819790) (Subject)

      11/14/24 3:05:35 PM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $TARS
    Insider Trading

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    • President/CEO and Board Chair Azamian Bobak R. sold $300,000 worth of shares (6,000 units at $50.00) (SEC Form 4)

      4 - Tarsus Pharmaceuticals, Inc. (0001819790) (Issuer)

      3/26/25 4:47:19 PM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Chief Commercial Officer Mottiwala Aziz sold $505,856 worth of shares (10,565 units at $47.88), decreasing direct ownership by 14% to 65,057 units (SEC Form 4)

      4 - Tarsus Pharmaceuticals, Inc. (0001819790) (Issuer)

      3/20/25 9:49:54 PM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Chief Operating Officer Neervannan Seshadri sold $363,142 worth of shares (7,583 units at $47.89), decreasing direct ownership by 9% to 79,682 units (SEC Form 4)

      4 - Tarsus Pharmaceuticals, Inc. (0001819790) (Issuer)

      3/20/25 9:49:35 PM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $TARS
    Financials

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    • Tarsus Reports First Quarter 2025 Financial Results and Recent Business Achievements

      Generated $78.3 million in net product sales of XDEMVY®, an increase of 217% year over year and 18% over Q4 2024, and dispensed approximately 72,000 bottles to patients Strengthened financial position with approximately $135 million raised in public equity offering; cash, cash equivalents and marketable securities of approximately $408 million as of March 31, 2025 On-track to initiate a Phase 2 trial of TP-04 (lotilaner ophthalmic gel) for the potential treatment of Ocular Rosacea in H2 2025 Management to host conference call today, May 1, 2025, at 1:30 p.m. P.T. / 4:30 p.m. E.T. IRVINE, Calif., May 01, 2025 (GLOBE NEWSWIRE) -- Tarsus Pharmaceuticals, Inc. (NASDAQ:TARS), today announce

      5/1/25 4:05:00 PM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Tarsus to Report First Quarter 2025 Financial Results on Thursday, May 1, 2025

      IRVINE, Calif., April 24, 2025 (GLOBE NEWSWIRE) -- Tarsus Pharmaceuticals, Inc. (NASDAQ:TARS), today announced that it will host a live webcast at 1:30 p.m. PT / 4:30 p.m. ET on Thursday, May 1, 2025, to report its first quarter 2025 financial results and provide a corporate update. Participants may access the webcast here. A recorded version of the call will be available on the website shortly after the completion of the webcast and will be archived there for approximately 90 days. About Tarsus Pharmaceuticals, Inc.Tarsus Pharmaceuticals, Inc. applies proven science and new technology to revolutionize treatment for patients, starting with eye care. Tarsus is advancing its pipeline to ad

      4/24/25 5:00:00 PM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Tarsus Reports Strong Fourth Quarter and Full-Year 2024 Financial Results and Recent Business Achievements

      Generated fourth quarter and full-year 2024 net product sales of XDEMVY® of $66.4 million and $180.1 million, respectively, during the first full year of launch Presented groundbreaking XDEMVY data; first pharmacologic treatment to demonstrate functional improvements in Meibomian Gland Disease and patient symptoms in Demodex blepharitis patients Continued advancing TP-04 (lotilaner ophthalmic gel) for the potential treatment of Ocular Rosacea, the next category-creating opportunity in eye care Management to host conference call today, February 25, 2025, at 5 a.m. PT / 8 a.m. ET IRVINE, Calif., Feb. 25, 2025 (GLOBE NEWSWIRE) -- Tarsus Pharmaceuticals, Inc. (NASDAQ:TARS), today announced

      2/25/25 7:00:00 AM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $TARS
    Leadership Updates

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    • Tarsus Welcomes Kate Goodrich, M.D., MHS, to its Board of Directors

      Humana CMO brings more than two decades of experience driving innovative, value-based initiatives designed to improve patient outcomes IRVINE, Calif., Nov. 13, 2024 (GLOBE NEWSWIRE) -- Tarsus Pharmaceuticals, Inc. (NASDAQ:TARS), whose mission is to focus on unmet needs and apply proven science and new technology to revolutionize treatment for patients, starting with eye care, today announced the appointment of Katherine H. (Kate) Goodrich, M.D., MHS, Chief Medical Officer of Humana Inc., to its Board of Directors. Dr. Goodrich is a seasoned executive and practicing physician who has dedicated her career to championing innovative healthcare initiatives designed to improve healthcare access

      11/13/24 8:30:00 AM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Tarsus Appoints Elizabeth Yeu, M.D., as Chief Medical Officer

      IRVINE, Calif., Nov. 05, 2024 (GLOBE NEWSWIRE) -- Tarsus Pharmaceuticals, Inc. (NASDAQ:TARS), whose mission is to address unmet medical needs and apply proven science and new technology to revolutionize treatment for patients, starting with eye care, today announced the appointment of Elizabeth Yeu, M.D., as Chief Medical Officer, effective November 4, 2024. A distinguished ophthalmologist with more than two decades of clinical experience and leadership, Dr. Yeu has served as Tarsus' Chief Medical Advisor since 2020 and as a Board member since 2021. In this new role, she will be responsible for leading the strategy, direction and execution of the Company's new Medical Organization compris

      11/5/24 8:30:00 AM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Tarsus Appoints Jeff Farrow as Chief Financial Officer and Chief Strategy Officer

      IRVINE, Calif., April 24, 2023 (GLOBE NEWSWIRE) -- Tarsus Pharmaceuticals, Inc. (NASDAQ:TARS), whose mission is to focus on unmet needs and apply proven science and new technology to revolutionize treatment for patients, starting with eye care, today announced the appointment of Jeff Farrow as Chief Financial Officer and Chief Strategy Officer, effective immediately. Mr. Farrow succeeds Leo Greenstein who served as CFO since 2020 and will be leaving Tarsus to pursue other professional interests. Mr. Farrow is a seasoned finance and corporate strategy executive with more than two decades of experience successfully leading teams in the life science industry, including several publicly tra

      4/24/23 8:30:00 AM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $TARS
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

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    • Goldberg Andrew D. bought $18,960 worth of shares (1,000 units at $18.96), increasing direct ownership by 50% to 3,000 units (SEC Form 4)

      4 - Tarsus Pharmaceuticals, Inc. (0001819790) (Issuer)

      12/19/23 6:30:59 PM ET
      $TARS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care