• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
PublishGo to AppAI Superconnector
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEWLLM Arena
    Legal
    Terms of usePrivacy policyCookie policy

    Amendment: SEC Form SCHEDULE 13D/A filed by Humacyte Inc.

    10/16/25 5:25:05 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $HUMA alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13D

    Under the Securities Exchange Act of 1934

    (Amendment No. 005)


    HUMACYTE, INC.

    (Name of Issuer)


    Common Stock, par value $0.0001 per share

    (Title of Class of Securities)


    020751103

    (CUSIP Number)


    Robert A. Grauman
    145 West 86 Street,
    New York, NY, 10024
    646 202-2932


    Thomas D. Brouillard
    Fresenius Medical Care Holdings, Inc., 920 Winter Street
    Waltham, MA, 02451-1547
    781 699 9000


    Christof Koester
    Fresenius Medical Care AG, Else-Kroner Strasse 1
    Bad Homburg, 2M, 61352
    011 49 6172 609 0

    (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)
    10/08/2025

    (Date of Event Which Requires Filing of This Statement)


    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. Checkbox not checked

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).






    SCHEDULE 13D

    CUSIP No.
    020751103


    1 Name of reporting person

    Fresenius Medical Care AG
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    AF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    GERMANY
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    0.00
    8Shared Voting Power

    18,312,735.00
    9Sole Dispositive Power

    0.00
    10Shared Dispositive Power

    18,312,735.00
    11Aggregate amount beneficially owned by each reporting person

    18,312,735.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    9.9 %
    14Type of Reporting Person (See Instructions)

    CO



    SCHEDULE 13D

    Item 1.Security and Issuer
    (a)Title of Class of Securities:

    Common Stock, par value $0.0001 per share
    (b)Name of Issuer:

    HUMACYTE, INC.
    (c)Address of Issuer's Principal Executive Offices:

    2525 East North Carolina Highway 54, Durham, NORTH CAROLINA , 27713.
    Item 1 Comment:
    This Amendment No. 5 amends certain items of the Schedule 13D originally filed on September 2, 2021, as previously amended by Amendment No. 1 filed on December 1, 2023, by Amendment No. 2 filed March 7, 2024, by Amendment No 3 filed on November 18, 2024 and by Amendment No. 4 filed May 22, 2025 (as so amended, the "Schedule 13D") by Fresenius Medical Care Holdings, Inc., a New York Corporation ("FMCH") and Fresenius Medical Care AG a German stock corporation ("FME AG") with respect to the common stock, par value $0.0001 per share (the "Common Stock") of Humacyte, Inc., a Delaware corporation, formerly known as Alpha Healthcare Acquisition Corp. (the "Issuer" or "Humacyte"). This Amendment No. 5 is being filed solely by FME AG. Capitalized terms not otherwise defined herein have the meanings set forth in the Schedule 13D. Except as provided herein, this Amendment No. 5 does not modify any of the information previously reported on the Schedule 13D.
    Item 2.Identity and Background
    (a)
    Item 2 of the Schedule 13D is hereby amended as set forth below: On October 1, 2025, FME AG announced the appointment of Joseph E. (Joe) Turk as a member of the Management Board, effective January 1, 2026. Mr. Turk will serve as Chief Executive Officer of the Care Enablement segment, succeeding Dr. Katarzyna Mazur-Hofsaess. Mr., Turk is a citizen of the United States.
    Item 5.Interest in Securities of the Issuer
    (a)
    On the date of this Schedule 13D (Amendment No. 5), FMCH is the beneficial owner of 18,312,735 shares of the Issuer's Common Stock, constituting approximately 9.9% of the Issuer's outstanding voting shares (calculated with reference to 184,778,911 shares outstanding as of October 8, 2025, being the number of shares of the Issuer outstanding after giving effect to the offering made by the Issuer in its Prospectus Supplement dated October 6, 2025). All such 18,312,735 Shares are issued and outstanding and owned directly by FMCH. Such 18,312,735 shares of Common Stock exclude any additional contingent shares of Common Stock that may be issued pursuant to the terms of the Business Combination described in the initial Schedule 13D, and FME AG and FMCH disclaim any present beneficial ownership of any such additional shares.
    (b)
    As the record owner of the 18,312,735 shares of Common Stock reported in this Schedule 13D (Amendment No 5), FMCH possesses voting and dispositive power over such shares. FME AG is the indirect sole shareholder of FMCH and may be deemed to be a beneficial owner of such shares.
    (c)
    The decrease in the percentage beneficial ownership reported herein from 11.8%, as reported in Schedule 13D (Amendment No. 4) to 9.9%, as reported in this Schedule 13D (Amendment No. 5) results solely from an increase in the number of outstanding shares of the Issuer's Common Stock subsequent to the filing of Amendment No. 4 to this Schedule 13D. Neither FME AG nor FMCH has disposed of or acquired any shares of the Issuer's Common Stock subsequent to the filing of their initial Schedule 13D in September 2021.

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Fresenius Medical Care AG
     
    Signature:/s/ i.V. Philipp Bosch
    Name/Title:i.V. Philipp Bosch, Senior Vice President, General Counsel Global Medical Technology (Care Enablement)
    Date:10/16/2025
     
    Signature:/s/ Christof Koester
    Name/Title:Christof Koester, Prokurist, Senior Vice President, General Counsel--Corporate Governance
    Date:10/16/2025
    Get the next $HUMA alert in real time by email

    Crush Q3 2025 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $HUMA

    DatePrice TargetRatingAnalyst
    8/27/2025$3.50Overweight
    Barclays
    5/14/2025$4.00Buy
    H.C. Wainwright
    12/20/2024$12.00 → $15.00Buy
    H.C. Wainwright
    12/11/2023$6.00Buy
    H.C. Wainwright
    8/14/2023$2.75 → $3.50Underweight → Neutral
    Piper Sandler
    6/22/2023$6.00Overweight
    Cantor Fitzgerald
    5/16/2022$10.00 → $4.00Overweight → Underweight
    Piper Sandler
    10/29/2021$17.00Outperform
    Cowen & Co.
    More analyst ratings

    $HUMA
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    Humacyte Announces Pricing of $60.0 Million Oversubscribed Registered Direct Offering

    DURHAM, N.C., Oct. 07, 2025 (GLOBE NEWSWIRE) -- Humacyte, Inc. (NASDAQ:HUMA), a commercial-stage biotechnology platform company developing universally implantable, bioengineered human tissues at commercial scale, today announced that it entered into a securities purchase agreement with certain fundamental institutional investors to purchase approximately $60.0 million worth of its common stock and warrants in an oversubscribed registered direct offering. Under the terms of the securities purchase agreement, the Company has agreed to sell 28,436,018 shares of its common stock and warrants to purchase 28,436,018 shares of common stock. The warrants will become exercisable 180 days following

    10/7/25 9:00:00 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Humacyte Announces Publication of Long-Term Results for Ukrainian Patients Treated in Real-World Combat Setting with Symvess™

    - Results published in Oxford Academic's Military Medicine Journal - - After up to 18 months of follow-up patients were observed to have zero infections, amputations or deaths and a high rate of patency - DURHAM, N.C., Oct. 06, 2025 (GLOBE NEWSWIRE) -- Humacyte, Inc. (NASDAQ:HUMA), a commercial-stage biotechnology platform company developing universally implantable, bioengineered human tissues at commercial scale, today announced the publication in Oxford Academic's Military Medicine of positive long-term results from its humanitarian program using Symvess to treat wartime vascular trauma injuries in Ukraine. The publication, titled "Evaluating the Safety and Efficacy of Humacyte Acellu

    10/6/25 8:00:00 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Humacyte Announces Expansion of Intellectual Property for Pipeline Products with Granting of New U.S. Patent for Bioengineered Esophagus

    – Patent covers esophagus produced using Humacyte's proprietary bioengineered regenerative tissue platform, designed for implant in patients with damaged esophagus – – Patent provides coverage into 2041 for the composition of novel bioengineered esophagus – DURHAM, N.C., Sept. 29, 2025 (GLOBE NEWSWIRE) -- Humacyte, Inc. (NASDAQ: HUMA), a commercial-stage biotechnology platform company developing universally implantable, bioengineered human tissues at commercial scale, today announced the allowance of a U.S. Patent covering the composition of a bioengineered esophagus that can be produced using the Company's proprietary regenerative tissue engineering platform. The patent, titled "Tubular

    9/29/25 8:00:00 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $HUMA
    SEC Filings

    View All

    Amendment: SEC Form SCHEDULE 13D/A filed by Humacyte Inc.

    SCHEDULE 13D/A - Humacyte, Inc. (0001818382) (Subject)

    10/16/25 5:25:05 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Humacyte Inc. filed SEC Form 8-K: Entry into a Material Definitive Agreement, Regulation FD Disclosure, Financial Statements and Exhibits

    8-K - Humacyte, Inc. (0001818382) (Filer)

    10/7/25 5:31:23 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 424B3 filed by Humacyte Inc.

    424B3 - Humacyte, Inc. (0001818382) (Filer)

    10/7/25 9:00:47 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $HUMA
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    View All

    Chief Commercial Officer Scheessele William John bought $9,999 worth of shares (6,493 units at $1.54), increasing direct ownership by 42% to 22,018 units (SEC Form 4)

    4 - Humacyte, Inc. (0001818382) (Issuer)

    4/15/25 4:03:35 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    CFO and Chief Corp. Deve. Off. Sander Dale A. bought $30,600 worth of shares (20,000 units at $1.53) (SEC Form 4)

    4 - Humacyte, Inc. (0001818382) (Issuer)

    4/14/25 9:00:23 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Chief Medical Officer Parikh Shamik J bought $11,625 worth of shares (7,500 units at $1.55) (SEC Form 4)

    4 - Humacyte, Inc. (0001818382) (Issuer)

    4/14/25 9:00:12 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $HUMA
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    Director Dougan Brady W sold $3,733,191 worth of shares (2,241,045 units at $1.67) (SEC Form 4)

    4 - Humacyte, Inc. (0001818382) (Issuer)

    8/20/25 7:30:47 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    President, CEO and Director Niklason Laura E sold $3,733,191 worth of shares (2,241,045 units at $1.67) (SEC Form 4)

    4 - Humacyte, Inc. (0001818382) (Issuer)

    8/20/25 7:29:04 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 4 filed by Director Pope Todd

    4 - Humacyte, Inc. (0001818382) (Issuer)

    6/16/25 4:32:48 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $HUMA
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Barclays initiated coverage on Humacyte with a new price target

    Barclays initiated coverage of Humacyte with a rating of Overweight and set a new price target of $3.50

    8/27/25 8:22:05 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    H.C. Wainwright resumed coverage on Humacyte with a new price target

    H.C. Wainwright resumed coverage of Humacyte with a rating of Buy and set a new price target of $4.00

    5/14/25 11:33:51 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    H.C. Wainwright reiterated coverage on Humacyte with a new price target

    H.C. Wainwright reiterated coverage of Humacyte with a rating of Buy and set a new price target of $15.00 from $12.00 previously

    12/20/24 8:28:06 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $HUMA
    Leadership Updates

    Live Leadership Updates

    View All

    Dr. Juliana Blum Joins BioAesthetics as CEO

    BioAesthetics Corporation announced today the appointment of Juliana Blum, PhD as its new Chief Executive Officer, effective August 12, 2024. Dr. Sandra Coufal, MD, Director of BioAesthetics and CEO of Toragen, Inc. said, "This is an important milestone for BioAesthetics. During the development of every successful biotech company, there comes a time when the founding CEO transitions to a different role and a new CEO with different skill sets is needed for product advancement and commercialization. Dr. Blum's experience with novel products as co-founder of Humacyte will help guide further progress at BioAesthetics." Dr. Blum joins BioAesthetics following her 20 years spent as Co-founder

    8/26/24 2:00:00 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Humacyte Expands Board of Directors with Appointment of Diane Seimetz, Ph.D.

    DURHAM, N.C., June 27, 2022 (GLOBE NEWSWIRE) -- Humacyte, Inc. (NASDAQ:HUMA), a clinical-stage biotechnology platform company developing universally implantable bioengineered human tissue at commercial scale, today announced the appointment of Diane Seimetz, Ph.D., to its board of directors. "Diane is an innovator and strategist with extensive experience in the biopharmaceutical industry, and we are delighted to welcome her to the Humacyte board," said Kathleen Sebelius, Chair of Humacyte's board of directors. "Her expertise in guiding companies with innovative products to the market will be invaluable as Humacyte moves toward commercialization of the Human Acellular VesselTM (HAV). We al

    6/27/22 7:30:00 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Humacyte Expands Leadership Team with Appointment of Shamik Parikh, M.D., as Chief Medical Officer

    --Seasoned physician, scientist and life science executive brings expertise in clinical research and development across product life cycle-- --Key appointment as Humacyte advances HAV through multiple late-stage clinical trials in initial vascular applications-- DURHAM, N.C., April 05, 2022 (GLOBE NEWSWIRE) -- Humacyte, Inc. (NASDAQ:HUMA), a clinical-stage biotechnology platform company developing universally implantable bioengineered human tissue at commercial scale, today announced the appointment of Shamik J. Parikh, M.D., as Chief Medical Officer. In this role, Dr. Parikh will lead the company's global clinical development strategy, including oversight of the preclinical and clinical

    4/5/22 8:00:00 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $HUMA
    Financials

    Live finance-specific insights

    View All

    Humacyte to Present Second Quarter Financial Results and Provide Corporate Update on August 11, 2025

    DURHAM, N.C., Aug. 07, 2025 (GLOBE NEWSWIRE) -- Humacyte, Inc. (NASDAQ:HUMA), a clinical-stage biotechnology platform company developing universally implantable, bioengineered human tissue at commercial scale, will release its financial results for the quarter ended June 30, 2025, on Monday, August 11, 2025. Management will host a webcast and conference call at 8:00 a.m. ET to provide a corporate and financial update. Title:Humacyte Second Quarter 2025 Financial Results and Corporate UpdateDate:August 11, 2025Time:8:00 AM Eastern TimeConference Call Details:1-877-704-4453 (U.S. Investors Dial)1-201-389-0920 (International Investors Dial)13754596 (Conference ID)Call meTM Feature: Click Here

    8/7/25 8:00:00 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Humacyte to Present First Quarter Financial Results and Provide Corporate Update on May 13, 2025

    DURHAM, N.C., May 09, 2025 (GLOBE NEWSWIRE) -- Humacyte, Inc. (NASDAQ:HUMA), a clinical-stage biotechnology platform company developing universally implantable, bioengineered human tissue at commercial scale, will release its financial results for the quarter ended March 31, 2025, on Tuesday, May 13, 2025. Management will host a webcast and conference call at 8:30 a.m. ET to provide a corporate and financial update. Title:Humacyte First Quarter 2025 Financial Results and Corporate UpdateDate:May 13, 2025Time:8:30 AM Eastern TimeConference Call Details:1-877-704-4453 (U.S. Investors Dial)1-201-389-0920 (International Investors Dial)13753487 (Conference ID)Call meTM Feature: Click HereWebc

    5/9/25 8:00:00 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Humacyte to Present Fourth Quarter and Full Year Financial Results and Provide Corporate Update on March 28, 2025

    DURHAM, N.C., March 26, 2025 (GLOBE NEWSWIRE) -- Humacyte, Inc. (NASDAQ:HUMA), a clinical-stage biotechnology platform company developing universally implantable, bioengineered human tissue at commercial scale, will release its financial results for the fourth quarter and year ended December 31, 2024, on Friday, March 28, 2025. Management will host a webcast and conference call at 8:30 a.m. ET. Title:Humacyte Fourth Quarter and Full Year 2024 Financial Results and Corporate UpdateDate:March 28, 2025Time:8:30 AM Eastern TimeConference Call Details:1-877-704-4453 (U.S. Investors Dial)1-201-389-0920 (International Investors Dial)13751524 (Conference ID)Call meTM Feature: Click HereWebcast:C

    3/26/25 8:00:00 AM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $HUMA
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    Amendment: SEC Form SC 13D/A filed by Humacyte Inc.

    SC 13D/A - Humacyte, Inc. (0001818382) (Subject)

    11/20/24 7:10:08 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Amendment: SEC Form SC 13D/A filed by Humacyte Inc.

    SC 13D/A - Humacyte, Inc. (0001818382) (Subject)

    11/18/24 4:10:14 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Amendment: SEC Form SC 13D/A filed by Humacyte Inc.

    SC 13D/A - Humacyte, Inc. (0001818382) (Subject)

    9/3/24 4:11:41 PM ET
    $HUMA
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care