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    Amendment: SEC Form SCHEDULE 13D/A filed by Quantum-Si Incorporated

    9/11/25 5:04:02 PM ET
    $QSI
    Industrial Machinery/Components
    Industrials
    Get the next $QSI alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13D

    Under the Securities Exchange Act of 1934

    (Amendment No. 4)


    Quantum-Si Inc

    (Name of Issuer)


    Class A common stock, par value $0.0001 per share, Class B common stock, par value $0.0001 per share

    (Title of Class of Securities)


    74765K105

    (CUSIP Number)


    Jonathan M. Rothberg, Ph.D.
    c/o Quantum-Si Incorporated, 29 Business Park Drive
    Branford, CT, 06405
    (866) 688-7374

    (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)
    09/09/2025

    (Date of Event Which Requires Filing of This Statement)


    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. Checkbox not checked

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).






    SCHEDULE 13D

    CUSIP No.
    74765K105


    1 Name of reporting person

    ROTHBERG JONATHAN M
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    PF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    12,085,926.00
    8Shared Voting Power

    2,190,489.00
    9Sole Dispositive Power

    12,085,926.00
    10Shared Dispositive Power

    2,190,489.00
    11Aggregate amount beneficially owned by each reporting person

    14,276,415.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    7.8 %
    14Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:
    This Reporting Person's Table is for Class A common stock. Rows 7, 9 and 11 consists of (i) 2,568,443 shares of Class A common stock of Quantum-Si Incorporated (the ''Issuer'') held by Jonathan M. Rothberg, Ph.D., (ii) stock options to purchase 543,642 shares of Class A common stock of the Issuer which are exercisable within 60 days of September 9, 2025, held by Dr. Jonathan M. Rothberg and (iii) an aggregate of 8,973,841 shares of Class A common stock of the Issuer held by entities owned by trusts created for the benefit of Dr. Jonathan Rothberg's children, including shares of Class A common stock previously distributed from 2012 JMR Trust Common, LLC. Rows 8, 10 and 11 consists of (i) 1,917,067 shares of Class A common stock of the Issuer held by 23rd Century Capital LLC, and (ii) 273,422 shares of Class A common stock of the Issuer held by Dr. Jonathan Rothberg's spouse, Bonnie E. Gould Rothberg, M.D. Row 13 is calculated based on 182,557,698 shares of Class A common stock of the Issuer outstanding as of July 31, 2025.


    SCHEDULE 13D

    CUSIP No.
    74765K105


    1 Name of reporting person

    ROTHBERG JONATHAN M.
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    PF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    19,937,500.00
    8Shared Voting Power

    0.00
    9Sole Dispositive Power

    19,937,500.00
    10Shared Dispositive Power

    0.00
    11Aggregate amount beneficially owned by each reporting person

    19,937,500.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    100 %
    14Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:
    This Reporting Person's Table is for Class B common stock. Rows 7, 9 and 11 consists of (i) 17,943,750 shares of Class B common stock of the Issuer held by 4C Holdings I, LLC and (ii) 1,993,750 shares of Class B common stock of the Issuer held by 4C Holdings V, LLC. Row 13 is calculated based on 19,937,500 shares of Class B common stock of the Issuer outstanding as of July 31, 2025.


    SCHEDULE 13D

    CUSIP No.
    74765K105


    1 Name of reporting person

    23rd Century Capital LLC
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    PF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    8Shared Voting Power

    1,917,067.00
    9Sole Dispositive Power

    10Shared Dispositive Power

    1,917,067.00
    11Aggregate amount beneficially owned by each reporting person

    1,917,067.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    1.05 %
    14Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:
    This Reporting Person's table is for Class A common stock. Row 13 is calculated based on 182,557,698 shares of Class A common stock of the Issuer outstanding as of July 31, 2025.


    SCHEDULE 13D

    CUSIP No.
    74765K105


    1 Name of reporting person

    2012 JMR Trust Common, LLC
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    PF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    8Shared Voting Power

    9Sole Dispositive Power

    10Shared Dispositive Power

    11Aggregate amount beneficially owned by each reporting person

    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    0 %
    14Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:
    This Reporting Person's table is for Class A common stock. Row 13 is calculated based on 182,557,698 shares of Class A common stock of the Issuer outstanding as of July 31, 2025.


    SCHEDULE 13D

    CUSIP No.
    74765K105


    1 Name of reporting person

    4C Holdings I, LLC
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    PF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    8Shared Voting Power

    17,943,750.00
    9Sole Dispositive Power

    10Shared Dispositive Power

    17,943,750.00
    11Aggregate amount beneficially owned by each reporting person

    17,943,750.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    90 %
    14Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:
    This Reporting Person's table is for Class B common stock. Row 13 is calculated based on 19,937,500 shares of Class B common stock of the Issuer outstanding as of July 31, 2025.


    SCHEDULE 13D

    CUSIP No.
    74765K105


    1 Name of reporting person

    4C Holdings V, LLC
    2Check the appropriate box if a member of a Group (See Instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3SEC use only
    4 Source of funds (See Instructions)

    PF
    5 Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

    Checkbox not checked
    6Citizenship or place of organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    7Sole Voting Power

    8Shared Voting Power

    1,993,750.00
    9Sole Dispositive Power

    10Shared Dispositive Power

    1,993,750.00
    11Aggregate amount beneficially owned by each reporting person

    1,993,750.00
    12Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

    Checkbox not checked
    13Percent of class represented by amount in Row (11)

    10 %
    14Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:
    This Reporting Person's table is for Class B common stock. Row 13 is calculated based on 19,937,500 shares of Class B common stock of the Issuer outstanding as of July 31, 2025.


    SCHEDULE 13D

    Item 1.Security and Issuer
    (a)Title of Class of Securities:

    Class A common stock, par value $0.0001 per share, Class B common stock, par value $0.0001 per share
    (b)Name of Issuer:

    Quantum-Si Inc
    (c)Address of Issuer's Principal Executive Offices:

    29 BUSINESS PARK DRIVE, BRANFORD, CONNECTICUT , 06405.
    Item 1 Comment:
    Explanatory Note Amendment No. 4 to Schedule 13D ("Amendment No. 4") amends and supplements the Schedule 13D dated June 18, 2021, as amended by Amendment No. 1 filed on September 13, 2023, Amendment No. 2 filed on September 17, 2024 and Amendment No. 3 filed on December 31, 2024 (collectively, as amended, the "Schedule 13D") relating to the Class A common stock, par value $0.0001 per share ("Class A common stock"), and Class B common stock, par value $0.0001 per share, of Quantum-Si Incorporated, a Delaware corporation. Information reported in the Schedule 13D remains in effect except to the extent that it is amended, restated or superseded by information contained in this Amendment No. 4. Capitalized terms used but not defined herein have the meanings ascribed to them in the Schedule 13D.
    Item 4.Purpose of Transaction
     
    In connection with estate planning, entities owned by trusts created for the benefit of Dr. Jonathan Rothberg's children have entered into a trading plan pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended (the "Plan"), a copy of which is attached hereto as Exhibit 5. Pursuant to the Plan, sales of up to 8,973,841 shares of Class A common stock may be effected during the plan sales period beginning following the cooling-off period contained in Rule 10b5-1(c) on January 14, 2026 and ending on January 14, 2027 in accordance with the terms and conditions of the Plan. The sale of shares of Class A common stock under the Plan is subject to minimum price parameters included in the Plan, and there is no assurance that any shares of Class A common stock will be sold under the Plan.
    Item 7.Material to be Filed as Exhibits.
     
    Item 7 of the Schedule 13D is hereby amended by adding the following exhibit: 5. Rule 10b5-1 Trading Plan

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    ROTHBERG JONATHAN M
     
    Signature:/s/ Jonathan M. Rothberg
    Name/Title:Jonathan M. Rothberg, Ph.D.
    Date:09/11/2025
     
    ROTHBERG JONATHAN M.
     
    Signature:/s/ Jonathan M. Rothberg
    Name/Title:Jonathan M. Rothberg, Ph.D.
    Date:09/11/2025
     
    23rd Century Capital LLC
     
    Signature:/s/ Jonathan M. Rothberg
    Name/Title:Jonathan M. Rothberg, Ph.D., Member
    Date:09/11/2025
     
    2012 JMR Trust Common, LLC
     
    Signature:/s/ Jonathan M. Rothberg
    Name/Title:Jonathan M. Rothberg, Ph.D., Manager
    Date:09/11/2025
     
    4C Holdings I, LLC
     
    Signature:/s/ Jonathan M. Rothberg
    Name/Title:Jonathan M. Rothberg, Ph.D., Manager
    Date:09/11/2025
     
    4C Holdings V, LLC
     
    Signature:/s/ Jonathan M. Rothberg
    Name/Title:Jonathan M. Rothberg, Ph.D., Manager
    Date:09/11/2025
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