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    Amendment: SEC Form SCHEDULE 13G/A filed by Dyne Therapeutics Inc.

    11/13/25 4:23:17 PM ET
    $DYN
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $DYN alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13G


    UNDER THE SECURITIES EXCHANGE ACT OF 1934
    (Amendment No. 5)


    DYNE THERAPEUTICS, INC.

    (Name of Issuer)


    COMMON STOCK, $0.0001 PAR VALUE

    (Title of Class of Securities)


    26818M108

    (CUSIP Number)


    09/30/2025

    (Date of Event Which Requires Filing of this Statement)


    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
    Checkbox not checked   Rule 13d-1(b)
    Checkbox not checked   Rule 13d-1(c)
    Checkbox checked   Rule 13d-1(d)






    SCHEDULE 13G

    CUSIP No.
    26818M108


    1Names of Reporting Persons

    Atlas Venture Fund XI, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    5,697,508.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    5,697,508.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,697,508.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    4.0 %
    12Type of Reporting Person (See Instructions)

    PN


    SCHEDULE 13G

    CUSIP No.
    26818M108


    1Names of Reporting Persons

    Atlas Venture Associates XI, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    5,713,470.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    5,713,470.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,713,470.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    4.0 %
    12Type of Reporting Person (See Instructions)

    PN


    SCHEDULE 13G

    CUSIP No.
    26818M108


    1Names of Reporting Persons

    Atlas Venture Associates XI, LLC
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    5,713,470.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    5,713,470.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    5,713,470.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    4.0 %
    12Type of Reporting Person (See Instructions)

    OO


    SCHEDULE 13G

    CUSIP No.
    26818M108


    1Names of Reporting Persons

    Atlas Venture Opportunity Fund I, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    1,458,568.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    1,458,568.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,458,568.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.0 %
    12Type of Reporting Person (See Instructions)

    PN


    SCHEDULE 13G

    CUSIP No.
    26818M108


    1Names of Reporting Persons

    Atlas Venture Associates Opportunity I, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    1,458,568.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    1,458,568.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,458,568.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.0 %
    12Type of Reporting Person (See Instructions)

    PN


    SCHEDULE 13G

    CUSIP No.
    26818M108


    1Names of Reporting Persons

    Atlas Venture Associates Opportunity I, LLC
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    1,458,568.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    1,458,568.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,458,568.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.0 %
    12Type of Reporting Person (See Instructions)

    OO


    SCHEDULE 13G

    CUSIP No.
    26818M108


    1Names of Reporting Persons

    Atlas Venture Opportunity Fund II, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    1,958,427.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    1,958,427.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,958,427.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.4 %
    12Type of Reporting Person (See Instructions)

    PN


    SCHEDULE 13G

    CUSIP No.
    26818M108


    1Names of Reporting Persons

    Atlas Venture Associates Opportunity II, LP
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    1,958,427.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    1,958,427.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,958,427.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.4 %
    12Type of Reporting Person (See Instructions)

    PN


    SCHEDULE 13G

    CUSIP No.
    26818M108


    1Names of Reporting Persons

    Atlas Venture Associates Opportunity II, LLC
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    1,958,427.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    1,958,427.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,958,427.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    1.4 %
    12Type of Reporting Person (See Instructions)

    OO


    SCHEDULE 13G

    Item 1. 
    (a)Name of issuer:

    DYNE THERAPEUTICS, INC.
    (b)Address of issuer's principal executive offices:

    1560 TRAPELO ROAD, WALTHAM, MA, 02451.
    Item 2. 
    (a)Name of person filing:

    This Schedule 13G is filed by (i) Atlas Venture Fund XI, L.P., a Delaware limited partnership ("Atlas XI"), (ii) Atlas Venture Associates XI, L.P., a Delaware limited partnership ("AVA XI LP"), (iii) Atlas Venture Associates XI, LLC, a Delaware limited liability company ("AVA XI LLC" and together with Atlas XI and AVA XI LP, the "Fund XI Reporting Persons"), (iv) Atlas Venture Opportunity Fund I, L.P., a Delaware limited partnership ("AVO I"), (v) Atlas Venture Associates Opportunity I, L.P., a Delaware limited partnership ("AVAO LP"), (vi) Atlas Venture Associates Opportunity I, LLC, a Delaware limited liability company ("AVAO LLC" and together with AVO I and AVAO LP, the "Opportunity Fund Reporting Persons"), (vii) Atlas Venture Opportunity Fund II, L.P., a Delaware limited partnership ("AVO II"), (viii) Atlas Venture Associates Opportunity II, L.P., a Delaware limited partnership ("AVAO II LP") and (ix) Atlas Venture Associates Opportunity II, LLC, a Delaware limited liability company ("AVAO II LLC" and together with AVO II and AVAO II LP, the "Opportunity Fund II Reporting Persons" and together with the Fund XI Reporting Persons and Opportunity Fund Reporting Persons, the "Reporting Persons").
    (b)Address or principal business office or, if none, residence:

    300 Technology Square, 8th Floor Cambridge, Massachusetts 02139
    (c)Citizenship:

    Each of Atlas XI, AVA XI LP, AVO I, AVAO LP, AVO II and AVAO II LP is a Delaware limited partnership. Each of AVA XI LLC, AVAO LLC and AVAO II LLC is a Delaware limited liability company.
    (d)Title of class of securities:

    COMMON STOCK, $0.0001 PAR VALUE
    (e)CUSIP No.:

    26818M108
    Item 3.If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
    (a)Checkbox not checked   Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)Checkbox not checked   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)Checkbox not checked   Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)Checkbox not checked   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)Checkbox not checked   An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
    (f)Checkbox not checked   An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
    (g)Checkbox not checked   A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
    (h)Checkbox not checked   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)Checkbox not checked   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j)Checkbox not checked   A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
           please specify the type of institution:
    (k)Checkbox not checked   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
     
    Item 4.Ownership
    (a)Amount beneficially owned:

    Atlas XI is the record owner of 5,697,508 shares of Common Stock. AVA XI LP is the general partner of Atlas XI and AVA XI LLC is the general partner of AVA XI LP. Each of Atlas XI, AVA XI LP and AVA XI LLC has shared voting and dispositive power over the shares held by Atlas XI. As such, each of Atlas XI, AVA XI LP and AVA XI LLC may be deemed to beneficially own the shares held by Atlas XI. AVA XI LP is the record owner of 15,962 shares of Common Stock. AVA XI LLC is the general partner of AVA XI LP. Each of AVA XI LP and AVA XI LLC has shared voting and dispositive power over the shares held by AVA XI LP. As such, each of AVA XI LP and AVA XI LLC may be deemed to beneficially own the shares held by AVA XI LP. AVO I is the record owner of 1,458,568 shares of Common Stock. AVAO LP is the general partner of AVO I and AVAO LLC is the general partner of AVAO LP. Each of AVO I, AVAO LP and AVAO LLC has shared voting and dispositive power over the shares held by AVO I. As such, each of AVO I, AVAO LP and AVAO LLC may be deemed to beneficially own the shares held by AVO I. AVO II is the record owner of 1,958,427 shares of Common Stock. AVAO II LP is the general partner of AVO II and AVAO II LLC is the general partner of AVAO II LP. Each of AVO II, AVAO II LP and AVAO II LLC has shared voting and dispositive power over the shares held by AVO II. As such, each of AVO II, AVAO II LP and AVAO II LLC may be deemed to beneficially own the shares held by AVO II.
    (b)Percent of class:

    Each of the Fund XI Reporting Persons may be deemed to beneficially own 4.0% of the Issuer's outstanding Common Stock. Each of the Opportunity Fund Reporting Persons may be deemed to beneficially own 1.0% of the Issuer's outstanding Common Stock. Each of the Opportunity Fund II Reporting Persons may be deemed to beneficially own 1.4%, of the Issuer's outstanding Common Stock. These percentages are calculated based upon 142,824,687 outstanding shares of Common Stock of the Issuer as of October 31, 2025, as reported in the Issuer's Form 10-Q, filed with the Securities and Exchange Commission on November 5, 2025. Collectively, the Reporting Persons beneficially own an aggregate of 9,130,465 shares of Common Stock, which represents 6.4% of the Issuer's outstanding Common Stock. The Fund XI Reporting Persons, Opportunity Fund Reporting Persons and Opportunity Fund II Reporting Persons are under common control and as a result, the Reporting Persons may be deemed to be members of a group. However, the Reporting Persons disclaim such group membership, and this Schedule 13G shall not be deemed an admission that the Reporting Persons are members of a group for purposes of Section 13 or for any other purposes.
    (c)Number of shares as to which the person has:
     (i) Sole power to vote or to direct the vote:

    None of the Reporting Persons have the sole power to direct the vote of the Common Stock.

     (ii) Shared power to vote or to direct the vote:

    Atlas XI shares power to vote or direct the vote of 5,697,508 shares of Common Stock. Each of AVA XI LP and AVA XI LLC shares power to vote or direct the vote of 5,713,470 shares of Common Stock. Each Opportunity Fund Reporting Person shares power to vote or direct the vote of 1,458,568 shares of Common Stock. Each Opportunity Fund II Reporting Person shares power to vote or direct the vote of 1,958,427 shares of Common Stock.

     (iii) Sole power to dispose or to direct the disposition of:

    None of the Reporting Persons have the sole power to dispose or to direct the disposition of the Common Stock.

     (iv) Shared power to dispose or to direct the disposition of:

    Atlas XI shares power to dispose or to direct the disposition of 5,697,508 shares of Common Stock. Each of AVA XI LP and AVA XI LLC shares power to dispose or to direct the disposition of 5,713,470 shares of Common Stock. Each Opportunity Fund Reporting Person shares power to dispose or to direct the disposition of 1,458,568 shares of Common Stock. Each Opportunity Fund II Reporting Person shares power to vote or direct the vote of 1,958,427 shares of Common Stock.

    Item 5.Ownership of 5 Percent or Less of a Class.
     
    Item 6.Ownership of more than 5 Percent on Behalf of Another Person.
     
    Not Applicable
    Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
     
    Not Applicable
    Item 8.Identification and Classification of Members of the Group.
     
    Not Applicable
    Item 9.Notice of Dissolution of Group.
     
    Not Applicable

    Item 10.Certifications:
     
    Not Applicable

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Atlas Venture Fund XI, L.P.
     
    Signature:/s/ Ommer Chohan
    Name/Title:By: Atlas Venture Associates XI, L.P., its general partner, By: Atlas Venture Associates XI, LLC, its general partner, By: Ommer Chohan, its CFO
    Date:11/13/2025
     
    Atlas Venture Associates XI, L.P.
     
    Signature:/s/ Ommer Chohan
    Name/Title:By: Atlas Venture Associates XI, LLC, its general partner, By: Ommer Chohan, its CFO
    Date:11/13/2025
     
    Atlas Venture Associates XI, LLC
     
    Signature:/s/ Ommer Chohan
    Name/Title:Ommer Chohan, its CFO
    Date:11/13/2025
     
    Atlas Venture Opportunity Fund I, L.P.
     
    Signature:/s/ Ommer Chohan
    Name/Title:By: Atlas Venture Associates Opportunity I L.P., its GP, By: Atlas Venture Associates Opportunity I LLC, its GP, By: Ommer Chohan, its CFO
    Date:11/13/2025
     
    Atlas Venture Associates Opportunity I, L.P.
     
    Signature:/s/ Ommer Chohan
    Name/Title:By: Atlas Venture Associates Opportunity I LLC, its GP, By: Ommer Chohan, its CFO
    Date:11/13/2025
     
    Atlas Venture Associates Opportunity I, LLC
     
    Signature:/s/ Ommer Chohan
    Name/Title:Ommer Chohan, its CFO
    Date:11/13/2025
     
    Atlas Venture Opportunity Fund II, L.P.
     
    Signature:/s/ Ommer Chohan
    Name/Title:By: Atlas Venture Associates Opportunity II L.P., its GP, By: Atlas Venture Associates Opportunity II LLC, its GP, By: Ommer Chohan, its CFO
    Date:11/13/2025
     
    Atlas Venture Associates Opportunity II, LP
     
    Signature:/s/ Ommer Chohan
    Name/Title:By: Atlas Venture Associates Opportunity II LLC, its GP, By: Ommer Chohan, its CFO
    Date:11/13/2025
     
    Atlas Venture Associates Opportunity II, LLC
     
    Signature:/s/ Ommer Chohan
    Name/Title:Ommer Chohan, its CFO
    Date:11/13/2025
    Exhibit Information

    JOINT FILING AGREEMENT

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    CEO & President Cox John bought $1,057,216 worth of shares (32,000 units at $33.04) (SEC Form 4)

    4 - Dyne Therapeutics, Inc. (0001818794) (Issuer)

    9/4/24 5:42:18 PM ET
    $DYN
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    Kersten Dirk bought $29,999,988 worth of shares (1,714,285 units at $17.50) (SEC Form 4)

    4 - Dyne Therapeutics, Inc. (0001818794) (Issuer)

    1/11/24 4:31:55 PM ET
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    Dyne Therapeutics Appoints Brian Posner to its Board of Directors

    WALTHAM, Mass., Oct. 02, 2025 (GLOBE NEWSWIRE) -- Dyne Therapeutics, Inc. (NASDAQ:DYN), a clinical-stage company focused on delivering functional improvement for people living with genetically driven neuromuscular diseases, today announced the appointment of Brian Posner to its Board of Directors. Mr. Posner brings 35 years of executive, investment and board leadership expertise to the company. "Brian is joining our Board during a pivotal phase, as we transition to becoming a fully integrated biotechnology company poised to commercialize our first potential product in 2027," said Jason Rhodes, chairman of Dyne's Board of Directors and partner at Atlas Venture. "With a perspective shaped b

    10/2/25 4:05:00 PM ET
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    Satellos Appoints Dr. Wildon Farwell as Chief Medical Officer

    Brings a successful track record in clinical development and regulatory approval of innovative neuromuscular therapies Satellos Bioscience Inc. (TSX:MSCL, OTCQB:MSCLF) ("Satellos" or the "Company"), a biotech company developing new small molecule therapeutic approaches to improve the treatment of muscle diseases, today announced the appointment of Wildon Farwell, M.D., MPH, as chief medical officer ("CMO"). Dr. Farwell joins Satellos from Dyne Therapeutics (NASDAQ:DYN), where he most recently served as CMO and medical advisor. "We are thrilled to welcome Dr. Farwell as our CMO," said Frank Gleeson, Satellos co-founder and CEO. "He brings deep expertise in global clinical development — p

    7/16/25 7:00:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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    Dyne Therapeutics Announces CEO Transition

    - John Cox, Industry Leader with Global Experience in Rare Disease Commercialization, Joins Dyne as President and CEO - WALTHAM, Mass., March 25, 2024 (GLOBE NEWSWIRE) -- Dyne Therapeutics, Inc. (NASDAQ:DYN), a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases, today announced the appointment of John Cox as president, chief executive officer (CEO) and a member of the Board of Directors, effective immediately. He succeeds Joshua Brumm, who has chosen to step down from these roles to pursue a career in healthcare investing. Mr. Brumm will serve as an advisor to Dyne to help ensure a seamles

    3/25/24 7:30:00 AM ET
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    $DYN
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    Amendment: SEC Form SC 13G/A filed by Dyne Therapeutics Inc.

    SC 13G/A - Dyne Therapeutics, Inc. (0001818794) (Subject)

    11/14/24 5:46:12 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    Amendment: SEC Form SC 13G/A filed by Dyne Therapeutics Inc.

    SC 13G/A - Dyne Therapeutics, Inc. (0001818794) (Subject)

    11/14/24 4:32:40 PM ET
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    Biotechnology: Pharmaceutical Preparations
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    Amendment: SEC Form SC 13G/A filed by Dyne Therapeutics Inc.

    SC 13G/A - Dyne Therapeutics, Inc. (0001818794) (Subject)

    11/14/24 4:23:11 PM ET
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    Dyne Therapeutics Announces Positive Topline Results from Phase 1/2 DELIVER Trial of Z-Rostudirsen in Duchenne Muscular Dystrophy (DMD)

    - Registrational Expansion Cohort (REC) met primary endpoint, demonstrating statistically significant increase in dystrophin to 5.46% at 6 months (muscle content-adjusted; p<0.0001), replicating the same 7-fold change from baseline previously observed at the registrational dose - - Functional improvement was observed across multiple clinical endpoints at 6 months in REC; lung function was preserved at 6 months - - New positive long-term results from DELIVER trial showed sustained functional improvement across all assessed endpoints through 24 months - - Continued favorable safety and tolerability profile - - Submission for U.S. Accelerated Approval on track for Q2 2026 - - Investor even

    12/8/25 6:30:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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    Dyne Therapeutics to Host Investor Conference Call and Webcast to Review Topline Results from Registrational Expansion Cohort (REC) of DELIVER Clinical Trial of Z-Rostudirsen (DYNE-251) in Duchenne Muscular Dystrophy; Tomorrow, December 8 at 8:00 a.m. ET

    WALTHAM, Mass., Dec. 07, 2025 (GLOBE NEWSWIRE) -- Dyne Therapeutics, Inc. (NASDAQ:DYN), a clinical-stage company focused on delivering functional improvement for people living with genetically driven neuromuscular diseases, today announced that it plans to announce topline clinical results from the Registrational Expansion Cohort (REC) of the Phase 1/2 DELIVER trial of zeleciment rostudirsen (z-rostudirsen, also known as DYNE-251) on December 8, 2025, and to host a webcast at 8:00 a.m. ET. The company intends to issue a press release prior to the start of the event. Investor Conference Call and WebcastThe webcast will be available on the Events & Presentations page of the Investors & Medi

    12/7/25 11:00:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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    Dyne Therapeutics Announces FDA Breakthrough Therapy Designation for DYNE-101 and Updated Plan for Accelerated Approval in DM1 Following Type C Meeting

    - Based on Type C meeting and new data, Dyne submitted revised ACHIEVE trial protocol to FDA elevating vHOT to primary endpoint for U.S. Accelerated Approval - - New positive clinical data from Phase 1/2 ACHIEVE trial support vHOT as early indicator of clinical benefit with DYNE-101 in DM1 - - Ongoing Registrational Expansion Cohort in ACHIEVE trial to enroll 60 participants and include sites in U.S. - - Company to host an investor and analyst conference call today, June 17, at 8:00 a.m. ET - WALTHAM, Mass., June 17, 2025 (GLOBE NEWSWIRE) -- Dyne Therapeutics, Inc. (NASDAQ:DYN), a clinical-stage company focused on delivering functional improvement for people living with genetically

    6/17/25 7:00:00 AM ET
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    Biotechnology: Pharmaceutical Preparations
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