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    Amendment: SEC Form SCHEDULE 13G/A filed by Indivior PLC

    11/13/25 4:27:43 PM ET
    $INDV
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $INDV alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13G


    UNDER THE SECURITIES EXCHANGE ACT OF 1934
    (Amendment No. 3)


    Indivior PLC

    (Name of Issuer)


    Ordinary Shares, $0.50 nominal value per share

    (Title of Class of Securities)


    G4766E116

    (CUSIP Number)


    11/10/2025

    (Date of Event Which Requires Filing of this Statement)


    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
    Checkbox not checked   Rule 13d-1(b)
    Checkbox checked   Rule 13d-1(c)
    Checkbox not checked   Rule 13d-1(d)






    SCHEDULE 13G

    CUSIP No.
    G4766E116


    1Names of Reporting Persons

    Deerfield Mgmt, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    4,614,498.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    4,614,498.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    4,614,498.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    3.70 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  Comment for Type of Reporting Person: Notes to Rows 6, 8 and 9: Comprised of 4,614,498 Ordinary Shares held by Deerfield Partners, L.P., of which Deerfield Mgmt, L.P. is the general partner. See Item 4 for information as to the Reporting Person's beneficial ownership as of September 30, 2025.


    SCHEDULE 13G

    CUSIP No.
    G4766E116


    1Names of Reporting Persons

    Deerfield Management Company, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    4,614,498.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    4,614,498.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    4,614,498.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    3.70 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  Comment for Type of Reporting Person: Notes to Rows 6, 8 and 9: Comprised of 4,614,498 Ordinary Shares held by Deerfield Partners, L.P., of which Deerfield Management Company, L.P. is the investment advisor. See Item 4 for information as to the Reporting Person's beneficial ownership as of September 30, 2025.


    SCHEDULE 13G

    CUSIP No.
    G4766E116


    1Names of Reporting Persons

    Deerfield Partners, L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    4,614,498.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    4,614,498.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    4,614,498.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    3.70 %
    12Type of Reporting Person (See Instructions)

    PN

    Comment for Type of Reporting Person:  Comment for Type of Reporting Person: Notes to Rows 6, 8 and 9: See Item 4 for information as to the Reporting Person's beneficial ownership as of September 30, 2025.


    SCHEDULE 13G

    CUSIP No.
    G4766E116


    1Names of Reporting Persons

    James E. Flynn
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    4,614,498.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    4,614,498.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    4,614,498.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    3.70 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  Comment for Type of Reporting Person: Notes to Rows 6, 8 and 9: Comprised of 4,614,498 shares of common stock held by Deerfield Partners, L.P. See Item 4 for information as to the Reporting Person's beneficial ownership as of September 30, 2025.


    SCHEDULE 13G

    Item 1. 
    (a)Name of issuer:

    Indivior PLC
    (b)Address of issuer's principal executive offices:

    10710 Midlothian Turnpike, Suite 125, North Chesterfield, Virginia 23235
    Item 2. 
    (a)Name of person filing:

    James E. Flynn, Deerfield Mgmt, L.P., Deerfield Management Company, L.P. and Deerfield Partners, L.P.
    (b)Address or principal business office or, if none, residence:

    James E. Flynn, Deerfield Mgmt, L.P., Deerfield Management Company, L.P. and Deerfield Partners, L.P., 345 Park Avenue South, 12th Floor, New York, NY 10010
    (c)Citizenship:

    Deerfield Mgmt, L.P., Deerfield Management Company, L.P. and Deerfield Partners, L.P. - Delaware limited partnerships; James E. Flynn - United States citizen
    (d)Title of class of securities:

    Ordinary Shares, $0.50 nominal value per share
    (e)CUSIP No.:

    G4766E116
    Item 3.If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
    (a)Checkbox not checked   Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)Checkbox not checked   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)Checkbox not checked   Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)Checkbox not checked   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)Checkbox not checked   An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
    (f)Checkbox not checked   An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
    (g)Checkbox not checked   A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
    (h)Checkbox not checked   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)Checkbox not checked   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j)Checkbox not checked   A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
           please specify the type of institution:
    (k)Checkbox not checked   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
     
    Item 4.Ownership
    (a)Amount beneficially owned:

    Deerfield Mgmt, L.P. - 4,614,498 shares Deerfield Management Company, L.P. - 4,614,498 shares Deerfield Partners, L.P. - 4,614,498 shares James E. Flynn - 4,614,498 shares Explanatory Note: As of September 30, 2025, the Reporting Persons beneficially owned 6,986,811 of the issuer's Ordinary Shares, which represented 5.6% of the outstanding Ordinary Shares. As of November 10, 2025 (prior to reporting the Reporting Persons' beneficial ownership as of September 30, 2025), the Reporting Persons ceased to beneficially own more than 5% of the outstanding Ordinary Shares. Accordingly, this Amendment No. 3 includes information as to the Reporting Persons' beneficial ownership as of September 30, 2025 and as of the date this Amendment No. 3 is being filed.
    (b)Percent of class:

    Deerfield Mgmt, L.P. - 3.70% Deerfield Management Company, L.P. - 3.70% Deerfield Partners, L.P. - 3.70% James E. Flynn - 3.70%
    (c)Number of shares as to which the person has:
     (i) Sole power to vote or to direct the vote:

    All Reporting Persons - 0

     (ii) Shared power to vote or to direct the vote:

    Deerfield Mgmt, L.P. - 4,614,498 Deerfield Management Company, L.P. - 4,614,498 Deerfield Partners, L.P. - 4,614,498 James E. Flynn - 4,614,498

     (iii) Sole power to dispose or to direct the disposition of:

    All Reporting Persons - 0

     (iv) Shared power to dispose or to direct the disposition of:

    Deerfield Mgmt, L.P. - 4,614,498 Deerfield Management Company, L.P. - 4,614,498 Deerfield Partners, L.P. - 4,614,498 James E. Flynn - 4,614,498

    Item 5.Ownership of 5 Percent or Less of a Class.
     
    Item 6.Ownership of more than 5 Percent on Behalf of Another Person.
     
    Not Applicable
    Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
     
    Not Applicable
    Item 8.Identification and Classification of Members of the Group.
     
    If a group has filed this schedule pursuant to §240.13d-1(b)(1)(ii)(J), so indicate under Item 3(j) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to §240.13d-1(c) or §240.13d-1(d), attach an exhibit stating the identity of each member of the group.


    See Exhibit B
    Item 9.Notice of Dissolution of Group.
     
    Not Applicable

    Item 10.Certifications:
     
    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Deerfield Mgmt, L.P.
     
    Signature:/s/ Jonathan Isler
    Name/Title:Jonathan Isler, Attorney-In-Fact
    Date:11/13/2025
     
    Deerfield Management Company, L.P.
     
    Signature:/s/ Jonathan Isler
    Name/Title:Jonathan Isler, Attorney-In-Fact
    Date:11/13/2025
     
    Deerfield Partners, L.P.
     
    Signature:/s/ Jonathan Isler
    Name/Title:Jonathan Isler, Attorney-In-Fact
    Date:11/13/2025
     
    James E. Flynn
     
    Signature:/s/ Jonathan Isler
    Name/Title:Jonathan Isler, Attorney-In-Fact
    Date:11/13/2025
    Exhibit Information

    Exhibit A. Joint Filing Agreement. Exhibit B. Item 8 Statement. Exhibit C. Power of Attorney (1). (1) Power of Attorney previously filed as Exhibit 24 to a Form 3 with regard to BiomX Inc. filed with the Securities and Exchange Commission on March 19, 2024 by Deerfield Private Design Fund V, L.P., Deerfield Healthcare Innovations Fund II, L.P., Deerfield Mgmt V, L.P., Deerfield Mgmt HIF II, L.P., Deerfield Management Company, L.P. and James E. Flynn.

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