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    Amendment: SEC Form SCHEDULE 13G/A filed by Mirum Pharmaceuticals Inc.

    2/14/25 12:01:31 PM ET
    $MIRM
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $MIRM alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13G


    UNDER THE SECURITIES EXCHANGE ACT OF 1934
    (Amendment No. 2)


    Inozyme Pharma, Inc.

    (Name of Issuer)


    Common Stock, par value $0.0001 per share

    (Title of Class of Securities)


    45790W108

    (CUSIP Number)


    12/31/2024

    (Date of Event Which Requires Filing of this Statement)


    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
    Checkbox checked   Rule 13d-1(b)
    Checkbox not checked   Rule 13d-1(c)
    Checkbox not checked   Rule 13d-1(d)






    SCHEDULE 13G

    CUSIP No.
    45790W108


    1Names of Reporting Persons

    Eventide Asset Management, LLC
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    2,220,000.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    2,220,000.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    2,220,000.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    3.46 %
    12Type of Reporting Person (See Instructions)

    IA


    SCHEDULE 13G

    CUSIP No.
    45790W108


    1Names of Reporting Persons

    Finny Kuruvilla, M.D., Ph. D.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    2,220,000.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    2,220,000.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    2,220,000.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    3.46 %
    12Type of Reporting Person (See Instructions)

    HC, IN


    SCHEDULE 13G

    CUSIP No.
    45790W108


    1Names of Reporting Persons

    Robin C. John
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED STATES
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    2,220,000.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    2,220,000.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    2,220,000.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    3.46 %
    12Type of Reporting Person (See Instructions)

    HC, IN


    SCHEDULE 13G

    Item 1. 
    (a)Name of issuer:

    Inozyme Pharma, Inc.
    (b)Address of issuer's principal executive offices:

    321 Summer Street, Suite 400, Boston, Massachusetts 02210
    Item 2. 
    (a)Name of person filing:

    Eventide Asset Management, LLC Finny Kuruvilla, M.D., Ph.D. Robin C. John
    (b)Address or principal business office or, if none, residence:

    Eventide, Kuruvilla and John: One International Place, Suite 4210 Boston, Massachusetts 02110
    (c)Citizenship:

    Eventide: Delaware Kuruvilla: United States John: United States
    (d)Title of class of securities:

    Common Stock, par value $0.0001 per share
    (e)CUSIP No.:

    45790W108
    Item 3.If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
    (a)Checkbox not checked   Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)Checkbox not checked   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)Checkbox not checked   Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)Checkbox not checked   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)Checkbox checked   An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
    (f)Checkbox not checked   An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
    (g)Checkbox checked   A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
    (h)Checkbox not checked   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)Checkbox not checked   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j)Checkbox not checked   A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
           please specify the type of institution:
    (k)Checkbox not checked   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
     
    Item 4.Ownership
    (a)Amount beneficially owned:

    Eventide: 2,220,000 Kuruvilla: 2,220,000 John: 2,220,000
    (b)Percent of class:

    Eventide: 3.46% Kuruvilla: 3.46% John: 3.46%
    (c)Number of shares as to which the person has:
     (i) Sole power to vote or to direct the vote:

    Eventide: 2,220,000 Kuruvilla: 0 John: 0

     (ii) Shared power to vote or to direct the vote:

    Eventide: 0 Kuruvilla: 2,220,000 John: 2,220,000

     (iii) Sole power to dispose or to direct the disposition of:

    Eventide: 2,220,000 Kuruvilla: 0 John: 0

     (iv) Shared power to dispose or to direct the disposition of:

    Eventide: 0 Kuruvilla: 2,220,000 John: 2,220,000

    Item 5.Ownership of 5 Percent or Less of a Class.
     
    Checkbox checked    Ownership of 5 percent or less of a class
    Item 6.Ownership of more than 5 Percent on Behalf of Another Person.
     
    Not Applicable
    Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
     
    Not Applicable
    Item 8.Identification and Classification of Members of the Group.
     
    Not Applicable
    Item 9.Notice of Dissolution of Group.
     
    Not Applicable

    Item 10.Certifications:
     
    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. In accordance with Rule 13d-4 of the Securities Exchange Act of 1934, each of the persons filing this statement expressly disclaim the beneficial ownership of the securities covered by this statement and the filing of this report shall not be construed as an admission by such persons that they are the beneficial owners of such securities.

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Eventide Asset Management, LLC
     
    Signature:/s/ Peter J. Luiso
    Name/Title:Peter J. Luiso, General Counsel
    Date:02/10/2025
     
    Finny Kuruvilla, M.D., Ph. D.
     
    Signature:/s/ Finny Kuruvilla, M.D., Ph. D.
    Name/Title:Finny Kuruvilla, M.D., Ph. D.
    Date:02/10/2025
     
    Robin C. John
     
    Signature:/s/ Robin C. John
    Name/Title:Robin C. John
    Date:02/10/2025
    Exhibit Information

    EX 1

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