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    Amendment: SEC Form SCHEDULE 13G/A filed by Quince Therapeutics Inc.

    4/30/25 4:06:36 PM ET
    $QNCX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $QNCX alert in real time by email



    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13G


    UNDER THE SECURITIES EXCHANGE ACT OF 1934
    (Amendment No. 1)


    Quince Therapeutics, Inc.

    (Name of Issuer)


    Common Stock, par value $0.001 per share

    (Title of Class of Securities)


    22053A107

    (CUSIP Number)


    03/31/2025

    (Date of Event Which Requires Filing of this Statement)


    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
    Checkbox checked   Rule 13d-1(b)
    Checkbox not checked   Rule 13d-1(c)
    Checkbox not checked   Rule 13d-1(d)






    SCHEDULE 13G

    CUSIP No.
    22053A107


    1Names of Reporting Persons

    Sofinnova Capital VIII
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    FRANCE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    1,197,711.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    1,197,711.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,197,711.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    2.7 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  Note to Items 5 and 6: Sofinnova Partners SAS, a French corporation ("SP SAS"), the management company of Sofinnova Capital VIII ("SC VIII"), may be deemed to have sole voting power, and Antoine Papiernik ("Papiernik"), Henrijette Richter ("Richter"), Maina Bhaman ("Bhaman"), Graziano Seghezzi ("Seghezzi"), Anta Gkelou ("Gkelou"), and Karl Naegler ("Naegler") the members of the investment committee of SC VIII, may be deemed to have shared power to vote these shares. Note to Items 7 and 8: SP SAS, the management company of SC VIII, may be deemed to have sole voting power, and Papiernik, Richter, Bhaman, Seghezzi, Gkelou, and Naegler, the members of the investment committee of SC VIII, may be deemed to have shared power to vote these shares.


    SCHEDULE 13G

    CUSIP No.
    22053A107


    1Names of Reporting Persons

    Sofinnova Partners SAS, a French Corporation
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    FRANCE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    1,197,711.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    1,197,711.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,197,711.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    2.7 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  Note to Items 5 and 6: SP SAS, the management company of SC VIII, may be deemed to have sole voting power, and Papiernik, Richter, Bhaman, Seghezzi, Gkelou and Naegler, the members of the investment committee of SC VIII, may be deemed to have shared power to vote these shares. Note to Items 7 and 8: SP SAS, the management company of SC VIII, may be deemed to have sole power to dispose of these shares, and Papiernik, Richter, Bhaman, Seghezzi, Gkelou and Naegler, the members of the investment committee of SC VIII, may be deemed to have shared power to dispose of these shares.


    SCHEDULE 13G

    CUSIP No.
    22053A107


    1Names of Reporting Persons

    Antoine Papiernik
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    FRANCE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    1,197,711.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    1,197,711.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,197,711.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    2.7 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  Note to Items 5 and 6: SP SAS, the management company of SC VIII, may be deemed to have sole voting power, and Papiernik, a member of the investment committee of SC VIII, may be deemed to have shared power to vote these shares. Note to Items 7 and 8: SP SAS, the management company of SC VIII, may be deemed to have sole power to dispose of these shares, and Papiernik, a member of the investment committee of SC VIII, may be deemed to have shared power to dispose of these shares.


    SCHEDULE 13G

    CUSIP No.
    22053A107


    1Names of Reporting Persons

    Henrijette Richter
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DENMARK
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    1,197,711.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    1,197,711.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,197,711.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    2.7 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  Note to Items 5 and 6: SP SAS, the management company of SC VIII, may be deemed to have sole voting power, and Richter, a member of the investment committee of SC VIII, may be deemed to have shared power to vote these shares. Note to Items 7 and 8: SP SAS, the management company of SC VIII, may be deemed to have sole power to dispose of these shares, and Richter, a member of the investment committee of SC VIII, may be deemed to have shared power to dispose of these shares.


    SCHEDULE 13G

    CUSIP No.
    22053A107


    1Names of Reporting Persons

    Maina Bhaman
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    UNITED KINGDOM
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    1,197,711.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    1,197,711.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,197,711.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    2.7 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  Note to Items 5 and 6: SP SAS, the management company of SC VIII, may be deemed to have sole voting power, and Bhaman, a member of the investment committee of SC VIII, may be deemed to have shared power to vote these shares. Note to Items 7 and 8: SP SAS, the management company of SC VIII, may be deemed to have sole power to dispose of these shares, and Bhaman, a member of the investment committee of SC VIII, may be deemed to have shared power to dispose of these shares.


    SCHEDULE 13G

    CUSIP No.
    22053A107


    1Names of Reporting Persons

    Graziano Seghezzi
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    FRANCE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    1,197,711.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    1,197,711.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,197,711.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    2.7 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  Note to Items 5 and 6: SP SAS, the management company of SC VIII, may be deemed to have sole voting power, and Seghezzi, a member of the investment committee of SC VIII, may be deemed to have shared power to vote these shares. Note to Items 7 and 8: SP SAS, the management company of SC VIII, may be deemed to have sole power to dispose of these shares, and Seghezzi, a member of the investment committee of SC VIII, may be deemed to have shared power to dispose of these shares.


    SCHEDULE 13G

    CUSIP No.
    22053A107


    1Names of Reporting Persons

    Anta Gkelou
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    GREECE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    1,197,711.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    1,197,711.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,197,711.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    2.7 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  Note to Items 5 and 6: SP SAS, the management company of SC VIII, may be deemed to have sole voting power, and Gkelou, a member of the investment committee of SC VIII, may be deemed to have shared power to vote these shares. Note to Items 7 and 8: SP SAS, the management company of SC VIII, may be deemed to have sole power to dispose of these shares, and Gkelou, a member of the investment committee of SC VIII, may be deemed to have shared power to dispose of these shares.


    SCHEDULE 13G

    CUSIP No.
    22053A107


    1Names of Reporting Persons

    Karl Naegler
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    GERMANY
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    1,197,711.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    1,197,711.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    1,197,711.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    2.7 %
    12Type of Reporting Person (See Instructions)

    IN

    Comment for Type of Reporting Person:  Note to Items 5 and 6: SP SAS, the management company of SC VIII, may be deemed to have sole voting power, and Naegler, a member of the investment committee of SC VIII, may be deemed to have shared power to vote these shares. Note to Items 7 and 8: SP SAS, the management company of SC VIII, may be deemed to have sole power to dispose of these shares, and Naegler, a member of the investment committee of SC VIII, may be deemed to have shared power to dispose of these shares.


    SCHEDULE 13G

    Item 1. 
    (a)Name of issuer:

    Quince Therapeutics, Inc.
    (b)Address of issuer's principal executive offices:

    611 Gateway Blvd., Suite 273, South San Francisco, Ca 94080
    Item 2. 
    (a)Name of person filing:

    The persons and entities filing this Schedule 13G/A are Sofinnova Capital VIII ("SC VIII"), Sofinnova Partners SAS ("SP SAS"), Antoine Papiernik ("Papiernik"), Henrijette Richter ("Richter"), Maina Bhaman ("Bhaman"), Graziano Seghezzi ("Seghezzi"), Anta Gkelou ("Gkleou"), and Karl Naegler ("Naegler"), the members of the investment committee of SC VIII (together with SC VIII and SP SAS, the "Filing Persons"). SP SAS is the management company of SC VIII.
    (b)Address or principal business office or, if none, residence:

    The address of the principal place of business for each of the Filing Persons is Sofinnova Partners SAS, 7-11 boulevard Hausmann 75009 Paris, France.
    (c)Citizenship:

    SC VIII is a French Partnership. SP SAS is a French Corporation. Papiernik is a French citizen. Richter is a Danish citizen. Bhaman is a British citizen. Seghezzi is a French citizen. Gkelou is a Greek citizen. Naegler is a German citizen.
    (d)Title of class of securities:

    Common Stock, par value $0.001 per share
    (e)CUSIP No.:

    22053A107
    Item 3.If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
    (a)Checkbox not checked   Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)Checkbox not checked   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)Checkbox not checked   Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)Checkbox not checked   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)Checkbox not checked   An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
    (f)Checkbox not checked   An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
    (g)Checkbox not checked   A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
    (h)Checkbox not checked   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)Checkbox not checked   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j)Checkbox checked   A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
           please specify the type of institution:
    (k)Checkbox not checked   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
     
    Investment Adviser
    Item 4.Ownership
    (a)Amount beneficially owned:

    See Row 9 of the cover page for each of the Filing Persons. The filing of this Schedule 13G/A shall not be construed as an admission by Papiernik, Richter, Bhaman, Seghezzi, Gkelou, and Naegler that such person is, for the purposes of Section 13(d) of the Securities Exchange Act of 1934, the beneficial owner of any securities covered by this Statement.
    (b)Percent of class:

    See Row 11 of the cover page for each of the Filing Persons. Ownership is stated as of March 31, 2025 and the ownership percentages are based on 44,001,643 shares outstanding as of March 13, 2025, as disclosed by Quince Therapeutics, Inc. in its Annual Report on Form 10-K filed with the SEC on March 24, 2025.
    (c)Number of shares as to which the person has:
     (i) Sole power to vote or to direct the vote:

    See Row 5 of the cover page for each of the Filing Persons.

     (ii) Shared power to vote or to direct the vote:

    See Row 6 of the cover page for each of the Filing Persons.

     (iii) Sole power to dispose or to direct the disposition of:

    See Row 7 of the cover page for each of the Filing Persons.

     (iv) Shared power to dispose or to direct the disposition of:

    See Row 8 of the cover page for each of the Filing Persons.

    Item 5.Ownership of 5 Percent or Less of a Class.
     
    Checkbox checked    Ownership of 5 percent or less of a class
    Item 6.Ownership of more than 5 Percent on Behalf of Another Person.
     
    Not Applicable
    Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
     
    Not Applicable
    Item 8.Identification and Classification of Members of the Group.
     
    Not Applicable
    Item 9.Notice of Dissolution of Group.
     
    Not Applicable

    Item 10.Certifications:
     
    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. By signing below I certify that, to the best of my knowledge and belief, the foreign regulatory scheme applicable to Investment Advisers is substantially comparable to the regulatory scheme applicable to the functionally equivalent U.S. institution(s). I also undertake to furnish to the Commission staff, upon request, information that would otherwise be disclosed in a Schedule 13D.

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Sofinnova Capital VIII
     
    Signature:/s/ Antoine Papiernik
    Name/Title:Antoine Papiernik / Managing Partner
    Date:04/30/2025
     
    Sofinnova Partners SAS, a French Corporation
     
    Signature:/s/ Antoine Papiernik
    Name/Title:Antoine Papiernik / Managing Partner
    Date:04/30/2025
     
    Antoine Papiernik
     
    Signature:/s/ Antoine Papiernik
    Name/Title:Antoine Papiernik
    Date:04/30/2025
     
    Henrijette Richter
     
    Signature:/s/ Henrijette Richter
    Name/Title:Henrijette Richter
    Date:04/30/2025
     
    Maina Bhaman
     
    Signature:/s/ Maina Bhaman
    Name/Title:Maina Bhaman
    Date:04/30/2025
     
    Graziano Seghezzi
     
    Signature:/s/ Graziano Seghezzi
    Name/Title:Graziano Seghezzi
    Date:04/30/2025
     
    Anta Gkelou
     
    Signature:/s/ Anta Gkelou
    Name/Title:Anta Gkelou
    Date:04/30/2025
     
    Karl Naegler
     
    Signature:/s/ Karl Naegler
    Name/Title:Karl Naegler
    Date:04/30/2025
    Exhibit Information

    Exhibit 1 - Joint Filing Agreement

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      5/13/25 8:00:00 AM ET
      $QNCX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Quince Therapeutics to Present at Citizens Life Sciences Conference

      Quince Therapeutics, Inc. (NASDAQ:QNCX), a late-stage biotechnology company dedicated to unlocking the power of a patient's own biology for the treatment of rare diseases, today announced that Dirk Thye, M.D., Quince's Chief Executive Officer and Chief Medical Officer, will present at the Citizens Life Sciences Conference taking place in New York City on Wednesday, May 7, 2025 beginning at 3:30 p.m. Eastern Time. A live webcast of the presentation will be accessible on the Events page under the News & Events heading of Quince's Investor Relations website at ir.quincetx.com. An archive of the webcast will be available shortly following the end of the live event. About Quince Therapeutics

      4/30/25 4:05:00 PM ET
      $QNCX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

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      11/14/24 4:00:05 PM ET
      $QNCX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
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      11/13/24 9:17:26 PM ET
      $QNCX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
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      $QNCX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

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      8-K - Quince Therapeutics, Inc. (0001662774) (Filer)

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      $QNCX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
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      10-Q - Quince Therapeutics, Inc. (0001662774) (Filer)

      5/13/25 8:40:57 AM ET
      $QNCX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
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      8-K - Quince Therapeutics, Inc. (0001662774) (Filer)

      5/13/25 8:01:26 AM ET
      $QNCX
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care