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    Amendment: SEC Form SCHEDULE 13G/A filed by Semler Scientific Inc.

    11/14/25 4:03:54 PM ET
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    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549


    SCHEDULE 13G


    UNDER THE SECURITIES EXCHANGE ACT OF 1934
    (Amendment No. 1)


    Semler Scientific, Inc.

    (Name of Issuer)


    Common stock, par value $0.001 per share

    (Title of Class of Securities)


    81684M104

    (CUSIP Number)


    09/30/2025

    (Date of Event Which Requires Filing of this Statement)


    Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
    Checkbox not checked   Rule 13d-1(b)
    Checkbox checked   Rule 13d-1(c)
    Checkbox not checked   Rule 13d-1(d)






    SCHEDULE 13G

    CUSIP No.
    81684M104


    1Names of Reporting Persons

    Ridgeback Capital Investments L.P.
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    0.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    0.0 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  The percentages used herein are calculated based upon 14,804,693 shares of common stock outstanding as of July 31, 2025, as reported by the Company in its Quarterly Report on Form 10-Q filed with the SEC on August 4, 2025.


    SCHEDULE 13G

    CUSIP No.
    81684M104


    1Names of Reporting Persons

    Ridgeback Capital Investments LLC
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    0.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    0.0 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  The percentages used herein are calculated based upon 14,804,693 shares of common stock outstanding as of July 31, 2025, as reported by the Company in its Quarterly Report on Form 10-Q filed with the SEC on August 4, 2025.


    SCHEDULE 13G

    CUSIP No.
    81684M104


    1Names of Reporting Persons

    Ridgeback Capital Management LLC
    2Check the appropriate box if a member of a Group (see instructions)

    Checkbox not checked  (a)
    Checkbox not checked  (b)
    3Sec Use Only
    4Citizenship or Place of Organization

    DELAWARE
    Number of Shares Beneficially Owned by Each Reporting Person With:
    5Sole Voting Power

    0.00
    6Shared Voting Power

    0.00
    7Sole Dispositive Power

    0.00
    8Shared Dispositive Power

    0.00
    9Aggregate Amount Beneficially Owned by Each Reporting Person

    0.00
    10Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

    Checkbox not checked
    11Percent of class represented by amount in row (9)

    0.0 %
    12Type of Reporting Person (See Instructions)

    OO

    Comment for Type of Reporting Person:  The percentages used herein are calculated based upon 14,804,693 shares of common stock outstanding as of July 31, 2025, as reported by the Company in its Quarterly Report on Form 10-Q filed with the SEC on August 4, 2025.


    SCHEDULE 13G

    Item 1. 
    (a)Name of issuer:

    Semler Scientific, Inc.
    (b)Address of issuer's principal executive offices:

    51 E. Campbell Ave., Suite 107-D, Campbell, CA, 95008
    Item 2. 
    (a)Name of person filing:

    This statement is filed on behalf of the following persons with respect to shares of common stock of the Company acquired by them (the "Shares"): (i) Ridgeback Capital Investments L.P., Delaware limited partnership ("RCILP"), with respect to Shares beneficially owned by it; (ii) Ridgeback Capital Investments LLC, a Delaware limited liability company ("RCI"), with respect to Shares beneficially owned by it; and (iii) Ridgeback Capital Management LLC, a Delaware limited liability company ("RCM"), with respect to Shares beneficially owned by it. The foregoing persons are hereinafter referred to collectively as the "Reporting Persons." Any disclosures herein with respect to persons other than the Reporting Persons are made on information and belief after making inquiry to the appropriate party. RCM and RCI do not own any Shares directly. RCI is the general partner of RCILP. Pursuant to an investment management agreement, RCM maintains investment and voting power with respect to the securities held or controlled by RCI. Wayne Holman, an individual, controls RCM. By reason of the provisions of Rule 13d-3 of the Securities Exchange Act of 1934, as amended, RCM and RCI may be deemed to own beneficially all of the Shares (constituting approximately 6.9% of the shares outstanding). Each of RCM and RCI disclaim beneficial ownership of any of the securities covered by this statement, except to the extent of any pecuniary interest therein.
    (b)Address or principal business office or, if none, residence:

    30 Star Island Drive, Miami, FL, 33139
    (c)Citizenship:

    RCILP is a Delaware limited partnership. RCI is a Delaware limited liability company. RCM is a Delaware limited liability company.
    (d)Title of class of securities:

    Common stock, par value $0.001 per share
    (e)CUSIP No.:

    81684M104
    Item 3.If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
    (a)Checkbox not checked   Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
    (b)Checkbox not checked   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
    (c)Checkbox not checked   Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
    (d)Checkbox not checked   Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
    (e)Checkbox not checked   An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
    (f)Checkbox not checked   An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
    (g)Checkbox not checked   A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
    (h)Checkbox not checked   A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
    (i)Checkbox not checked   A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
    (j)Checkbox not checked   A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
           please specify the type of institution:
    (k)Checkbox not checked   Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
     
    Item 4.Ownership
    (a)Amount beneficially owned:

    Ridgeback Capital Investments L.P.: -0- Ridgeback Capital Investments LLC: -0- Ridgeback Capital Management LLC: -0-
    (b)Percent of class:

    Ridgeback Capital Investments L.P.: 0.0% Ridgeback Capital Investments LLC: 0.0% Ridgeback Capital Management LLC: 0.0%
    (c)Number of shares as to which the person has:
     (i) Sole power to vote or to direct the vote:

    Ridgeback Capital Investments L.P.: -0- Ridgeback Capital Investments LLC: -0- Ridgeback Capital Management LLC: -0-

     (ii) Shared power to vote or to direct the vote:

    Ridgeback Capital Investments L.P.: -0- Ridgeback Capital Investments LLC: -0- Ridgeback Capital Management LLC: -0-

     (iii) Sole power to dispose or to direct the disposition of:

    Ridgeback Capital Investments L.P.: -0- Ridgeback Capital Investments LLC: -0- Ridgeback Capital Management LLC: -0-

     (iv) Shared power to dispose or to direct the disposition of:

    Ridgeback Capital Investments L.P.: -0- Ridgeback Capital Investments LLC: -0- Ridgeback Capital Management LLC: -0-

    Item 5.Ownership of 5 Percent or Less of a Class.
     
    Checkbox checked    Ownership of 5 percent or less of a class
    Item 6.Ownership of more than 5 Percent on Behalf of Another Person.
     
    Not Applicable
    Item 7.Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
     
    Not Applicable
    Item 8.Identification and Classification of Members of the Group.
     
    Not Applicable
    Item 9.Notice of Dissolution of Group.
     
    Not Applicable

    Item 10.Certifications:
     
    By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

        SIGNATURE 
     
    After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

     
    Ridgeback Capital Investments L.P.
     
    Signature:/s/ Nicole Venezia
    Name/Title:Nicole Venezia/General Counsel
    Date:11/14/2025
     
    Ridgeback Capital Investments LLC
     
    Signature:/s/ Nicole Venezia
    Name/Title:Nicole Venezia/General Counsel
    Date:11/14/2025
     
    Ridgeback Capital Management LLC
     
    Signature:/s/ Nicole Venezia
    Name/Title:Nicole Venezia/General Counsel
    Date:11/14/2025
    Exhibit Information

    Exhibit Number 99.1 - Joint Filing Agreement - previously filed

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