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    C4 Therapeutics Inc. filed SEC Form 8-K: Regulation FD Disclosure, Other Events, Financial Statements and Exhibits

    9/22/25 6:41:16 AM ET
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    Get the next $CCCC alert in real time by email
    cccc-20250922
    0001662579false00016625792025-09-222025-09-22

    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    WASHINGTON, D.C. 20549
    _________________________________________________________________
    FORM 8-K
    _________________________________________________________________
    CURRENT REPORT
    Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
    Date of Report (Date of earliest event reported): September 22, 2025 (September 20, 2025)
    _________________________________________________________________
    C4 THERAPEUTICS, INC.
    (Exact name of Registrant as Specified in Its Charter)
    _________________________________________________________________
    Delaware001-3956747-5617627
    (State or Other Jurisdiction
    of Incorporation)
    (Commission File Number)
    (IRS Employer
    Identification No.)
    490 Arsenal Way,   Suite 120
    Watertown,  MA
    02472
    (Address of Principal Executive Offices)(Zip Code)
    Registrant’s Telephone Number, Including Area Code: (617) 231-0700
    Not Applicable
    (Former Name or Former Address, if Changed Since Last Report)
    _________________________________________________________________
    Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
    oWritten communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
    oSoliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
    oPre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
    oPre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
    Securities registered pursuant to Section 12(b) of the Act:
    Title of each class
    Trading
    Symbol(s)
    Name of each exchange on which registered
    Common Stock, $0.0001 par value per shareCCCCThe Nasdaq Global Select Market
    Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).
    Emerging growth company o
    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o
     



    Item 7.01 Regulation FD Disclosure.
    On September 20, 2025, C4 Therapeutics, Inc. (the “Company”) issued a press release announcing data from its Phase 1 clinical trial of cemsidomide, an orally bioavailable IKZF1/3 degrader, in combination with dexamethasone for the treatment of relapsed/refractory multiple myeloma (“RRMM”), as presented in an oral presentation at the International Myeloma Society Annual Meeting (the "IMS Meeting"). A copy of the press release is being furnished as Exhibit 99.1 to this Current Report on Form 8-K.
    The information contained in Item 7.01 of this Current Report on Form 8-K and Exhibit 99.1 attached hereto is intended to be furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended (the “Securities Act”), or the Exchange Act, except as expressly set forth by specific reference in such a filing. The furnishing of this information hereby shall not be deemed an admission as to the materiality of any such information.
    Item 8.01 Other Events.
    On September 20, 2025, the Company presented data from its Phase 1 clinical trial of cemsidomide in combination with dexamethasone for the treatment of RRMM in an oral presentation at the IMS Meeting. A copy of the slides from this presentation, which has been published to the “Events & Presentations” page of the investor relations section of the Company’s website, is filed as Exhibit 99.2 to this Current Report on Form 8-K and incorporated herein by reference.
    Item 9.01 Financial Statements and Exhibits.
    (d) Exhibits. The exhibits shall be deemed to be filed or furnished, depending on the relevant item requiring such exhibit, in accordance with the provisions of Item 601 of Regulation S-K (17 CFR 229.601) and Instruction B.2 to this form.
    Exhibit
    Number
    Description
    99.1
    Press release issued September 20, 2025
    99.2
    Data presentation from International Myeloma Society Annual Meeting, dated September 20, 2025
    104Cover Page Interactive Data File (embedded within the Inline XBRL document)



    SIGNATURES
    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
    C4 Therapeutics, Inc.
    Date: September 22, 2025
    By:/s/ Jolie M. Siegel
    Jolie M. Siegel
    Chief Legal Officer and Secretary

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