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    Cortexyme downgraded by JMP Securities

    1/27/22 6:15:35 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $CRTX alert in real time by email
    JMP Securities downgraded Cortexyme from Mkt Outperform to Mkt Perform
    Get the next $CRTX alert in real time by email

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    Recent Analyst Ratings for
    $CRTX

    DatePrice TargetRatingAnalyst
    3/9/2022$30.00 → $15.00Buy
    HC Wainwright & Co.
    1/28/2022$75.00 → $12.00Buy → Hold
    Canaccord Genuity
    1/28/2022Buy → Hold
    Canaccord Genuity
    1/27/2022Mkt Outperform → Mkt Perform
    JMP Securities
    10/27/2021Neutral → Underperform
    B of A Securities
    10/27/2021$58.00 → $15.00Neutral → Underperform
    BofA Securities
    10/27/2021$200.00 → $30.00Buy
    HC Wainwright & Co.
    9/16/2021$75.00 → $150.00Buy
    Canaccord Genuity
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    $CRTX
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    HC Wainwright & Co. reiterated coverage on Cortexyme with a new price target

    HC Wainwright & Co. reiterated coverage of Cortexyme with a rating of Buy and set a new price target of $15.00 from $30.00 previously

    3/9/22 6:45:17 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Cortexyme downgraded by Canaccord Genuity with a new price target

    Canaccord Genuity downgraded Cortexyme from Buy to Hold and set a new price target of $12.00 from $75.00 previously

    1/28/22 7:19:09 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Cortexyme downgraded by Canaccord Genuity

    Canaccord Genuity downgraded Cortexyme from Buy to Hold

    1/28/22 6:06:43 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

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    Insider Trading

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    SEC Form 4: Monohon Ted covered exercise/tax liability with 1,640 shares, decreasing direct ownership by 5% to 29,311 units to cover taxes

    4 - Quince Therapeutics, Inc. (0001662774) (Issuer)

    12/7/22 5:37:47 PM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 4: Monohon Ted covered exercise/tax liability with 1,520 shares, decreasing direct ownership by 5% to 30,951 units to cover taxes

    4 - Quince Therapeutics, Inc. (0001662774) (Issuer)

    9/8/22 5:58:12 PM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 4 filed by Monohon Ted

    4 - Cortexyme, Inc. (0001662774) (Issuer)

    7/1/22 5:03:16 PM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

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    Cortexyme Corporate Name Change to Quince Therapeutics to Take Effect on August 1, 2022

    New ticker symbol (NASDAQ:QNCX) to initiate trading on August 1, 2022 Cortexyme, Inc. (NASDAQ:CRTX) today announced that the company's planned corporate name change to Quince Therapeutics is expected take effect on Monday, August 1, 2022. In conjunction with the corporate name change, the company plans to issue a news release that will provide a business update detailing Quince Therapeutics' go-forward growth strategy and development pipeline plans. Additionally, the company's ticker symbol on the Nasdaq Global Select Market is expected change to "QNCX" effective at the open of market trading on Monday, August 1, 2022. The company's common stock will continue to trade under the ticker sym

    7/27/22 8:01:00 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Cortexyme Successfully Completes Phase 1 Single and Multiple Ascending Dose Clinical Trial of COR588

    Once daily dose of COR588 over 10-day period well-tolerated with no serious adverse events observed Cortexyme, Inc. (NASDAQ:CRTX), a clinical-stage biopharmaceutical company focused on advancing therapeutics for rare and degenerative diseases, today reported the successful completion of its Phase 1 single ascending dose and multiple ascending dose (SAD/MAD) clinical trial of COR588, the company's lysine gingipain inhibitor in development for the treatment of Alzheimer's disease and indications with disease pathology associated with the keystone pathogen P. gingivalis. The study was a randomized, double-blind, placebo-controlled, first-in-human study to evaluate the safety, tolerability, an

    7/27/22 8:00:00 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
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    Cortexyme Announces Preclinical Data Demonstrating Efficacy of COR803 for the Treatment of Coronavirus Infections

    Cortexyme, Inc. (NASDAQ:CRTX), a clinical-stage biopharmaceutical company focused on advancing therapeutics for rare and degenerative diseases, today announced new preclinical data demonstrating the efficacy of the company's 3CLpro inhibitor, COR803, for treatment of coronavirus infections, including COVID-19 disease, caused by SARS-CoV-2 infection. In ongoing preclinical research, COR803 successfully reduced viral load of SARS-CoV-2 in vivo after oral treatment. COR803 is a novel small molecule 3CLpro inhibitor discovered and developed by Cortexyme based on its expertise in cysteine protease inhibition. 3CLpro, or Mpro, is a validated antiviral drug target shown to be essential in viral r

    6/21/22 8:00:00 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
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    $CRTX
    SEC Filings

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    Cortexyme Inc. filed SEC Form 8-K: Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

    8-K - Quince Therapeutics, Inc. (0001662774) (Filer)

    12/16/22 4:04:17 PM ET
    $CRTX
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    SEC Form 10-Q filed by Cortexyme Inc.

    10-Q - Quince Therapeutics, Inc. (0001662774) (Filer)

    11/9/22 4:17:03 PM ET
    $CRTX
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    Cortexyme Inc. filed SEC Form 8-K: Leadership Update

    8-K - Quince Therapeutics, Inc. (0001662774) (Filer)

    9/30/22 5:08:03 PM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
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    Cortexyme Reports GAIN Trial Data Demonstrated Relationship Between Reduction of P. gingivalis Infection and Slowing of Alzheimer's Disease Progression

    In overall population, co-primary endpoints of ADAS-Cog11 and ADCS-ADL were not met Pre-specified subgroups representing up to half of the participants based on P. gingivalis infection level showed approximately 50% slowing of cognitive decline Clinical data validated upstream mechanism of action and benefits of targeting P. gingivalis Additional top-line GAIN Trial results to be presented at CTAD 2021 on November 11th Cortexyme to host investor conference call today Tuesday, October 26th at 4:30 p.m. Eastern Time Cortexyme, Inc. (NASDAQ:CRTX) today reported top-line results from its Phase 2/3 GAIN Trial, a double-blind, placebo-controlled study evaluating the efficacy of atuzaginstat

    10/26/21 4:01:00 PM ET
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    Cortexyme Appoints June Bray to its Board of Directors

    Cortexyme, Inc. (NASDAQ:CRTX), a clinical-stage biopharmaceutical company focused on rare and degenerative diseases, today announced the appointment of June Bray, a pharmaceutical industry veteran and global drug development and regulatory process expert, to the company's Board of Directors. "We are very pleased to welcome a seasoned pharmaceutical and global regulatory expert of June Bray's caliber to our Board of Directors," said David Lamond, chairperson of Cortexyme's Board of Directors. "With more than four decades of pharmaceutical industry experience, we look forward to her valuable contribution and perspective across multiple therapeutic areas." "I am excited to join Cortexyme's B

    6/13/22 8:00:00 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Cortexyme Appoints Dr. Philip Low to Its Board of Directors

    Cortexyme, Inc. (NASDAQ:CRTX), a clinical-stage biopharmaceutical company pioneering therapeutic approaches to improve the lives of patients diagnosed with degenerative diseases, today announced the appointment of Dr. Philip S. Low, a renowned targeted drug discovery researcher and veteran biotech entrepreneur, to the company's Board of Directors. "In conjunction with today's acquisition of Novosteo, we are very pleased to welcome a distinguished researcher, innovator, and entrepreneur of Dr. Philip Low's caliber to our Board of Directors," said David Lamond, chairman of Cortexyme's Board of Directors. "His vast expertise across targeted drug discovery, prolific research abilities, and pro

    5/20/22 8:01:00 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
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    Cortexyme Announces Agreement to Acquire Novosteo

    Expanding pipeline with addition of targeted therapeutics to treat rare skeletal diseases, bone cancer and injury Strengthening leadership team with appointment of Novosteo executives Dr. Dirk Thye as CEO and Dr. Karen Smith as CMO of combined company Planning corporate name change to Quince Therapeutics to reflect broadening of therapeutic pipeline Cortexyme, Inc. (NASDAQ:CRTX), a clinical-stage biopharmaceutical company dedicated to improving the lives of patients diagnosed with degenerative diseases, today announced that it entered into an agreement under which the company plans to acquire Novosteo, a privately-held biotech company focused on targeted therapeutics to treat rare skelet

    5/10/22 8:00:00 AM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
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    SEC Form SC 13G/A filed by Cortexyme Inc. (Amendment)

    SC 13G/A - Cortexyme, Inc. (0001662774) (Subject)

    7/8/22 12:56:11 PM ET
    $CRTX
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    SEC Form SC 13G/A filed by Cortexyme Inc. (Amendment)

    SC 13G/A - Cortexyme, Inc. (0001662774) (Subject)

    2/11/22 2:48:42 PM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
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    SEC Form SC 13G/A filed by Cortexyme Inc. (Amendment)

    SC 13G/A - Cortexyme, Inc. (0001662774) (Subject)

    2/11/22 12:22:48 PM ET
    $CRTX
    Biotechnology: Biological Products (No Diagnostic Substances)
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