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    CRISPR Therapeutics AG filed SEC Form 8-K: Leadership Update, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Submission of Matters to a Vote of Security Holders, Financial Statements and Exhibits

    6/3/24 8:06:56 AM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $CRSP alert in real time by email
    8-K
    --12-310001674416false00-000000000016744162024-05-302024-05-30

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    WASHINGTON, D.C. 20549

     

    FORM 8-K

     

    CURRENT REPORT

    Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

    Date of Report (Date of earliest event reported): May 30, 2024

     

    CRISPR THERAPEUTICS AG

    (Exact name of Registrant as Specified in Its Charter)

     

     

    Switzerland

    001-37923

    Not Applicable

    (State or Other Jurisdiction

    of Incorporation)

    (Commission File Number)

    (IRS Employer

    Identification No.)

     

     

     

    Baarerstrasse 14

    6300 Zug, Switzerland

    Not Applicable

    (Address of Principal Executive Offices)

    (Zip Code)

     

    Registrant’s Telephone Number, Including Area Code: +41 (0)41 561 32 77

    Not Applicable

    (Former Name or Former Address, if Changed Since Last Report)

     

    Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

     

    ☐

    Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

    ☐

    Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

    ☐

    Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

    ☐

    Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

    Securities registered pursuant to Section 12(b) of the Act:

     

    Title of each class

     

    Trading Symbol(s)

     

    Name of each exchange on which registered

    Common Shares, nominal value CHF 0.03

     

    CRSP

     

    The Nasdaq Global Market

     

    Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

    Emerging growth company ☐

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

     


     

     


     

    Item 5.02.

    Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

    Approval of Amendment to CRISPR Therapeutics AG 2018 Stock Option and Incentive Plan

    On May 30, 2024, at the 2024 Annual General Meeting of Shareholders (the “Annual Meeting”), the shareholders of CRISPR Therapeutics AG (the “Company”) approved the amendment (the “Plan Amendment”) to the CRISPR Therapeutics AG 2018 Stock Option and Incentive Plan (the “2018 Plan”) to increase the number of common shares, par value CHF 0.03 per share (“Common Shares”) reserved for issuance under the 2018 Plan by 1,000,000 Common Shares and to increase the number of shares that may be issued in the form of incentive stock options by 1,000,000 Common Shares. The Plan Amendment previously had been approved, subject to shareholder approval, by the Company’s Board of Directors.

    The Company’s officers and directors are among the persons eligible to receive awards under the 2018 Plan, as amended, in accordance with the terms and conditions thereunder. A detailed summary of the 2018 Plan and the Plan Amendment is set forth in the Company’s proxy statement for the Annual Meeting filed with the Securities and Exchange Commission on April 9, 2024 (the “Proxy Statement”) under the caption “Proposal 9: Approval of Amendment to the CRISPR Therapeutics AG 2018 Stock Option and Incentive Plan”, which summary is incorporated herein by reference. That detailed summary of the 2018 Plan and Plan Amendment, and the foregoing description of the Plan Amendment, are qualified in their entirety by reference to (i) the full text of the 2018 Plan, which is filed as Exhibit 99.1 to the Company’s Registration Statement on Form S-8 filed on June 1, 2018, (ii) the full text of Amendment No. 1 to the 2018 Stock Option and Incentive Plan, which is attached as Appendix A to the Company’s Definitive Proxy Statement on Schedule 14A filed on April 30, 2019, (iii) the full text of Amendment No. 2 to the 2018 Stock Option and Incentive Plan, which is attached as Appendix A to the Company’s Definitive Proxy Statement on Schedule 14A filed on April 24, 2020, (iv) the full text of Amendment No. 3 to the 2018 Stock Option and Incentive Plan, which is attached as Appendix A to the Company’s Definitive Proxy Statement on Schedule 14A filed on April 25, 2022, (v) the full text of Amendment No. 4 to the 2018 Stock Option and Incentive Plan, which is attached as Appendix B to the Company’s Definitive Proxy Statement on Schedule 14A filed on April 26, 2023, and (vi) the full text of the Plan Amendment, a copy of which is attached as Appendix A to the Proxy Statement, and in each case, incorporated herein by reference.

     

    Item 5.03.

    Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year

    At the Annual Meeting, the Company’s shareholders approved amendments to the articles of association of the Company (the “Articles of Association”) as described in the Proxy Statement. The Company’s amended and restated Articles of Association become effective upon registration in the Commercial Register in the canton of Zug, Switzerland on or about May 31, 2024, subject to the approval by the Swiss Federal Commercial Authority. A copy of the amended and restated Articles of Association is attached hereto as Exhibit 3.1 and incorporated herein by reference.

    Item 5.07.

    Submission of Matters to a Vote of Security Holders

    The Annual Meeting was held on May 30, 2024. Proxies were solicited pursuant to the Proxy Statement.

    At the Annual Meeting, the Company’s shareholders were asked (i) to approve the Swiss management report, the consolidated financial statements and the statutory financial statements of the Company for the year ended December 31, 2023, (ii) to approve the appropriation of financial results, (iii) to discharge the members of the Company’s Board of Directors and Executive Committee, (iv) to elect or re-elect nine members and the chairman to the Company’s Board of Directors, (v) to re-elect four members of the Compensation Committee of the Board of Directors, (vi) to approve the compensation for the Board of Directors and the Executive Committee and, on a non-binding basis, the Swiss statutory compensation report of the Company for the year ended December 31, 2023 (the “2023 Compensation Report”), (vii) to approve, on a non-binding basis, the compensation paid to the Company’s named executive officers under U.S. securities law requirements, (viii) to approve an increase in the conditional share capital for the Company’s employee equity plans, (ix) to approve the Plan Amendment, (x) to approve

     


     

    amendments to the Articles of Association to facilitate the use of equity compensation and pension benefits programs consistent with current market practices; (xi) to approve an increase and certain adjustments to the Company’s capital band; (xii) to re-elect the independent voting rights representative, (xiii) to re-elect Ernst & Young AG as the Company’s statutory auditor and to re-elect Ernst & Young LLP as the Company’s independent registered public accounting firm for the year ending December 31, 2024, and (xiv) to approve the transaction of any other business that may properly come before the Annual Meeting.

    The voting results reported below are final.

    Proposal 1 – Approval of the Swiss Management Report, the Consolidated Financial Statements and the Statutory Financial Statements of the Company for the Year Ended December 31, 2023

    The Swiss management report, the consolidated financial statements and the statutory financial statements of the Company for the year ended December 31, 2023 were approved. The results of the vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    60,823,544

     

    226,925

     

    244,210

     

    0

    Proposal 2 – Approval of the Appropriation of Financial Results

    The proposal to carry forward the net income resulting from the appropriation of financial results was approved. The results of the vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    60,715,908

     

    283,326

     

    295,445

     

    0

    Proposal 3 – Discharge of the Members of the Company's Board of Directors and Executive Committee

    The discharge of the members of the Company’s Board of Directors and the Executive Committee from personal liability for their activities during the year ended December 31, 2023 was approved. The results of the vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    42,727,165

     

    171,815

     

    123,325

     

    18,272,374

    Proposal 4 –Election or Re-election of the Members and Chair of the Board of Directors

    Samarth Kulkarni, Ph.D., Ali Behbahani, M.D., Maria Fardis, Ph.D., H. Edward Fleming Jr., M.D., Simeon J. George, M.D., John T. Greene, Katherine A. High, M.D., and Douglas A. Treco, Ph.D. were each duly re-elected as members of the Company’s Board of Directors, Samarth Kulkarni, Ph.D. was duly re-elected as the chairman of the Company’s Board of Directors, and Sandesh Mahatme, LL.M. and Christian Rommel, Ph.D., were duly elected as members of the Company’s Board of Directors. The results of the election were as follows:

    NOMINEE

    FOR

    AGAINST

    ABSTAIN

    BROKER

    NON-VOTES

    Samarth Kulkarni, Ph.D.

    42,442,977

    503,265

    76,063

    18,272,374

    Ali Behbahani, M.D.

    28,820,247

    14,118,172

    83,886

    18,272,374

    Maria Fardis, Ph.D.

    42,253,383

    689,281

    79,641

     

    18,272,374

    H Edward Fleming Jr., M.D.

    35,393,629

     

    7,547,609

     

    81,067

     

    18,272,374

    Simeon J. George, M.D.

    33,809,769

     

    9,131,338

     

    81,198

     

    18,272,374

    John T. Greene

    34,903,054

     

    8,038,359

     

    80,892

     

    18,272,374

    Katherine A. High, M.D.

    42,672,595

     

    274,928

     

    74,782

     

    18,272,374

    Douglas A. Treco, Ph.D.

    40,807,871

     

    2,133,551

     

    80,883

     

    18,272,374

    Sandesh Mahatme, LL.M.

    42,762,070

     

    177,633

     

    82,602

     

    18,272,374

    Christian Rommel, Ph.D.

     

    42,777,061

     

    162,398

     

    82,846

     

    18,272,374

     

     


     

    Proposal 5 –Re-election of the Members of the Compensation Committee

    Ali Behbahani, M.D., H. Edward Fleming, Jr., M.D., Simeon J. George, M.D., and John T. Greene were each duly re-elected as members of the Company’s Compensation Committee of the Board of Directors. The results of the election were as follows:

    NOMINEE

    FOR

    AGAINST

    ABSTAIN

    BROKER

    NON-VOTES

    Ali Behbahani, M.D.

    28,182,970

     

    14,734,499

     

    104,836

     

    18,272,374

    H Edward Fleming Jr., M.D.

    34,866,314

     

    8,048,771

     

    107,220

     

    18,272,374

    Simeon J. George, M.D.

    32,981,270

     

    9,932,010

     

    109,025

     

    18,272,374

    John T. Greene

    34,374,439

     

    8,540,932

     

    106,934

     

    18,272,374

    Proposal 6 – Approval of the Compensation for the Board of Directors and the Executive Committee and 2023 Compensation Report

    The total non-performance-related compensation for members of the Board of Directors from the Annual Meeting to the 2025 annual general meeting of shareholders was approved on a binding basis. The results of the binding vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    42,404,960

     

    483,779

     

    133,566

     

    18,272,374

    The grant of equity for members of the Board of Directors from the Annual Meeting to the 2025 annual general meeting of shareholders was approved on a binding basis. The results of the binding vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    32,217,566

     

    10,666,594

     

    138,145

     

    18,272,374

     

    The total non-performance related compensation for members of the Executive Committee from July 1, 2024 to June 30, 2025 was approved on a binding basis. The results of the binding vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    34,292,605

     

    8,596,024

     

    133,676

     

    18,272,374

    The total variable compensation for members of the Executive Committee for the current year ending December 31, 2024 was approved on a binding basis. The results of the binding vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    34,265,938

     

    8,620,448

     

    135,919

     

    18,272,374

    The grant of equity for members of the Executive Committee from the Annual Meeting to the 2025 annual general meeting of shareholders was approved on a binding basis. The results of the binding vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    32,216,984

     

    10,658,861

     

    146,460

     

    18,272,374

    The endorsement of the 2023 Compensation Report was approved on a non-binding basis. The results of the non-binding vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    32,163,571

     

    10,698,220

     

    160,514

     

    18,272,374

     

     


     

    Proposal 7 – Non-Binding Advisory Vote on the Compensation Paid to Named Executive Officers Under U.S. Securities Law Requirements

    The compensation paid to the named executive officers was approved on a non-binding basis. The results of the non-binding vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    32,094,737

     

    10,778,822

     

    148,746

     

    18,272,374

    Proposal 8 – Approval of an Increase in the Conditional Share Capital for Employee Equity Plans

    An increase in the Company’s conditional share capital for employee equity plans was approved with at least two thirds of the votes represented and the absolute majority of the par value of the represented shares. The results of the vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    32,512,494

     

    10,394,452

     

    115,359

     

    18,272,374

    Proposal 9 – Approval of Amendment to the 2018 Stock Option and Incentive Plan

    The Plan Amendment was approved. The results of the vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    34,337,953

     

    8,532,315

     

    152,037

     

    18,272,374

    Proposal 10 – Approval of Amendments to the Articles of Association to Facilitate the Use of Equity Compensation and Pension Benefits Programs Consistent with Current Market Practices

    Amendment and restatement of 18, 32, 33, 40 and 41 of the Articles of Association to align the Company’s use of equity compensation and pension benefits programs with evolving Swiss legal trends and current market practices including, without limitation, permitting the Company to use common shares, stock options, restricted stock units and other similar instruments as equity incentive compensation under the Company’s various equity incentive plans including the 2018 Plan and a more flexible use of international pension benefit plans, was approved. The results of the vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    33,909,689

     

    8,995,908

     

    116,708

     

    18,272,374

    Proposal 11 – Approval of an Increase and Certain Adjustments to the Company’s Capital Band

    Amendment of art. 3a of the Articles of Association to increase the Company’s capital band to the upper limit of CHF 3,100,452.06 and amendment and restatement of art. 3a, para. 1 of the Articles of Association to make certain ministerial changes to such paragraph, were approved with at least two thirds of the votes represented and the absolute majority of the par value of the represented shares. The results of the vote were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    58,625,938

     

    2,209,165

     

    459,576

     

    0

    Proposal 12 – Re-election of the Independent Voting Rights Representative

    Marius Meier, Attorney at Law, was duly re-elected as the independent voting rights representative. The results of the election were as follows:

     


     

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    60,444,538

     

    555,381

     

    294,760

     

     

     

    Proposal 13 – Re-election of the Auditors

    Ernst & Young AG was duly elected as the Company’s statutory auditor for the term of office of one year, and Ernst & Young LLP was duly elected as the Company’s independent registered public accounting firm for the year ending December 31, 2024. The results of the election were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    60,337,355

     

    352,399

     

    604,925

     

    0

    Proposal 14 – Transaction of Any Other Business

    The proposal for the transaction of any other business that properly came before the Annual Meeting or any adjournment or postponement thereof, to follow the respective proposal of the Board of Directors as proposed at the Annual Meeting, was not approved. The results of the election were as follows:

     

     

    FOR

     

    AGAINST

     

    ABSTAIN

     

    BROKER

    NON-VOTES

    NUMBER

     

    20,311,835

     

    21,901,628

     

    808,842

     

    18,272,374

     

     


     

    Item 9.01

    Financial Statements and Exhibits

    (d) Exhibits

    Exhibit
    Number

     

    Description

     

     

     

    3.1*

     

    Amended and Restated Articles of Association of CRISPR Therapeutics AG

     

     

     

    10.1#

     

    CRISPR Therapeutics AG 2018 Stock Option and Incentive Plan and forms of agreements thereunder (incorporated herein by reference to Exhibit 99.1 to the Company’s Registration Statement on Form S-8 filed on June 1, 2018).

     

     

     

    10.2#

     

    Amendment No. 1 to the 2018 Stock Option and Incentive Plan (incorporated herein by reference to Appendix A to the Company’s Definitive Proxy Statement on Schedule 14A filed on April 30, 2019).

     

     

     

    10.3#

     

    Amendment No. 2 to the 2018 Stock Option and Incentive Plan (incorporated herein by reference to Appendix A to the Company’s Definitive Proxy Statement on Schedule 14A filed on April 24, 2020).

     

     

     

    10.4#

     

    Amendment No. 3 to the 2018 Stock Option and Incentive Plan (incorporated herein by reference to Appendix A to the Company’s Definitive Proxy Statement on Schedule 14A filed on April 25, 2022).

     

     

     

    10.5#

     

    Amendment No. 4 to the 2018 Stock Option and Incentive Plan (incorporated herein by reference to Appendix A to the Company’s Definitive Proxy Statement on Schedule 14A filed on April 26, 2023).

     

     

     

    10.6#

     

    Amendment No. 5 to the 2018 Stock Option and Incentive Plan (incorporated herein by reference to Appendix A to the Company’s Definitive Proxy Statement on Schedule 14A filed on April 9, 2024).

    104

     

    Cover Page Interactive Data File (embedded within the Inline XBRL document)

     

    * Filed herewith.

    # A management contract or compensatory plan or arrangement required to be filed as an exhibit pursuant to Item 15(a)(3) of Form 10-K

     


     

    SIGNATURES

    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

     

     

     

     

     

     

     

     

    CRISPR THERAPEUTICS AG

     

     

     

     

    Date: June 3, 2024

     

    By:

    /s/ Samarth Kulkarni

     

     

     

    Samarth Kulkarni, Ph.D.

     

     

     

    Chief Executive Officer

     

     


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    Legendary Investors are Rotating Capital into AI Powered Biotech

    DENVER, March 30, 2026 (GLOBE NEWSWIRE) -- Cathie Wood and ARK Invest are making a decisive pivot that signals where the next phase of artificial intelligence value creation may emerge: healthcare. In a series of trades during late March, Wood aggressively reduced exposure to mega-cap technology and semiconductor names while building a high-conviction position in Tempus AI (NASDAQ:TEM). The move reflects a broader thesis she has increasingly emphasized, the most underestimated frontier for AI innovation is healthcare. As AI infrastructure becomes crowded and capital-intensive, ARK is rotating toward companies applying AI to real-world, high-stakes problems like disease detection, drug deve

    3/30/26 9:15:00 AM ET
    $CRSP
    $META
    $TEM
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Computer Software: Programming Data Processing
    Technology

    CRISPR Therapeutics Prices Upsized Convertible Senior Notes Offering

    ZUG, Switzerland and BOSTON, March 11, 2026 (GLOBE NEWSWIRE) -- CRISPR Therapeutics AG (NASDAQ:CRSP) (the "Company") today announced the pricing of $550 million aggregate principal amount of its convertible senior notes due 2031 (the "notes") in a private offering (the "offering") to persons reasonably believed to be qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended (the "Securities Act"). The Company also granted the initial purchasers of the notes an option to purchase, for settlement within a period of 13 days from, and including, the date the notes are first issued, up to an additional $50 million aggregate principal amount of the notes.

    3/11/26 7:00:00 AM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    CRISPR Therapeutics Announces Proposed Convertible Senior Notes Offering

    ZUG, Switzerland and BOSTON, March 10, 2026 (GLOBE NEWSWIRE) -- CRISPR Therapeutics AG (NASDAQ:CRSP) (the "Company") today announced its intention to offer, subject to market conditions and other factors, $350 million aggregate principal amount of its convertible senior notes due 2031 (the "notes") in a private offering (the "offering") to persons reasonably believed to be qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended (the "Securities Act"). The Company also expects to grant the initial purchasers of the notes an option to purchase, for settlement within a period of 13 days from, and including, the date the notes are first issued, up to a

    3/10/26 7:00:00 AM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $CRSP
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    Analyst initiated coverage on CRISPR Therapeutics with a new price target

    Analyst initiated coverage of CRISPR Therapeutics with a rating of Overweight and set a new price target of $70.00

    9/18/25 8:39:47 AM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    CRISPR Therapeutics upgraded by Evercore ISI with a new price target

    Evercore ISI upgraded CRISPR Therapeutics from In-line to Outperform and set a new price target of $99.00 from $60.00 previously

    2/14/25 8:06:15 AM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    CRISPR Therapeutics upgraded by TD Cowen with a new price target

    TD Cowen upgraded CRISPR Therapeutics from Sell to Hold and set a new price target of $35.00

    2/12/25 7:01:19 AM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $CRSP
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    CRISPR Therapeutics Proposes New Appointment to the Board of Directors

    ZUG, Switzerland and BOSTON, Jan. 07, 2025 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (NASDAQ:CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, today announced it proposes to elect Briggs Morrison, M.D., to its Board of Directors at the Company's annual general meeting to be held this year. "We are excited to welcome Briggs to our Board of Directors," said Samarth Kulkarni, Ph.D., Chief Executive Officer and Chairman of the Board of CRISPR Therapeutics. "His extensive experience in the pharmaceutical industry and expertise in clinical development will be a tremendous asset as we continue to advance our innovative platform and pip

    1/7/25 8:00:00 AM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    CRISPR Therapeutics Strengthens Executive Leadership Team with Key Appointments

    -Naimish Patel, M.D., appointed to Chief Medical Officer- -Julianne Bruno, M.B.A., promoted to Chief Operating Officer- ZUG, Switzerland and BOSTON, May 23, 2024 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (NASDAQ:CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, today announced the appointment of Naimish Patel, M.D., as Chief Medical Officer, effective May 28, 2024. Dr. Patel is an experienced drug developer who has worked across a wide range of disease areas, including his most recent leadership role as the Global Development Therapeutic Area Head of Immunology and Inflammation at Sanofi. In addition, the Company al

    5/23/24 8:00:00 AM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    CRISPR Therapeutics Announces Transition of Chief Financial Officer

    ZUG, Switzerland and BOSTON, March 13, 2023 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (NASDAQ:CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, announces the hiring and appointment of Raju Prasad, Ph.D., as Chief Financial Officer, effective March 14, 2023. He joins CRISPR Therapeutics from William Blair & Company, where he served as a Partner and Senior Equity Research Analyst covering cell therapy, gene therapy, and gene editing companies. Dr. Prasad succeeds Brendan Smith, who is leaving the Company to pursue external opportunities. "I'm excited to welcome Raju to our leadership team," said Samarth Kulkarni, Ph.D., Chief Exec

    3/13/23 4:15:00 PM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $CRSP
    Large Ownership Changes

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    Amendment: SEC Form SC 13G/A filed by CRISPR Therapeutics AG

    SC 13G/A - CRISPR Therapeutics AG (0001674416) (Subject)

    12/10/24 1:34:45 PM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form SC 13G/A filed by CRISPR Therapeutics AG (Amendment)

    SC 13G/A - CRISPR Therapeutics AG (0001674416) (Subject)

    4/10/24 11:58:51 AM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form SC 13G/A filed by CRISPR Therapeutics AG (Amendment)

    SC 13G/A - CRISPR Therapeutics AG (0001674416) (Subject)

    2/12/24 6:22:35 PM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $CRSP
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    CRISPR Therapeutics Reports Positive Results from its Phase 1 CARBON Trial of CTX110™ in Relapsed or Refractory CD19+ B-cell malignancies

    -58% overall response rate (ORR) and 38% complete response (CR) rate in large B-cell lymphoma (LBCL) with a single dose of CTX110 at Dose Level 2 (DL2) and above on an intent-to-treat (ITT) basis- -Durable responses in LBCL achieved with six-month CR rate of 21% and longest response on-going at over 18 months after initial infusion- -Response rates and durability are similar to approved autologous CD19 CAR-T therapies on an ITT basis- -Positively differentiated safety profile; no Grade 3 or higher cytokine release syndrome (CRS) and low rates of infection and Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS)- -Expanding CARBON into a potentially registrational trial in 1Q 20

    10/12/21 4:01:00 PM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    CRISPR Therapeutics to Host Virtual Event Highlighting CTX110™ Clinical Data

    -Management to host conference call and webcast on October 12th at 4:30 p.m. ET- ZUG, Switzerland and CAMBRIDGE, Mass., Oct. 05, 2021 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (NASDAQ:CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious diseases, today announced that management will host a virtual event on October 12, 2021 at 4:30 p.m. ET to highlight clinical data from its ongoing Phase 1 CARBON trial assessing the safety and efficacy of CTX110, its wholly-owned allogeneic chimeric antigen receptor T cell (CAR-T) investigational therapy targeting CD19, for the treatment of relapsed or refractory B-cell malignancies. Conference Call and Web

    10/5/21 4:05:00 PM ET
    $CRSP
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care