• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
PublishGo to AppAI Superconnector
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEW
    Legal
    Terms of usePrivacy policyCookie policy

    Cyclerion Therapeutics Enters into Exclusive Negotiation Period and Binding Equity Investment Agreement

    4/3/23 7:30:00 AM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $CYCN alert in real time by email

    CAMBRIDGE, Mass., April 03, 2023 (GLOBE NEWSWIRE) -- Cyclerion Therapeutics, Inc. (NASDAQ:CYCN) today announced that the Board of Directors of the Company, acting solely by all of its independent and disinterested members (the "Independent Board"), has reviewed a non-binding proposal received on March 17, 2023 from an entity formed by investors that include the Company's Chief Executive Officer (CEO), to purchase the Company's zagociguat and CY3018 assets. After consultation with its legal and financial advisors, the Independent Board has concluded that the proposal merits further pursuit. Cyclerion has entered an exclusive negotiation arrangement for a limited period to allow the parties to negotiate binding documentation.

    In addition, Cyclerion has entered into a binding agreement with CEO Peter Hecht for him to make an equity investment in Cyclerion of $5M in cash for common stock or nonvoting convertible preferred stock of Cyclerion, the purchase price, consistent with Nasdaq rules, to be at or above the market price at the time of signing that agreement. The closing of the equity investment is contingent upon negotiation and completion of definitive documentation associated with the above transaction and would take place six business days after the signing of these documents. The proceeds are intended to support ongoing operations.

    The transaction remains subject to approvals by the Board of Directors and Cyclerion shareholders. There can be no assurances that any agreement will be reached or that a transaction will be agreed upon or completed on the terms set forth above or otherwise. The Company does not plan to provide further comment until an agreement is reached or the discussions are terminated.

    About Cyclerion Therapeutics

    Cyclerion Therapeutics is a clinical-stage biopharmaceutical company on a mission to develop treatments for serious diseases. Cyclerion's portfolio includes novel sGC stimulators that modulate a key node in a fundamental signaling network in both the CNS and the periphery. The multidimensional pharmacology elicited by the stimulation of sGC has the potential to impact a broad range of diseases. Zagociguat is a CNS-penetrant sGC stimulator that has shown rapid improvements across a range of endpoints reflecting multiple domains of disease activity, including mitochondrial disease-associated biomarkers. CY3018 is a CNS-targeted sGC stimulator in preclinical development that preferentially localizes to the brain and has a pharmacology profile that suggests its potential for the treatment of neuropsychiatric diseases and disorders. Praliciguat is a systemic sGC stimulator that is licensed to Akebia and being advanced in rare kidney disease. Olinciguat is a vascular sGC stimulator that the Company intends to out-license for cardiovascular diseases. For more information about Cyclerion, please visit https://www.cyclerion.com/ and follow us on Twitter (@Cyclerion) and LinkedIn (www.linkedin.com/company/cyclerion).

    Forward Looking Statement

    Certain matters discussed in this press release are "forward-looking statements". We may, in some cases, use terms such as "predicts," "believes," "potential," "continue," "estimates," "anticipates," "expects," "plans," "intends," "may," "could," "might," "will," "should", "positive" or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. The forward-looking statements include risks and uncertainties, including, but not limited to, the Company may never successfully negotiate or completing any binding documentation associated with the referenced transactions; if completed, the referenced transactions may not be successful or sufficient to advance the Company's operational plans as currently proposed; regardless whether the Company were to complete the referenced transactions, there can be no assurances that the Company will succeed with any operational plan under current circumstances; being able to complete clinical studies for zagociguat for the treatment of mitochondrial diseases, including submitting additional regulatory applications in other countries; ability to demonstrate effectiveness of zagociguat in treating mitochondrial disease in patients; ability to maintain and expand related intellectual property portfolio; and statements regarding the timing of regulatory filings regarding development programs. The factors discussed herein could cause actual results and developments to be materially different from those expressed in or implied by such statements. The forward-looking statements are made only as of the date of this press release and the Company undertakes no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstance.

    Investors and Media Inquiries

    Cyclerion Investor Relations

    Phone: 857-327-8778

    Email: [email protected]



    Primary Logo

    Get the next $CYCN alert in real time by email

    Crush Q3 2025 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $CYCN

    DatePrice TargetRatingAnalyst
    10/20/2021$14.00Buy
    Truist Securities
    9/24/2021$7.00Overweight
    Cantor Fitzgerald
    More analyst ratings

    $CYCN
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Truist Securities initiated coverage on Cyclerion Therapeutics with a new price target

    Truist Securities initiated coverage of Cyclerion Therapeutics with a rating of Buy and set a new price target of $14.00

    10/20/21 7:03:08 AM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Cantor Fitzgerald initiated coverage on Cyclerion Therapeutics with a new price target

    Cantor Fitzgerald initiated coverage of Cyclerion Therapeutics with a rating of Overweight and set a new price target of $7.00

    9/24/21 7:19:43 AM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CYCN
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    Cyclerion's sGC Stimulator Portfolio Generates Revenues to Enable Company Growth

    CAMBRIDGE, Mass., Dec. 17, 2024 (GLOBE NEWSWIRE) -- Cyclerion Therapeutics, Inc. (NASDAQ:CYCN), today announced an update on its progress in catalyzing the Company's next stage of growth. The Company is leveraging its legacy soluble guanylate cyclase (sGC) stimulator assets to generate near-term revenues which will be used to implement its strategic building plan without near-term dilution. "These agreements demonstrate Cyclerion's progress in maximizing its legacy asset value while redirecting resources toward acquiring potential new assets," said Regina Graul, Ph.D., President and Chief Executive Officer of Cyclerion. "These newly finalized agreements, combined with our significant redu

    12/17/24 8:08:11 AM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Regina Graul, Ph.D., Promoted to Chief Executive Officer

    CAMBRIDGE, Mass., Aug. 07, 2024 (GLOBE NEWSWIRE) -- Cyclerion Therapeutics, Inc. (NASDAQ:CYCN), today announced that Regina Graul, Ph.D., has been promoted to Chief Executive Officer, President, and member of the Board of Directors. Since Dr. Graul joined Cyclerion as President in early December 2023, she has strengthened all aspects of the company. She has been working closely with the Board of Directors to prioritize building shareholder value by reducing Cyclerion's operating costs while leading a world-class search and evaluation team, currently triaging multiple business development prospects for which Cyclerion believes it is well suited. "From the day Regina arrived at Cyclerio

    8/7/24 7:00:00 AM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Cyclerion Appoints Regina Graul, Ph.D., as President

    – Dr. Graul will lead the rebuild of Cyclerion, bringing more than two decades of drug making experience, R&D portfolio leadership, and a deep expertise in company strategy – – Peter Hecht, Ph.D., will continue to work closely with Cyclerion leadership as a strategic consultant and longstanding board member; steps down from CEO role – CAMBRIDGE, Mass., Dec. 04, 2023 (GLOBE NEWSWIRE) -- Cyclerion Therapeutics, Inc. (NASDAQ:CYCN), a biopharmaceutical company on a mission to develop treatments for serious diseases, today announced that Regina Graul, Ph.D., has joined the company as president, effective immediately. As Cyclerion's president, she will lead the organization and will work close

    12/4/23 8:00:00 AM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CYCN
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    SEC Form 4 filed by Chief Financial Officer Chicko Rhonda M.

    4 - Cyclerion Therapeutics, Inc. (0001755237) (Issuer)

    8/11/25 4:05:06 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Director Hecht Peter M was granted 181,818 shares, increasing direct ownership by 48% to 559,203 units (SEC Form 4)

    4 - Cyclerion Therapeutics, Inc. (0001755237) (Issuer)

    3/27/25 8:38:03 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Director Higgins Michael J was granted 9,090 shares, increasing direct ownership by 42% to 30,740 units (SEC Form 4)

    4 - Cyclerion Therapeutics, Inc. (0001755237) (Issuer)

    3/27/25 4:20:44 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CYCN
    SEC Filings

    View All

    Amendment: SEC Form SCHEDULE 13G/A filed by Cyclerion Therapeutics Inc.

    SCHEDULE 13G/A - Cyclerion Therapeutics, Inc. (0001755237) (Subject)

    8/14/25 4:05:22 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 10-Q filed by Cyclerion Therapeutics Inc.

    10-Q - Cyclerion Therapeutics, Inc. (0001755237) (Filer)

    8/5/25 4:30:55 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 8-K filed by Cyclerion Therapeutics Inc.

    8-K - Cyclerion Therapeutics, Inc. (0001755237) (Filer)

    6/18/25 4:41:21 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CYCN
    Leadership Updates

    Live Leadership Updates

    View All

    Cyclerion Appoints Regina Graul, Ph.D., as President

    – Dr. Graul will lead the rebuild of Cyclerion, bringing more than two decades of drug making experience, R&D portfolio leadership, and a deep expertise in company strategy – – Peter Hecht, Ph.D., will continue to work closely with Cyclerion leadership as a strategic consultant and longstanding board member; steps down from CEO role – CAMBRIDGE, Mass., Dec. 04, 2023 (GLOBE NEWSWIRE) -- Cyclerion Therapeutics, Inc. (NASDAQ:CYCN), a biopharmaceutical company on a mission to develop treatments for serious diseases, today announced that Regina Graul, Ph.D., has joined the company as president, effective immediately. As Cyclerion's president, she will lead the organization and will work close

    12/4/23 8:00:00 AM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Cyclerion Announces CY6463 Clinical Pipeline Progress and Second Quarter 2022 Financial Results

    Positive topline results for CY6463 announced in two clinical studies in patients with Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like episodes (MELAS) and Cognitive Impairment Associated with Schizophrenia (CIAS) Study in Alzheimer's Disease with vascular pathology (ADv) enrollment ongoing Appointed Steven E. Hyman, M.D. to its Board of Directors CAMBRIDGE, Mass., Aug. 09, 2022 (GLOBE NEWSWIRE) -- Cyclerion Therapeutics, Inc. (NASDAQ:CYCN), a clinical-stage biopharmaceutical company on a mission to develop treatments that restore cognitive function, today announced second quarter 2022 financial results and a business update. "The data generated from our recent

    8/9/22 4:00:00 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Steven E. Hyman, M.D., Appointed to Cyclerion Therapeutics' Board of Directors

    CAMBRIDGE, Mass., July 26, 2022 (GLOBE NEWSWIRE) -- Cyclerion Therapeutics, Inc. (NASDAQ:CYCN), a clinical-stage biopharmaceutical company on a mission to develop treatments that restore cognitive function, today announced the appointment of Steven E. Hyman, M.D., to its Board of Directors effective July 25. Dr. Hyman will work with Cyclerion leadership to help shape the future of its research and clinical development strategy while expanding external collaborations with scientific leaders and industry partners. "We are delighted to welcome Dr. Steve Hyman to Cyclerion. Steve is a world-renowned leader in neuroscience with deep expertise leading large-scale, collaborative research program

    7/26/22 7:00:00 AM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $CYCN
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    Amendment: SEC Form SC 13G/A filed by Cyclerion Therapeutics Inc.

    SC 13G/A - Cyclerion Therapeutics, Inc. (0001755237) (Subject)

    7/12/24 6:17:25 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SC 13G/A filed by Cyclerion Therapeutics Inc. (Amendment)

    SC 13G/A - Cyclerion Therapeutics, Inc. (0001755237) (Subject)

    2/14/24 4:05:40 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SC 13G/A filed by Cyclerion Therapeutics Inc. (Amendment)

    SC 13G/A - Cyclerion Therapeutics, Inc. (0001755237) (Subject)

    2/9/24 5:06:49 PM ET
    $CYCN
    Biotechnology: Pharmaceutical Preparations
    Health Care