Immix Biopharma Reports NXC-201 Relapsed/Refractory AL Amyloidosis Clinical Data In ASGCT 2024 Oral Presentation
92% (12/13) overall response rate (ORR) for relapsed/refractory AL Amyloidosis patients enrolled in NEXICART-1:
- 12 out of 12 patients not exposed to prior BCMA-targeted bispecific responded to NXC-201 (100% ORR), of which 9 out of 12 were complete responders (75% CRs)
- 1 patient with prior exposure to BCMA-targeted bispecific treatment did not respond
- Best responder duration of response was 28.0 months with response ongoing as of May 10, 2024
- U.S. prevalence of relapsed/refractory AL Amyloidosis is growing 12% per year according to Staron, et al Blood Cancer Journal, estimated to reach 33,277 patients in 2024
- U.S. prevalence of relapsed/refractory AL Amyloidosis is growing 12% per year according to Staron, et al Blood Cancer Journal, estimated to reach 33,277 patients in 2024