• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Dashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlerts
    Company
    AboutQuantisnow PlusContactJobs
    Legal
    Terms of usePrivacy policyCookie policy

    Intra-Cellular Therapies Reports Fourth Quarter and Full-Year 2024 Financial Results

    2/21/25 8:00:48 AM ET
    $ITCI
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ITCI alert in real time by email

    Fourth quarter 2024 CAPLYTA net product sales grew to $199.2 million, representing a 51% increase over the same period in 2023

    Full year 2024 CAPLYTA net product sales were $680.5 million, representing year-over-year growth of 47%

    The U.S. Food and Drug Administration (FDA) accepted for review the lumateperone supplemental New Drug Application (sNDA) submission for adjunctive treatment of major depressive disorder (MDD)

    BEDMINSTER, N.J., Feb. 21, 2025 (GLOBE NEWSWIRE) -- Intra-Cellular Therapies, Inc. (NASDAQ:ITCI), a biopharmaceutical company focused on the development and commercialization of therapeutics for central nervous system (CNS) disorders, today announced its financial results for the fourth quarter ended December 31, 2024 and provided a corporate update.

    Financial Highlights

    • Net product sales of CAPLYTA were $680.5 million for the full year 2024. This represents an increase of 47% compared to 2023. Net product sales of CAPLYTA were $199.2 million for the fourth quarter of 2024, compared to $131.5 million for the same period in 2023, representing 51% growth.
    • Selling, general and administrative (SG&A) expenses were $504.5 million for the year ended December 31, 2024, compared to $409.9 million for the same period in 2023. This increase is primarily due to an increase in commercialization, marketing and infrastructure costs.
    • Research and development (R&D) expenses were $236.1 million for the year ended December 31, 2024, compared to $180.1 million for the same period in 2023. This increase is primarily due to higher lumateperone and non-lumateperone project costs, including the ITI-1284, ITI-214, and ITI-1500 programs.
    • Cash, cash equivalents, investment securities, and restricted cash totaled $1.0 billion on December 31, 2024, compared to $499.7 million at December 31, 2023.

    Commercial and Clinical Highlights

    • In the first quarter of 2025, we commenced a field sales force expansion in anticipation of the potential approval of CAPLYTA for the adjunctive treatment of MDD.
    • The FDA has accepted for review the sNDA for lumateperone, an investigational agent for the treatment of MDD as adjunctive therapy. Two positive Phase 3 global placebo-controlled studies, Study 501 and Study 502, as well as the long term open-label safety Study 503, form the basis of the sNDA.
    • Advancing our pipeline: In 2024, we initiated 10 late-stage clinical trials including six Phase 3 lumateperone clinical trials and four ITI-1284 clinical trials.



      Lumateperone: In our pediatric program, in the fourth quarter of 2024, we commenced patient enrollment in two Phase 3 studies in pediatric patients for the treatment of irritability associated with autism spectrum disorder. Patient enrollment is ongoing in our double-blind, placebo-controlled study in bipolar depression and in our open-label safety study in schizophrenia and bipolar disorder in pediatric patients.



      Patient enrollment is ongoing in our two Phase 3 studies evaluating lumateperone in adults in the acute treatment of manic or mixed episodes associated with bipolar I disorder (bipolar mania).
    • ITI-1284-ODT-SL program: Patient enrollment is ongoing in two Phase 2 clinical studies evaluating ITI-1284 in patients with generalized anxiety disorder (GAD). Our first study evaluates ITI-1284 as an adjunctive therapy to approved GAD medications while a second study evaluates ITI-1284 as monotherapy.



      Patient enrollment continues in a Phase 2 clinical study evaluating ITI-1284 in patients with psychosis associated with Alzheimer's disease (AD) and in our Phase 2 program in agitation associated with AD.
    • Other pipeline programs:



      Phosphodiesterase type I inhibitor (PDE1) program: Patient enrollment in our lenrispodun (ITI-214) Phase 2 Study in Parkinson's disease (PD) is ongoing. Our second PDE1 inhibitor, ITI-1020 being developed in oncology indications, continues its Phase 1 single ascending dose study in healthy volunteers.



      ITI-1500 non-hallucinogenic neuroplastogen program: ITI-1549 is advancing IND enabling studies.

    Important Safety Information

    Boxed Warnings:

    • Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. CAPLYTA is not approved for the treatment of patients with dementia-related psychosis.
    • Antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adults in short-term studies. All antidepressant-treated patients should be closely monitored for clinical worsening, and for emergence of suicidal thoughts and behaviors. The safety and effectiveness of CAPLYTA have not been established in pediatric patients.

    Contraindications: CAPLYTA is contraindicated in patients with known hypersensitivity to lumateperone or any components of CAPLYTA. Reactions have included pruritus, rash (e.g., allergic dermatitis, papular rash, and generalized rash), and urticaria.

    Warnings & Precautions: Antipsychotic drugs have been reported to cause:

    • Cerebrovascular Adverse Reactions in Elderly Patients with Dementia-Related Psychosis, including stroke and transient ischemic attack. See Boxed Warning above.
    • Neuroleptic Malignant Syndrome (NMS), which is a potentially fatal reaction. Signs and symptoms include: high fever, stiff muscles, confusion, changes in breathing, heart rate, and blood pressure, elevated creatinine phosphokinase, myoglobinuria (and/or rhabdomyolysis), and acute renal failure. Patients who experience signs and symptoms of NMS should immediately contact their doctor or go to the emergency room.
    • Tardive Dyskinesia, a syndrome of uncontrolled body movements in the face, tongue, or other body parts, which may increase with duration of treatment and total cumulative dose. TD may not go away, even if CAPLYTA is discontinued. It can also occur after CAPLYTA is discontinued.
    • Metabolic Changes, including hyperglycemia, diabetes mellitus, dyslipidemia, and weight gain. Hyperglycemia, in some cases extreme and associated with ketoacidosis, hyperosmolar coma or death, has been reported in patients treated with antipsychotics. Measure weight and assess fasting plasma glucose and lipids when initiating CAPLYTA and monitor periodically during long-term treatment.
    • Leukopenia, Neutropenia, and Agranulocytosis (including fatal cases). Complete blood counts should be performed in patients with pre-existing low white blood cell count (WBC) or history of leukopenia or neutropenia. CAPLYTA should be discontinued if clinically significant decline in WBC occurs in absence of other causative factors.
    • Decreased Blood Pressure & Dizziness. Patients may feel lightheaded, dizzy or faint when they rise too quickly from a sitting or lying position (orthostatic hypotension). Heart rate and blood pressure should be monitored and patients should be warned with known cardiovascular or cerebrovascular disease. Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension.
    • Falls. CAPLYTA may cause sleepiness or dizziness and can slow thinking and motor skills, which may lead to falls and, consequently, fractures and other injuries. Patients should be assessed for risk when using CAPLYTA.
    • Seizures. CAPLYTA should be used cautiously in patients with a history of seizures or with conditions that lower seizure threshold.
    • Potential for Cognitive and Motor Impairment. Patients should use caution when operating machinery or motor vehicles until they know how CAPLYTA affects them.
    • Body Temperature Dysregulation. CAPLYTA should be used with caution in patients who may experience conditions that may increase core body temperature such as strenuous exercise, extreme heat, dehydration, or concomitant anticholinergics.
    • Dysphagia. CAPLYTA should be used with caution in patients at risk for aspiration.

    Drug Interactions: CAPLYTA should not be used with CYP3A4 inducers. Dose reduction is recommended for concomitant use with strong CYP3A4 inhibitors or moderate CYP3A4 inhibitors.

    Special Populations: Newborn infants exposed to antipsychotic drugs during the third trimester of pregnancy are at risk for extrapyramidal and/or withdrawal symptoms following delivery. Dose reduction is recommended for patients with moderate or severe hepatic impairment.

    Adverse Reactions: The most common adverse reactions in clinical trials with CAPLYTA vs. placebo were somnolence/sedation, dizziness, nausea, and dry mouth.

    CAPLYTA is available in 10.5 mg, 21 mg, and 42 mg capsules.

    Please click here to see full Prescribing Information including Boxed Warning.

    About CAPLYTA (lumateperone)

    CAPLYTA 42 mg is an oral, once daily atypical antipsychotic approved in adults for the treatment of schizophrenia and the treatment of depressive episodes associated with bipolar I or II disorder (bipolar depression) as monotherapy and as adjunctive therapy with lithium or valproate. While the mechanism of action of CAPLYTA is unknown, the efficacy of CAPLYTA could be mediated through a combination of antagonist activity at central serotonin 5-HT2A receptors and postsynaptic antagonist activity at central dopamine D2 receptors.

    Lumateperone is being studied for the treatment of major depressive disorder, and other psychiatric and neurological disorders. Lumateperone is not FDA-approved for these disorders.

    About Intra-Cellular Therapies

    Intra-Cellular Therapies is a biopharmaceutical company founded on Nobel prize-winning research that allows us to understand how therapies affect the inner-workings of cells in the body. The company leverages this intracellular approach to develop innovative treatments for people living with complex psychiatric and neurologic diseases. For more information, please visit www.intracellulartherapies.com.

    Forward-Looking Statements

    This news release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995 that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include statements regarding, among other things, the potential approval of CAPLYTA (lumateperone) for the treatment of major depressive disorder as adjunctive therapy; our financial and operating performance, including our future revenues and expenses; our expectations regarding the commercialization of CAPLYTA; our plans to expand our sales force; our plans to conduct clinical or non-clinical trials and the timing of developments with respect to those trials, including enrollment, initiation or completion of clinical conduct, or the availability or reporting of results; whether clinical trial results will be predictive of future real-world results; whether CAPLYTA will serve an unmet need; the goals of our development programs; our beliefs about the potential utility of our product candidates; and development efforts and plans under the caption "About Intra-Cellular Therapies." All such forward-looking statements are based on management's present expectations and are subject to certain factors, risks and uncertainties that may cause actual results, outcome of events, timing and performance to differ materially from those expressed or implied by such statements. These risks and uncertainties include, but are not limited to, the following: there is no guarantee we will complete the pending transaction with Johnson & Johnson within the timeframe we anticipate or at all; there are no guarantees that CAPLYTA will be commercially successful; we may encounter issues, delays or other challenges in commercializing CAPLYTA; whether CAPLYTA receives adequate reimbursement from third-party payors; the degree to which CAPLYTA receives acceptance from patients and physicians for its approved indications; challenges associated with execution of our sales activities, which in each case could limit the potential of our product; results achieved in CAPLYTA in the treatment of schizophrenia and bipolar depression following commercial launch of the product may be different than observed in clinical trials, and may vary among patients; challenges associated with supply and manufacturing activities, which in each case could limit our sales and the availability of our product; risks associated with our current and planned clinical trials; we may encounter unexpected safety or tolerability issues with CAPLYTA following commercial launch for the treatment of schizophrenia or bipolar depression or in ongoing or future trials and other development activities; there is no guarantee that a generic equivalent of CAPLYTA will not be approved and enter the market before the expiration of our patents; there is no guarantee that our sNDA for the adjunctive treatment of MDD will be approved, if at all, on the timeline that we expect; our other product candidates may not be successful or may take longer and be more costly than anticipated; product candidates that appeared promising in earlier research and clinical trials may not demonstrate safety and/or efficacy in larger-scale or later clinical trials or in clinical trials for other indications; our proposals with respect to the regulatory path for our product candidates may not be acceptable to the FDA; our reliance on collaborative partners and other third parties for development of our product candidates; impacts on our business, including on the commercialization of CAPLYTA and our clinical trials, as a result of the COVID-19 pandemic, the conflicts in Ukraine, Russia and the Middle East, global economic uncertainty, inflation, higher interest rates or market disruptions; and the other risk factors detailed in our public filings with the Securities and Exchange Commission. All statements contained in this press release are made only as of the date of this press release, and we do not intend to update this information unless required by law.

    Contact:

    Intra-Cellular Therapies, Inc.

    Juan Sanchez, M.D.

    Vice President, Corporate Communications and Investor Relations

    646-440-9333

    Burns McClellan, Inc.

    Cameron Radinovic

    [email protected]

    212-213-0006

    INTRA-CELLULAR THERAPIES, INC.

    CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

    (in thousands except share and per share amounts) (Unaudited) (1)(2)
     
     Three Months Ended December 31,  Twelve Months Ended December 31,
      2024   2023   2024   2023 
    Revenues       
    Product sales, net$199,223  $131,507  $680,501  $462,175 
    Grant revenue —   593   351   2,195 
    Total revenues, net 199,223   132,100   680,852   464,370 
    Operating expenses:       
    Cost of product sales 20,405   10,703   56,963   33,745 
    Selling, general and administrative 137,729   104,720   504,489   409,864 
    Research and development 70,286   50,773   236,121   180,142 
    Total operating expenses 228,420   166,196   797,573   623,751 
    Loss from operations (29,197)  (34,096)  (116,721)  (159,381)
    Interest income 11,995   6,242   42,518   20,343 
    Loss before provision for income taxes (17,202)  (27,854)  (74,203)  (139,038)
    Income tax expense 317   (450)  (473)  (636)
    Net loss$(16,885) $(28,304) $(74,676) $(139,674)
    Net loss per common share:       
    Basic & Diluted$(0.16) $(0.29) $(0.72) $(1.46)
    Weighted average number of common shares:       
    Basic & Diluted 106,095,836   96,285,558   103,131,017   95,881,729 
                    

    (1) The condensed consolidated statements of operations for the three and twelve months ended December 31, 2024 and 2023 have been derived from the financial statements but do not include all of the information and footnotes required by accounting principles generally accepted in the United States for complete financial statements.

    (2) Some amounts in this statement may not add due to rounding. All percentages have been calculated using unrounded amounts.

    INTRA-CELLULAR THERAPIES, INC.



    CONDENSED CONSOLIDATED BALANCE SHEETS

    (in thousands except share and per share amounts) (Unaudited)
     
     December 31,

    2024
     December 31,

    2023
    Assets   
    Current assets:   
    Cash and cash equivalents$306,948  $147,767 
    Investment securities, available-for-sale 694,118   350,174 
    Restricted cash 1,750   1,750 
    Accounts receivable, net 166,500   114,018 
    Inventory 26,283   11,647 
    Prepaid expenses and other current assets 111,765   42,443 
    Total current assets 1,307,364   667,799 
    Property and equipment, net 1,468   1,654 
    Right of use assets, net 13,428   12,928 
    Inventory, non-current 38,890   38,621 
    Other assets 5,762   7,293 
    Total assets$1,366,912  $728,295 
    Liabilities and stockholders' equity   
    Current liabilities:   
    Accounts payable$26,074  $11,452 
    Accrued and other current liabilities 65,215   27,944 
    Accrued customer programs 75,408   53,173 
    Accrued employee benefits 34,774   27,364 
    Operating lease liabilities 4,233   3,612 
    Total current liabilities 205,704   123,545 
    Operating lease liabilities, non-current 12,748   13,326 
    Total liabilities 218,452   136,871 
    Stockholders' equity:   
    Common stock, $0.0001 par value: 175,000,000 shares authorized at December 31, 2024 and December 31, 2023, respectively; 106,240,009 and 96,379,811 shares issued and outstanding at December 31, 2024 and December 31, 2023, respectively 11   10 
    Additional paid-in capital 2,840,094   2,208,470 
    Accumulated deficit (1,691,836)  (1,617,160)
    Accumulated comprehensive income 191   104 
    Total stockholders' equity 1,148,460   591,424 
    Total liabilities and stockholders' equity$1,366,912  $728,295 
            

    The condensed consolidated balance sheets at December 31, 2024 and December 31, 2023 have been derived from the financial statements but do not include all of the information and footnotes required by accounting principles generally accepted in the United States for complete financial statements.



    Primary Logo

    Get the next $ITCI alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $ITCI

    DatePrice TargetRatingAnalyst
    2/24/2025$140.00 → $132.00Outperform → Neutral
    Mizuho
    1/31/2025$119.00 → $132.00Buy → Hold
    Canaccord Genuity
    9/6/2024$68.00 → $92.00Neutral → Overweight
    Piper Sandler
    1/3/2024$83.00Outperform
    Robert W. Baird
    12/11/2023$75.00Outperform
    TD Cowen
    4/20/2023$80.00Overweight
    Morgan Stanley
    8/22/2022$64.00 → $49.00Buy → Neutral
    Goldman
    7/7/2022$74.00Buy
    Mizuho
    More analyst ratings

    $ITCI
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Intra-Cellular Therapies downgraded by Mizuho with a new price target

      Mizuho downgraded Intra-Cellular Therapies from Outperform to Neutral and set a new price target of $132.00 from $140.00 previously

      2/24/25 7:10:56 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Intra-Cellular Therapies downgraded by Canaccord Genuity with a new price target

      Canaccord Genuity downgraded Intra-Cellular Therapies from Buy to Hold and set a new price target of $132.00 from $119.00 previously

      1/31/25 7:02:57 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Intra-Cellular Therapies upgraded by Piper Sandler with a new price target

      Piper Sandler upgraded Intra-Cellular Therapies from Neutral to Overweight and set a new price target of $92.00 from $68.00 previously

      9/6/24 7:44:31 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ITCI
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Phathom Pharmaceuticals Reports First Quarter 2025 Financial Results and Provides Business Update

      VOQUEZNA launch momentum continues with over 390,000 prescriptions filled to date, written by more than 23,600 healthcare providersNet revenues of $28.5 million reported for Q1Filled VOQUEZNA prescriptions increased ~8% in Q1 over the prior quarter despite seasonal headwindsStrategic cost reductions and executive leadership changes implemented to support sustainable revenue growth and achieve profit from operations, excluding stock-based compensation, in 2026Management to host conference call today, May 1, 2025, at 8:00 a.m. ET FLORHAM PARK, N.J., May 01, 2025 (GLOBE NEWSWIRE) -- Phathom Pharmaceuticals, Inc. (NASDAQ:PHAT), a biopharmaceutical company focused on developing and commerciali

      5/1/25 7:00:41 AM ET
      $ITCI
      $PHAT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Intra-Cellular Therapies Reports Fourth Quarter and Full-Year 2024 Financial Results

      Fourth quarter 2024 CAPLYTA net product sales grew to $199.2 million, representing a 51% increase over the same period in 2023 Full year 2024 CAPLYTA net product sales were $680.5 million, representing year-over-year growth of 47% The U.S. Food and Drug Administration (FDA) accepted for review the lumateperone supplemental New Drug Application (sNDA) submission for adjunctive treatment of major depressive disorder (MDD) BEDMINSTER, N.J., Feb. 21, 2025 (GLOBE NEWSWIRE) -- Intra-Cellular Therapies, Inc. (NASDAQ:ITCI), a biopharmaceutical company focused on the development and commercialization of therapeutics for central nervous system (CNS) disorders, today announced its financial result

      2/21/25 8:00:48 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Johnson & Johnson Strengthens Neuroscience Leadership with Acquisition of Intra-Cellular Therapies, Inc.

      Acquisition includes CAPLYTA® (lumateperone), the first and only U.S. FDA-approved treatment for bipolar I and II depression as an adjunctive and monotherapy; also approved for the treatment of schizophrenia in adults sNDA submitted to U.S. FDA for CAPLYTA® as adjunctive treatment for major depressive disorder; if approved, CAPLYTA® has potential to become a standard of care for most common depressive disorders CAPLYTA® adds to Johnson & Johnson's robust lineup of therapies with $5 billion+ potential in peak year salesi and further solidifies sales growth above analyst expectations now through the remainder of the decade Promising clinical-stage pipeline with best-in-disease potent

      1/13/25 6:32:27 AM ET
      $ITCI
      $JNJ
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ITCI
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Director Salas Eduardo Rene returned $206,844 worth of shares to the company (1,567 units at $132.00), closing all direct ownership in the company (SEC Form 4)

      4 - Intra-Cellular Therapies, Inc. (0001567514) (Issuer)

      4/2/25 8:34:41 PM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Riggs Rory B returned $17,359,584 worth of shares to the company (131,512 units at $132.00), closing all direct ownership in the company (SEC Form 4)

      4 - Intra-Cellular Therapies, Inc. (0001567514) (Issuer)

      4/2/25 5:47:21 PM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • President Halstead Michael returned $2,812,524 worth of shares to the company (21,307 units at $132.00), closing all direct ownership in the company (SEC Form 4)

      4 - Intra-Cellular Therapies, Inc. (0001567514) (Issuer)

      4/2/25 5:46:14 PM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ITCI
    SEC Filings

    See more
    • SEC Form 15-12G filed by Intra-Cellular Therapies Inc.

      15-12G - Intra-Cellular Therapies, Inc. (0001567514) (Filer)

      4/14/25 8:55:29 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form EFFECT filed by Intra-Cellular Therapies Inc.

      EFFECT - Intra-Cellular Therapies, Inc. (0001567514) (Filer)

      4/10/25 12:15:05 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form POSASR filed by Intra-Cellular Therapies Inc.

      POSASR - Intra-Cellular Therapies, Inc. (0001567514) (Filer)

      4/2/25 4:32:55 PM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ITCI
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • Amendment: SEC Form SC 13G/A filed by Intra-Cellular Therapies Inc.

      SC 13G/A - Intra-Cellular Therapies, Inc. (0001567514) (Subject)

      11/12/24 10:32:13 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G filed by Intra-Cellular Therapies Inc.

      SC 13G - Intra-Cellular Therapies, Inc. (0001567514) (Subject)

      10/10/24 12:36:28 PM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Intra-Cellular Therapies Inc. (Amendment)

      SC 13G/A - Intra-Cellular Therapies, Inc. (0001567514) (Subject)

      2/13/24 5:08:02 PM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ITCI
    Financials

    Live finance-specific insights

    See more
    • Phathom Pharmaceuticals Reports First Quarter 2025 Financial Results and Provides Business Update

      VOQUEZNA launch momentum continues with over 390,000 prescriptions filled to date, written by more than 23,600 healthcare providersNet revenues of $28.5 million reported for Q1Filled VOQUEZNA prescriptions increased ~8% in Q1 over the prior quarter despite seasonal headwindsStrategic cost reductions and executive leadership changes implemented to support sustainable revenue growth and achieve profit from operations, excluding stock-based compensation, in 2026Management to host conference call today, May 1, 2025, at 8:00 a.m. ET FLORHAM PARK, N.J., May 01, 2025 (GLOBE NEWSWIRE) -- Phathom Pharmaceuticals, Inc. (NASDAQ:PHAT), a biopharmaceutical company focused on developing and commerciali

      5/1/25 7:00:41 AM ET
      $ITCI
      $PHAT
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Intra-Cellular Therapies Reports Fourth Quarter and Full-Year 2024 Financial Results

      Fourth quarter 2024 CAPLYTA net product sales grew to $199.2 million, representing a 51% increase over the same period in 2023 Full year 2024 CAPLYTA net product sales were $680.5 million, representing year-over-year growth of 47% The U.S. Food and Drug Administration (FDA) accepted for review the lumateperone supplemental New Drug Application (sNDA) submission for adjunctive treatment of major depressive disorder (MDD) BEDMINSTER, N.J., Feb. 21, 2025 (GLOBE NEWSWIRE) -- Intra-Cellular Therapies, Inc. (NASDAQ:ITCI), a biopharmaceutical company focused on the development and commercialization of therapeutics for central nervous system (CNS) disorders, today announced its financial result

      2/21/25 8:00:48 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Johnson & Johnson Strengthens Neuroscience Leadership with Acquisition of Intra-Cellular Therapies, Inc.

      Acquisition includes CAPLYTA® (lumateperone), the first and only U.S. FDA-approved treatment for bipolar I and II depression as an adjunctive and monotherapy; also approved for the treatment of schizophrenia in adults sNDA submitted to U.S. FDA for CAPLYTA® as adjunctive treatment for major depressive disorder; if approved, CAPLYTA® has potential to become a standard of care for most common depressive disorders CAPLYTA® adds to Johnson & Johnson's robust lineup of therapies with $5 billion+ potential in peak year salesi and further solidifies sales growth above analyst expectations now through the remainder of the decade Promising clinical-stage pipeline with best-in-disease potent

      1/13/25 6:32:27 AM ET
      $ITCI
      $JNJ
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ITCI
    Leadership Updates

    Live Leadership Updates

    See more
    • Intra-Cellular Therapies Announces Appointment of Sanjeev Narula as Chief Financial Officer

      NEW YORK, Aug. 07, 2024 (GLOBE NEWSWIRE) -- Intra-Cellular Therapies, Inc. (NASDAQ:ITCI), a biopharmaceutical company focused on the development and commercialization of therapeutics for central nervous system (CNS) disorders, today announced that Sanjeev Narula will join the Company on August 12, 2024 and will serve as Executive Vice President, Chief Financial Officer. Mr. Narula will report to Dr. Sharon Mates, ITCI's Chairman and Chief Executive Officer. Lawrence Hineline, who currently serves as Chief Financial Officer, will retire on the same date but will continue to serve as a consultant to the Company for a period of time to ensure a smooth transition. "I am excited to welcome Mr.

      8/7/24 7:40:54 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Intra-Cellular Therapies Announces Appointment of E. Rene Salas to Board of Directors

      NEW YORK, April 21, 2022 (GLOBE NEWSWIRE) -- Intra-Cellular Therapies, Inc. (NASDAQ:ITCI), a biopharmaceutical company focused on the development and commercialization of therapeutics for central nervous system (CNS) disorders, today announced the appointment of E. Rene Salas to the Intra-Cellular Therapies Board of Directors. Mr. Salas will serve as a member of the audit committee. "We are pleased to welcome Rene Salas to the Intra-Cellular Therapies Board," said Dr. Sharon Mates, Chairman and CEO of Intra-Cellular Therapies. "Rene's extensive financial and life sciences advisory experience will be very valuable as we continue to grow our business and pursue our mission to develop innova

      4/21/22 8:00:00 AM ET
      $ITCI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Cibus Appoints Co-Founder Rory Riggs, as Chief Executive Officer

      Cibus, a leading agricultural biotechnology company, announced today the appointment of Rory Riggs, co-founder, and Chairman of Cibus, to serve as Chief Executive Officer. He will succeed Peter Beetham, PhD, also a Cibus co-founder, who has been appointed President and Chief Operating Officer of the 20-year-old company. "Since our founding, Rory has been an important strategic partner in the success of Cibus and we are pleased that he is deepening his involvement in the company's growth as CEO," said Dr. Beetham. "With the recent progress toward a European approval of Cibus' proprietary precision gene-editing technology, as well as other recent Cibus commercial announcements, this manageme

      10/7/21 9:00:00 AM ET
      $FGEN
      $ITCI
      $RPRX
      Biotechnology: Pharmaceutical Preparations
      Health Care