Iovance Biotherapeutics, Nio, NetEase And Other Big Stocks Moving Lower On Wednesday

U.S. stocks traded mixed, with the Dow Jones index gaining around 70 points on Wednesday.

Shares of Iovance Biotherapeutics, Inc. (NASDAQ:IOVA) fell sharply during Wednesday’s session after the company announced a clinical program update for LN-145 TIL therapy in non-small lung cancer (NSCLC).

The FDA placed a clinical hold on the IOV-LUN-202 trial on December 22, 2023, in response to a recently reported Grade 5 (fatal) serious adverse event potentially related to the non-myeloablative lymphodepletion pre-conditioning regimen.
Iovance Biotherapeutics shares dipped 20.4% to $7.07 on Wednesday.

Here are some other big stocks recording gains in today’s session.

• Nukkleus Inc. (NASDAQ:NUKK) shares declined 28.8% to $2.60 after jumping around 11% on Tuesday.
• GreenTree Hospitality Group Ltd. (NYSE:GHG) fell 10% to $3.69.
• InnSuites Hospitality Trust (NYSE:IHT) dipped 8.6% to $1.4250.
• LanzaTech Global, Inc. (NASDAQ:LNZA) fell 7.6% to $5.00.
• Life Time Group Holdings, Inc. (NYSE:LTH) fell 6.9% to $14.30. On Dec 22, Life Time Group Holdings agreed with company’s CFO, Robert Houghton that he will resign as CFO.
• Cheche Group Inc. (NASDAQ:CCG) fell 6.3% to $6.51.
• Canopy Growth Corporation (NASDAQ:CGC) declined 6.2% to $5.31.
• Velocity Financial, Inc. (NYSE:VEL) fell 4.8% to $15.62.
• The Beauty Health Company (NASDAQ:SKIN) fell 4.8% to $3.0850.
• NetEase, Inc. (NASDAQ:NTES) fell 4.2% to $88.30 on continued volatility amid regulatory developments in China's gaming sector.
• NIO Inc. (NYSE:NIO) fell 4.1% to $8.95 after rising more than 10% on Tuesday. Nio stock raced higher to start the week after the company launched its new ET9 sedan at its Nio Day event over the weekend.

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