• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
PublishGo to App
    Quantisnow Logo

    © 2026 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEWLLM Arena
    Legal
    Terms of usePrivacy policyCookie policy

    Maze Therapeutics Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

    8/12/25 4:06:06 PM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $MAZE alert in real time by email
    8-K
    false000184229500018422952025-08-122025-08-12

     

    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    WASHINGTON, D.C. 20549

     

    FORM 8-K

     

    CURRENT REPORT

    Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

    Date of Report (Date of earliest event reported): August 12, 2025

     

     

    Maze Therapeutics, Inc.

    (Exact name of Registrant as Specified in Its Charter)

     

     

    Delaware

    001-42490

    82-2635018

    (State or Other Jurisdiction
    of Incorporation)

    (Commission File Number)

    (IRS Employer
    Identification No.)

     

     

     

     

     

    171 Oyster Point Blvd., Suite 300

     

    South San Francisco, California

     

    94080

    (Address of Principal Executive Offices)

     

    (Zip Code)

     

    Registrant’s Telephone Number, Including Area Code: 650 850-5070

     

     

    (Former Name or Former Address, if Changed Since Last Report)

     

    Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

    ☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
    ☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
    ☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
    ☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

    Securities registered pursuant to Section 12(b) of the Act:


    Title of each class

     

    Trading
    Symbol(s)

     


    Name of each exchange on which registered

    Common Stock - par value $0.001 per share

     

    MAZE

     

    The Nasdaq Stock Market LLC

    Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

    Emerging growth company ☒

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

     


    Item 2.02 Results of Operations and Financial Condition.

    On August 12, 2025, Maze Therapeutics Inc. (the “Company”) issued a press release reporting its financial results for the second quarter ended June 30, 2025. The full text of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K.

    The information in Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that Section or Section 11 or 12(a)(2) of the Securities Act of 1933, as amended (the “Securities Act”), nor shall it be deemed incorporated by reference into any filing by the Company under the Exchange Act or the Securities Act, whether made before or after the date hereof, except as expressly set forth by reference in such filing.

    Item 9.01 Financial Statements and Exhibits.

     

    Exhibit

    Number

    Description

    99.1*

    Press Release dated August 12, 2025.

    104

     

    Cover Page Interactive Data File (embedded within the Inline XBRL document)

    * Filed herewith.


     

    SIGNATURES

    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

     

     

     

     

     

     

     

     

    Date:

    August 12, 2025

    By:

    /s/ Courtney Phillips

     

     

     

    Courtney Phillips

    General Counsel and Corporate Secretary

     


    Get the next $MAZE alert in real time by email

    Crush Q1 2026 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $MAZE

    DatePrice TargetRatingAnalyst
    12/4/2025$55.00Overweight
    Wells Fargo
    11/14/2025Outperform
    Raymond James
    9/2/2025$30.00Buy
    BTIG Research
    7/23/2025$34.00Buy
    H.C. Wainwright
    7/8/2025$17.00Outperform
    Wedbush
    More analyst ratings

    $MAZE
    SEC Filings

    View All

    Amendment: SEC Form SCHEDULE 13G/A filed by Maze Therapeutics Inc.

    SCHEDULE 13G/A - Maze Therapeutics, Inc. (0001842295) (Subject)

    2/13/26 5:25:23 PM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form S-8 filed by Maze Therapeutics Inc.

    S-8 - Maze Therapeutics, Inc. (0001842295) (Filer)

    2/4/26 5:20:47 PM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form S-3ASR filed by Maze Therapeutics Inc.

    S-3ASR - Maze Therapeutics, Inc. (0001842295) (Filer)

    2/4/26 5:17:42 PM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $MAZE
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Wells Fargo initiated coverage on Maze Therapeutics with a new price target

    Wells Fargo initiated coverage of Maze Therapeutics with a rating of Overweight and set a new price target of $55.00

    12/4/25 8:45:11 AM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Raymond James initiated coverage on Maze Therapeutics

    Raymond James initiated coverage of Maze Therapeutics with a rating of Outperform

    11/14/25 10:01:27 AM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    BTIG Research initiated coverage on Maze Therapeutics with a new price target

    BTIG Research initiated coverage of Maze Therapeutics with a rating of Buy and set a new price target of $30.00

    9/2/25 8:38:37 AM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $MAZE
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    SEC Form 4 filed by GC and Corp. Secretary Courtney Phillips

    4 - Maze Therapeutics, Inc. (0001842295) (Issuer)

    3/3/26 4:28:41 PM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    SEC Form 4 filed by Chief Executive Officer Coloma Jason V

    4 - Maze Therapeutics, Inc. (0001842295) (Issuer)

    3/3/26 4:17:17 PM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    President, R&D & CMO Bernstein Harold exercised 15,000 shares at a strike of $10.42 and sold $690,334 worth of shares (15,000 units at $46.02) (SEC Form 4)

    4 - Maze Therapeutics, Inc. (0001842295) (Issuer)

    2/4/26 4:25:47 PM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $MAZE
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    Chronic Kidney Disease Market Poised to Expand Significantly During Forecast Period (2025-2034) as Demand for Early Diagnosis and Novel Therapies Increases | DelveInsight

    The chronic kidney disease market growth is being driven by the rising global prevalence of diabetes, hypertension, and aging populations. Increasing awareness and earlier diagnosis are expanding the pool of patients eligible for treatment. Additionally, the launch of emerging therapies such as Zibotentan/Dapagliflozin and Baxdrostat/dapagliflozin (AstraZeneca), Vicadrostat + Empagliflozin (Boehringer Ingelheim), Lorundrostat (Mineralys Therapeutics), Rilparencel (ProKidney), DISC-0974 (Disc Medicine), Vonsetamig (Regeneron Pharmaceuticals), and others will further boost the market growth.LAS VEGAS, March 3, 2026 /PRNewswire/ -- Recently published Chronic Kidney Disease Market Insights repor

    3/3/26 5:31:00 PM ET
    $AMGN
    $IRON
    $JNJ
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Biotechnology: Pharmaceutical Preparations

    Maze Therapeutics to Participate in the TD Cowen 46th Annual Health Care Conference

    SOUTH SAN FRANCISCO, Calif., Feb. 25, 2026 (GLOBE NEWSWIRE) -- Maze Therapeutics, Inc. (NASDAQ:MAZE), a clinical-stage biopharmaceutical company developing small molecule precision medicines for patients with kidney and metabolic diseases, today announced that Jason Coloma, Ph.D., chief executive officer of Maze Therapeutics, will present at the TD Cowen 46th Annual Health Care Conference on Wednesday, March 4, 2026 at 10:30 a.m. ET. A live webcast of the event will be available in the Investors section of the Maze Therapeutics website at www.mazetx.com and archived for 60 days following the presentation. About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical co

    2/25/26 7:00:00 AM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Maze Therapeutics to Participate in the Guggenheim Emerging Outlook: Biotech Summit 2026

    SOUTH SAN FRANCISCO, Calif., Feb. 04, 2026 (GLOBE NEWSWIRE) -- Maze Therapeutics, Inc. (NASDAQ:MAZE), a clinical-stage biopharmaceutical company developing small molecule precision medicines for patients with kidney and metabolic diseases, today announced that Jason Coloma, Ph.D., chief executive officer of Maze Therapeutics, will present at the Guggenheim Emerging Outlook: Biotech Summit 2026 on Wednesday, February 11, 2026 at 3:00 p.m. ET. A live webcast of the event will be available in the Investors section of the Maze Therapeutics website at www.mazetx.com and archived for 60 days following the presentation. About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceu

    2/4/26 7:00:00 AM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $MAZE
    Leadership Updates

    Live Leadership Updates

    View All

    Maze Therapeutics Reports Third Quarter 2025 Financial Results and Recent Highlights

    First-in-human data from Phase 1 trial of MZE782 support best- and first-in-class potential; two Phase 2 proof-of-concept trials in phenylketonuria (PKU) and chronic kidney disease (CKD) expected to initiate in 2026 Enrollment ongoing in Phase 2 HORIZON trial of MZE829 in broad APOL1-mediated kidney disease (AMKD); topline data for initial patients expected by the end of Q1 2026 Strong balance sheet with $383.9 million in cash, cash equivalents and marketable securities following oversubscribed private placement; cash runway into 2028 SOUTH SAN FRANCISCO, Calif., Nov. 06, 2025 (GLOBE NEWSWIRE) -- Maze Therapeutics, Inc. (NASDAQ:MAZE), a clinical-stage biopharmaceutical company developin

    11/6/25 4:01:00 PM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    Maze Therapeutics Appoints Industry Veteran Hervé Hoppenot as Chairman of the Board of Directors

    SOUTH SAN FRANCISCO, Calif., Oct. 06, 2025 (GLOBE NEWSWIRE) -- Maze Therapeutics, Inc. (NASDAQ:MAZE), a clinical-stage biopharmaceutical company developing small molecule precision medicines for patients with kidney and metabolic diseases, today announced the appointment of Hervé Hoppenot as Chairman of its Board of Directors, succeeding Charles Homcy, M.D., who will continue to serve on the Board. "I am honored to assume the role of Chairman of the Board at this pivotal moment for Maze Therapeutics," said Mr. Hoppenot. "With encouraging first-in-human data for MZE782, an oversubscribed $150 million private placement, and important clinical milestones ahead, including the advancement of M

    10/6/25 7:00:50 AM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care

    $MAZE
    Financials

    Live finance-specific insights

    View All

    Maze Therapeutics Announces Positive First-in-Human Results from Phase 1 Trial of MZE782, Establishing Proof of Mechanism for a Potent, Oral SLC6A19 Inhibitor with Potential to Treat Phenylketonuria (PKU) and Chronic Kidney Disease (CKD)

    Phase 1 data in healthy volunteers exceed expectations and support best-in-class potential, enabling Phase 2 advancement for both intended indications of PKU and CKD Dose-dependent urinary amino acid excretion demonstrated across all SAD and MAD cohorts, including up to a 42-fold increase in urinary phenylalanine (Phe) excretion, a well-validated biomarker for PKU and predictive for CKD Dose-dependent initial eGFR dip similar to SGLT2 inhibitors observed, supporting a potential kidney protective effect in CKD Well tolerated across all doses with an excellent safety profile and no serious adverse events observed Phase 2 trials in both PKU and CKD expected to initiate in 2026 Maze to hos

    9/11/25 7:30:00 AM ET
    $MAZE
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care