NexImmune Announces Workforce Reduction to Enable Continued AIMTM Nanoparticle Platform Development Strategy

$NEXI
Biotechnology: Pharmaceutical Preparations
Health Care
Get the next $NEXI alert in real time by email
  • Company retains core capabilities to continue to advance its nanoparticle injection (AIM INJ) platform and potential product candidates in oncology and autoimmune diseases

GAITHERSBURG, Md., Aug. 31, 2023 (GLOBE NEWSWIRE) -- NexImmune, Inc. a biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted immune response by directing the function of antigen-specific T cells in oncology, autoimmune and infectious diseases, today announced that, in order to reduce its cash expenditures while continuing to pursue its existing strategic plan, its Board of Directors approved and its management is implementing an approximately 53% reduction in workforce, designed to reduce costs and extend the Company's cash. The realignment will reduce the Company's workforce from 47 to 22 full-time employees as of September 5, 2023.

"We continue to make significant progress in generating important, validating pre-clinical data for our off-the-shelf multi-antigen-specific T cell-directing products," said Kristi Jones, NexImmune's CEO. "The workforce reduction protects our core capabilities to advance novel therapeutic candidates and our multiplex validation of functional antigen-specific T cell responses while giving us additional flexibility to manage our business."

Jones continued: "The ability of our nanoparticles to direct T cell function has been validated in preclinical studies, not only by NexImmune, but also by our collaborators at leading institutions and other outside experts.   This validation underscores the significance of our technology and its potential to unlock new possibilities in the field of immuno-oncology and other disease areas."

"I want to express my sincere gratitude for the incredible work and dedication of our departing employees, whose contributions have been invaluable, and to the entire team for their dedication to our mission to deliver meaningful benefit to patients."

In connection with the workforce reduction, John Trainer, the Company's Chief Financial Officer, will depart the Company effective as of September 2, 2023. Mr. Trainer will transition to providing consulting and advisory services to the Company pursuant to a consulting agreement.

About NexImmune

NexImmune is developing novel approach to immunotherapy designed to employ the body's own T cells to generate a specific, potent, and durable immune response. The backbone of NexImmune's approach is a proprietary Artificial Immune Modulation (AIM™) nanoparticle technology platform. The AIM technology enables NexImmune to construct nanoparticles that function as synthetic dendritic cells capable of directing a specific T cell-mediated immune response. AIM constructed nanoparticles employ natural biology to engage, activate and expand endogenous T cells in ways that combine anti-tumor attributes of antigen-specific precision, potency and long-term persistence with reduced potential for off-target toxicities. NexImmune is focused on developing injectable AIM nanoparticle constructs and modalities for potential clinical evaluation in oncology, autoimmune disorders and infectious diseases.

For more information, visit www.neximmune.com.

Forward Looking Statements

This press release may contain "forward-looking" statements within the meaning of the Private Securities Litigation Reform Act of 1995 that are based on the beliefs and assumptions and on information currently available to management of NexImmune, Inc. (the "Company"). All statements other than statements of historical fact contained in this press release are forward-looking statements, including statements concerning the impact of our workforce reduction; the enrollment, timing, progress, release of data from and results of the Company's paused clinical trials and the expectations with respect to potential AIM INJ product candidates; the timing, progress and release of preclinical data from our AIM INJ platform programs and other preclinical research programs; the expectation of submitting an IND for NEXI-101 (injectable) in 2024; and the utility of prior preclinical and clinical data in determining future clinical results. In some cases, you can identify forward-looking statements by terminology such as "may," "will," "should," "expects," "plans," "anticipates," "believes," "estimates," "predicts," "potential" or "continue" or the negative of these terms or other comparable terminology. Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the Company's actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. These risks and uncertainties include, but are not limited to, the risks and uncertainties set forth in the "Risk Factors" section of our Annual Report on Form 10-K for the year ended December 31, 2022 filed with the Securities and Exchange Commission ("SEC") on March 28, 2023, and subsequent reports that we file with the SEC. Forward-looking statements represent the Company's beliefs and assumptions only as of the date of this press release. Although the Company believes that the expectations reflected in the forward-looking statements are reasonable, it cannot guarantee future results, levels of activity, performance or achievements. Except as required by law, the Company assumes no obligation to publicly update any forward-looking statements for any reason after the date of this press release to conform any of the forward-looking statements to actual results or to changes in its expectations.

Contacts

Investors:

Chad Rubin, SVP Corporate Affairs

NexImmune, Inc.

crubin@neximmune.com



Primary Logo

Get the next $NEXI alert in real time by email

Chat with this insight

Save time and jump to the most important pieces.

Recent Analyst Ratings for
$NEXI

DatePrice TargetRatingAnalyst
2/22/2022$21.00 → $13.00Outperform
Raymond James
11/15/2021$30.00 → $21.00Outperform
Raymond James
More analyst ratings

$NEXI
Press Releases

Fastest customizable press release news feed in the world

See more
  • NexImmune Announces Closing of $3.67 Million Registered Direct Offering Priced At-the-Market Under Nasdaq Rules

    GAITHERSBURG, Md., Feb. 06, 2024 (GLOBE NEWSWIRE) -- NexImmune, Inc. a biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted immune response by directing the function of antigen-specific T cells in oncology, autoimmune and infectious diseases, today announced the closing of its previously announced registered direct offering of 304,731 shares of its common stock (or common stock equivalents in lieu thereof) at a purchase price of $12.05 per share (or per common stock equivalent in lieu thereof) in a registered direct offering priced at-the-market under Nasdaq rules. In a concurrent private placement, the Company also issued unregistered warra

    $NEXI
    Biotechnology: Pharmaceutical Preparations
    Health Care
  • NexImmune Announces $3.67 Million Registered Direct Offering Priced At-the-Market Under Nasdaq Rules

    GAITHERSBURG, Md., Feb. 02, 2024 (GLOBE NEWSWIRE) -- NexImmune, Inc. a biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted immune response by directing the function of antigen-specific T cells in oncology, autoimmune and infectious diseases, today announced that it has entered into a definitive agreement with a single healthcare focused institutional investor for the issuance and sale of an aggregate of 304,731 of its shares of common stock (or common stock equivalents in lieu thereof) at a purchase price of $12.05 per share (or per common stock equivalent in lieu thereof) in a registered direct offering priced at-the-market under Nasdaq ru

    $NEXI
    Biotechnology: Pharmaceutical Preparations
    Health Care
  • NexImmune, Yale, and JDRF Extend Research Partnership for Type 1 Diabetes

    A JDRF funded grant is being used to explore the combination of NexImmune's antigen specific nanoparticles and an anti-CD3 mAb for prevention and treatment of type 1 diabetes GAITHERSBURG, Md., Oct. 24, 2023 (GLOBE NEWSWIRE) -- NexImmune, Inc. (NASDAQ:NEXI) announces the extension of the research partnership between NexImmune, Yale and JDRF to explore the use of NexImmune's AIM nanoparticles in combination with an anti-CD3 mAb to tolerize, deplete or modulate diabetes antigen-specific T cells. The extension includes an additional $300,000 grant, funded by JDRF to Yale, as a part of its Cures research portfolio, which includes therapies for the prevention of type 1 diabetes (T1D). "We

    $NEXI
    Biotechnology: Pharmaceutical Preparations
    Health Care

$NEXI
Analyst Ratings

Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

See more

$NEXI
Insider Purchases

Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

See more

$NEXI
Insider Trading

Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

See more

$NEXI
SEC Filings

See more

$NEXI
Leadership Updates

Live Leadership Updates

See more
  • NexImmune Reports First Quarter 2022 Financial Results and Provides Business Updates

    Clinical data updates for the Company's two lead product candidates in Phase 1/2 clinical trials expected in 2H2022Investigational New Drug (IND) submission for NEXI-003, the Company's first product for solid tumors, planned for 1H2022Plans to report additional preclinical and IND enabling data for the AIM Injectable platform in 2H2022 GAITHERSBURG, Md., May 12, 2022 (GLOBE NEWSWIRE) -- NexImmune, Inc. (NASDAQ:NEXI), a clinical-stage biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted immune response by directing the function of antigen-specific T cells, today reported financial results for the first quarter of 2022. "This quarter, we hav

    $NEXI
    Biotechnology: Pharmaceutical Preparations
    Health Care
  • NexImmune Announces Appointment of Dr. Leena Gandhi to its Board of Directors

    GAITHERSBURG, Md., May 10, 2022 (GLOBE NEWSWIRE) -- NexImmune, Inc. (NASDAQ:NEXI), a clinical-stage biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted immune response by directing the function of antigen-specific T cells, today announced the appointment of Leena Gandhi, M.D., Ph.D., Director for the Center of Therapeutic Innovation at Dana-Farber Cancer Institute, to its Board of Directors as a Non-Executive Director. "I am honored to join the board of NexImmune at this pivotal juncture in the Company's work," stated Dr. Gandhi. "I am excited to work with NexImmune's leadership on maximizing the potential of its novel technology in multip

    $NEXI
    Biotechnology: Pharmaceutical Preparations
    Health Care
  • NexImmune Appoints Kristi Jones as Chief Executive Officer and Member of the Board of Directors

    GAITHERSBURG, Md., Feb. 17, 2022 (GLOBE NEWSWIRE) -- NexImmune, Inc. (NASDAQ:NEXI), a clinical-stage biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted immune response by directing the function of antigen-specific T cells, today announced that Kristi Jones has been appointed as the Company's Chief Executive Officer and a member of its Board of Directors. Her appointment follows the departure of Scott Carmer, who submitted his letter of resignation this week.  "The Board is pleased to appoint Kristi Jones as our new Chief Executive Officer and member of the Board of Directors," said Sol J. Barer, Chairman of NexImmune's Board of Directors.

    $NEXI
    Biotechnology: Pharmaceutical Preparations
    Health Care

$NEXI
Financials

Live finance-specific insights

See more
  • NexImmune Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Business Updates

    Company has initiated pre-IND discussions with the FDA for its first AIM INJ indicationNEXI-001 completed enrollment in its final safety cohorts and all patients have been dosed; Company continues to follow patients and will announce data at or around an upcoming scientific conferenceCompany announces executive management changes as part of resource reallocation GAITHERSBURG, Md., March 28, 2023 (GLOBE NEWSWIRE) -- NexImmune, Inc. (NASDAQ:NEXI), a biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted immune response by directing the function of antigen-specific T cells for liquid and solid malignancies, today reported financial results for t

    $NEXI
    Biotechnology: Pharmaceutical Preparations
    Health Care
  • NexImmune Reports Third Quarter 2022 Financial Results and Announces Strategic Update

    Company announces a strategic shift to focus on advancing its AIM Direct Injection (AIM INJ) platform and potential product candidates in oncology and autoimmune diseasesInitiating a corporate resource reallocation to advance the AIM INJ platform, reduce operating expenses and extend cash runway through the third quarter of 2023 Pausing enrollment and initiation for the NEXI-001 and NEXI-003 trials, respectively, and pursuing external clinical development through potential academic and corporate partners GAITHERSBURG, Md., Nov. 14, 2022 (GLOBE NEWSWIRE) -- NexImmune, Inc. (NASDAQ:NEXI), a biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted

    $NEXI
    Biotechnology: Pharmaceutical Preparations
    Health Care
  • NexImmune Reports Second Quarter 2022 Financial Results and Highlights FDA Clearance of IND for NEXI-003 for the Treatment of HPV-Related Cancers

    Received U.S. Food and Drug Administration (FDA) clearance of Investigational New Drug (IND) submission for NEXI-003, the Company's first solid tumor product candidate for the treatment of HPV-related cancersPlans to report additional preclinical and IND enabling data for the AIM Injectable platform in 2H22Clinical updates for the Company's two lead product candidates in Phase 1/2 clinical trials expected in 4Q22Company is prioritizing resources to support Company's lead product candidates, NEXI-001 and NEXI-003 GAITHERSBURG, Md., Aug. 15, 2022 (GLOBE NEWSWIRE) -- NexImmune, Inc. (NASDAQ:NEXI), a clinical-stage biotechnology company developing a novel approach to immunotherapy designed t

    $NEXI
    Biotechnology: Pharmaceutical Preparations
    Health Care

$NEXI
Large Ownership Changes

This live feed shows all institutional transactions in real time.

See more