Oculis Announces Topline Results From Its Phase 2b RELIEF Trial With Licaminlimab, A Novel Anti-Tnfα Biologic Eye Drop
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Biotechnology: Pharmaceutical Preparations
Health Care
- Improvements in multiple sign efficacy endpoints were observed in full population and with predictive and more pronounced effects in the TNFR1 genetic biomarker population as identified in prior successful Phase 2 symptoms trial
- Rapid treatment effect on corneal inflammation was observed in TNFR1 genetic biomarker patients as early as Day 15 and was statistically significant at final efficacy visit on Day 43
- Licaminlimab was well tolerated similar to vehicle
- Company plans to finalize Phase 3 development plans following an End-of-Phase 2 (EoP2) meeting with the U.S. Food and Drug Administration (FDA)