• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Dashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlerts
    Company
    AboutQuantisnow PlusContactJobs
    Legal
    Terms of usePrivacy policyCookie policy

    Prometheus Biosciences Inc. filed SEC Form 8-K: Completion of Acquisition or Disposition of Assets, Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Material Modification to Rights of Security Holders, Changes in Control of Registrant, Leadership Update, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

    6/16/23 8:52:01 AM ET
    $RXDX
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $RXDX alert in real time by email
    8-K
    false 0001718852 --12-31 0001718852 2023-06-16 2023-06-16

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    FORM 8-K

     

     

    CURRENT REPORT

    Pursuant to Section 13 or 15(d)

    of the Securities Exchange Act of 1934

    Date of Report (Date of earliest event reported): June 16, 2023

     

     

    PROMETHEUS BIOSCIENCES, INC.

    (Exact Name of Registrant as Specified in Charter)

     

     

     

    Delaware   001-40187   81-4282653

    (State or Other Jurisdiction

    of Incorporation)

     

    (Commission

    File Number)

     

    (IRS Employer

    Identification No.)

     

    3050 Science Park Road
    San Diego, CA
      92121
    (Address of Principal Executive Offices)   (Zip Code)

    (858) 422-4300

    (Registrant’s telephone number, including area code)

    Not applicable

    (Former Name or Former Address, if Changed Since Last Report)

     

     

    Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

     

    ☐

    Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

     

    ☐

    Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

     

    ☐

    Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

     

    ☐

    Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

    Securities registered pursuant to Section 12(b) of the Act:

     

    Title of each class

     

    Trading
    Symbol(s)

     

    Name of each exchange

    on which registered

    Common Stock, $0.0001 par value per share   RXDX   The Nasdaq Global Select Market

    Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

    Emerging growth company ☐

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

     

     

     


    Item 2.01

    Completion of Acquisition or Disposition of Assets.

    On June 16, 2023 (the “Closing Date”), Prometheus Biosciences, Inc., a Delaware corporation (“Prometheus”), completed the previously announced merger of Splash Merger Sub, Inc., a Delaware corporation (“Merger Sub”) and a wholly owned subsidiary of Merck & Co., Inc., a New Jersey corporation (“Merck”), with and into Prometheus (the “Merger”), with Prometheus surviving the Merger as a wholly owned subsidiary of Merck. The Merger was effectuated pursuant to the Agreement and Plan of Merger, dated as of April 15, 2023 (the “Merger Agreement”), by and among Merck, Merger Sub and Prometheus, as previously disclosed by Prometheus on April 17, 2023 in a Current Report on Form 8-K filed with the Securities and Exchange Commission (“SEC”).

    Pursuant to the Merger Agreement, at the effective time of the Merger (the “Effective Time”), each of the issued and outstanding shares of Prometheus common stock, par value $0.0001 per share (“Prometheus Common Stock”), other than any shares of Prometheus Common Stock (i) owned immediately prior to the Effective Time by Merck, Merger Sub or Prometheus or by any direct or indirect wholly owned subsidiary of Merck, Merger Sub or Prometheus or (ii) owned by Prometheus stockholders who are entitled to demand and have properly and validly demanded their appraisal rights under Delaware law, was canceled and extinguished and automatically converted into the right to receive $200.00 per share in cash (the “Merger Consideration”), without interest and subject to any applicable withholding taxes.

    In addition, at the Effective Time, (i) each outstanding Prometheus stock option, whether vested or unvested, was automatically canceled and converted into the right to receive an amount in cash, without interest, equal to the product of (A) the number of shares of Prometheus Common Stock underlying such option immediately prior to the Effective Time multiplied by (B) the amount, if any, by which the Merger Consideration exceeded the exercise price per share of such option, (ii) each outstanding Prometheus restricted stock unit (“RSU”) was automatically canceled and converted into the right to receive an amount in cash equal to the product of (A) the number of shares of Prometheus Common Stock underlying such RSU immediately prior to the Effective Time multiplied by (B) the Merger Consideration, without interest and subject to any applicable withholding taxes, and (iii) each outstanding share of restricted stock of Prometheus automatically became fully vested and was converted into the right to receive the Merger Consideration.

    Prometheus’ definitive proxy statement, filed with the SEC on May 16, 2023, as supplemented on June 6, 2023 (the “Proxy Statement”), contains additional information about the Merger and the Merger Agreement, including information concerning the interests of directors, executive officers and affiliates of Prometheus in the Merger.

    The foregoing description of the Merger Agreement contained in this Item 2.01 does not purport to be complete and is subject to, and qualified in its entirety by, the full text of the Merger Agreement. A copy of the Merger Agreement was filed as Exhibit 2.1 to the Current Report on Form 8-K filed by Prometheus with the SEC on April 17, 2023, and is incorporated by reference into this Item 2.01.

     

    Item 3.01

    Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing.

    In connection with the consummation of the Merger, Prometheus requested that The NASDAQ Stock Market LLC (“NASDAQ”) suspend trading of Prometheus Common Stock prior to the opening of trading on June 16, 2023 and file with the SEC an application on Form 25 to delist and deregister Prometheus Common Stock under Section 12(b) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). The delisting of Prometheus Common Stock from NASDAQ will be effective 10 days after the filing of the Form 25. Following the effectiveness of such Form 25, Prometheus


    intends to file with the SEC a certification on Form 15 requesting the termination of registration of the Prometheus Common Stock under Section 12(g) of the Exchange Act and the suspension of Prometheus’ reporting obligations under Sections 13 and 15(d) of the Exchange Act with respect to Prometheus Common Stock.

    The information set forth in Item 2.01 of this report is incorporated by reference into this Item 3.01.

     

    Item 3.03

    Material Modification to Rights of Security Holders.

    The information set forth in Items 2.01, 3.01 and 5.03, respectively, of this report is incorporated by reference into this Item 3.03.

     

    Item 5.01

    Changes in Control of Registrant.

    As a result of the consummation of the Merger, a change of control of Prometheus occurred on the Closing Date and Prometheus became a wholly owned subsidiary of Merck. Merck funded the acquisition through the use of cash on hand, commercial paper or existing or new credit facilities, as described in the Proxy Statement.

    The information set forth in Items 2.01, 3.03, 5.02 and 5.03, respectively, of this report is incorporated by reference into this Item 5.01.

     

    Item 5.02

    Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

    The information set forth in Item 2.01 is incorporated by reference into this Item 5.02.

    Pursuant to the Merger Agreement, as of the Effective Time, each of the directors of Prometheus (Mark C. McKenna, Helen C. Adams, Fred Hassan, Martin Hendrix, Ph.D., James Laur, Joseph C. Papa, Judith L. Swain, M.D. and Mary Szela) resigned from the board of directors of Prometheus. At the Effective Time, Jon Filderman, Rita Karachun and Aaron Rosenberg, each a director of Merger Sub immediately prior to the Effective Time, became directors of Prometheus.

    In connection with the Merger, at the Effective Time, Mark C. McKenna, Keith W. Marshall, Ph.D. and Mark Stenhouse ceased to be executive officers of Prometheus. In accordance with the terms of the Merger Agreement, at the Effective Time, the officers of Merger Sub became the officers of Prometheus.

     

    Item 5.03

    Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year.

    The information set forth in Item 2.01 is incorporated by reference into this Item 5.03.

    Pursuant to the Merger Agreement, as of the Effective Time, the certificate of incorporation of Prometheus, as in effect immediately prior to the Effective Time, was amended and restated in its entirety (the “Amended and Restated Certificate of Incorporation”). The Amended and Restated Certificate of Incorporation is filed as Exhibit 3.1 hereto and incorporated by reference into this Item 5.03.

    In addition, as of the Effective Time, in accordance with the Merger Agreement, the bylaws of Prometheus, as in effect immediately prior to the Effective Time, were amended and restated in their entirety (the “Bylaws”). The Bylaws, as so amended and restated, are filed as Exhibit 3.2 hereto and incorporated by reference into this Item 5.03.


    Item 9.01

    Financial Statements and Exhibits.

    (d) Exhibits.

     

    Exhibit

    No.

       Description
    2.1    Agreement and Plan of Merger, dated as of April 15, 2023, by and among Prometheus Biosciences, Inc., Merck & Co., Inc. and Splash Merger Sub, Inc. (incorporated by reference to Exhibit 2.1 to Prometheus’ Current Report on Form 8-K filed on April 17, 2023)*
    3.1    Amended and Restated Certificate of Incorporation of Prometheus Biosciences, Inc.
    3.2    Amended and Restated Bylaws of Prometheus Biosciences, Inc.
    104    Cover Page Interactive Data File – the cover page XBRL tags are embedded within the Inline XBRL document

     

    *

    Certain exhibits and schedules have been omitted pursuant to Item 601(a)(5) of Regulation S-K. Prometheus hereby undertakes to furnish supplemental copies of any of the omitted exhibits and schedules upon request by the SEC; provided, however, that Prometheus may request confidential treatment pursuant to Rule 24b-2 of the Exchange Act for any exhibits or schedules so furnished.


    SIGNATURES

    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

     

    Dated: June 16, 2023   PROMETHEUS BIOSCIENCES, INC.
        By:  

    /s/ Kelly E.W. Grez

        Name:   Kelly E.W. Grez
        Title:   Secretary
    Get the next $RXDX alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $RXDX

    DatePrice TargetRatingAnalyst
    5/10/2023$160.00 → $200.00Buy → Hold
    Jefferies
    7/20/2022$51.00Buy
    Goldman
    6/10/2022$53.00Overweight
    Piper Sandler
    3/10/2022$50.00 → $52.00Outperform
    Credit Suisse
    3/10/2022$42.00 → $53.00Overweight
    Wells Fargo
    3/10/2022$47.00 → $55.00Outperform
    SVB Leerink
    2/11/2022$62.00Buy
    BTIG
    12/13/2021$46.00Outperform
    RBC Capital Mkts
    More analyst ratings

    $RXDX
    Leadership Updates

    Live Leadership Updates

    See more
    • Cellino Appoints Chris Gibson to Board of Directors

      Cellino Biotech, Inc., a biotechnology company advancing autonomous, closed biomanufacturing for personalized regenerative medicines, today announced the appointment of Chris Gibson to the company's Board of Directors. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20241024933617/en/Chris Gibson, Ph.D., Co-Founder & CEO, Recursion. (Photo credit: Recursion) Chris Gibson, Ph.D., is the Co-Founder and CEO of Recursion (NASDAQ:RXDX), a clinical-stage techbio company at the forefront of AI-driven drug discovery. Dr. Gibson has led a number of key partnerships for Recursion with leading pharma and tech companies, including Roche/Genente

      10/24/24 8:00:00 AM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Prometheus Biosciences Reports Second Quarter 2021 Financial Results and Highlights Recent Corporate Progress

      - Initiated Phase 2 study of PRA023 and its companion diagnostic in Ulcerative Colitis (UC) and Phase 2a study of PRA023 and its companion diagnostic in Crohn's disease (CD) - - Phase 1a trial results of PRA023 in normal healthy volunteers expected in fourth quarter 2021 - - Strong cash position of $304 million as of June 30, 2021 - SAN DIEGO, Aug. 11, 2021 (GLOBE NEWSWIRE) -- Prometheus Biosciences, Inc. (NASDAQ:RXDX), a clinical-stage biotechnology company pioneering a precision medicine approach for the discovery, development, and commercialization of novel therapeutic and companion diagnostic products for the treatment of immune-mediated diseases, starting first with inflammatory bo

      8/11/21 4:01:00 PM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Psychedelic Science Leader Eleusis Announces Four New Board Appointments, Further Strengthening Leadership

      Eleusis, a clinical-stage life science company dedicated to unlocking the full therapeutic potential of psychedelics, today announced the appointment of four highly experienced business leaders to its board of directors. The new directors' deep expertise building high-growth, high-impact life science companies complements Eleusis's world-class leadership team. The appointees include: David Socks, former CEO of Phathom Pharmaceuticals, joining as Chair of the board Robert Hershberg, M.D., Ph.D., former CBO and CSO of Celgene John Tucker, CEO of SC Pharmaceuticals Esther van den Boom, Managing Partner at van den Boom & Associates "We are delighted to welcome these four exceptional d

      7/12/21 8:00:00 AM ET
      $RXDX
      $PASG
      $PHAT
      $ARQT
      Biotechnology: Pharmaceutical Preparations
      Health Care
      Biotechnology: Biological Products (No Diagnostic Substances)

    $RXDX
    SEC Filings

    See more
    • SEC Form 15-12G filed by Prometheus Biosciences Inc.

      15-12G - Prometheus Biosciences, Inc. (0001718852) (Filer)

      6/27/23 3:06:42 PM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 25-NSE filed by Prometheus Biosciences Inc.

      25-NSE - Prometheus Biosciences, Inc. (0001718852) (Subject)

      6/16/23 9:13:06 AM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form S-8 POS filed by Prometheus Biosciences Inc.

      S-8 POS - Prometheus Biosciences, Inc. (0001718852) (Filer)

      6/16/23 9:12:56 AM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $RXDX
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Cellino Appoints Chris Gibson to Board of Directors

      Cellino Biotech, Inc., a biotechnology company advancing autonomous, closed biomanufacturing for personalized regenerative medicines, today announced the appointment of Chris Gibson to the company's Board of Directors. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20241024933617/en/Chris Gibson, Ph.D., Co-Founder & CEO, Recursion. (Photo credit: Recursion) Chris Gibson, Ph.D., is the Co-Founder and CEO of Recursion (NASDAQ:RXDX), a clinical-stage techbio company at the forefront of AI-driven drug discovery. Dr. Gibson has led a number of key partnerships for Recursion with leading pharma and tech companies, including Roche/Genente

      10/24/24 8:00:00 AM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Merck Completes Acquisition of Prometheus Biosciences, Inc.

      Acquisition delivers industry-leading research capability, and strengthens pipeline with a novel candidate for ulcerative colitis, Crohn's disease and other autoimmune conditions Merck (NYSE:MRK), known as MSD outside of the United States and Canada, today announced the completion of the Prometheus Biosciences, Inc. ("Prometheus") (NASDAQ:RXDX) acquisition. Prometheus is now a wholly-owned subsidiary of Merck and the common stock of Prometheus will no longer be listed or traded on the Nasdaq Global Market. "The Prometheus acquisition accelerates our growing presence in immunology, augments our diverse pipeline and increases our ability to deliver patient value. This transaction is anoth

      6/16/23 4:04:00 PM ET
      $MRK
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Prometheus Biosciences Reports First Quarter 2023 Financial Results and Highlights Recent Corporate Progress

      SAN DIEGO, May 09, 2023 (GLOBE NEWSWIRE) -- Prometheus Biosciences, Inc. (NASDAQ:RXDX), a clinical-stage biotechnology company pioneering a precision medicine approach for the discovery, development, and commercialization of novel therapeutics for the treatment of immune-mediated diseases, today reported financial results for the quarter ended March 31, 2023. Prometheus to be Acquired by Merck On April 15, 2023, Merck and Prometheus Biosciences entered into a definitive agreement under which Merck, through a subsidiary, has agreed to acquire Prometheus for $200.00 per share in cash for a total equity value of approximately $10.8 billion. The transaction is expected to close in the th

      5/9/23 4:00:00 PM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $RXDX
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • SEC Form SC 13G/A filed by Prometheus Biosciences Inc. (Amendment)

      SC 13G/A - Prometheus Biosciences, Inc. (0001718852) (Subject)

      3/8/23 5:02:07 PM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Prometheus Biosciences Inc. (Amendment)

      SC 13G/A - Prometheus Biosciences, Inc. (0001718852) (Subject)

      2/14/23 4:27:18 PM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Prometheus Biosciences Inc. (Amendment)

      SC 13G/A - Prometheus Biosciences, Inc. (0001718852) (Subject)

      2/14/23 3:01:42 PM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $RXDX
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Prometheus Biosciences downgraded by Jefferies with a new price target

      Jefferies downgraded Prometheus Biosciences from Buy to Hold and set a new price target of $200.00 from $160.00 previously

      5/10/23 6:31:59 AM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Goldman initiated coverage on Prometheus Biosciences with a new price target

      Goldman initiated coverage of Prometheus Biosciences with a rating of Buy and set a new price target of $51.00

      7/20/22 7:36:43 AM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Piper Sandler initiated coverage on Prometheus Biosciences with a new price target

      Piper Sandler initiated coverage of Prometheus Biosciences with a rating of Overweight and set a new price target of $53.00

      6/10/22 7:19:39 AM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $RXDX
    Financials

    Live finance-specific insights

    See more
    • Prometheus Biosciences Announces Positive Results for PRA023 in Both ARTEMIS-UC Phase 2 and APOLLO-CD Phase 2a Studies Enabling Pathway to Both First-in-Class and Best-in-Class Anti-TL1A mAb

      – ARTEMIS-UC trial met primary endpoint with 26.5% of patients on PRA023 achieving clinical remission compared to 1.5% of patients on placebo at Week 12 (p<0.0001) – – ARTEMIS-UC Cohort 1 met all ranked secondary endpoints – – APOLLO-CD trial showed 26.0% endoscopic response and 49.1% clinical remission rates (p=0.002 and p<0.001, respectively, compared to prespecified historical placebo rates) – – PRA023 demonstrated favorable safety and tolerability results across both studies with no safety signal identified – – ARTEMIS-UC Cohort 1 interim analysis suggests a trend towards increased PRA023 response in CDx+ patients over all comers – – PRA023 showed a significant impact on multiple m

      12/7/22 7:00:00 AM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Prometheus Biosciences Reports Positive Topline Phase 1 Data on Lead Therapeutic Candidate PRA023; Expands Indications to Include Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)

      Phase 1 trial achieved primary objective of safety and tolerability and demonstrated favorable outcomes on other key endpoints, including target engagement and immunogenicity Discussion of Phase 1 results and rationale around SSc-ILD as new PRA023 indication to be presented in conference call scheduled today at 8:00 AM EST SAN DIEGO, Dec. 07, 2021 (GLOBE NEWSWIRE) -- Prometheus Biosciences, Inc. (NASDAQ:RXDX), a clinical-stage biotechnology company pioneering a precision medicine approach for the discovery, development and commercialization of novel therapeutic and companion diagnostic products for the treatment of immune-mediated diseases, today reported positive topline results fro

      12/7/21 7:00:00 AM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $RXDX
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • SEC Form 4 filed by Mckenna Mark C.

      4 - Prometheus Biosciences, Inc. (0001718852) (Issuer)

      6/16/23 4:00:25 PM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Stenhouse Mark

      4 - Prometheus Biosciences, Inc. (0001718852) (Issuer)

      6/16/23 4:00:32 PM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Hendrix Martin

      4 - Prometheus Biosciences, Inc. (0001718852) (Issuer)

      6/16/23 4:00:40 PM ET
      $RXDX
      Biotechnology: Pharmaceutical Preparations
      Health Care