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    SEC Form 10-K filed by Septerna Inc.

    3/27/25 8:25:34 AM ET
    $SEPN
    Biotechnology: Pharmaceutical Preparations
    Health Care
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    Recent Analyst Ratings for
    $SEPN

    DatePrice TargetRatingAnalyst
    2/18/2025$14.00Overweight → Equal Weight
    Wells Fargo
    11/19/2024$38.00Overweight
    Analyst
    11/19/2024Buy
    TD Cowen
    11/19/2024$43.00Overweight
    Wells Fargo
    11/19/2024$50.00Overweight
    Cantor Fitzgerald
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    $SEPN
    Insider Purchases

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    • Director Ezekowitz Alan bought $92,270 worth of shares (13,319 units at $6.93), increasing direct ownership by 13% to 117,420 units (SEC Form 4)

      4 - Septerna, Inc. (0001984086) (Issuer)

      3/10/25 4:18:19 PM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Ezekowitz Alan bought $515,934 worth of shares (86,681 units at $5.95), increasing direct ownership by 498% to 104,101 units (SEC Form 4)

      4 - Septerna, Inc. (0001984086) (Issuer)

      3/6/25 9:02:51 PM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • CEO and President Finer Jeffrey bought $96,961 worth of shares (17,000 units at $5.70), increasing direct ownership by 2% to 771,907 units (SEC Form 4)

      4 - Septerna, Inc. (0001984086) (Issuer)

      2/27/25 6:53:01 PM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SEPN
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    • Septerna Expands Leadership with Appointment of Industry Veteran Gil Labrucherie as Chief Financial Officer

      SOUTH SAN FRANCISCO, Calif., Jan. 06, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (NASDAQ:SEPN), a clinical-stage biotech company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced the appointment of Gil Labrucherie, CFA, J.D., as Chief Financial Officer. Mr. Labrucherie is a seasoned biopharma executive with more than 25 years of senior leadership experience in finance and legal roles for public biopharmaceutical and technology companies. "We are excited to welcome Gil to the team," said Jeffrey Finer, M.D., Ph.D., Chief Executive Officer and Co-founder of Septerna. "His extensive expertise leading public company finance and capital strategy will be ins

      1/6/25 7:00:00 AM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SEPN
    SEC Filings

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    • SEC Form DEFA14A filed by Septerna Inc.

      DEFA14A - Septerna, Inc. (0001984086) (Filer)

      4/29/25 4:08:35 PM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEF 14A filed by Septerna Inc.

      DEF 14A - Septerna, Inc. (0001984086) (Filer)

      4/29/25 4:05:26 PM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form S-8 filed by Septerna Inc.

      S-8 - Septerna, Inc. (0001984086) (Filer)

      3/27/25 8:51:02 AM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SEPN
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    • CEO and President Finer Jeffrey exercised 55,000 shares at a strike of $2.76, increasing direct ownership by 7% to 826,907 units (SEC Form 4)

      4 - Septerna, Inc. (0001984086) (Issuer)

      4/4/25 4:13:25 PM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Ezekowitz Alan bought $92,270 worth of shares (13,319 units at $6.93), increasing direct ownership by 13% to 117,420 units (SEC Form 4)

      4 - Septerna, Inc. (0001984086) (Issuer)

      3/10/25 4:18:19 PM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Director Ezekowitz Alan bought $515,934 worth of shares (86,681 units at $5.95), increasing direct ownership by 498% to 104,101 units (SEC Form 4)

      4 - Septerna, Inc. (0001984086) (Issuer)

      3/6/25 9:02:51 PM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SEPN
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    • Septerna downgraded by Wells Fargo with a new price target

      Wells Fargo downgraded Septerna from Overweight to Equal Weight and set a new price target of $14.00

      2/18/25 8:55:10 AM ET
      $SEPN
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    • Analyst initiated coverage on Septerna with a new price target

      Analyst initiated coverage of Septerna with a rating of Overweight and set a new price target of $38.00

      11/19/24 7:39:27 AM ET
      $SEPN
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    • TD Cowen initiated coverage on Septerna

      TD Cowen initiated coverage of Septerna with a rating of Buy

      11/19/24 7:39:11 AM ET
      $SEPN
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    • Septerna Provides Corporate Overview and Reports Fourth Quarter and Full Year 2024 Financial Results

      Preclinical Work Advancing with Plans to Select a Next-Generation Oral Small Molecule PTH1R Agonist to Accelerate Toward the Clinic Later This Year Phase 1 Trial for SEP-631, MRGPRX2 NAM Program for Mast Cell Diseases, Expected to Initiate in 2025 Well-Capitalized with $420.8M Balance Sheet as of YE 2024 to Support Operating Runway into Early 2028 SOUTH SAN FRANCISCO, Calif., March 27, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (NASDAQ:SEPN), a biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today provided a corporate overview complete with upcoming milestones and reported fourth quarter and full year 2024 financial results. "Our Native Comp

      3/27/25 8:00:00 AM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
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    • Septerna to Present at TD Cowen 45th Annual Health Care Conference

      SOUTH SAN FRANCISCO, Calif., Feb. 26, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (NASDAQ:SEPN), a biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug discovery, today announced that Jeffrey Finer, M.D., Ph.D., Chief Executive Officer and Co-founder of Septerna, will present at the TD Cowen 45th Annual Health Care Conference on Wednesday, March 5, 2025, at 10:30 a.m. ET in Boston. About SepternaSepterna, Inc. is a biotechnology company pioneering a new era of GPCR drug discovery powered by its proprietary Native Complex Platform™. Its industrial-scale platform aims to unlock the full potential of GPCR therapies and has led to the discovery and development

      2/26/25 8:00:00 AM ET
      $SEPN
      Biotechnology: Pharmaceutical Preparations
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    • Septerna Announces Discontinuation of SEP-786 Phase 1 Clinical Trial and Plans to Advance Next-Generation Oral Small Molecule PTH1R Agonist

      Trial decision follows unanticipated events of elevated unconjugated bilirubin levels Company advancing multiple next-generation PTH1R agonists with distinct and unrelated chemical structures relative to SEP-786 SOUTH SAN FRANCISCO, Calif., Feb. 18, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (NASDAQ:SEPN), a clinical-stage biotechnology company pioneering a new era of GPCR drug discovery, today announced its decision to discontinue the Phase 1 single- and multiple-ascending dose (SAD/MAD) clinical trial of SEP-786 in healthy volunteers. SEP-786 is an oral small molecule agonist of the parathyroid hormone 1 receptor (PTH1R) being developed for the treatment of hypoparathyroidism.

      2/18/25 8:00:00 AM ET
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    • SEC Form SC 13D filed by Septerna Inc.

      SC 13D - Septerna, Inc. (0001984086) (Subject)

      11/4/24 4:39:38 PM ET
      $SEPN
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    • SEC Form SC 13G filed by Septerna Inc.

      SC 13G - Septerna, Inc. (0001984086) (Subject)

      11/4/24 4:15:38 PM ET
      $SEPN
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    • SEC Form SC 13G filed by Septerna Inc.

      SC 13G - Septerna, Inc. (0001984086) (Subject)

      11/1/24 4:27:45 PM ET
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