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    SEC Form 10-Q filed by Quantum-Si Incorporated

    5/15/25 4:36:31 PM ET
    $QSI
    Industrial Machinery/Components
    Industrials
    Get the next $QSI alert in real time by email
    qsi-20250331
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    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549
    _____________________________________________________________
    FORM 10-Q
    (Mark One)
    ☒
    QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
    For the quarterly period ended March 31, 2025
    or
    o
    TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
    For the transition period from ________ to _________
    Commission File Number: 001-39486
    QUANTUM-SI INCORPORATED
    (Exact name of registrant as specified in its charter)
    _____________________________________________________________
    Delaware
    85-1388175
    (State or other jurisdiction of incorporation or organization)(I.R.S. Employer Identification No.)
    29 Business Park Drive
    Branford, Connecticut
    06405
    (Address of principal executive offices)(Zip Code)
    (866) 688-7374
    (Registrant’s telephone number, including area code)
    Not applicable
    (Former name, former address and former fiscal year, if changed since last report)
    Securities registered pursuant to Section 12(b) of the Act:
    Title of each class
    Trading
     Symbol(s)
    Name of each exchange on which registered
    Class A common stock, $0.0001 per shareQSIThe Nasdaq Stock Market LLC
    Redeemable warrants, each whole warrant exercisable for one share of Class A common stock, each at an exercise price of $11.50 per shareQSIAWThe Nasdaq Stock Market LLC
    Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No o
    Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒ No o
    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
    Large accelerated fileroAccelerated filero
    Non-accelerated filer☒Smaller reporting company☒
    Emerging growth companyo
    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o
    Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒
    As of May 9, 2025, the registrant had 163,560,616 shares of Class A common stock outstanding and 19,937,500 shares of Class B common stock outstanding.



    QUANTUM-SI INCORPORATED
    TABLE OF CONTENTS

    Page
    Cautionary Note Regarding Forward-Looking Statements
    3
    Part I.
    Financial Information
    5
    Item 1.
    Financial Statements
    5
    Condensed Consolidated Balance Sheets as of March 31, 2025, and December 31, 2024 (unaudited)
    5
    Condensed Consolidated Statements of Operations and Comprehensive Loss for the three months ended March 31, 2025 and 2024 (unaudited)
    6
    Condensed Consolidated Statements of Changes in Stockholders’ Equity for the three months ended March 31, 2025 and 2024 (unaudited)
    7
    Condensed Consolidated Statements of Cash Flows for the three months ended March 31, 2025 and 2024 (unaudited)
    8
    Notes to Condensed Consolidated Financial Statements (unaudited)
    9
    Item 2.
    Management’s Discussion and Analysis of Financial Condition and Results of Operations
    24
    Item 3.
    Quantitative and Qualitative Disclosures About Market Risk
    30
    Item 4.
    Controls and Procedures
    31
    Part II.
    Other Information
    32
    Item 1.
    Legal Proceedings
    32
    Item 1A.
    Risk Factors
    32
    Item 2.
    Unregistered Sales of Equity Securities and Use of Proceeds
    32
    Item 3.
    Defaults Upon Senior Securities
    32
    Item 4.
    Mine Safety Disclosures
    32
    Item 5.
    Other Information
    33
    Item 6.
    Exhibits
    34
    Signatures
    35
    In this Quarterly Report on Form 10-Q, the terms “we”, “us”, “our”, the “Company” or “Quantum-Si” mean Quantum-Si Incorporated and our subsidiaries. Quantum-Si Incorporated was incorporated in Delaware on June 10, 2020.
    2

    Table of Contents
    CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS
    This Quarterly Report on Form 10-Q includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), that relate to future events, our future operations or financial performance, or our plans, strategies and prospects. These statements are based on the beliefs and assumptions of our management team. Although we believe that our plans, intentions and expectations reflected in or suggested by these forward-looking statements are reasonable, we cannot assure that we will achieve or realize these plans, intentions or expectations. Forward-looking statements are inherently subject to risks, uncertainties and assumptions. Generally, statements that are not historical facts, including statements concerning possible or assumed future actions, business strategies, events or performance, are forward-looking statements. The actual results may differ from its expectations, estimates, and projections and, consequently, you should not rely on these forward-looking statements as predictions of future events. Words such as “expect,” “estimate,” “project,” “budget,” “forecast,” “anticipate,” “intend,” “plan,” “may,” “will,” “could,” “should,” “believes,” “predicts,” “potential,” “continue,” and similar expressions (or the negative versions of such words or expressions) are intended to identify such forward-looking statements. These forward-looking statements include, without limitation, our expectations with respect to future performance and development and commercialization of products and services. The forward-looking statements are based on projections prepared by, and are the responsibility of, management and involve significant risks and uncertainties that could cause the actual results to differ materially from those discussed in the forward-looking statements. Most of these factors are outside our control and are difficult to predict. Forward-looking statements contained in this Quarterly Report on Form 10-Q include, but are not limited to, statements about:
    •the impact of international conflicts, pandemics or epidemics on our business;
    •the impact of general conditions in the global economy and in the global financial markets, including changes in inflation, interest rates, tariffs, retaliatory trade policies including limitations of shipments of products, and overall economic conditions and uncertainties;
    •maintaining the listing of our Class A common stock on The Nasdaq Stock Market LLC;
    •changes in applicable laws or regulations;
    •our ability to raise financing in the future;
    •the success, cost and timing of our product development and commercialization activities;
    •the commercialization and adoption of our existing products, including our Platinum® line of instruments, our consumable kits and the success of any product we may offer in the future;
    •our ability to obtain and maintain regulatory approval for our products, and any related restrictions and limitations of any approved product;
    •our ability to identify, in-license or acquire additional technology;
    •our ability to maintain our existing lease, license, manufacture and supply agreements;
    •our ability to compete with other companies currently marketing or engaged in the development or commercialization of products and services that serve customers engaged in proteomic analysis, many of which have greater financial and marketing resources than us;
    •the size and growth potential of the markets for our products and services, and our ability to serve those markets once commercialized, either alone or in partnership with others;
    •our estimates regarding future expenses, future revenue, capital requirements and needs for additional financing; and
    •our financial performance.
    These forward-looking statements are based on information available as of the date of this report and current expectations, forecasts and assumptions, and involve a number of judgments, risks and uncertainties. Important factors could cause actual results, performance or achievements to differ materially from those indicated or implied by forward-looking statements such as those described in Part I, Item 1A, “Risk Factors” of our Annual Report on Form 10-K for the fiscal year ended December 31, 2024, this Quarterly Report on Form 10-Q, and in other filings that we make with the Securities and Exchange Commission. The risks described under the heading “Risk Factors” are not exhaustive. New risk factors emerge from time to time, and it is not possible to predict all such risk factors, nor can we assess the impact of all such risk factors on our business or the extent to which any factor or combination of factors may cause actual results to differ materially from those contained in any forward-looking statements. Forward-looking statements are not guarantees of performance. You should not put undue reliance on these statements, which speak only as of the date hereof. All forward-looking statements attributable to us or persons acting on our behalf are expressly qualified in their entirety by the
    3

    Table of Contents
    foregoing cautionary statements. We undertake no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.
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    PART I – FINANCIAL INFORMATION
    Item 1.    Financial Statements
    QUANTUM-SI INCORPORATED
    CONDENSED CONSOLIDATED BALANCE SHEETS
    (in thousands, except share and par value amounts)
    (unaudited)
    March 31,
    2025
    December 31,
    2024
    Assets
    Current assets:
    Cash and cash equivalents$37,293 $49,241 
    Marketable securities195,308 160,362 
    Accounts receivable, net of allowance of $124 and $124, respectively
    1,032 1,333 
    Inventory4,423 4,067 
    Prepaid expenses and other current assets3,749 3,006 
    Total current assets241,805 218,009 
    Property and equipment, net16,179 15,993 
    Operating lease right-of-use assets12,430 13,061 
    Other assets808 808 
    Total assets$271,222 $247,871 
    Liabilities and stockholders’ equity  
    Current liabilities:  
    Accounts payable$1,894 $1,931 
    Accrued payroll and payroll-related costs2,133 5,331 
    Accrued contracted services2,766 2,379 
    Accrued expenses and other current liabilities3,840 4,848 
    Current portion of operating lease liabilities
    1,936 3,698 
    Total current liabilities12,569 18,187 
    Warrant liabilities1,594 4,995 
    Operating lease liabilities10,118 9,250 
    Other long-term liabilities
    21 19 
    Total liabilities24,302 32,451 
    Commitments and contingencies (Note 17)
    Stockholders’ equity:
    Class A Common stock, $0.0001 par value; 600,000,000 shares authorized as of March 31, 2025 and December 31, 2024; 163,560,616 and 146,953,271 shares issued and outstanding as of March 31, 2025 and December 31, 2024, respectively
    16 16 
    Class B Common stock, $0.0001 par value; 27,000,000 shares authorized as of March 31, 2025 and December 31, 2024; 19,937,500 shares issued and outstanding as of March 31, 2025 and December 31, 2024
    2 2 
    Additional paid-in capital862,734 811,998 
    Accumulated other comprehensive (loss) income(2)45 
    Accumulated deficit(615,830)(596,641)
    Total stockholders’ equity
    246,920 215,420 
    Total liabilities and stockholders’ equity
    $271,222 $247,871 
    The accompanying notes are an integral part of these Condensed Consolidated Financial Statements.
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    QUANTUM-SI INCORPORATED
    CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
    (in thousands, except per share amounts)
    (unaudited)
    Three months ended March 31,
    20252024
    Revenue
    Product$808 $428 
    Service34 29 
    Total revenue842 457 
    Cost of revenue
    Product337 170 
    Service19 18 
    Total cost of revenue356 188 
    Gross profit486 269 
    Operating expenses:
    Research and development13,717 12,101 
    Selling, general and administrative11,881 11,528 
    Total operating expenses25,598 23,629 
    Loss from operations(25,112)(23,360)
    Dividend and interest income2,547 3,574 
    Change in fair value of warrant liabilities3,401 319 
    Other expense, net(14)(7)
    Loss before provision for income taxes(19,178)(19,474)
    Provision for income taxes(11)— 
    Net loss$(19,189)$(19,474)
    Net loss per common share attributable to common stockholders, basic and diluted$(0.11)$(0.14)
    Weighted-average shares used to compute net loss per share attributable to common stockholders, basic and diluted182,303141,773
    Other comprehensive (loss) income:
    Net unrealized loss on marketable securities, net of tax$(53)$(28)
    Foreign currency translation adjustment6 (5)
    Total other comprehensive loss, net of tax(47)(33)
    Comprehensive loss$(19,236)$(19,507)

    The accompanying notes are an integral part of these Condensed Consolidated Financial Statements.
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    QUANTUM-SI INCORPORATED
    CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS’ EQUITY
    (in thousands, except share amounts)
    (unaudited)
     Class A
    common stock
    Class B
    common stock
    Additional
    paid-in
    capital
    Accumulated other comprehensive gain (loss)Accumulated
    deficit
    Total
    stockholders’
    equity
     SharesAmountSharesAmount
    Balance - December 31, 2024146,953,271 $16 19,937,500 $2 $811,998 $45 $(596,641)$215,420 
    Common stock issued upon exercise of stock options623,834 — — — 1,600 — — 1,600 
    Common stock issued upon vesting of restricted stock units358,511 — — — — — — — 
    Common stock issued from direct equity offering, net of fees and issuance costs15,625,000 — — — 46,774 — — 46,774 
    Stock-based compensation— — — — 2,362 — — 2,362 
    Net unrealized loss on marketable securities, net of tax— — — — — (53)— (53)
    Foreign currency translation— — — — — 6 — 6 
    Net loss— — — — — — (19,189)(19,189)
    Balance - March 31, 2025163,560,616 $16 19,937,500 $2 $862,734 $(2)$(615,830)$246,920 
     Class A
    common stock
    Class B
    common stock
    Additional
    paid-in
    capital
    Accumulated other comprehensive loss
    Accumulated
    deficit
    Total stockholders’
    equity
     SharesAmountSharesAmount
    Balance - December 31, 2023121,832,417 $12 19,937,500 $2 $767,239 $— $(495,634)$271,619 
    Common stock issued upon vesting of restricted stock units46,572 — — — — — — — 
    Stock-based compensation— — — — 1,645 — — 1,645 
    Net unrealized loss on marketable securities, net of tax— — — — — (28)— (28)
    Refund of issuance costs— — — — 14 — — 14 
    Foreign currency translation— — — — — (5)— (5)
    Net loss— — — — — — (19,474)(19,474)
    Balance - March 31, 2024121,878,989 $12 19,937,500 $2 $768,898 $(33)$(515,108)$253,771 

    The accompanying notes are an integral part of these Condensed Consolidated Financial Statements.
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    QUANTUM-SI INCORPORATED
    CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
    (in thousands)
    (unaudited)
    Three months ended March 31,
    20252024
    Cash flows from operating activities:
    Net loss$(19,189)$(19,474)
    Adjustments to reconcile net loss to net cash used in operating activities:
    Depreciation and amortization917 1,061 
    Non-cash lease expense631 588 
    Accretion on marketable securities(2,132)(2,119)
    Loss on disposal of fixed assets15 — 
    Write-down of inventory696 591 
    Change in fair value of warrant liabilities(3,401)(319)
    Stock-based compensation2,362 1,645 
    Other— 22 
    Changes in operating assets and liabilities:
    Accounts receivable, net301 126 
    Inventory(1,093)(819)
    Prepaid expenses and other current assets(730)31 
    Accounts payable(15)(633)
    Accrued expenses and other current liabilities(3,624)(3,094)
    Operating lease liabilities(894)(820)
    Other long-term liabilities2 6 
    Net cash used in operating activities(26,154)(23,208)
    Cash flows from investing activities:
    Purchases of property and equipment(1,307)(1,046)
    Internally developed software - capitalized costs— (59)
    Purchases of marketable securities(119,667)(78,823)
     Sales and maturities of marketable securities86,800 22,500 
    Net cash used in investing activities(34,174)(57,428)
    Cash flows from financing activities:
    Proceeds from exercise of stock options1,600 — 
    Proceeds from issuance of common stock from direct equity offering, net of fees and issuance costs46,774 — 
    Deferred offering costs— (70)
    Refund of issuance costs— 14 
    Net cash provided by (used in) financing activities48,374 (56)
    Effect of exchange rate changes on cash and cash equivalents6 (5)
    Net decrease in cash and cash equivalents(11,948)(80,697)
    Cash and cash equivalents at beginning of period49,241 133,860 
    Cash and cash equivalents at end of period$37,293 $53,163 
    Supplemental disclosure of cash flow information:
    Cash paid for income taxes$— $16 
    Supplemental disclosure of non-cash investing and financing activities:
    Property and equipment purchased but not paid$28 $231 
    Deferred offering costs payable$— $75 
    The accompanying notes are an integral part of these Condensed Consolidated Financial Statements.
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    QUANTUM-SI INCORPORATED
    NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
    (Unaudited)
    Note 1. Description of Business and Basis of Presentation
    Background
    Quantum-Si Incorporated (including its subsidiaries, the “Company” or “Quantum-Si”) was incorporated in Delaware on June 10, 2020 as HighCape Capital Acquisition Corp. (“HighCape”). The Company’s legal name became Quantum-Si Incorporated following a business combination on June 10, 2021 between the Company and Q-SI Operations Inc. (formerly Quantum-Si Incorporated) (the “Business Combination”), which was founded in 2013.
    Quantum-Si is a life sciences company focused on proteomics research, with the mission of transforming single-molecule analysis and democratizing its use by providing researchers and clinicians access to the proteome, the set of proteins expressed within a cell. The Company has developed a proprietary universal single-molecule detection platform that it is applying to proteomics to enable Next-Gen Protein SequencingTM (“NGPS”), to sequence proteins in a massively parallel fashion (rather than sequentially, one at a time), which can also be used for the study of nucleic acids. The Company believes that the ability to sequence proteins in a massively parallel fashion and offer a fast analysis time provides NGPS with the potential to unlock significant biological information through improved resolution and unbiased access to the proteome at a speed and scale that is not available today. Traditionally, proteomic workflows to sequence proteins required days or weeks to complete. The Company’s platform includes its Platinum line of NGPS instruments, Platinum Analysis Software, and consumable kits for use with its Platinum line of instruments.
    Liquidity and Capital Resources
    The Company has historically financed its operations primarily with proceeds from the issuance of equity to private investors, as well as with the proceeds received from the closing of the Business Combination. The Company has incurred significant losses and negative cash flows from operations in all periods since inception and had an accumulated deficit of $615.8 million as of March 31, 2025. The Company has incurred significant operating losses, including net losses of $19.2 million and $19.5 million for the three months ended March 31, 2025 and 2024, respectively. As of March 31, 2025, the Company had cash, cash equivalents and investments in marketable securities of $232.6 million. Management believes that the Company’s current cash, cash equivalents and marketable securities, together with revenue from the sales of its products and services, will be sufficient to fund its planned operations for at least the next twelve months from the date of the issuance of the accompanying Condensed Consolidated Financial Statements.
    Until such time as the Company can generate significant revenue from product sales, if ever, it expects to finance its operations through private and public equity offerings, debt financings, and/or potential future collaboration, license and development agreements. However, there can be no assurance that the Company will be able to complete any such transactions on acceptable terms or otherwise, and the Company may be unable to obtain sufficient additional capital when needed. The inability to raise capital as and when needed would have a negative impact on the Company’s financial condition and its ability to pursue its business strategy. The Company will need to generate significant revenue to achieve profitability and it may never do so.
    Global Developments
    Although the U.S. Federal Reserve lowered interest rates slightly in 2024, it is not known whether additional action will be taken to lower interest rates and if this decrease, and any other decreases, will have an impact on inflation. While these rate fluctuations have not had a significant adverse impact on the Company to date, the impact of such rate increases on the overall financial markets and the economy may adversely impact the Company in the future. In addition, the global economy has experienced and is continuing to experience high levels of inflation and global supply chain disruptions. The Company continues to monitor these supply chain, inflation and interest rate factors, as well as the uncertainty resulting from the overall economic environment.
    To date, the Company has not been materially affected by enacted tariffs either by the U.S. government or foreign retaliatory tariffs, however, the Company’s finished goods and/or their components could become materially affected by changing tariffs in the future. If increased tariffs are imposed on the Company’s finished goods and/or components, they may impact the business, financial condition, results of operations and cash flows.
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    Although the Company has not been significantly impacted by geopolitical conflicts such as those in Ukraine or Israel and Gaza, the Company has experienced some constraints in product and material availability and increasing costs required to obtain some materials and supplies as a result of these conflicts on the global economy. To date, the business has not been materially impacted by these conflicts, however, as the conflicts continue or worsen, it may impact the business, financial condition, results of operations and cash flows.
    Basis of Presentation and Principles of Consolidation
    The accompanying Condensed Consolidated Financial Statements include the accounts of the Company and have been prepared in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”) and pursuant to the accounting disclosure rules and regulations of the Securities and Exchange Commission (the “SEC”). All intercompany transactions are eliminated.
    These Condensed Consolidated Financial Statements should be read in conjunction with the audited Consolidated Financial Statements and the notes thereto included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2024. The Condensed Consolidated Balance Sheet as of December 31, 2024 included herein was derived from the audited Consolidated Financial Statements as of that date, but does not include all disclosures, including certain notes required by U.S. GAAP, on an annual reporting basis.
    In the opinion of management, the accompanying Condensed Consolidated Financial Statements reflect all normal recurring adjustments necessary to fairly state the financial position, results of operations, and cash flows for the interim periods. The results for the three months ended March 31, 2025 are not necessarily indicative of the results to be expected for any subsequent quarter, the year ending December 31, 2025, or any other period.
    There have been no material changes to the Company’s significant accounting policies as described in the Company’s Annual Report on Form 10-K for the year ended December 31, 2024.
    Reclassifications
    Certain prior year amounts have been reclassified for consistency with the current year’s presentation.
    Note 2. Summary of Significant Accounting Policies
    For the Company’s Significant Accounting Policies, please refer to its Annual Report on Form 10-K for the fiscal year ended December 31, 2024. Any reference in these notes to applicable guidance is meant to refer to the authoritative GAAP as found in the Accounting Standards Codification and Accounting Standards Update (“ASU”) of the Financial Accounting Standards Board (“FASB”).
    Use of Estimates
    The preparation of the Condensed Consolidated Financial Statements in conformity with U.S. GAAP requires the Company to make estimates and assumptions about future events that affect the amounts recorded in its Condensed Consolidated Financial Statements and accompanying notes. Future events and their effects cannot be determined with certainty. On an ongoing basis, management evaluates these estimates and assumptions. Significant estimates and assumptions include:
    •inventory valuation;
    •assumptions used for leases;
    •valuation of warrant liabilities;
    •valuation allowances with respect to deferred tax assets;
    •assumptions associated with revenue recognition; and
    •assumptions underlying the fair value used in the calculation of the stock-based compensation.
    The Company bases these estimates on historical and anticipated results and trends and on various other assumptions the Company believes are reasonable under the circumstances, including assumptions as to future events. Changes in estimates
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    are recorded in the period in which they become known. Actual results could differ from those estimates, and any such differences may be material to the Condensed Consolidated Financial Statements.
    Recently Issued Accounting Pronouncements
    In November 2024, the FASB issued ASU No. 2024-03, Disaggregation of Income Statement Expenses (“DISE”), which requires additional disclosure of the nature of expenses included in the income statement. The ASU requires disclosures about specific types of expenses included in the expense captions presented on the face of the income statement as well as disclosures about selling expenses. The amendments in this update are effective for annual reporting periods beginning after December 15, 2026 and interim reporting periods beginning after December 15, 2027, with early adoption permitted. The ASU is required to be applied prospectively with the option for retrospective application. The Company is currently evaluating the impact ASU 2024-03 may have on its Consolidated Financial Statements and disclosures.
    In March 2024, the FASB issued ASU No. 2024-02, Codification Improvements - Amendments to Remove References to the Concepts Statements, which contains amendments to the Codification that remove references to various Concepts Statements. The amendments in ASU 2024-02 are not intended to result in significant accounting changes for most entities. The Company adopted ASU 2024-02 effective January 1, 2025. The adoption of ASU 2024-02 did not have a material impact to the Consolidated Financial Statements and disclosures.
    In December 2023, the FASB issued ASU No. 2023-09, Income Taxes (Topic 740): Improvements to Income Tax Disclosures, which expands income tax disclosure requirements to include additional information related to the rate reconciliation of effective tax rates to statutory rates, as well as additional disaggregation of taxes paid in both U.S. and foreign jurisdictions. The amendments in ASU 2023-09 also remove disclosures related to certain unrecognized tax benefits and deferred taxes. The amendments are effective for fiscal years beginning after December 31, 2024, with early adoption permitted. The new standard is expected to apply prospectively, but retrospective application is permitted. The Company will adopt the new standard for the year ended December 31, 2025 and is currently evaluating the impact ASU 2023-09 may have on its Consolidated Financial Statements and disclosures.
    Note 3. Investments in Marketable Securities
    As of March 31, 2025 and December 31, 2024, the Company’s investments in marketable securities were determined to be available-for-sale securities.
    Dividend and interest income from marketable securities related to the Company’s available-for-sale securities for the three months ended March 31, 2025 and 2024 were as follows (in thousands):
    Three months ended March 31,
    20252024
    Dividend income from marketable securities$221 $975 
    Interest income from marketable securities$2,326 $2,599 
    The following is a summary of the Company’s available-for-sale securities recorded within Marketable securities in the Condensed Consolidated Balance Sheets as of March 31, 2025 and December 31, 2024 (in thousands):
    March 31, 2025
    Amortized
    Costs
    Gross
    Realized Net
    Gains
    Gross
    Unrealized Net
    Gains
    Fair
    Value
    Financial Assets:
    Short-term marketable securities:
    U.S. Treasury securities$130,388 $— $4 $130,392 
    Commercial paper64,903 — 13 64,916 
    Total$195,291 $— $17 $195,308 
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    December 31, 2024
    Amortized
    Costs
    Gross
    Realized Net
    Gains
    Gross
    Unrealized Net
    Gains
    Fair
    Value
    Financial Assets:
    Short-term marketable securities:
    U.S. Treasury securities$108,047 $— $63 $108,110 
    Commercial paper52,243 — 9 52,252 
    Total$160,290 $— $72 $160,362 
    The fair values of the Company’s available-for-sale securities included within Marketable securities in the Condensed Consolidated Balance Sheets as of March 31, 2025 and December 31, 2024, by remaining contractual maturity, are as follows (in thousands):
    March 31, 2025
    One Year
    or Less
    Over
    One Year
    Through
    Five Years
    Over
    Five Years
    Total
    Financial Assets:
    Short-term marketable securities:
    U.S. Treasury securities$130,392 $— $— $130,392 
    Commercial paper64,916 — — 64,916 
    Total$195,308 $— $— $195,308 
    December 31, 2024
    One Year
    or Less
    Over
    One Year
    Through
    Five Years
    Over
    Five Years
    Total
    Financial Assets:
    Short-term marketable securities:
    U.S. Treasury securities$108,110 $— $— $108,110 
    Commercial paper52,252 — — 52,252 
    Total$160,362 $— $— $160,362 
    Note 4. Fair Value of Financial Instruments
    Fair value estimates of financial instruments are made at a specific point in time, based on relevant information about financial markets and specific financial instruments. As these estimates are subjective in nature, involving uncertainties and matters of significant judgment, they cannot be determined with precision. Changes in assumptions can significantly affect estimated fair value.
    The Company measures fair value as the price that would be received to sell an asset or paid to transfer a liability (an exit price) in an orderly transaction between market participants at the reporting date. The Company utilizes a three-tier hierarchy, which prioritizes the inputs used in the valuation methodologies in measuring fair value:
    •Level 1: Valuations based on quoted prices in active markets for identical assets or liabilities that an entity has the ability to access.
    •Level 2: Valuations based on quoted prices for similar assets or liabilities, quoted prices for identical assets or liabilities in markets that are not active, or other inputs that are observable or can be corroborated by observable data for substantially the full term of the assets or liabilities.
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    •Level 3: Valuations based on inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.
    The carrying value of cash and cash equivalents, accounts payable and accrued expenses and other current liabilities approximates their fair values due to the short-term or on demand nature of these instruments. As of March 31, 2025 and December 31, 2024, the Company’s investment portfolio included available-for-sale securities which were comprised of money market funds, U.S. treasury bills and commercial paper. The Company has U.S. Treasury bills and commercial papers that are classified as Level 2 due to the fair value for these instruments being determined by utilizing observable inputs in similar assets or identical assets in non-active markets.
    Warrants are recorded as Warrant liabilities in the Condensed Consolidated Balance Sheets. The warrant liabilities are measured at fair value at inception and on a recurring basis, with changes in fair value presented as Change in fair value of warrant liabilities in the Condensed Consolidated Statements of Operations and Comprehensive Loss.
    The Public Warrants and Private Warrants were carried at fair value as of March 31, 2025 and December 31, 2024. The Public Warrants were valued using Level 1 inputs as they are traded in an active market. The Private Warrants were valued using a binomial lattice model. The primary unobservable input utilized in determining the fair value of the Private Warrants was the expected volatility of the Company’s Class A common stock. The expected volatility was based on consideration of the implied volatility from the Company’s own Public Warrant pricing and on the historical volatility observed at guideline public companies. As of March 31, 2025, the assumptions used in preparing the binomial lattice model for valuing the Private Warrants liability include (i) volatility of 201.5%, (ii) risk-free interest rate of 4.0%, (iii) strike price of $11.50, (iv) fair value of Class A common stock of $1.20, and (v) expected life of 1.2 years. As of December 31, 2024, the assumptions used in preparing the binomial lattice model for valuing the Private Warrants liability include (i) volatility of 194.3%, (ii) risk-free interest rate of 4.2%, (iii) strike price of $11.50, (iv) fair value of Class A common stock of $2.70, and (v) expected life of 1.4 years.
    There were no exercises or redemptions of the Public Warrants or Private Warrants during the three months ended March 31, 2025 and 2024.
    The following table summarizes the Company’s assets and liabilities in the Condensed Consolidated Balance Sheets as of March 31, 2025 and December 31, 2024, that are measured at fair value on a recurring basis, by level, within the fair value hierarchy (in thousands):
    March 31, 2025
    Level 1Level 2Level 3Total
    Financial Assets:
    Cash equivalents:
    Money market funds$20,308 $— $— $20,308 
    Commercial paper11,381 — — 11,381 
    Marketable securities:
    U.S. Treasury securities— 130,392 — 130,392 
    Commercial paper— 64,916 — 64,916 
    Total assets at fair value on a recurring basis$31,689 $195,308 $— $226,997 
    Liabilities:
    Public Warrants$1,533 $— $— $1,533 
    Private Warrants— — 61 61 
    Total liabilities at fair value on a recurring basis$1,533 $— $61 $1,594 
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    December 31, 2024
    Level 1Level 2Level 3Total
    Financial Assets:
    Cash equivalents:
    Money market funds$20,340 $— $— $20,340 
    U.S. Treasury securities16,919 — — 16,919 
    Marketable securities:
    U.S. Treasury securities— 108,110 — 108,110 
    Commercial paper— 52,252 — 52,252 
    Total assets at fair value on a recurring basis$37,259 $160,362 $— $197,621 
    Liabilities:
    Public Warrants$4,792 $— $— $4,792 
    Private Warrants— — 203 203 
    Total liabilities at fair value on a recurring basis$4,792 $— $203 $4,995 
    Note 5. Inventory
    Inventory consists of the following as of March 31, 2025 and December 31, 2024 (in thousands):
    March 31,
    2025
    December 31,
    2024
    Raw materials$1,528 $1,290 
    Work in progress2,097 2,212 
    Finished goods798 565 
    Total inventory$4,423 $4,067 
    Charges recorded for inventory write-downs included in Research and development expenses in the Condensed Consolidated Statements of Operations and Comprehensive Loss for the three months ended March 31, 2025 and 2024 were $0.5 million and $0.6 million, respectively. Charges recorded for inventory write-downs included in Cost of revenue in the Condensed Consolidated Statements of Operations and Comprehensive Loss were $0.2 million for the three months ended March 31, 2025 and immaterial for the three months ended March 31, 2024.
    Note 6. Property and Equipment, Net
    Property and equipment, net, consists of the following as of March 31, 2025 and December 31, 2024 (in thousands):
    March 31,
    2025
    December 31,
    2024
    Laboratory and production equipment$13,928 $13,412 
    Computer equipment1,692 1,724 
    Purchased software57 57 
    Furniture and fixtures318 321 
    Leasehold improvements7,226 7,226 
    Construction in process5,687 4,960 
    Subtotal28,908 27,700 
    Less: Accumulated depreciation and amortization
    (12,729)(11,707)
    Property and equipment, net$16,179 $15,993 
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    Depreciation and amortization expense is included within Cost of revenue, Research and development and Selling, general and administrative expenses in the Condensed Consolidated Statements of Operations and Comprehensive Loss. Depreciation and amortization expense was $0.9 million and $1.1 million for the three months ended March 31, 2025 and 2024, respectively. No impairments of property and equipment were recorded for both the three months ended March 31, 2025 or 2024.
    Note 7. Leases
    Lease-related costs for the three months ended March 31, 2025 and 2024 are as follows (in thousands):
    Three months ended March 31,
    20252024
    Operating lease cost$864 $864 
    Variable lease cost384 436 
    Total lease cost$1,248 $1,300 
    Future minimum lease payments under non-cancellable leases as of March 31, 2025 are as follows (dollars in thousands):
    Remaining Lease Payments
    Remainder of 2025$3,400 
    20264,585 
    20274,549 
    20282,975 
    20292,806 
    Thereafter7,247 
    Total remaining undiscounted lease payments$25,562 
    Less: Imputed interest(4,404)
    Less: Lease incentives(1)
    (9,104)
    Total lease liabilities12,054 
    Less: current portion(1,936)
    Long-term operating lease liabilities$10,118 
    Weighted-average remaining lease term (in years)5.4
    Weighted-average discount rate7.9 %
    (1)Includes lease incentives that are estimated to be realized in 2026 and 2027 for the costs of leasehold improvements.
    The following table provides certain cash flow and supplemental cash flow information related to the Company’s right-of-use assets and lease liabilities for the three months ended March 31, 2025 and 2024 (in thousands):
    Three months ended March 31,
    20252024
    Operating cash paid to settle operating lease liabilities$1,127 $1,097 
    As of both March 31, 2025 and December 31, 2024, the Company has incurred and recognized total leasehold improvements of approximately $1.2 million related to reimbursable construction costs included in construction in progress within Property and equipment, net, in the Condensed Consolidated Balance Sheets.
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    Note 8. Accrued Expenses and Other Current Liabilities
    As of March 31, 2025 and December 31, 2024, Accrued expenses and other current liabilities consisted of the following (in thousands):
    March 31,
    2025
    December 31,
    2024
    Legal fees$1,717 $2,166 
    Sales tax payable1,338 1,339 
    Restructuring costs325 679 
    Deferred revenue155 189 
    Royalties133 150 
    Other172 325 
    Total accrued expenses and other current liabilities$3,840 $4,848 
    Note 9. Equity Transactions
    Registered Direct Offering
    On January 3, 2025, the Company entered into a securities purchase agreement with certain institutional investors pursuant to which the Company agreed to issue and sell, in a registered direct offering (the “Registered Direct Offering”) an aggregate of 15,625,000 shares of the Company’s Class A common stock at a price of $3.20 per share. The gross proceeds to the Company from the Registered Direct Offering were $50.0 million. After deducting estimated placement agents’ fees and other offering expenses payable by the Company, net proceeds recorded during the three months ended March 31, 2025 were approximately $46.8 million.
    Preferred Stock
    As of March 31, 2025 and December 31, 2024, the Company had authorized 1,000,000 shares of preferred stock at $0.0001 par value per share. There were no preferred shares outstanding for both periods.
    Preferred stock may be issued from time to time in one or more series. Any shares of preferred stock which may be redeemed, purchased or acquired by the Company may be reissued except as otherwise provided by law.
    Note 10. Stock-based Compensation
    Equity Incentive Plan
    The Quantum-Si Incorporated 2021 Equity Incentive Plan (the “2021 Plan”) provides for grants of stock options, stock appreciation rights, restricted stock, restricted stock units, and other stock or cash-based awards. Directors, officers and other employees of the Company and its subsidiaries, as well as others performing consulting or advisory services for the Company, are eligible for grants under the 2021 Plan. As of March 31, 2025, there were 13,952,174 shares available for future grant under the 2021 Plan.
    Inducement Equity Incentive Plan
    On May 8, 2023, the Company adopted the 2023 Inducement Equity Incentive Plan (the “2023 Inducement Plan”) to reserve 3,000,000 shares of its Class A common stock to be used exclusively for grants of awards to individuals that were not previously employees or directors of the Company as a material inducement to such individuals’ entry into employment with the Company within the meaning of Rule 5635(c)(4) of the Nasdaq Listing Rules. On August 23, 2024, the Company amended the 2023 Inducement Plan to reserve an additional 3,000,000 shares of its Class A common stock under the 2023 Inducement Plan. The terms and conditions of the 2023 Inducement Plan, as amended, are substantially similar to those of the 2021 Plan. As of March 31, 2025, there were 1,603,795 shares available for future issuance under the 2023 Inducement Plan
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    Stock Options
    The Company granted an aggregate of 32,000 stock option awards to participants during the three months ended March 31, 2025, with vesting subject to the participant’s continued employment with or continued service provided to the Company through the applicable vesting dates. During the three months ended March 31, 2024, the Company did not grant any stock options to participants.
    The Company recorded $1.5 million and $1.3 million for stock-based compensation related to stock options for the three months ended March 31, 2025 and 2024, respectively.
    The fair value of each stock option award granted during the three months ended March 31, 2025 was estimated as of the grant date using a Black-Scholes model with the following assumptions:
    Three months ended March 31, 2025
    Expected term (in years)
    4.6
    Risk-free interest rate
    4.4%
    Expected volatility
    114.2%
    Expected dividend yield—
    Weighted average grant date fair value per share$1.88
    A summary of the stock option activity for the three months ended March 31, 2025 is presented in the table below:
    Number of
    Options
    Weighted Average
    Exercise Price
    (per share)
    Weighted Average
    Remaining
    Contractual Term
    (in years)
    Aggregate
    Intrinsic Value
    (in thousands)
    Outstanding at December 31, 202420,803,142$2.61 7.8$11,507 
    Granted32,0002.35 
    Exercised(623,834)2.57 
    Forfeited(599,063)4.76 
    Outstanding at March 31, 202519,612,245$2.55 7.7$172 
    Options exercisable at March 31, 20258,467,713$3.15 6.7$10 
    Vested and expected to vest at March 31, 202516,987,541$2.62 7.6$134 
    As of March 31, 2025, total unrecognized stock-based compensation related to stock options was $9.9 million, which is expected to be recognized over a remaining weighted average vesting period of 2.2 years.
    Performance Stock Options
    In November 2022 and May 2023, the Company granted 2,780,000 and 1,000,000 performance-based stock option awards to its Chief Executive Officer and Chief Financial Officer, respectively. The vesting of these awards are subject to continued service to the Company and certain market conditions. The market conditions require the Company’s Class A common stock trade above specified levels for certain periods of time. The fair values of the awards were estimated at the grant date using the Monte Carlo simulation model.
    On March 15, 2024, the market conditions that trigger the vesting of these performance-based stock option awards were modified. The modified market conditions require the Company’s Class A common stock to trade above specified levels for certain defined periods of time that are different from the original awards. The Company accounted for the modifications as modifications of market conditions. The total incremental stock-based compensation expense to be recognized for these awards within Selling, general and administrative operating expenses in the Condensed Consolidated Statements of Operations and Comprehensive Loss is approximately $2.4 million. Incremental stock-based compensation
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    expense for the three months ended March 31, 2025 was $0.2 million. Incremental stock-based compensation expense for the three months ended March 31, 2024 was immaterial.
    Restricted Stock Units
    The Company recorded $0.8 million and $0.3 million of stock-based compensation expense related to restricted stock unit (“RSU”) awards for the three months ended March 31, 2025 and 2024, respectively.
    A summary of the RSU activity for the three months ended March 31, 2025 is presented in the table below:
    Number
    of Shares
    Underlying
    RSUs
    Weighted
    Average
    Grant-Date
    Fair Value
    Outstanding non-vested RSUs at December 31, 20247,179,009$1.39 
    Granted8,104,4731.21 
    Vested(358,511)1.86 
    Forfeited
    (72,292)1.52 
    Outstanding non-vested RSUs at March 31, 202514,852,679$1.28 
    As of March 31, 2025, total unrecognized stock-based compensation related to restricted stock was $18.2 million, which is expected to be recognized over the remaining weighted average vesting period of 3.6 years.
    Stock-based compensation is allocated to Research and development and Selling, general and administrative operating expenses in the Condensed Consolidated Statements of Operations and Comprehensive Loss. Stock-based compensation expense for the years ended March 31, 2025 and 2024 is as follows (in thousands):
    Three months ended March 31,
    20252024
    Research and development$596 $490 
    Selling, general and administrative1,766 1,155 
    Total stock-based compensation
    $2,362 $1,645 
    No related tax benefits of the stock-based compensation expense have been recognized and no related tax benefits have been realized from the exercise of stock options due to the Company’s net operating loss carryforwards.
    Note 11. Warrant Liabilities
    Public Warrants
    As of March 31, 2025 and December 31, 2024, there were an aggregate of 3,833,319 outstanding Public Warrants, which entitle the holder to acquire Class A common stock. Each whole warrant entitles the registered holder to purchase one share of Class A common stock at an exercise price of $11.50 per share, subject to adjustment as discussed below, beginning on September 9, 2021. The warrants will expire on June 10, 2026 or earlier upon redemption or liquidation.
    Redemptions
    At any time while the warrants are exercisable, the Company may redeem not less than all of the outstanding Public Warrants:
    • in whole and not in part;
    •at a price of $0.01 per warrant;
    •upon not less than 30 days’ prior written notice of redemption (the “30-day redemption period”) to each warrant holder; and
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    •if, and only if, the closing price of the Company’s Class A common stock equals or exceeds $18.00 per share (as adjusted for stock splits, stock capitalizations, reorganizations, recapitalizations and the like) for any 20 trading days within a 30-trading day period ending three business days before the Company sends the notice of redemption to the warrant holders.
    If the foregoing conditions are satisfied and the Company issues a notice of redemption of the Public Warrants at $0.01 per warrant, each holder of Public Warrants will be entitled to exercise their Public Warrants held prior to the scheduled redemption date.
    If the Company calls the Public Warrants for redemption for $0.01 as described above, the Board may elect to require any holder that wishes to exercise his, her or its Public Warrants to do so on a “cashless basis.” If the Board makes such election, all holders of Public Warrants would pay the exercise price by surrendering their warrants for that number of shares of Class A common stock equal to the quotient obtained by dividing (x) the product of the number of shares of Class A common stock underlying the warrants, multiplied by the excess of the “fair market value” over the exercise price of the warrants by (y) the “fair market value”. For purposes of the redemption provisions of the warrants, the “fair market value” means the average last reported sale price of the Class A common stock for the 10 trading days ending on the third trading day prior to the date on which the notice of redemption is sent to the holders of warrants.
    The Public Warrants do not meet the criteria to be classified in stockholders’ equity as the exercise of the Public Warrants may be settled in cash upon the occurrence of a tender offer or exchange offer in which the maker of the tender offer or exchange offer, upon completion of the tender offer or exchange offer, beneficially owns more than 50% of the outstanding shares of the Company’s Class A common stock, even if it would not result in a change of control of the Company. This provision precludes the Public Warrants from being classified in equity and thus they are classified as long-term liabilities in the Condensed Consolidated Balance Sheets.
    Private Warrants
    As of March 31, 2025 and December 31, 2024, there were 135,000 Private Warrants outstanding. The Private Warrants are identical to the Public Warrants, except that so long as they are held by HighCape Capital Acquisition LLC or any of its permitted transferees, (i) the Private Warrants and the shares of Class A common stock issuable upon the exercise of the Private Warrants were not transferable, assignable or saleable until 30 days after the completion of the Business Combination, (ii) the Private Warrants will be exercisable for cash or on a cashless basis, at the holder’s option, and (iii) the Private Warrants are not subject to the Company’s redemption option at the price of $0.01 per warrant. The Private Warrants are subject to the Company’s redemption option at the price of $0.01 per warrant, provided that the other conditions of such redemption are met, as described above. If the Private Warrants are held by a holder other than HighCape Capital Acquisition LLC or any of its permitted transferees, the Private Warrants will be redeemable by the Company in all redemption scenarios applicable to the Public Warrants and exercisable by such holders on the same basis as the Public Warrants.
    The Private Warrants do not meet the criteria to be classified in stockholders’ equity as the terms of the warrants provide for potential changes to the settlement amounts depending upon the characteristics of the warrant holder, and, because the holder of a warrant is not an input into the pricing of a fixed-for-fixed option on equity shares. This provision precludes the Private Warrants from being classified in equity and thus they are classified as long-term liabilities in the Condensed Consolidated Balance Sheets.
    As of March 31, 2025 and December 31, 2024, the combined fair value of warrant liabilities was $1.6 million and $5.0 million, respectively. The Company recognized gains of $3.4 million and $0.3 million as a Change in fair value of warrant liabilities in the Condensed Consolidated Statements of Operations and Comprehensive Loss for the three months ended March 31, 2025 and 2024, respectively. There were no exercises or redemptions of the Public Warrants or Private Warrants during the three months ended March 31, 2025 or 2024.
    For further details regarding the warrant liabilities, please refer to Note 4. Fair Value of Financial Instruments.
    Note 12. Net Loss Per Share
    The Company presents both basic earnings per share (“EPS”) and diluted EPS. Basic and diluted net loss per share was the same for each period presented as the inclusion of all common share equivalents would have been anti-dilutive.
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    The following table presents the calculations for the three months ended March 31, 2025 and 2024 of basic and diluted net loss per share for the Company’s common stock (in thousands, except per share amounts):
    Three months ended March 31,
    20252024
    Numerator
    Net loss$(19,189)$(19,474)
    Numerator for basic and diluted EPS - loss attributable to common stockholders$(19,189)$(19,474)
    Denominator
    Common stock182,303141,773
    Denominator for basic and diluted EPS - weighted-average common stock182,303141,773
    Basic and diluted net loss per share$(0.11)$(0.14)
    Net loss per share attributable to Class A and Class B common stockholders was the same on a basic and diluted basis, as the inclusion of all potential common equivalent shares outstanding would have been anti-dilutive. The following potential dilutive shares were excluded from the calculation of diluted net loss per share because their effect would be anti-dilutive for the three months ended March 31, 2025 and 2024 (in thousands):
    Three months ended March 31,
    20252024
    Outstanding options to purchase common stock19,612,245 22,101,807 
    Outstanding restricted stock units14,852,679 6,152,344 
    Outstanding warrants3,968,319 3,968,319 
    38,433,243 32,222,470 
    Note 13. Restructuring
    The Company committed to organizational restructurings during the fourth quarter of 2024, designed to decrease its costs and create a more streamlined organization to support its business. Restructuring liabilities were $0.3 million and $0.7 million as of March 31, 2025 and December 31, 2024, respectively. These liabilities are included in Accrued expenses and other current liabilities in the Condensed Consolidated Balance Sheets.
    The Company’s restructuring costs, primarily for cash severance and other severance costs, are allocated to the following operating expense categories as follows (in thousands):
    Research and developmentSelling, general and administrativeTotal
    Balance as of December 31, 2024$513 $166 $679 
    Cash payments and other adjustments(1)
    (212)(142)(354)
    Balance as of March 31, 2025$301 $24 $325 
    Current liabilities$325 
    Long-term liabilities— 
    Total liabilities as of March 31, 2025$325 
    (1) Cash payments and other adjustments include charges related to health care coverage for a specified period of time after separation.
    The Company’s restructuring activities were complete as of December 31, 2024. The Company does not expect to incur additional charges associated with these activities.
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    Note 14. Income Taxes
    Income taxes for the three months ended March 31, 2025 and 2024 were recorded at the Company’s estimated annual effective income tax rate, subject to adjustments for discrete events, if they occur. The Company’s estimated annual effective tax rate was (0.06)% and 0.00% for the three months ended March 31, 2025 and 2024, respectively. The primary reconciling items between the federal statutory rate of 21.0% and the Company’s overall effective tax rates for these periods were related to the effects of deferred state income taxes, stock-based compensation, changes in the fair value of warrant liabilities, research and development credits and the valuation allowance recorded against the full amount of the Company’s net deferred tax assets. In addition to the previously mentioned reconciling items, the reconciling items for the three months ended March 31, 2025 also included foreign taxes.
    A valuation allowance is required when it is more likely than not that some portion or all of the Company’s deferred tax assets will not be realized. The realization of deferred tax assets depends on the generation of sufficient future taxable income during the period in which the Company’s related temporary differences become deductible. Management believes that based on the earnings history of the Company, it is more likely than not that the benefits of these assets will not be realized, and therefore, a full valuation allowance has been recorded against the Company’s net deferred tax assets as of March 31, 2025 and December 31, 2024.
    Note 15. Segment Information
    Quantum-Si is a life sciences company focused on proteomics research, with the mission of transforming single-molecule analysis and democratizing its use by providing researchers and clinicians access to the proteome, the set of proteins expressed within a cell. Our platform includes our Platinum NGPS instrument, Platinum Analysis Software, and consumable kits for use with our Platinum line of instruments.
    The Company’s Chief Operating Decision Maker (the “CODM”), its Chief Executive Officer, reviews financial information presented on a consolidated basis for purposes of assessing financial performance, making operating decisions and allocating resources. Accordingly, the Company has determined that it operates as a single reportable segment. The CODM utilizes the Company’s long-range plan, which includes product development roadmaps and long-range financial models, as a key input to resource allocation. The CODM makes decisions on resource allocation, assesses the performance of the business, and monitors budget versus actual results on a consolidated basis using loss from operations as reported on the Condensed Consolidated Statements of Operations and Comprehensive Loss. Net loss and the change in cash and cash equivalents and marketable securities are also measures that are considered in monitoring budget versus actual results.
    Significant expenses within loss from operations, as well as within net loss, include research and development, and selling, general and administrative expenses, which are each separately presented on the Company’s Condensed Consolidated Statements of Operations and Comprehensive Loss.
    The Company’s revenue is derived from sales of products and services. Product revenue is primarily generated from the sales of instruments and consumables used in protein sequencing and analysis. Service revenue is primarily generated from service maintenance contracts including access to analysis software and advanced training for instrument use.
    Total revenue generated from domestic and international sales for the three months ended March 31, 2025 and 2024 is as follows (in thousands):
    Three months ended March 31,
    20252024
    Domestic$123 $237 
    International719 220 
    Total revenue$842 $457 
    Note 16. Related Party Transactions
    The Company was a party to the Amended and Restated Technology Services Agreement (the “ARTSA”), most recently amended on November 11, 2020, by and among 4Catalyzer Corporation (“4C”), the Company and other participant companies controlled by Dr. Jonathan Rothberg, the Chairman of the Company’s Board of Directors. The Company entered into a First Addendum to the ARTSA on February 17, 2021 pursuant to which the Company agreed to terminate its participation under the ARTSA no later than immediately prior to the effective time of the Business Combination, resulting
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    in the termination of the Company’s participation under the ARTSA on June 10, 2021. In connection with the termination of the Company’s participation under the ARTSA, the Company terminated its existing arm’s length lease agreement with 4C and negotiated an arm’s length lease agreement. Under the ARTSA, the Company and the other participant companies had agreed to share certain non-core technologies, which means any technologies, information or equipment owned or otherwise controlled by the participant company that are not specifically related to the core business area of the participant and subject to certain restrictions on use. The ARTSA also provided for 4C to perform certain services for the Company and each other participant company such as monthly administrative, management and technical consulting services to the Company which were pre-funded approximately once per quarter.
    The Company incurred expenses paid to 4C of $0.1 million for both the three months ended March 31, 2025 and 2024. These expenses included amounts for month-to-month sublease arrangements for office and laboratory spaces from 4C and certain administrative expenses. These amounts are included in Selling, general and administrative expenses in the Condensed Consolidated Statements of Operations and Comprehensive Loss. As of both March 31, 2025 and December 31, 2024 amounts due to 4C were immaterial.
    The ARTSA also provided for the participant companies to provide other services to each other. As of both March 31, 2025 and December 31, 2024, there were no amounts payable to or from the Company related to these services.
    Effective November 1, 2022, the Company entered into an Advisory Agreement with Dr. Rothberg (the “Advisory Agreement”), pursuant to which Dr. Rothberg previously served as Chairman of the Board, advises the Chief Executive Officer and the Board on strategic matters, and provides consulting, business development and similar services on matters relating to the Company’s current, future and potential scientific and strategic initiatives and such other consulting services reasonably requested from time to time. Pursuant to the Advisory Agreement, as compensation for the services provided, in March 2023, the Company granted Dr. Rothberg an option to purchase 250,000 shares of Class A common stock pursuant to the 2021 Plan. In connection with the Advisory Agreement, Dr. Rothberg’s title was changed from Executive Chairman to Chairman of the Board. Subsequently, in May 2024, with Charles Kummeth’s appointment as Chairman of the Board, Dr. Rothberg’s title was changed from Chairman of the Board to Director.
    Note 17. Commitments and Contingencies
    Commitments
    Licenses related to certain intellectual property:
    The Company licenses certain intellectual property, some of which may be utilized in its current or future product offerings. To preserve the right to use such intellectual property, the Company is required to make annual minimum fixed payments totaling approximately $0.2 million as well as royalties based on net sales if the royalties exceed annual minimum fixed payments. As of March 31, 2025 and December 31, 2024, the Company had accrued royalties of approximately $0.1 million and $0.2 million included in Accrued expenses and other current liabilities in the Condensed Consolidated Balance Sheets.
    Other commitments:
    The Company sponsors a 401(k) defined contribution plan covering all eligible U.S. employees (the “401(k) Plan”). Contributions to the 401(k) Plan are discretionary. The Company did not make any matching contributions to the 401(k) Plan for the three months ended March 31, 2025 and 2024.
    Contingencies
    The Company is subject to claims in the ordinary course of business. Except as discussed below, the Company is not currently a party to any pending or threatened litigation, the outcome of which would be expected to have a material adverse effect on its financial condition, results of operations, or cash flows. The Company discloses contingent liabilities even if the liability is not probable or estimable, or both, if there is a reasonable possibility that a material loss may have been incurred.
    On May 16, 2024, a punitive class action lawsuit was filed in the Delaware Court of Chancery, styled Farzad v. HighCape Capital, et al. (the “Delaware Stockholder Litigation”). The Delaware Stockholder Litigation asserts breach of fiduciary duty claims against the former officers and directors of HighCape, including Kevin Rakin, Matt Zuga, David Colpman,
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    Robert Taub and Antony Loebel, HighCape Capital Acquisition LLC and HighCape Capital L.P., aiding and abetting breach of fiduciary duty claims against Foresite Capital Management, LLC and Dr. Rothberg, and unjust enrichment claims against all defendants related to the Business Combination. The Delaware Stockholder Litigation complaint alleges that the transactions contemplated by the Business Combination were a product of an unfair process which was allegedly impacted by conflicts of interest, resulting in mispricing of the Business Combination. The complaint seeks, among other things, unspecified damages and attorneys’ fees and costs. As of May 15, 2025, the parties were working through various motions associated with the case and no trial date has been set. Quantum-Si, as part of the Business Combination, had previously agreed to indemnify certain of the defendants related to actions such as the Delaware Stockholder Litigation to the extent allowable by law. There is no assurance that defendants will be successful in the defense of the litigation or that insurance will be available or adequate to fund any potential settlement or judgment or the litigation costs of the action. Further, since the Quantum-Si has indemnified certain of the defendants to the extent allowable by law, there is no guarantee that insurance available to Quantum-Si will be available or adequate to fund any potential settlement or judgment or related costs associated with the indemnified parties. At the time of this filing, the outcome of this matter is not estimable or probable.
    In April 2023, the Company informed the contract manufacturer that had manufactured the Platinum and another development product, Carbon™, that it intended to wind down the relationship and transition to a different contract manufacturer. In October 2023, the former contract manufacturer filed a complaint against the Company in the State of Texas alleging breach of contract and made claims for economic damage and attorney costs. In January 2024, the suit was withdrawn and refiled in the State of Minnesota alleging similar claims. The Company denied all liability and countersued alleging claims of negligence. In February 2025, the court ordered mandatory non-binding settlement conference to take place on June 27, 2025. Although it is not possible to determine the potential financial exposure associated with the alleged claim at this time given its early stage, the Company believes it has a meritorious defense and intends to vigorously defend against all claims asserted in the complaint. At the time of this filing, the outcome of this matter is not estimable or probable.
    In December 2021, the Company signed a 10-year lease for approximately 67,000 square feet of space in New Haven, Connecticut. The lease commenced on January 8, 2022 with rent payments beginning on July 7, 2022. Under the lease, the landlord contractually agreed to reimburse the Company for up to $9.1 million in improvements to the space, to be used for such improvements as the Company deems “necessary or desirable”. On September 13, 2022, the Company filed a lawsuit against the landlord, alleging that the landlord has: (i) refused to reimburse the Company for costs related to improvements already incurred and submitted, (ii) delayed the Company’s completion of improvements, in order to avoid reimbursing the costs of those improvements, and (iii) improperly rejected the Company’s proposed improvement plans. The Company accounted for these lease incentives as an offset to the lease liability recorded at the inception of the lease. In September 2024, the Company determined there was a change in the estimated timing of receipt of reimbursements for the improvements. This resulted in an increase of the carrying value of the right-of-use asset and the corresponding lease liabilities of $1.0 million. Although the Company believes it is contractually entitled to the $9.1 million of lease incentives, based on the current status of the litigation, the Company cannot determine the likely outcome or estimate the impact on such carrying values.
    The Company enters into agreements that contain indemnification provisions with other parties in the ordinary course of business, including business partners, investors, contractors, and the Company’s officers, directors and certain employees. The Company has agreed to indemnify and defend the indemnified party claims and related losses suffered or incurred by the indemnified party from actual or threatened third-party claims because of the Company’s activities or non-compliance with certain representations and warranties made by the Company. It is not possible to determine the maximum potential loss under these indemnification provisions due to the Company’s limited history of prior indemnification claims and the unique facts and circumstances involved in any particular case. To date, losses recorded in the Condensed Consolidated Statements of Operations and Comprehensive Loss in connection with the indemnification provisions have not been material.

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    Item 2.    Management’s Discussion and Analysis of Financial Condition and Results of Operations
    The following discussion and analysis provides information which management believes is relevant to an assessment and understanding of our condensed consolidated results of operations and financial condition. The discussion should be read in conjunction with (i) the unaudited Condensed Consolidated Financial Statements and notes thereto contained in this Quarterly Report on Form 10-Q, (ii) the Consolidated Financial Statements and notes thereto for the year ended December 31, 2024 contained in our Annual Report on Form 10-K for the year ended December 31, 2024, filed with the Securities and Exchange Commission (the “SEC”) on March 3, 2025, and (iii) our other public reports filed with the SEC. This discussion contains forward looking statements and involves numerous risks and uncertainties, including, but not limited to, those described in the “Risk Factors” section of our Annual Report on Form 10-K for the year ended December 31, 2024 and this Quarterly Report on Form 10-Q. Actual results may differ materially from those contained in any forward-looking statements. Unless the context otherwise requires, references to “we”, “us”, “our”, the “Company” or “Quantum-Si” are intended to mean the business and operations of Quantum-Si Incorporated and its consolidated subsidiaries. The unaudited Condensed Consolidated Financial Statements for the three months ended March 31, 2025 and 2024 present the financial position and results of operations of Quantum-Si Incorporated and its consolidated subsidiaries.
    Overview
    We are a life sciences company focused on proteomics research, with the mission of transforming single-molecule analysis and democratizing its use by providing researchers and clinicians access to the proteome, the set of proteins expressed within a cell. We have developed a proprietary universal single-molecule detection platform that we are applying to proteomics to enable Next-Gen Protein SequencingTM (“NGPS”), to sequence proteins in a massively parallel fashion (rather than sequentially, one at a time), which can also be used for the study of nucleic acids. We believe that the ability to sequence proteins in a massively parallel fashion and offer a fast analysis time provides NGPS with the potential to unlock significant biological information through improved resolution and unbiased access to the proteome at a speed and scale that is not available today. Traditionally, proteomic workflows to sequence proteins required days or weeks to complete. Our platform includes our Platinum NGPS instrument, Platinum Analysis Software, and consumable kits for use with our Platinum line of instruments. In 2021, we introduced our Platinum early access program to sites with participation from leading academic centers and key industry partners. The early access program introduced the Platinum single-molecule sequencing system to key opinion leaders across the globe for both expansion and development of applications and workflows. We began a controlled launch of the Platinum instrument and started to take orders in December 2022, and subsequently began a controlled commercial launch of Platinum in January 2023, and then moved to a full commercial launch of Platinum beginning the second quarter of 2024. In January 2025, we announced the launch of our Platinum Pro benchtop sequencer. First shipments of Platinum Pro occurred in March 2025.
    Going forward, we intend to follow a systematic, phased approach to continue to successfully launch updates and enhancements to our platform which can include improvements to our hardware, software and chemistry that works together to produce the overall platform.
    We believe that our platform offers a differentiated solution in a rapidly evolving proteomics tools market. Within our initial focus market of proteomics, our platform is designed to provide users a seamless opportunity to gain key insights into the immediate state of biological pathways and cell state. Our platform aims to address many of the key challenges and bottlenecks with legacy proteomic solutions, such as mass spectrometry (“MS”), which include high instrument costs both in terms of acquisition and ownership, and complexity with data analysis, which together limit broad adoption. We believe our platform, which is designed to streamline sequencing and data analysis at a lower instrument cost and with greater automation than legacy proteomic solutions, could allow our product to have wide utility across the study of the proteome. For example, our platform could be used for biomarker discovery and disease detection, pathway analysis, immune response, vaccine development, quality assurance and quality control, among other applications.
    Restructuring
    In November 2024, we announced that we committed to an organizational restructuring program designed to streamline and focus our overall corporate resources, as well as align required resources to focus on future product development objectives, including our recently announced Proteus™ platform. As a result, we terminated approximately 23% of our 187 employee workforce. In connection with the restructuring, we recognized one-time cash charges related to severance and other benefits of approximately $2.3 million in the fourth quarter of 2024. We may also incur additional costs not currently contemplated due to events that may occur as a result of, or that are associated with, the restructuring. Our restructuring
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    activities were complete as of December 31, 2024 and we do not expect to incur additional charges associated with these activities. For further information regarding our restructuring activities, please refer to Note 13. Restructuring.
    Equity Transaction
    On January 3, 2025, we entered into a securities purchase agreement with certain institutional investors pursuant to which we agreed to issue and sell, in a registered direct offering (the “Registered Direct Offering”) an aggregate of 15,625,000 shares of our Class A common stock at a price of $3.20 per share. The gross proceeds from the Registered Direct Offering were $50.0 million. After deducting estimated placement agents’ fees and other offering expenses payable by the Company, net proceeds recorded during the three months ended March 31, 2025 were approximately $46.8 million.
    For further information regarding our equity transaction, please refer to the Liquidity Outlook section below.
    Results of Operations for the Three Months Ended March 31, 2025 as Compared to the Three Months Ended March 31, 2024
    The following table presents the Condensed Consolidated Statements of Operations and Comprehensive Loss for the three months ended March 31, 2025 and 2024 (dollars in thousands):
    Three months ended March 31,
    20252024$ Change% Change
    Revenue:
    Product$808 $428 $380 88.8 %
    Service34 29 5 17.2 %
    Total revenue842 457 385 84.2 %
    Cost of revenue
    Product337 170 167 98.2 %
    Service19 18 1 5.6 %
    Total cost of revenue356 188 168 89.4 %
    Gross profit486 269 217 80.7 %
    Operating expenses:
    Research and development13,717 12,101 1,616 13.4 %
    Selling, general and administrative11,881 11,528 353 3.1 %
    Total operating expenses25,598 23,629 1,969 8.3 %
    Loss from operations(25,112)(23,360)(1,752)7.5 %
    Dividend and interest income2,547 3,574 (1,027)(28.7)%
    Change in fair value of warrant liabilities3,401 319 3,082 966.1 %
    Other expense, net(14)(7)(7)100.0 %
    Loss before provision for income taxes(19,178)(19,474)296 (1.5)%
    Provision for income taxes(11)— (11)
    nm(1)
    Net loss$(19,189)$(19,474)$285 (1.5)%
    (1) “nm” indicates amount is not meaningful.
    Revenue, Cost of Revenue and Gross Profit
    Revenue is derived from sales of products and services. Product revenue is generated from the following sources: (i) sales of our Platinum line of instruments, (ii) consumables kits, including library preparation kits, sequencing kit (which includes sequencing reagents and semiconductor chips), and other related reagent kits, and (iii) freight revenue, which is recognized
    25

    Table of Contents
    upon shipment. Service revenue is generated from service maintenance contracts including Platinum Analysis Software access, and advanced training for instrument use.
    Cost of revenue primarily consists of product and service costs including material costs, personnel costs and benefits, inbound and outbound freight, packaging, warranty replacement costs, royalty costs, facilities costs, depreciation and amortization expense, and inventory write-offs.
    Revenue, Cost of revenue and Gross profit for the three months ended March 31, 2025 and 2024 are as follows (dollars in thousands):
    Three months ended March 31,
    20252024$ Change% Change
    Revenue:
    Product$808 $428 $380 88.8 %
    Service34 29 5 17.2 %
    Total revenue842 457 385 84.2 %
    Cost of revenue
    Product337 170 167 98.2 %
    Service19 18 1 5.6 %
    Total cost of revenue356 188 168 89.4 %
    Gross profit$486 $269 $217 80.7 %
    Gross profit margin57.7 %58.9 %
    Total revenue for the sale of Platinum line of instruments, related reagent kits and service maintenance contracts increased $0.4 million, or 84.2%, for the three months ended March 31, 2025, as compared to the same period in 2024. The increase in revenue was due to higher sales volumes of instruments and consumables as we continue to improve our commercial sales execution.
    Total cost of revenue increased $0.2 million, or 89.4%, for the three months ended March 31, 2025, as compared to the same period in 2024. The increase in cost of revenue is in line with the increase in year-over-year revenue.
    Gross profit increased $0.2 million, or 80.7%, for the three months ended March 31, 2025, as compared to the same period in 2024.

    Gross profit margin was 57.7% for the three months ended March 31, 2025, as compared to 58.9% for the same period in 2024. This change in margin was primarily based on the mix of products sold during each period and includes approximately a 7% and 10% benefit for the three months ended March 31, 2025 and 2024, respectively, for inventory utilized that was carried at low or no value that predates the commercial launch of our Platinum line of instruments. Our gross profit margin will continue to be impacted by this utilized inventory and has also been impacted and may continue to be impacted by inventory acquisition costs. We expect gross profit margin to be variable for the foreseeable future as we work through our continued commercialization efforts.
    We began a controlled launch of the Platinum instrument and started to take orders in December 2022, and subsequently began a controlled commercial launch of Platinum in January 2023, and then moved to a full commercial launch of Platinum beginning in the second quarter of 2024. In January 2025, we announced the launch of our Platinum Pro benchtop sequencer. First shipments of Platinum Pro occurred in March 2025.
    Research and Development Expenses
    Research and development expenses primarily consist of personnel costs and benefits, stock-based compensation, lab supplies, consulting and professional services, fabrication services, charges related to product without an alternative future
    26

    Table of Contents
    use, facilities costs, software, and other outsourced expenses. Research and development expenses are recognized as incurred. Our research and development expenses are primarily related to developing new products and services.
    Research and development expenses for the three months ended March 31, 2025 and 2024 are as follows (dollars in thousands):
    Three months ended March 31,
    20252024$ Change% Change
    Research and development$13,717 $12,101 $1,616 13.4 %
    Research and development expenses increased by $1.6 million, or 13.4%, for the three months ended March 31, 2025, when compared to the same period in 2024. This increase was primarily due to a $1.7 million increase in fabrication and outsourced services, a $0.2 million increase in professional services and consulting fees and a $0.3 million net increase in other research and development expenses. These increases were partially offset by a $0.4 million decrease in payroll and payroll related costs and a $0.2 million decrease in laboratory supplies expense. In general, our research and development expenses have increased as we continue development on our recently announced Proteus platform.
    Selling, General and Administrative Expenses
    Selling, general and administrative expenses primarily consist of personnel costs and benefits, stock-based compensation, patent and filing fees, consulting and professional services, legal and accounting services, facilities costs, depreciation and amortization expense, insurance and office expenses, product advertising and marketing.
    Selling, general and administrative expenses for the three months ended March 31, 2025 and 2024 are as follows (dollars in thousands):
    Three months ended March 31,
    20252024$ Change% Change
    Selling, general and administrative$11,881 $11,528 $353 3.1 %
    Selling, general and administrative expenses increased $0.4 million, or 3.1%, for the three months ended March 31, 2025, when compared to the same period in 2024. This increase was primarily due to a $1.0 million increase in payroll and payroll related costs, which includes a $0.6 million increase in stock-based compensation expense. The remaining $0.4 million increase in payroll and payroll-related expenses includes a $0.6 million increase related to investments made in commercial operations offset by a $0.2 million reduction in general and administrative payroll and payroll related costs. These increases were partially offset by a $0.2 million decrease in legal fees, a $0.2 million decrease in depreciation and $0.3 million net decrease in other selling, general and administrative expenses.
    Dividend and Interest Income
    For the three months ended March 31, 2025 and 2024, dividend and interest income is derived primarily from fixed income securities and money market mutual funds.
    Dividend and interest income for the three months ended March 31, 2025 and 2024 are as follows (dollars in thousands):
    Three months ended March 31,
    20252024$ Change% Change
    Dividend and interest income$2,547 $3,574 $(1,027)(28.7)%
    Dividend and interest income decreased by $1.0 million, or 28.7% for the three months ended March 31, 2025, as compared to the same period in 2024. This decrease was a result of lower market interest rates on invested capital.
    27

    Table of Contents
    Change in Fair Value of Warrant Liabilities
    Warrant liabilities were recorded at fair value as part of the Business Combination. Change in fair value of warrant liabilities primarily consists of the change in the fair value of our Public Warrants and Private Warrants.
    Change in warrant liabilities for the three months ended March 31, 2025 and 2024 is as follows (dollars in thousands):
    Three months ended March 31,
    20252024$ Change% Change
    Change in fair value of warrant liabilities$3,401 $319 $3,082 966.1 %
    For the three months ended March 31, 2025, we recognized $3.4 million of income from the decrease in the fair value of warrant liabilities as compared to $0.3 million of income from the decrease in the fair value of warrant liabilities for the same period in 2024, an increase of $3.1 million, or 966.1%. These decreases in warrant value were primarily driven by the change in the underlying trading price of our Class A common stock during the periods reported.
    Other Expense, Net
    Other expense, net, typically consists of currency revaluations and income from credit card cash rewards programs. Other expense, net, for the three months ended March 31, 2025 and 2024 is as follows (dollars in thousands):
    Three months ended March 31,
    20252024$ Change% Change
    Other expense, net$(14)$(7)$(7)100.0 %
    Other expense, net, decreased for the three months ended March 31, 2025 as compared to the same period in 2024.
    Liquidity and Capital Resources
    The following table presents a summary of our condensed consolidated cash flows for operating, investing, and financing activities for the three months ended March 31, 2025 and 2024 (in thousands):
    Three months ended March 31,
    20252024
    Net cash used in operating activities$(26,154)$(23,208)
    Net cash used in investing activities(34,174)(57,428)
    Net cash provided by (used in) financing activities48,374 (56)
    Effect of exchange rate changes on cash and cash equivalents6 (5)
    Net decrease in cash and cash equivalents$(11,948)$(80,697)
    Net cash used in operating activities
    For the three months ended March 31, 2025, net cash used in operating activities of $26.2 million was primarily due to a net loss of $19.2 million resulting from continued spend on research and development and commercialization efforts, net changes in operating assets and liabilities of $6.1 million, a change in fair value of warrant liabilities of $3.4 million, primarily driven by the change in the underlying trading price of our Class A common stock, and accretion on marketable securities of $2.1 million partially offset by stock-based compensation of $2.4 million, depreciation and amortization of $0.9 million and write-downs of inventory of $0.7 million.
    For the three months ended March 31, 2024, net cash used in operating activities of $23.2 million was primarily due to a net loss of $19.5 million resulting from continued spend on research and development and commercialization efforts, net changes in operating assets and liabilities of $5.2 million and accretion on marketable securities of $2.1 million partially offset by stock-based compensation of $1.6 million and depreciation and amortization of $1.1 million.
    Net cash used in investing activities
    28

    Table of Contents
    For the three months ended March 31, 2025, net cash used in investing activities was $34.2 million compared to net cash used in investing activities of $57.4 million for the same period in 2024. This decrease in cash used was primarily due to a $64.3 million increase in cash provided by the sales and maturities of marketable securities partially offset by an increase in cash used to purchase marketable securities of $40.8 million.
    Net cash provided by (used in) financing activities
    For the three months ended March 31, 2025, net cash provided by financing activities was $48.4 million compared to cash used of $0.1 million for the same period in 2024. This increase in cash provided was due to $46.8 million of net proceeds from the Registered Direct Offering and $1.6 million of proceeds from the exercise of stock options. Further information regarding the Registered Direct Offering can be found below.
    Liquidity Outlook
    Since our inception, we have funded our operations primarily with proceeds from the issuance of equity to private investors, as well as with the proceeds received from the closing of the Business Combination. Additionally, we began to generate revenue during 2023 from commercial sales of our Platinum instrument. Our primary uses of liquidity have been operating expenses, capital expenditures and our acquisition of certain assets. Cash flows from operations have been historically negative as we continue to invest in the development of our technology in NGPS. Going forward, we anticipate debt or equity offerings will be the primary source of funds to support our operating needs and capital expenditures until we reach scale of our commercial operations. We expect to incur negative operating cash flows on an annual basis for the foreseeable future until such time that we can scale our revenue growth.
    We expect that our existing cash and cash equivalents and investments in marketable securities, together with revenue from the sale of our products and services, will be sufficient to meet our liquidity, capital expenditure, and anticipated working capital requirements and fund our operations for at least the next 12 months. We expect to use our cash and cash equivalents and investments in marketable securities and funds from revenue generated to invest in our continued commercialization efforts, to further invest in research and development, for other operating expenses, business acquisitions and for working capital and general corporate purposes.
    As of March 31, 2025, we had cash and cash equivalents and investments in marketable securities totaling $232.6 million. Our future capital requirements may vary from those currently planned and will depend on various factors including the pace and success of product commercialization.
    Our ongoing commercialization of our Platinum line of instruments as well as our continuing research and development efforts to enhance our instruments may require an accelerated amount of spending to enhance the sales and marketing teams, continue to drive development, and build inventory. Other factors that could accelerate cash needs include: (i) delays in achieving scientific and technical milestones, (ii) unforeseen capital expenditures and fabrication costs related to manufacturing for commercialization, (iii) changes we may make in our business or commercialization strategy, (iv) costs of running a public company, (v) other items affecting our forecasted level of expenditures and use of cash resources, including potential acquisitions, and (vi) increased product and service costs.
    On August 11, 2023, we filed a universal shelf registration statement on Form S-3 (the “Shelf Registration Statement”), which became effective on August 22, 2023, covering the offering of Class A common stock, preferred stock, debt securities, warrants, rights and units.
    On December 11, 2024, we entered into an Equity Distribution Agreement (the “Sales Agreement”) with Canaccord Genuity LLC (“Canaccord”) to sell shares of our Class A common stock, par value $0.0001, having an aggregate offering price of up to $75.0 million, from time to time through an “at-the-market” offering program under which Canaccord will act as sales agent. We have no obligation to sell any shares under the Sales Agreement and may at any time suspend solicitation and offers under the EDA. The ATM Offering is being made pursuant to our shelf registration and a prospectus supplement related to the ATM Offering dated December 11, 2024. During the year ended December 31, 2024, we sold and issued 23,425,650 shares of our Class A common stock under the ATM Offering, resulting in gross proceeds of $36.2 million. Net proceeds were $34.8 million after commissions and issuance costs of $1.4 million. We sold no shares of our Class A common stock under the ATM Offering for the three months ended March 31, 2025.
    On January 3, 2025, we entered into a securities purchase agreement with certain institutional investors pursuant to which we agreed to issue and sell, in a registered direct offering (the “Registered Direct Offering”) an aggregate of 15,625,000
    29

    Table of Contents
    shares of our Class A common stock at a price of $3.20 per Share. The gross proceeds from the Registered Direct Offering were $50.0 million. After deducting estimated placement agents’ fees and other offering expenses payable by the Company, net proceeds recorded during the three months ended March 31, 2025 were approximately $46.8 million.
    In the future, we may be unable to obtain any required additional financing on terms favorable to us, if at all. If adequate funds are not available to us on acceptable terms or otherwise, we may be unable to successfully develop or enhance products and services, respond to competitive pressure or take advantage of acquisition opportunities, any of which could have a material adverse effect on our business, financial condition, operating results and cash flows.
    Capital Expenditures
    We forecast capital expenditures in order to execute on our business plan and maintain growth; however, the actual amount and timing of such capital expenditures will ultimately be determined by the volume of business. We anticipate our future capital expenditures will be at approximately the same level as compared to the year ended December 31, 2024. We have funded and plan to continue funding these capital expenditures with cash and financing.
    Contractual Obligations
    We lease certain facilities and equipment under noncancellable lease agreements that expire at various dates through 2032. As of March 31, 2025, future lease payments, before adjustments for tenant incentives, were approximately $25.6 million.
    Licenses related to certain intellectual property
    We license certain intellectual property, some of which may be utilized in our current or future product offerings. To preserve the right to use such intellectual property, we are required to make annual minimum fixed payments totaling approximately $0.2 million as well as royalties based on net sales if the royalties exceed annual minimum fixed payments.
    Critical Accounting Policies and Significant Judgments and Estimates
    Our management’s discussion and analysis of our financial condition and results of operations is based on our Condensed Consolidated Financial Statements, which have been prepared in accordance with U.S. GAAP. The preparation of these Condensed Consolidated Financial Statements requires us to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the Condensed Consolidated Financial Statements, as well as expenses incurred during the reporting periods. Our estimates are based on historical experience and various other factors we believe to be reasonable under the circumstances, the results of which form the basis for making judgments about items not readily apparent from other sources. Actual results may differ from these estimates under different assumptions or conditions. Please refer to our critical accounting policies as disclosed in our Annual Report on Form 10-K for the year ended December 31, 2024 and Note 2. Summary of Significant Accounting Policies, in the accompanying notes to the Condensed Consolidated Financial Statements for a complete description of our significant accounting policies.
    Recently Issued Accounting Pronouncements
    Please refer to Note 2. Summary of Significant Accounting Policies, in the accompanying notes to the Condensed Consolidated Financial Statements included elsewhere in this Quarterly Report on Form 10-Q for a description of recently issued accounting pronouncements that may potentially impact our financial position and results of operations.
    Item 3.    Quantitative and Qualitative Disclosures About Market Risk
    Inflation risk
    We believe inflation can and has had an impact on the underlying cost of our supplies and manufacturing components related to our business. To the extent our costs are impacted by general inflationary pressures, we may not be able to fully offset such higher costs through price increases or manufacturing efficiencies. Our inability or failure to do so could harm our business, financial condition, results of operations or cash flows.
    Interest rate risk
    30

    Table of Contents
    As of March 31, 2025, our marketable securities are comprised primarily of investments in money market funds backed by U.S. government issued securities, U.S. Treasury bills, and high-quality corporate commercial paper. The primary objective of our investments is the preservation of capital to fulfill liquidity needs. We do not enter into investments for trading or speculative purposes. Based on the short-term nature of our holdings, future interest rate changes are not expected to have a material impact on our marketable securities.
    Foreign Currency Risk
    Presently, we operate our business primarily within the United States, with limited sales outside the United States. To date, we have executed the majority of our transactions in U.S. dollars. In the future, we anticipate expanding into Europe and other locations outside the United States. This expansion may include transacting business in currencies other than the U.S. Dollar. Despite this, we anticipate conducting limited activity outside the U.S. Dollar in the near term, and therefore foreign currency translation risk is not expected to have a material impact on our Condensed Consolidated Financial Statements. However, the growth of our operations, scope of transactions outside the United States, and the use of currencies other than the U.S. Dollar may grow in the future, at which point it is possible foreign currency translation will have a material effect on our operations. To date, we have not entered into any hedging arrangements with respect to foreign currency risk. As our international operations grow, we will continue to reassess our approach to managing our risk relating to fluctuations in currency rates.
    Item 4.    Controls and Procedures
    Evaluation of Disclosure Controls and Procedures
    Under the supervision and with the participation of our management, including our principal executive officer and principal financial officer, we conducted an evaluation of the effectiveness of the design and operation of our disclosure controls and procedures, as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act.
    Disclosure controls and procedures are controls and other procedures designed to ensure information required to be disclosed in our reports filed or submitted under the Exchange Act is recorded, processed, summarized and reported, within the time periods specified in the SEC’s rules and forms. Disclosure controls and procedures include controls and procedures designed to ensure information required to be disclosed in our reports filed under the Exchange Act is accumulated and communicated to management, including our Chief Executive Officer and Chief Financial Officer, to allow timely decisions regarding required disclosure. Based on the evaluation of our disclosure controls and procedures, our Chief Executive Officer and Chief Financial Officer concluded our disclosure controls and procedures were effective as of March 31, 2025.
    Changes in Internal Control over Financial Reporting
    There were no changes in our internal control over financial reporting during the quarter ended March 31, 2025 that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.
    31

    Table of Contents
    PART II - OTHER INFORMATION
    ITEM 1.    LEGAL PROCEEDINGS.
    From time to time, the Company is engaged in legal proceedings in the ordinary course of business. For further information on the Company’s legal proceedings, please refer to Note 17. Commitments and Contingencies, in the notes to the Condensed Consolidated Financial Statements.
    ITEM 1A. RISK FACTORS.
    Our business, results of operations, financial condition and cash flows are subject to various risks and uncertainties including the risk factors described under the caption “Risk Factors” in our Annual Report on Form 10-K for the year ended December 31, 2024, as filed with the SEC on March 3, 2025, and the risk factor described below.

    Our use of artificial intelligence and machine learning is subject to evolving laws and regulations and risks associated with unauthorized use, and may not result in the competitive advantages desired, all of which could expose us to competitive risk and legal liability.

    We use artificial intelligence, machine learning and automated decision-making technologies (“AI”) to assist in the performance, efficiency, and speed of various functions at the Company, including, but not limited to, general and administrative activities and research and development.

    The regulatory framework for AI is rapidly evolving as many federal, state and foreign government bodies and agencies have introduced or are currently considering additional laws and regulations for areas including but not limited to consumer protection and transparency, bias and discrimination, intellectual property, employment and use in regulated healthcare devices. Additionally, existing laws and regulations may be interpreted in ways that would affect the operation of AI at the Company. As a result, implementation standards and enforcement practices are likely to remain uncertain for the foreseeable future, and we cannot yet determine the impact future laws, regulations, standards, or market perception of their requirements may have on our business and may not always be able to anticipate how to respond to these laws or regulations. Further, the unauthorized use of AI tools can result in the exposure of sensitive data, including our intellectual property or trade secrets or the personal information of our employees, customers, or other business partners to unauthorized persons or to the public.

    There can be no assurance that we will realize the desired or anticipated benefits from AI, or any at all. Our use of AI could result in additional compliance costs, regulatory investigations and actions, and lawsuits; and If as a result, we are unable to use AI, it could make our business less efficient, result in competitive disadvantages, and our business, financial condition, results of operations and cash flows could be adversely affected.
    ITEM 2.    UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS.
    Unregistered Sales of Equity Securities and Use of Proceeds
    Not applicable.
    Issuer Purchases of Equity Securities
    Not applicable.
    ITEM 3.    DEFAULTS UPON SENIOR SECURITIES.
    Not applicable.
    ITEM 4.    MINE SAFETY DISCLOSURES.
    Not applicable.
    32

    Table of Contents
    ITEM 5.    OTHER INFORMATION.
    10b5-1 Trading Arrangements
    During the quarter ended March 31, 2025, no officers or directors, as defined in Rule 16a-1(f), adopted, modified or terminated a “Rule 10b5-1 trading arrangement” or a “non-Rule 10b5-1 trading arrangement,” as defined in Item 408 of Regulation S-K.
    33

    Table of Contents
    ITEM 6.    EXHIBITS.
    The following exhibits are filed as part of, or incorporated by reference into, this Quarterly Report on Form 10-Q.
    Exhibit
    Number
    Exhibit DescriptionFiled HerewithIncorporated by
    Reference Herein
    from
    Form or Schedule
    Filing Date
    3.1
    Second Amended and Restated Certificate of Incorporation of Quantum-Si Incorporated, as amended.Form 10-Q
    (Exhibit 3.1)
    8/7/2024
    3.2
    Amended and Restated Bylaws of Quantum-Si IncorporatedForm 10-K
    (Exhibit 3.2)
    3/1/2021
    31.1
    Certification of the Principal Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002X
    31.2
    Certification of the Principal Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002X
    32.1*
    Certification of the Principal Executive Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002X
    32.2*
    Certification of the Principal Financial Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002X
    101.INSInline XBRL Instance Document (the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document)X
    101.SCHInline XBRL Taxonomy Extension Schema DocumentX
    101.CALInline XBRL Taxonomy Extension Calculation Linkbase DocumentX
    101.DEFInline XBRL Taxonomy Extension Definition Linkbase DocumentX
    101.LABInline XBRL Taxonomy Extension Label Linkbase DocumentX
    101.PREInline XBRL Taxonomy Extension Presentation Linkbase DocumentX
    104Cover Page Interactive Data File (embedded within the Inline XBRL document)X
    *The certifications attached as Exhibit 32.1 and 32.2 that accompany this Quarterly Report on Form 10-Q are not deemed filed with the Securities and Exchange Commission and are not to be incorporated by reference into any filing of Quantum-Si Incorporated under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended (whether made before or after the date of such Form 10-Q), irrespective of any general incorporation language contained in such filing.
    34

    Table of Contents
    SIGNATURES
    Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
    QUANTUM-SI INCORPORATED
    Date: May 15, 2025
    By:
    /s/ Jeffrey Hawkins
    Jeffrey Hawkins
    President and Chief Executive Officer
    Date: May 15, 2025
    By:
    /s/ Jeffry Keyes
    Jeffry Keyes
    Chief Financial Officer and Treasurer
    35
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    • President & CEO Hawkins Jeffrey Alan sold $38,257 worth of shares (23,705 units at $1.61), decreasing direct ownership by 0.90% to 2,623,011 units (SEC Form 4)

      4 - Quantum-Si Inc (0001816431) (Issuer)

      6/24/25 7:14:41 PM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • Chief Product Officer Vieceli John S. sold $35,382 worth of shares (21,923 units at $1.61), decreasing direct ownership by 3% to 842,586 units (SEC Form 4)

      4 - Quantum-Si Inc (0001816431) (Issuer)

      6/24/25 7:11:15 PM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • GC & Corp. Secretary Lapointe Christian sold $19,280 worth of shares (11,946 units at $1.61), decreasing direct ownership by 1% to 971,534 units (SEC Form 4)

      4 - Quantum-Si Inc (0001816431) (Issuer)

      6/24/25 7:06:46 PM ET
      $QSI
      Industrial Machinery/Components
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    $QSI
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

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    • Chief Financial Officer Keyes Jeffry R. bought $43,465 worth of shares (50,000 units at $0.87), increasing direct ownership by 13% to 446,820 units (SEC Form 4)

      4 - Quantum-Si Inc (0001816431) (Issuer)

      8/13/24 6:01:25 AM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • President & CEO Hawkins Jeffrey Alan bought $21,272 worth of shares (25,000 units at $0.85), increasing direct ownership by 3% to 1,003,757 units (SEC Form 4)

      4 - Quantum-Si Inc (0001816431) (Issuer)

      8/13/24 6:01:28 AM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • Director Kummeth Charles R. bought $148,459 worth of shares (170,000 units at $0.87), increasing direct ownership by 92% to 355,000 units (SEC Form 4)

      4 - Quantum-Si Inc (0001816431) (Issuer)

      8/13/24 6:01:24 AM ET
      $QSI
      Industrial Machinery/Components
      Industrials

    $QSI
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    • Alliance Global Partners initiated coverage on Quantum-Si with a new price target

      Alliance Global Partners initiated coverage of Quantum-Si with a rating of Buy and set a new price target of $3.75

      2/7/25 8:29:38 AM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • H.C. Wainwright initiated coverage on Quantum-Si with a new price target

      H.C. Wainwright initiated coverage of Quantum-Si with a rating of Buy and set a new price target of $3.00

      12/8/23 7:55:31 AM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • Quantum-Si downgraded by Canaccord Genuity with a new price target

      Canaccord Genuity downgraded Quantum-Si from Buy to Hold and set a new price target of $2.00 from $3.50 previously

      9/25/23 9:04:14 AM ET
      $QSI
      Industrial Machinery/Components
      Industrials

    $QSI
    Leadership Updates

    Live Leadership Updates

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    • Quantum-Si Appoints Former Bio-Techne President and CEO, Chuck Kummeth, to serve as independent Chairman of the Board of Directors

      Quantum-Si Incorporated (NASDAQ:QSI) ("Quantum-Si," "QSI" or the "Company"), The Protein Sequencing Company™, today announced the appointment of Charles ("Chuck") Kummeth to the role of independent Chairman of the Board, effective May 27, 2024. Mr. Kummeth has over 35 years of leadership experience in Life Sciences most recently as President and CEO of Bio-Techne. During Mr. Kummeth's tenure at Bio-Techne, he oversaw tremendous growth across all aspects of the business including annual revenue growth from $300M to over $1.1B, growth in the employee base from 800 to over 3,000, and the successful execution of 19 acquisitions, all while maintaining a 35% or better EBITDA level. Under Mr. Ku

      5/30/24 4:05:00 PM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • Quantum-Si Appoints Former Illumina and Cisco Systems Executive, Paula Dowdy, to its Board of Directors

      Quantum-Si Incorporated (NASDAQ:QSI) ("Quantum-Si," "QSI" or the "Company"), The Protein Sequencing CompanyTM, today announced the appointment of Paula Dowdy, a senior executive with more than 35 years of experience across life sciences, enterprise software, and technology industries, to its Board of Directors. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20240321183506/en/Paula Dowdy (Photo: Business Wire) Ms. Dowdy currently serves on the Board of Directors for SPT Labtech, a world leading lab automation tools company based in the UK and is an advisor at EQT Life Sciences, one of Europe's leading investors targeting innovative

      3/21/24 4:05:00 PM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • Quantum-Si Introduces World's First Next-Generation Protein Sequencer™ in Japan with Addition of New Distributor

      Quantum-Si Incorporated (NASDAQ:QSI) ("Quantum-Si," "QSI" or the "Company"), The Protein Sequencing Company™, today announced that it has entered into an agreement with a new distributor who will make the company's protein sequencing instrument, Platinum® available for the first time in Japan. TOMY Digital Biology Co., Ltd., a renowned importer and distributor with a rich history dating back to the 1950s, will distribute Quantum-Si's next-generation protein sequencer™ and associated consumables throughout Japan. "Working with Quantum-Si marks a pivotal moment for TOMY Digital Biology, aligning with our commitment to advancing life sciences. We're poised to empower Japanese researchers wit

      1/18/24 8:30:00 AM ET
      $QSI
      Industrial Machinery/Components
      Industrials

    $QSI
    Financials

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    • Quantum-Si to Report First Quarter 2025 Financial Results on May 15, 2025

      Quantum-Si Incorporated (NASDAQ:QSI) ("Quantum-Si," "QSI" or the "Company"), The Protein Sequencing CompanyTM, today announced that it will report financial results for the first quarter 2025 on Thursday, May 15, 2025. Jeff Hawkins, President and Chief Executive Officer, and Jeff Keyes, Chief Financial Officer, will host a conference call to discuss financial results and provide a business update on the same day at 4:30 PM ET. Individuals interested in listening to the conference call may do so by joining the live webcast on the Investors section of the Quantum-Si website under Events and Presentations. Alternatively, individuals can register here to receive a dial-in number and personali

      4/24/25 8:00:00 AM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • Quantum-Si Reports Fourth Quarter and Full Year 2024 Financial Results

      Achieves First Quarterly Revenue Over $1 Million Completes Capital Raises of $86 Million Quantum-Si Incorporated (NASDAQ:QSI) ("Quantum-Si," "QSI" or the "Company"), The Protein Sequencing Company™, today announced financial results for the fourth quarter and full year ended December 31, 2024. Press Release Highlights Reported revenue of $1.2 million for the fourth quarter of 2024 and $3.1 million for the full year 2024 (representing a 183% full year-over-year growth) Raised capital of over $86 million between the fourth quarter of 2024 and first week of 2025 (extending cash runway into the second half of 2027) Announced the launch of Platinum® Pro in January 2025, with shipp

      3/3/25 4:05:00 PM ET
      $QSI
      Industrial Machinery/Components
      Industrials
    • Quantum-Si to Report Fourth Quarter and Full Year 2024 Financial Results on March 3, 2025

      Quantum-Si Incorporated (NASDAQ:QSI) ("Quantum-Si," "QSI" or the "Company"), The Protein Sequencing Company™, today announced that it will report financial results for the fourth quarter and full year 2024 on Monday, March 3, 2025. Jeff Hawkins, President and Chief Executive Officer, and Jeff Keyes, Chief Financial Officer, will host a conference call to discuss financial results and provide a business update on the same day at 4:30 PM ET. Individuals interested in listening to the conference call may do so by joining the live webcast on the Investors section of the Quantum-Si website under Events and Presentations. Alternatively, individuals can register here to receive a dial-in numbe

      2/12/25 8:00:00 AM ET
      $QSI
      Industrial Machinery/Components
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    $QSI
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

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    • Amendment: SEC Form SC 13D/A filed by Quantum-Si Incorporated

      SC 13D/A - Quantum-Si Inc (0001816431) (Subject)

      9/17/24 4:24:56 PM ET
      $QSI
      Industrial Machinery/Components
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    • Amendment: SEC Form SC 13G/A filed by Quantum-Si Incorporated

      SC 13G/A - Quantum-Si Inc (0001816431) (Subject)

      6/28/24 5:16:32 PM ET
      $QSI
      Industrial Machinery/Components
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    • SEC Form SC 13G filed by Quantum-Si Incorporated

      SC 13G - Quantum-Si Inc (0001816431) (Subject)

      2/13/24 9:41:18 AM ET
      $QSI
      Industrial Machinery/Components
      Industrials