SEC Form 10-Q filed by Silexion Therapeutics Corp
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(Exact name of registrant as specified in its charter)
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N/A
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(State or other jurisdiction of
incorporation or organization)
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(I.R.S. Employer
Identification No.)
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(Address of Principal Executive Offices, including zip code)
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(Registrant’s telephone number, including area code)
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N/A
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(Former name, former address and former fiscal year, if changed since last report)
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Title of each class
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Trading Symbol(s)
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Name of each exchange on which registered
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Large accelerated filer ☐
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Accelerated filer ☐
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Smaller reporting company
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Emerging growth company
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● | “we”, “us”, “our”, “the company”, “the Company”, “our company”, “the combined company”, “New Silexion”, or the “registrant” are to Silexion Therapeutics Corp (formerly known as Biomotion Sciences), a Cayman Islands exempted company, which is filing this Quarterly Report; | |
● | “A&R Sponsor Promissory Note” are to the convertible promissory note in a principal amount of $3,433,000 that our company issued to the Moringa sponsor at the Closing, in amendment and restatement of all promissory notes previously issued by Moringa to the sponsor for funds borrowed by Moringa from the sponsor between the initial public offering and the Closing of the Business Combination; | |
● | “Business Combination” are to the business combination transactions completed pursuant to the Business Combination Agreement, whereby, among other things: (i) Merger Sub 2 merged with and into Moringa, with Moringa continuing as the surviving company and a wholly-owned subsidiary of New Silexion; (ii) Merger Sub 1 merged with and into Silexion, with Silexion continuing as the surviving company and a wholly-owned subsidiary of New Silexion; (iii) the security holders of each of Moringa and Silexion exchanged their securities for securities of New Silexion at alternate, set exchange rates; (iv) the ordinary shares, warrants and units of Moringa were delisted from the Nasdaq Capital Market and deregistered under the Exchange Act; and (v) the ordinary shares and warrants of New Silexion issued in the Business Combination commenced trading on the Nasdaq Global Market; |
● | “Business Combination Agreement” are to the Amended and Restated Business Combination Agreement, dated April 3, 2024, by and among Moringa, New Silexion, August M.S. Ltd. (an Israeli company and a wholly owned subsidiary of New Silexion) (“Merger Sub 1”), Moringa Acquisition Merger Sub Corp (a Cayman Islands exempted company and a wholly owned subsidiary of New Silexion) (“Merger Sub 2”) and Silexion; |
● | “Closing” are to the closing of the Business Combination, which occurred on August 15, 2024; |
● | “Companies Law” are to the Companies Law (2021 Revision) of the Cayman Islands, as the same may be amended from time to time; |
● | “EarlyBirdCapital” or “EBC” are to EarlyBirdCapital, Inc., the representative of the underwriters of Moringa’s initial public offering; | |
● | “ELOC Agreement” or “White Lion Purchase Agreement” are to the Ordinary Share Purchase Agreement, dated August 13, 2024 and effective as of August 15, 2024, as amended as of January 14, 2025, by and between our company and White Lion Capital, LLC, which agreement established an equity line of credit for our company; | |
● | “Exchange Act” are to the U.S. Securities Exchange Act of 1934, as amended; |
● | “initial public offering” or “IPO” are to Moringa’s initial public offering of its Class A ordinary shares and warrants, which was consummated in two closings, on February 19, 2021 and March 3, 2021; |
● | “Marketing Agreement” are to the Business Combination Marketing Agreement, dated February 16, 2021, entered into by Moringa with EarlyBirdCapital in connection with the IPO; |
● | “Moringa” are to Moringa Acquisition Corp, a Cayman Islands exempted company, which was formerly a special purpose acquisition company, and, after the Business Combination, is a wholly-owned subsidiary of New Silexion; |
● | “Moringa sponsor” or “sponsor” are to Moringa Sponsor, LP, a Cayman Islands exempted limited partnership, which served as the sponsor of Moringa, and include, where applicable, its affiliates (including Moringa’s initial shareholder, Moringa Sponsor US L.P., a Delaware limited partnership, which is a wholly-owned subsidiary of Moringa sponsor, and Greenstar, L.P., a Cayman Islands exempted limited partnership which has the same general partner as Moringa Sponsor, LP); |
● | “ordinary shares” are to our ordinary shares, par value $0.0009 per share; | |
● | “private warrants” are to the 21,111 warrants, in the aggregate, issued to the Moringa sponsor and EarlyBirdCapital pursuant to the Business Combination in exchange, on a one-for-one basis, for Moringa warrants sold to them in private placements simultaneously with the closings of the initial public offering; |
● | “public warrants” are to our 638,888 warrants that we issued pursuant to the Business Combination to holders of, and in a one-for-one exchange for, Moringa’s public warrants that were initially issued and sold in Moringa’s initial public offering; |
● | “SEC” are to the U.S. Securities and Exchange Commission; |
● | “Securities Act” are to the U.S. Securities Act of 1933, as amended; |
● | “Silexion” are to Silexion Therapeutics Ltd., an Israeli company, which following the Business Combination is a wholly-owned subsidiary of New Silexion; | |
● | “trust account” are to the U.S.-based trust account that was maintained by Continental Stock Transfer & Trust Company acting as trustee, into which the proceeds from Moringa’s initial public offering and concurrent private placement were deposited, which proceeds were reduced due to redemptions of publicly-held Moringa Class A ordinary shares prior to the Business Combination and the remaining funds of which (after payment of fees owed to EarlyBirdCapital and other service providers of Moringa for services provided prior to the Closing) were transferred to the Company upon the Closing of the Business Combination; |
● | “warrants” are to our warrants to purchase ordinary shares, consisting of (i) public warrants and private warrants issued pursuant to the Business Combination in exchange for Moringa warrants, as well as (ii) warrants that we have issued and sold in public offering(s) and/or private placements subsequent to the Closing of the Business Combination; |
● | “2024 Annual Report” refer to our annual report on Form 10-K for the year ended December 31, 2024, which we filed with the SEC on March 18, 2025; and | |
● | “$,” “US$” and “U.S. dollar” each refer to the United States dollar. |
• | our ability to maintain the listing of our ordinary shares and our warrants on Nasdaq; |
• | our current and planned pre-clinical and clinical studies and trials involving our product candidates; |
• | our projected timeline for regulatory approvals of our product candidates; |
• | our market opportunity; |
• | our strategy, future operations, financial position, projected costs, prospects and plans; |
• | expectations regarding the time during which we will be an emerging growth company under the JOBS Act; |
• | our ability to retain or recruit officers, key employees and directors; |
• | the impact of the regulatory environment and complexities with compliance related to such environment; |
• | expectations regarding future partnerships or other relationships with third parties; and |
• | our future capital requirements and sources and uses of cash, including our ability to obtain additional capital in the future. |
• | we are a development-stage company and have a limited operating history on which to assess our business; |
• | we have never generated any revenue from product sales and may never be profitable; |
• | we will need to raise substantial additional funding, which may not be available on acceptable terms, or at all, and which will cause dilution to our shareholders; |
• | the approach we are taking to discover and develop novel RNAi therapeutics is unproven for oncology and may never lead to marketable products; |
• | we do not have experience producing our product candidates at commercial levels, currently have no marketing and sales organization, have an uncertain market receptiveness to our product candidates, and are uncertain as to whether there will be insurance coverage and reimbursement for our potential products; |
• | we may be unable to attract, develop and/or retain our key personnel or additional employees required for our development and future success; |
• | we may issue additional ordinary shares or other equity securities without your approval, including: (a) up to $15,337,500 of ordinary shares issuable under the ELOC Agreement (which includes shares already issued under that agreement); (b) ordinary shares underlying 4,138,211 outstanding warrants (as of March 31, 2025); and (c) ordinary shares underlying the A&R Sponsor Promissory Note, the issuance of which would dilute your ownership interest and may depress the market price of our ordinary shares; and |
• | those additional factors described in “Part I, Item 1A. Risk Factors” of the 2024 Annual Report. |
Page | |
CONSOLIDATED FINANCIAL STATEMENTS: | |
F -3 - F -4 | |
F -5 | |
F -6 | |
F -7 - F -8 | |
F -9 - F -18 |
_____________________________________
_____________________
March 31,
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December 31
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|||||||
2025
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2024
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|||||||
U.S. dollars in thousands
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||||||||
Assets
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||||||||
CURRENT ASSETS:
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Cash and cash equivalents
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$
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$
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Restricted cash
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Prepaid expenses
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Other current assets
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TOTAL CURRENT ASSETS
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NON-CURRENT ASSETS:
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Restricted cash
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Long-term deposit
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Property and equipment, net
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Operating lease right-of-use asset
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TOTAL NON-CURRENT ASSETS
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TOTAL ASSETS
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$
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$
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March 31,
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December 31
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|||||||
2025
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2024
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|||||||
U.S. dollars in thousands
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||||||||
Liabilities and shareholders’ equity (capital deficiency)
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||||||||
CURRENT LIABILITIES:
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Trade payables
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$
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$
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Current maturities of operating lease liability
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Employee related obligations
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Accrued expenses and other account payable
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Private warrants to purchase ordinary shares (including $
March 31, 2025 and December 31, 2024, respectively)
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Underwriters Promissory Note
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TOTAL CURRENT LIABILITIES
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NON-CURRENT LIABILITIES:
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Long-term operating lease liability
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Related Party Promissory Note
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TOTAL NON-CURRENT LIABILITIES
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$
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$
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TOTAL LIABILITIES
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$
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$
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||||
SHAREHOLDERS' EQUITY (CAPITAL DEFICIENCY): |
||||||||
Ordinary shares ($
and December 31, 2024;
March 31, 2025 and December 31, 2024, respectively)
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Additional paid-in capital
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Accumulated deficit
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(
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)
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(
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)
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||||
TOTAL SHAREHOLDERS' EQUITY (CAPITAL DEFICIENCY)
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$
|
|
$
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(
|
)
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|||
TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY (CAPITAL DEFICIENCY)
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$
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$
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Three months ended
March 31
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||||||||
2025
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2024
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U.S. dollars in thousands
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OPERATING EXPENSES:
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Research and development (including $
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$
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$
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General and administrative (including $
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TOTAL OPERATING EXPENSES
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OPERATING LOSS
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Financial expenses, net (including $
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||||||
LOSS BEFORE INCOME TAX
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$
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$
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INCOME TAX
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NET LOSS
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$
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$
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||||
Attributable to:
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||||||||
Equity holders of the Company
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Non-controlling interests
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$
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$
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LOSS PER SHARE, BASIC AND DILUTED
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$
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$
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** | |||
WEIGHTED AVERAGE NUMBER OF ORDINARY SHARES OUTSTANDING USED IN COMPUTATION OF BASIC AND DILUTED LOSS PER SHARE
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** |
** All share and per share amounts for the three months ended March 31, 2024 have been retroactively adjusted to reflect a 1-for-
9 reverse share split that was effected on November 29, 2024, as discussed in Note 1g
The accompanying notes are an integral part of the unaudited condensed consolidated financial statements.
Redeemable Convertible Preferred Shares
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Ordinary shares
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Additional
paid-in Capital |
Accumulated deficit
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Total shareholders’ equity (capital deficiency)
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Total redeemable convertible preferred shares and contingently redeemable non-controlling interests, net of shareholders’ equity (capital deficiency)
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|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Series A preferred shares
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Series A-1 preferred shares
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Series A-2 preferred shares
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Series A-3 preferred shares
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Series A-4 preferred shares
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Contingently redeemable non-controlling
interests
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|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Shares
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Amount
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Shares
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Amount
|
Shares
|
Amount
|
Shares
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Amount
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Shares
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Amount
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Amount
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Shares
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Amount
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||||||||||||||||||||||||||||||||||||||||||||||||||||||||
BALANCE AT JANUARY 1, 2024
|
|
$
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|
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$
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|
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$
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|
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$
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$
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|
$
|
|
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$
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$
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(
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)
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$
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(
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)
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$
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|||||||||||||||||||||||||||||||||||||||
CHANGES DURING THE 3 MONTHS PERIOD ENDED MARCH 31, 2024 (unaudited):
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Exercise of options
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**
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Share-based compensation
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Net loss
|
(
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)
|
(
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)
|
(
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)
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(
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)
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BALANCE AS OF MARCH 31, 2024
|
|
$
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$
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$
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$
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$
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|
|
|
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$
|
|
$
|
(
|
)
|
$
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(
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)
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$
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||||||||||||||||||||||||||||||||||||||||
BALANCE AT JANUARY 1, 2025
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$ |
$
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$
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(
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)
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$
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(
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)
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$
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(
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)
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||||||||||||||||||||||||||||||||||||||||||||
CHANGES DURING THE 3 MONTHS PERIOD ENDED MARCH 31, 2025:
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Issuance of ordinary shares and warrants upon public offering, net of issuance costs and exercise of pre-funded warrants to ordinary shares (see Note 4(a))
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Exercise of warrants (see Note 4(a))
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Issuance of ordinary shares and warrants upon warrants inducement, net of issuance costs (see Note 4(b))
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Share-based compensation
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Conversion of EarlyBird Promissory Note (see Note 5)
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Net loss
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(
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)
|
(
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)
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(
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)
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BALANCE AS OF MARCH 31, 2025
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-,
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-,
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-,
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-,
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-,
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-,
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-,
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-,
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-,
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-,
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-,
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***
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$
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$
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$
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(
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)
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$
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$
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|
Three months ended
March 31
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2025
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2024
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U.S. dollars in thousands
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CASH FLOWS FROM OPERATING ACTIVITIES:
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Net loss
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$
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(
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)
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$
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(
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)
|
||
Adjustments required to reconcile loss to net cash used in operating activities:
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Depreciation
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Share-based compensation expenses
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Non-cash financial expenses
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Changes in operating assets and liabilities:
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Increase in prepaid expenses
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(
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)
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(
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)
|
||||
Decrease (increase) in other receivables
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(
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)
|
|||||
Decrease in trade payable
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(
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)
|
(
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)
|
||||
Net change in operating lease
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(
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)
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Increase (decrease) in employee related obligations
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(
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)
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Decrease in accrued expenses
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(
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)
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(
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)
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Net cash used in operating activities
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(
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)
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(
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)
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CASH FLOWS FROM INVESTING ACTIVITIES:
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Purchase of property and equipment
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(
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)
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(
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)
|
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Net cash used in investing activities
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(
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)
|
(
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)
|
||||
CASH FLOWS FROM FINANCING ACTIVITIES:
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Exercise of options
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Proceeds from issuance of ordinary shares upon public offering
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Issuance costs related to public offering
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(
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)
|
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Proceeds from exercise of warrants
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Proceeds from issuance of ordinary shares upon warrants inducement
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Issuance costs related to warrants inducement
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(
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)
|
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Payment of Underwriters Promissory Note
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(
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)
|
|
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Net cash provided by financing activities
|
|
|
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DECREASE IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH
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(
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)
|
|||||
EXCHANGE RATE DIFFERENCES ON CASH AND CASH EQUIVALENTS AND RESTRICTED CASH
|
(
|
)
|
(
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)
|
||||
BALANCE OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT BEGINNING OF PERIOD
|
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|
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BALANCE OF CASH, CASH EQUIVALENTS AND RESTRICTED CASH AT END OF PERIOD
|
$
|
|
$
|
|
Three months ended
March 31
|
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2025
|
2024
|
|||||||
U.S. dollars in thousands
|
||||||||
Appendix A -
RECONCILIATION OF CASH, CASH EQUIVALENTS AND RESTRICTED
CASH REPORTED IN THE CONSOLIDATED BALANCE SHEETS:
|
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Cash and cash equivalents
|
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|
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Restricted cash
|
|
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||||||
TOTAL CASH, CASH EQUIVALENTS AND RESTRICTED CASH SHOWN IN STATEMENT OF CASH FLOWS
|
$
|
|
$
|
|
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Appendix B - SUPPLEMENTARY INFORMATION:
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SUPPLEMENTARY INFORMATION ON INVESTING AND
FINANCING ACTIVITIES NOT INVOLVING CASH FLOWS:
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Conversion of Promissory Note to ordinary shares
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$
|
|
$
|
|
||||
Accrued and unpaid issuance expenses in respect of public offering and warrants inducement transactions
|
$
|
|
$
|
|
||||
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:
|
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Interest paid
|
$
|
|
$
|
|
||||
Interest received
|
$
|
|
$
|
|
SILEXION THERAPEUTICS CORP
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (UNAUDITED)
(U.S. dollars in thousands)
a. |
Silexion Therapeutics Corp (“New Silexion”) (hereinafter - the “Company” or the “Combined Company”) is an entity that was formed for the purpose of effecting the Transactions (see below), and now serves as a publicly-traded holding company of its subsidiaries — including Moringa Acquisition Corp (“Moringa” or “the SPAC”), a Cayman Islands exempted company and Silexion Therapeutics Ltd. (formerly known as Silenseed Ltd.) (“Silexion”), an Israeli limited company— after the closing of the Transactions (the “Closing”).
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b. |
From its formation on April 2, 2024 until the consummation of the Transactions on August 15, 2024, the Company had no operations and had been formed for the sole purpose of entering into the Transactions and serving as the publicly-traded company following the Transactions. Silexion, on the other hand, as the accounting acquirer in the Transactions and the predecessor entity to the Company from an accounting perspective, had active operations during earlier periods of time, prior to the Transactions. Consequently, these financial statements reflect the financial information of Silexion (as the predecessor entity to the Company) until August 15, 2024 and the financial information of New Silexion (as the combined company following the Transactions) from that date forward.
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c. |
On April 3, 2024, Silexion entered into an Amended and Restated Business Combination Agreement (hereinafter, the “A&R BCA”) with the SPAC, New Silexion, August M.S. Ltd. an Israeli company and wholly-owned subsidiary of New Silexion (“Merger Sub 1”), and Moringa Acquisition Merger Sub Corp, a Cayman Islands exempted company and wholly-owned subsidiary of New Silexion (“Merger Sub 2”). Under the A&R BCA, both Silexion and the SPAC were to become wholly-owned subsidiaries of New Silexion, which was to become a publicly-held, Nasdaq-listed entity (the A&R BCA and related transactions: the “Transactions”).
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d. |
On August 15, 2024, the parties completed the Transactions pursuant to which Merger Sub 2 merged with and into the SPAC, with the SPAC continuing as the surviving company of such merger and a wholly-owned subsidiary of New Silexion (the “SPAC Merger”), and Merger Sub 1 merged with and into Silexion, with Silexion continuing as the surviving company of such merger and a wholly-owned subsidiary of New Silexion (the “Acquisition Merger”).
|
e. |
In connection with the closing of the Transactions, the ordinary shares and warrants of New Silexion are now listed on the Nasdaq Global Market and began trading under the symbols “SLXN” and “SLXNW”, respectively.
|
f. |
In October 2024, Hamas terrorists infiltrated Israel’s southern border from the Gaza Strip and conducted a series of attacks on civilian and military targets. Following the attack, Israel’s security cabinet declared war against Hamas and commenced a military campaign against Hamas and other terrorist organizations.
The Company’s headquarters are located in the central region of Israel. As of the issuance date of these consolidated financial statements, the conflict between Israel and Hamas has not had a material impact on the Company’s results of operations or financial position, if at all. The Company cannot currently predict the intensity or duration of Israel’s war against Hamas, however, as most of the Company’s trials are not executed in Israel, the Company does not believe the recent terrorist attack and the subsequent declaration of war by the Israeli government against the Hamas terrorist organization will have any material impact on its ongoing operations. The Company continues to monitor its ongoing activities and will make any needed adjustments to ensure continuity of its business, while supporting the safety and well-being of its employees.
Any hostilities involving Israel, or the interruption or curtailment of trade within Israel or between Israel and its trading partners could adversely affect the Company’s operations and results of operations and could make it more difficult for the Company to raise capital.
|
F -9
g. |
On November 22, 2024, the Company announced a prospective
|
h. |
Going concern:
Since its inception, the Company has devoted substantially all its efforts to research and development, clinical trials, and capital raising activities. The Company is still in its development and clinical stage and has not yet generated revenues.
The Company (or, for those periods prior to the Transactions, its predecessor, Silexion) has incurred losses of $
The Company expects to continue incurring losses, and negative cash flows from operations. Management is in the process of evaluating various financing alternatives, including financing via the ELOC Agreement, as the Company will need to finance future research and development activities, general and administrative expenses and working capital through fund raising. However, there is no assurance that the Company will be successful in obtaining such funding.
Under these circumstances, in accordance with the requirements of ASC 205-40, management has concluded that there is substantial doubt about the Company’s ability to continue as a going concern for at least 12 months from the date these financial statements are issued. The unaudited condensed consolidated financial statements do not include any adjustments that might result from the outcome of this uncertainty.
|
a. |
Unaudited Condensed Financial Statements
The accompanying condensed financial statements are unaudited. These unaudited interim condensed consolidated financial statements have been prepared in accordance with generally accepted accounting principles in the United States of America ("U.S. GAAP") for interim financial statements and follow the requirements of the Securities and Exchange Commission (“SEC”) for interim financial reporting. Accordingly, they do not include all of the information and notes required by U.S. GAAP for annual financial statements. In the opinion of management, these unaudited condensed consolidated financial statements reflect all adjustments, which include normal and recurring adjustments, necessary for a fair statement of the Company’s consolidated financial position as of March 31, 2025, and the consolidated results of operations, statements of changes in redeemable convertible preferred shares and shareholders’ equity (capital deficiency) and cash flows for the three-month period ended March 31, 2025 and 2024.
The consolidated results for the three-month ended March 31, 2025 are not necessarily indicative of the results to be expected for the year ending December 31, 2025.
These unaudited interim condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and the related notes of the Company as of and for the year ended December 31, 2024, included in the Company’s Annual Report on Form 10-K filed with the SEC on March 18, 2025. The significant accounting policies adopted and used in the preparation of the financial statements are consistent with those of the previous financial year.
|
F -10
b. |
Use of estimates
The preparation of the financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the amounts reported in the financial statements and accompanying notes. As applicable to these financial statements, the most significant estimates and assumptions relate to fair value of financial instruments. See Note 7, respectively. These estimates and assumptions are based on current facts, future expectations, and various other factors believed to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities and the recording of expenses that are not readily apparent from other sources. Actual results may differ materially and adversely from these estimates.
|
c. |
Restricted cash
As of March 31, 2025 and December 31, 2024, the Company pledged an amount of $
The Company is required to hold a minimum amount of NIS
|
d. |
Fair value measurement
Fair value is based on the price that would be received from the sale of an asset or that would be paid to transfer a liability in an orderly transaction between market participants at the measurement date. In order to increase consistency and comparability in fair value measurements, the guidance establishes a fair value hierarchy that prioritizes observable
and unobservable inputs used to measure fair value into three broad levels, which are described as follows:
|
Level 1: |
Quoted prices (unadjusted) in active markets that are accessible at the measurement date for assets or liabilities. The fair value hierarchy gives the highest priority to Level 1 inputs.
|
Level 2: |
Observable prices that are based on inputs not quoted on active markets, but corroborated by market data or active market data of similar or identical assets or liabilities.
|
Level 3: |
Unobservable inputs are used when little or no market data is available. The fair value hierarchy gives the lowest priority to Level 3 inputs.
|
In determining fair value, the Company utilizes valuation techniques that maximize the use of observable inputs and minimize the use of unobservable inputs to the extent possible and considers counterparty credit risk in its assessment of fair value.
|
e. |
Concentration of credit risks
Financial instruments that potentially subject the Company to concentration of credit risk consist principally of cash and cash equivalents and restricted cash. The Company deposits cash and cash equivalents mostly with three low risk financial institution. The Company has not experienced any material credit losses in these accounts and does not believe it is exposed to significant credit risk on these instruments.
|
F -11
f. |
Recently Adopted accounting pronouncements:
In June 2022, the FASB issued ASU 2022-03 “Fair Value Measurement of Equity Securities Subject to Contractual Sale Restrictions”. The ASU clarifies that a contractual restriction on the sale of an equity security is not considered part of the unit of account of the equity security and, therefore, is not considered in measuring its fair value. The ASU also clarifies that an entity cannot, as a separate unit of account, recognize and measure a contractual sale restriction. The ASU also introduces new disclosure requirements for equity securities subject to contractual sale restrictions. The Company adopted the ASU on January 1, 2025 and it did not have a material impact on its consolidated financial statement.
There have been no changes to the recently issued accounting pronouncements not yet adopted that were previously disclosed in the Annual Report.
|
a. |
Research and development expenses:
|
Three months ended
March 31
|
||||||||
2025
|
2024
|
|||||||
Payroll and related expenses
|
$
|
|
$
|
|
||||
Share-based compensation expenses
|
|
|
||||||
Subcontractors and consultants
|
|
|
||||||
Rent and maintenance
|
|
|
||||||
Other
|
|
|
||||||
$
|
|
$
|
|
b. |
General and administrative expenses:
|
Payroll and related expenses
|
$
|
|
$
|
|
||||
Share-based compensation expenses
|
|
|
||||||
Professional services
|
|
|
||||||
Depreciation
|
|
|
||||||
Rent and maintenance
|
|
|
||||||
Patent registration
|
|
|
||||||
Travel expenses
|
|
|
||||||
Other
|
|
|
||||||
$
|
|
$
|
|
c. |
Financial expense, net:
|
Change in fair value of financial liabilities measured at fair value
|
$
|
|
$
|
|
||||
Interest expense (income), net
|
|
(
|
)
|
|||||
Foreign currency exchange loss (income), net
|
(
|
)
|
|
|||||
Other
|
|
|
||||||
Total financial expense (income), net
|
$
|
|
$
|
|
F -12
a. |
Public Offering of Ordinary Shares, Pre-Funded Warrants, and Ordinary Warrants.
On January 15, 2025, and January 17, 2025, the Company offered and sold (the “Offering”)
The pre-funded warrants are immediately exercisable at an exercise price of $
Applying ASC 815-40, the Company concluded that the pre-funded warrants and ordinary warrants are considered indexed to the Company’s own stock and meet the conditions for equity classification, and thus should be presented within equity.
The Company also issued its placement agent warrants to purchase up to
As of March 31, 2025, a total of
|
b. |
Induced Warrant Exercise Transaction
On January 29, 2025, the Company entered into an inducement offer letter agreement with holders of (“Inducement Offer”)
Upon exercise for cash of any New Ordinary Warrants, in certain circumstances, the placement agent will receive a cash fee of 8.0% of the aggregate gross exercise price. The Company also issued the placement agent warrants to purchase up to Both the New Ordinary Warrants and the placement agent warrants are immediately exercisable from the date of issuance until the 24-month anniversary of the effective date of the resale registration statement. |
F -13
During January 2025, the Company has repaid $
On March 13, 2025 the Company entered into a letter agreement (the “Note Conversion Inducement Agreement”) with EarlyBird, under which the then outstanding principal amount and accrued interest of the Convertible Promissory Note issued to EarlyBird of $ |
The Company's share-based compensation expenses amounted to a total of $
Summary of outstanding and exercisable options:
Below is a summary of the Company's share-based compensation activity and related information with respect to options granted to employees and non-employees for the three months ended March 31, 2025:
|
Number of options
|
Weighted-average exercise price (in U.S. dollars)
|
Weighted- average remaining contractual term
(in years)
|
Aggregate
intrinsic
value
|
|||||||||||||
Outstanding at January 1, 2025
|
|
|
|
-
|
||||||||||||
Granted
|
|
|
|
-
|
||||||||||||
Exercised
|
|
|
-
|
-
|
||||||||||||
Forfeited
|
|
|
-
|
-
|
||||||||||||
Expired
|
(
|
)
|
|
-
|
-
|
|||||||||||
Outstanding at March 31, 2025
|
|
|
|
-
|
||||||||||||
Exercisable at March 31, 2025
|
|
|
|
-
|
||||||||||||
Vested and expected to vest at March 31, 2025
|
|
|
|
-
|
In 2024 no options were granted.
On February 9, 2025, Silexion’s board of directors approved granting |
F -14
RSUs granted to employees and non-employees:
On February 9, 2025, Silexion’s board of directors approved granting
The share-based compensation expense by line item in the accompanying consolidated statements of operations is summarized as follows:
|
Three months ended
March 31
|
||||||||
2025
|
2024
|
|||||||
Research and development
|
$
|
|
$
|
|
||||
General and administrative
|
|
|
||||||
$
|
|
$
|
|
Financial instruments measured at fair value on a recurring basis
The Company’s assets and liabilities that are measured at fair value as of March 31, 2025, and December 31, 2024, are classified in the tables below in one of the three categories described in “Note 2 – Fair value measurement”:
|
March 31, 2025
|
||||||||
Level 3
|
Total
|
|||||||
Financial Liabilities
|
||||||||
|
|
|
|
|||||
Private Warrants to ordinary shares
|
$
|
|
$
|
|
||||
Promissory Notes
|
$ |
|
$ |
|
December 31, 2024
|
||||||||
Level 3
|
Total
|
|||||||
Financial Liabilities
|
||||||||
Private Warrants to ordinary shares
|
$
|
|
$
|
|
||||
Promissory Notes
|
$
|
|
$
|
|
The following is a roll forward of the fair value of liabilities classified under Level 3:
|
Three months ended March 31,
|
||||||||||||
2025
|
2024
|
|||||||||||
Promissory Notes
|
Private Warrants to ordinary shares
|
Warrants to preferred shares
|
||||||||||
Fair value at the beginning of the period
|
$
|
|
$
|
|
$
|
|
||||||
Change in fair value
|
|
(
|
)
|
|
||||||||
Repayments
|
(
|
)
|
|
|
||||||||
Conversion to equity
|
(
|
)
|
|
|
||||||||
Fair value at the end of the period
|
$
|
|
$
|
|
$
|
|
Promissory Notes In measuring the fair value of the Company’s Promissory Notes, a discount rate of
|
F -15
Warrants over ordinary shares
A Black-Scholes-Merton model with Level 3 inputs was used to calculate the Company’s warrants’ fair value. Inherent in a Black-Scholes-Merton model are assumptions related to expected life (term), expected stock price, volatility, risk-free interest rate and dividend yield. The Company estimates the volatility of its warrants based on implied volatility from the Company’s traded warrants and from historical volatility of selected peer companies’ Class A ordinary shares that matches the expected remaining life of the warrants. The risk-free interest rate is based on the U.S. Treasury zero-coupon yield curve on the grant date for a maturity similar to the expected remaining life of the warrants. The expected life of the warrants is assumed to be equivalent to their remaining contractual term. The dividend rate is based on the historical rate, which the Company anticipates will remain at zero.
The following table provides quantitative information regarding Level 3 fair value measurement inputs of the warrants:
|
March 31
|
||||
|
2025
|
|||
Volatility
|
|
%
|
||
Dividend yield
|
|
%
|
Financial instruments not measured at fair value The carrying amounts of cash and cash equivalents, restricted cash, receivables, trade payables and other liabilities approximate their fair value due to the short-term maturity of such instruments.
|
The following table sets forth the computation of basic and diluted net loss per share attributable to ordinary shareholders for the periods presented (USD in thousands, except per share data):
|
Three months ended
March 31
|
||||||||
2025
|
2024
|
|||||||
Numerator:
|
||||||||
Net loss for the year
|
$
|
|
$
|
|
||||
Net loss attributable to ordinary shareholders, basic and diluted:
|
$
|
|
$
|
|
||||
Denominator:
|
||||||||
Weighted-average shares used in computing net loss per share attributable to ordinary shareholders, basic and diluted
|
|
|
||||||
Net loss per share attributable to ordinary shareholders, basic and diluted
|
$
|
|
$
|
|
Basic loss per share is computed on the basis of the net loss for the period divided by the weighted average number of ordinary shares outstanding during the period, including fully vested pre-funded options for the Company’s ordinary shares at an exercise price of $ As of March 31, 2025 and March 31, 2024, the basic loss per share calculation included a weighted average number of
|
F -16
The following instruments were not included in the computation of diluted earnings per share because of their anti-dilutive effect:
For the period ending on March 31, 2025
|
- |
Warrants to purchase Ordinary Shares (see also Note 4).
|
- |
Share-based compensation
|
- |
Promissory Notes (see also Note 5).
|
For the period ending on March 31, 2024:
|
- |
Redeemable convertible preferred shares;
|
- |
Warrants to purchase redeemable convertible preferred shares; |
- |
Share-based compensation
|
Transactions with related parties which are shareholders and directors of the Company:
|
a. |
Transactions:
|
March 31
|
||||||||
2025
|
2024
|
|||||||
Share-based compensation included in research and development expenses
|
$
|
|
$
|
|
||||
Share-based compensation included in general and administrative expenses
|
$
|
|
$
|
|
||||
Financial expenses
|
$
|
|
$
|
|
b. |
Balances:
|
March 31,
2025
|
December 31,
2024
|
|||||||
Current liabilities —
|
||||||||
Private warrants to purchase ordinary shares
|
$
|
|
$
|
|
||||
$
|
|
$
|
|
March 31,
2025
|
December 31,
2024
|
|||||||
Non-Current liabilities —
|
||||||||
Sponsor Promissory Note
|
$
|
|
$
|
|
||||
$
|
|
$
|
|
F -17
The Company operates as a single operating segment in the research and development of innovative treatments for pancreatic cancer based on siRNAs. The Company’s CODM is its Chief Executive Officer (CEO). The CODM reviews the Company’s performance on a consolidated basis. As such, the segment’s loss is the Company’s consolidated net loss and the segment’s assets are the Company’s consolidated assets.
The CODM uses the information primarily to evaluate the Company’s performance and allocate resources. This includes reviewing key financial metrics such as budget versus actual expenditures, tracking progress on research and development milestones, and assessing overall cash flow and liquidity to ensure the continuity of operations. This approach allows the CODM to monitor the Company's performance and make strategic adjustments as needed to support its operational and financial goals.
The CODM reviews the Company’s results on a consolidated basis. As such, information on segment loss and significant expenses is similar to the Company’s consolidated statements of operations. The CODM is also regularly provided with information on significant ordinary-course expenses, including the following expenses. the management does not segregate its business for internal reporting.
|
Three months ended
March 31
|
||||||||
2025
|
2024
|
|||||||
Clinical trials and other payments to R&D-related service providers
|
$
|
|
$
|
|
||||
Payroll and related expenses, other than share-based compensation
|
|
|
||||||
Share-based compensation expenses
|
|
|
||||||
Depreciation expenses
|
|
|
||||||
Other segment expenses (*)
|
|
|
||||||
Operating loss
|
|
|
||||||
Interest income
|
(
|
)
|
(
|
)
|
||||
Interest expense
|
|
|
||||||
Other financing expense (income), net
|
|
|
||||||
Income taxes
|
|
|
|
|||||
Net loss
|
$
|
|
$
|
|
||||
Segment assets
|
$
|
|
$
|
|
||||
Expenditures for segment assets
|
(
|
)
|
(
|
)
|
(*) |
Other segment expenses include mainly general and administrative-related expenses, such as payments to advisors and consultants, office lease expenses and maintenance, HR and legal expenses.
|
(**) |
Represents an amount less than $1
|
F -18
• | apply for Orphan Drug Designation in both the U.S. and EU for our SIL204 product; |
• | conduct toxicological studies with respect to SIL204; |
• | initiate a clinical trial powered for statistical significance with respect to SIL204; |
• | seek marketing approvals for SIL204 in various territories; |
• | maintain, expand and protect our intellectual property portfolio; |
• | hire additional operational, clinical, quality control and scientific personnel; |
• | add additional product candidates to our pipeline; |
• | add operational, financial and management information systems and personnel, including personnel to support our product development, any future commercialization efforts and our status as a public company; and |
• | invest in research and development and regulatory approval efforts in order to utilize our technology as a platform focused on the silencing of the KRAS oncogene using RNA-interference therapeutics. |
Three-month period ended March 31, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Operating expenses: | ||||||||
Research and development | $ | 590 | $ | 961 | ||||
General and administrative | 1,060 | 289 | ||||||
Total operating expenses | 1,650 | 1,250 | ||||||
Operating loss | 1,650 | 1,250 | ||||||
Financial expenses, net | 85 | 168 | ||||||
Loss before income tax | 1,735 | 1,418 | ||||||
Income tax | * | 5 | ||||||
Net loss for the quarter | $ | 1,735 | $ | 1,423 |
Three-month period ended March 31, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Payroll and related expenses | $ | 369 | $ | 260 | ||||
Share-based compensation expenses | - | 19 | ||||||
Subcontractors and consultants | 156 | 631 | ||||||
Rent and maintenance | 40 | 31 | ||||||
Other | 25 | 20 | ||||||
Total research and development expenses | $ | 590 | $ | 961 |
Three-month period ended March 31, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Payroll and related expenses | $ | 332 | $ | 129 | ||||
Share-based compensation expenses | 21 | 13 | ||||||
Professional service | 525 | 79 | ||||||
Depreciation | 4 | 8 | ||||||
Rent and maintenance | 30 | 26 | ||||||
Patent registration | 4 | 9 | ||||||
Travel expenses | 54 | 9 | ||||||
Other | 90 | 16 | ||||||
Total general and administrative expenses | $ | 1,060 | $ | 289 |
Three-month period ended March 31, | ||||||||
2025 | 2024 | |||||||
(U.S. dollars, in thousands) | ||||||||
Cash and cash equivalents and restricted cash at beginning of the period | $ | 1,270 | $ | 4,645 | ||||
Net cash used in operating activities | (2,453 | ) | (1,752 | ) | ||||
Net cash used in investing activities | (6 | ) | (6 | ) | ||||
Net cash provided by financing activities | 7,432 | * | ||||||
Net increase (decrease) in cash and cash equivalents and restricted cash | $ | 4,973 | $ | (1,758 | ) | |||
Translation adjustments on cash and cash equivalents and restricted cash | (10 | ) | (56 | ) | ||||
Cash and cash equivalents and restricted cash at end of the period | $ | 6,233 | $ | 2,831 |
• | Material cost. |
• | Regulatory pathway; and |
• | Human clinical trial costs. |
• | significant dilution to the equity interests of our current shareholders; |
• | a deemed change of control of our company due to the issuance of a substantial number of ordinary shares, which may affect, among other things, our ability to use our net operating loss carry forwards, if any, and could result in a change in the officers and directors of our company relative to our current officers and directors, to the extent any shareholders build up significant beneficial ownership from ordinary shares issued pursuant to public offerings, warrant exercises or the ELOC; |
• | may have the effect of delaying or preventing a change of control of our company by diluting the share ownership or voting rights of a person seeking to obtain control; and |
• | may adversely affect prevailing market prices for our ordinary shares or warrants. |
No. | Description of Exhibit | |
101.INS* | Inline XBRL Instance Document. | |
101.SCH* | Inline XBRL Taxonomy Extension Schema Document. | |
101.CAL* | Inline XBRL Taxonomy Extension Calculation Linkbase Document. | |
101.DEF* | Inline XBRL Taxonomy Extension Definition Linkbase Document. | |
101.LAB* | Inline XBRL Taxonomy Extension Label Linkbase Document. | |
101.PRE* | Inline XBRL Taxonomy Extension Presentation Linkbase Document. | |
104* | Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101). |
* | Filed herewith. |
** | Furnished herewith. |
SILEXION THERAPEUTICS CORP | ||
Date: May 13, 2025 | /s/ Ilan Hadar | |
Name: | Ilan Hadar | |
Title: | Chairman and Chief Executive Officer | |
(Principal Executive Officer) | ||
Date: May 13, 2025 | /s/ Mirit Horenshtein-Hadar | |
Name: | Mirit Horenshtein-Hadar | |
Title: | Chief Financial Officer | |
(Principal Financial and Accounting Officer) |
16