• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Dashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlerts
    Company
    AboutQuantisnow PlusContactJobs
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form 4 filed by Large owner Griffiths Richard Ian

    5/8/25 7:08:00 AM ET
    $SLN
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $SLN alert in real time by email
    SEC FORM 4 SEC Form 4
    FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549

    STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

    Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
    or Section 30(h) of the Investment Company Act of 1940
    OMB APPROVAL
    OMB Number: 3235-0287
    Estimated average burden
    hours per response: 0.5
      
    Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
      
    Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
    1. Name and Address of Reporting Person*
    Griffiths Richard Ian

    (Last) (First) (Middle)
    FLOOR 1 LIBERATION STATION
    ESPLANADE

    (Street)
    ST HELIER Y9 JE2 3AS

    (City) (State) (Zip)
    2. Issuer Name and Ticker or Trading Symbol
    Silence Therapeutics plc [ SLN ]
    5. Relationship of Reporting Person(s) to Issuer
    (Check all applicable)
    Director X 10% Owner
    Officer (give title below) Other (specify below)
    3. Date of Earliest Transaction (Month/Day/Year)
    05/05/2025
    4. If Amendment, Date of Original Filed (Month/Day/Year)
    6. Individual or Joint/Group Filing (Check Applicable Line)
    X Form filed by One Reporting Person
    Form filed by More than One Reporting Person
    Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
    1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
    Code V Amount (A) or (D) Price
    Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
    (e.g., puts, calls, warrants, options, convertible securities)
    1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
    Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
    American Depositary Shares $3.94 05/05/2025 P 100,000 (1) (1) Ordinary Shares 300,000 (1) 10,820,853 D
    American Depositary Shares $3.96 05/06/2025 P 100,000 (1) (1) Ordinary Shares 300,000 (1) 10,920,850 D
    American Depositary Shares $3.81 05/07/2025 P 50,000 (1) (1) Ordinary Shares 150,000 (1) 10,970,853 D
    Explanation of Responses:
    1. Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.
    /s/ Richard Ian Griffiths 05/07/2025
    ** Signature of Reporting Person Date
    Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
    * If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
    ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
    Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
    Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
    Get the next $SLN alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $SLN

    DatePrice TargetRatingAnalyst
    2/11/2025$6.00Sell
    Goldman
    12/2/2024Outperform
    BMO Capital Markets
    9/3/2024$40.00Buy
    Jefferies
    1/31/2024$67.00Outperform
    BMO Capital Markets
    5/8/2023$20.00Overweight
    Morgan Stanley
    12/9/2022$18.00Equal-Weight
    Morgan Stanley
    3/31/2022$33.00Buy
    Chardan Capital Markets
    More analyst ratings

    $SLN
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Silence Therapeutics Reports First Quarter 2025 Financial Results and Recent Business Highlights

      Company further extends cash guidance into 2028 Silence Therapeutics plc, Nasdaq: SLN ("Silence" or "the Company"), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported its financial results for the first quarter ended March 31, 2025, and reviewed recent business highlights. "Silence delivered another strong quarter focused on clinical and operational execution," said Craig Tooman, President and Chief Executive Officer at Silence. "We remain focused on advancing enrollment into the SANRECO Phase 2 study of divesiran, a first-in-class siRNA program in PV, and continue to be on-track to complete enrollment by the end of this year. We are a

      5/8/25 8:00:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Silence Therapeutics Welcomes Tim McInerney to Board of Directors

      Mr. McInerney brings over 30 years of industry experience spanning senior executive, finance and capital advisory roles in the pharmaceutical and biotechnology sectors Silence Therapeutics plc, Nasdaq: SLN ("Silence" or "the Company"), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced the appointment of Tim McInerney to the Company's Board of Directors, effective immediately. Mr. McInerney will stand for re-appointment to the Silence Board at the Annual General Meeting ("AGM") in June 2025. "We are thrilled to welcome Tim to the Silence Board," said Iain Ross, Chairman of the Silence Board. "Tim is a seasoned executive and board memb

      5/6/25 7:45:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Silence Therapeutics to Webcast Presentation at the Leerink Partners Global Healthcare Conference

      Silence Therapeutics plc, Nasdaq: SLN ("Silence" or the "Company"), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that management will present a company overview at the Leerink Partners Global Healthcare Conference on Wednesday, March 12th at 1:00 p.m. ET. The live webcast can be accessed via the Investors section of the Silence website at www.silence-therapeutics.com. An archived replay of the webcast will be available following the conference. About Silence Therapeutics Silence Therapeutics is a global clinical-stage biotechnology company committed to transforming people's lives by silencing diseases through precision engineer

      3/5/25 8:00:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SLN
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • Amendment: SEC Form SC 13G/A filed by Silence Therapeutics Plc

      SC 13G/A - Silence Therapeutics plc (0001479615) (Subject)

      11/14/24 1:13:14 PM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Amendment: SEC Form SC 13G/A filed by Silence Therapeutics Plc

      SC 13G/A - Silence Therapeutics plc (0001479615) (Subject)

      11/14/24 9:44:01 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Amendment: SEC Form SC 13G/A filed by Silence Therapeutics Plc

      SC 13G/A - Silence Therapeutics plc (0001479615) (Subject)

      11/12/24 4:31:49 PM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SLN
    SEC Filings

    See more
    • SEC Form 10-Q filed by Silence Therapeutics Plc

      10-Q - Silence Therapeutics plc (0001479615) (Filer)

      5/8/25 8:35:12 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Silence Therapeutics Plc filed SEC Form 8-K: Results of Operations and Financial Condition

      8-K - Silence Therapeutics plc (0001479615) (Filer)

      5/8/25 8:10:25 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form PRE 14A filed by Silence Therapeutics Plc

      PRE 14A - Silence Therapeutics plc (0001479615) (Filer)

      5/6/25 8:06:29 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SLN
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • SEC Form 4 filed by Large owner Griffiths Richard Ian

      4 - Silence Therapeutics plc (0001479615) (Issuer)

      5/8/25 7:08:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Large owner Griffiths Richard Ian

      4 - Silence Therapeutics plc (0001479615) (Issuer)

      5/2/25 10:28:34 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Large owner Griffiths Richard Ian

      4 - Silence Therapeutics plc (0001479615) (Issuer)

      4/30/25 7:13:20 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SLN
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Goldman initiated coverage on Silence Therapeutics with a new price target

      Goldman initiated coverage of Silence Therapeutics with a rating of Sell and set a new price target of $6.00

      2/11/25 7:12:20 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • BMO Capital Markets reiterated coverage on Silence Therapeutics

      BMO Capital Markets reiterated coverage of Silence Therapeutics with a rating of Outperform

      12/2/24 10:09:42 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Jefferies initiated coverage on Silence Therapeutics with a new price target

      Jefferies initiated coverage of Silence Therapeutics with a rating of Buy and set a new price target of $40.00

      9/3/24 8:14:09 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SLN
    Leadership Updates

    Live Leadership Updates

    See more
    • Silence Therapeutics Welcomes Tim McInerney to Board of Directors

      Mr. McInerney brings over 30 years of industry experience spanning senior executive, finance and capital advisory roles in the pharmaceutical and biotechnology sectors Silence Therapeutics plc, Nasdaq: SLN ("Silence" or "the Company"), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced the appointment of Tim McInerney to the Company's Board of Directors, effective immediately. Mr. McInerney will stand for re-appointment to the Silence Board at the Annual General Meeting ("AGM") in June 2025. "We are thrilled to welcome Tim to the Silence Board," said Iain Ross, Chairman of the Silence Board. "Tim is a seasoned executive and board memb

      5/6/25 7:45:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Silence Therapeutics Announces Retirement of Alistair Gray from Board of Directors

      Silence Therapeutics plc (NASDAQ:SLN) ("Silence" or the "Company"), an experienced and innovative biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today announced that Alistair Gray, who has served as an independent member of Silence's Board of Directors (the "Board") since 2015, informed the Company that he will retire from the Board, effective May 1, 2024. Iain Ross, Silence's Chairman of the Board, commented, "Alistair has made significant contributions to the Board and the Company over the past nine years. During his time on the Board, the Company has transitioned into a global player focused on the developmen

      4/29/24 8:30:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Silence Therapeutics Appoints Dr. Steven Romano as Incoming Chief Medical Officer and Head of Research and Development

      Dr. Romano will succeed Dr. Giles Campion, CMO and Head of R&D, following his retirement by year-end Silence Therapeutics plc, Nasdaq: SLN ("Silence" or "the Company"), an experienced and innovative biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today announced the appointment of Steven Romano, MD, as incoming Chief Medical Officer and Head of Research and Development. Dr. Romano will join Silence on April 1, 2023, and work alongside Giles Campion, MD, current CMO and Head of R&D at Silence, to ensure an efficient and smooth transition for Dr. Campion's retirement by year-end. Dr. Romano has served as non-execut

      3/28/23 7:05:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $SLN
    Financials

    Live finance-specific insights

    See more
    • Silence Therapeutics Reports Full Year 2024 Financial Results and Provides Business Update

      The Company's cash guidance is now extended into 2027 Company to host conference call and webcast today at 8 a.m. EST / 1 p.m. GMT Silence Therapeutics plc, Nasdaq: SLN ("Silence" or "the Company"), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today reported its financial results for the full year ended December 31, 2024, and provided a business update. "2024 was marked by strong clinical execution and pipeline advancement, highlighting the broad potential of our mRNAi GOLD™ platform to silence disease causing genes," said Craig Tooman, President and CEO of Silence. "In 2025, we are prioritizing investment in programs targeting rare conditi

      2/27/25 7:30:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Silence Therapeutics to Report Fourth Quarter and Full Year 2024 Results on February 27, 2025

      Silence Therapeutics plc, Nasdaq: SLN ("Silence" or "the Company"), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that the Company will release its financial and business results for the fourth quarter and full year ended December 31, 2024, on Thursday, February 27, 2025. Management will host a conference call at 8:00 a.m. ET / 1:00 p.m. GMT that day to discuss the Company's financial results and provide a general business update. The conference call will be webcast live and available on the Investors section of the Silence website at www.silence-therapeutics.com. The webcast will also be archived on the Company's website. Deta

      2/13/25 8:00:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Silence Therapeutics Announces Positive Results from Ongoing SANRECO Phase 1 Study of Divesiran in Polycythemia Vera Patients

      Divesiran eliminated the need for phlebotomy in all well-controlled patients following infrequent dosing and was well tolerated Data support advancing divesiran into Phase 2 Company to host conference call today at 8:30am Eastern Time Silence Therapeutics plc ("Silence" or the "Company"), (NASDAQ:SLN), an experienced and innovative biotechnology company committed to transforming people's lives by silencing diseases through precision engineered medicines, today announced positive results from the ongoing SANRECO Phase 1 repeat dose study of divesiran (SLN124), a siRNA (short interfering RNA) targeting TMPRSS6, in patients with polycythemia vera (PV). "With today's very exciting PV da

      6/27/24 7:30:00 AM ET
      $SLN
      Biotechnology: Pharmaceutical Preparations
      Health Care