Up to 7,285,713 shares of Common Stock Underlying Pre-Funded Warrants
| | | | | 1 | | | |
| | | | | 2 | | | |
| | | | | 3 | | | |
| | | | | 4 | | | |
| | | | | 5 | | | |
| | | | | 6 | | | |
| | | | | 8 | | | |
| | | | | 9 | | | |
| | | | | 14 | | | |
| | | | | 16 | | | |
| | | | | 16 | | | |
| | | | | 16 | | | |
| | | | | 16 | | |
Name(1)
|
| |
Shares of Common
Stock Beneficially Owned Prior to this Offering |
| |
Shares of Common
Stock Offered(2) |
| |
Beneficial Ownership After
this Offering(4) |
| |||||||||||||||
|
Shares
|
| |
%(3)
|
| ||||||||||||||||||||
Entities affiliated with RTW Investments, LP(5)
|
| | | | 9,965,901 | | | | | | 5,714,285 | | | | | | 4,251,616 | | | | | | 7.74% | | |
Atlas Private Holdings (Cayman) Ltd.(6)
|
| | | | 1,571,428 | | | | | | 1,571,428 | | | | | | — | | | | | | — | | |
Alyeska Master Fund, LP(7)
|
| | | | 2,142,850 | | | | | | 1,142,850 | | | | | | 1,000,000 | | | | | | 1.79% | | |
Nantahala Capital Partners Limited(8)
|
| | | | 1,430,117 | | | | | | 404,670 | | | | | | 1,025,447 | | | | | | 1.85% | | |
NCP RFM LP(9)
|
| | | | 902,619 | | | | | | 111,066 | | | | | | 791,553 | | | | | | 1.43% | | |
Blackwell Partners LLC – Series A(10)
|
| | | | 2,958,544 | | | | | | 198,549 | | | | | | 2,759,995 | | | | | | 4.88% | | |
Entities affiliated with OrbiMed Advisors LLC(11)
|
| | | | 4,767,209 | | | | | | 571,428 | | | | | | 4,195,781 | | | | | | 7.45% | | |
Entities associated with BVF Partners L.P.(12)
|
| | | | 3,713,794 | | | | | | 71,428 | | | | | | 3,642,366 | | | | | | 6.34% | | |
CVI Investments, Inc.(13)
|
| | | | 855,491 | | | | | | 322,154 | | | | | | 533,337 | | | | | | 0.96% | | |
Entities associated with Empery Asset
Management, LP(14) |
| | | | 1,285,714 | | | | | | 285,714 | | | | | | 1,000,000 | | | | | | 1.79% | | |
Stonepine Capital, LP(15)
|
| | | | 2,232,047 | | | | | | 285,714 | | | | | | 1,946,333 | | | | | | 3.46% | | |
Octagon Investments Master Fund LP(16)
|
| | | | 1,755,714 | | | | | | 35,714 | | | | | | 1,720,000 | | | | | | 3.13% | | |
117 Kendrick Street, Suite 500
Needham, Massachusetts 02494
(781) 292-4279
email address: [email protected]