SECURITIES AND EXCHANGE COMMISSION
      Washington, D.C. 20549
     
    
    
    
    
      
        Report of Foreign Private Issuer
        Pursuant to Rule 13a-16 or 15d-16
        Under the Securities Exchange Act of 1934
       
     
    
    
      For the month of May 2025
     
    
    
      
        
          Commission File Number 001-38367
         
       
     
    
    
      
        SOL-GEL TECHNOLOGIES LTD.
        (Translation of registrant’s name into English)
       
     
    
    
      
        7 Golda Meir Street
        Ness Ziona 7403650, Israel
        (Address of principal executive offices)
       
      
        
           
          
          Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F. 
         
       
     
    
    
    
    Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule
      101(b)(1):  ☐
    
    
    Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule
      101(b)(7):  ☐
    
    INFORMATION CONTAINED IN THIS REPORT ON FORM 6-K
    
    
    On May 23, 2025, Sol-Gel Technologies Ltd. (the “Company”) issued a press release entitled “Sol-Gel Reports First Quarter 2025
      Results”.
    
    
    Attached hereto is the following exhibit:
    
    
    
     
    This Report is incorporated by
        reference into the Company’s registration statements on Form S-8 (Registration Nos. 333-223915,  333-270477 and  333-286820), and Form F-3 (Registration No  333-286822), to be a part thereof from the date on which this report is submitted, to the extent not superseded by documents or reports subsequently filed or furnished.
    
    
    
    
      Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this
        report to be signed on its behalf by the undersigned, thereunto duly authorized.
     
    
    
        
          |   | SOL-GEL TECHNOLOGIES LTD. | 
        
          |   |   |   | 
        
          | Date: May 23, 2025 | By: | /s/ Eyal Ben-Or | 
        
          |   |   | Eyal Ben-Or | 
        
          |   |   | Chief Financial Officer |