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    SEC Form DEFA14A filed by ATAI Life Sciences N.V.

    6/2/25 9:15:50 PM ET
    $ATAI
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ATAI alert in real time by email
    DEFA14A 1 ef20050097_formdefa14a.htm DEFA14A


    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, DC 20549



    SCHEDULE 14A
    Proxy Statement Pursuant to Section 14(a) of the
    Securities Exchange Act of 1934


    Filed by the Registrant ☒

    Filed by a party other than the Registrant ☐

    Check the appropriate box:

    ☐
    Preliminary Proxy Statement

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    Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

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    Definitive Proxy Statement

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    Definitive Additional Materials

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    Soliciting Material under § 240.14a-12

    ATAI LIFE SCIENCES N.V.
    (Name of Registrant as Specified In Its Charter)

    (Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

    Payment of Filing Fee (Check all boxes that apply):

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    Fee paid previously with preliminary materials

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    Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11



     June 2, 2025 
     

     Disclaimer  All references in this presentation to “we”, “us”, “our”, “ atai”, or the “Company” refer to ATAI Life Sciences N.V. and its consolidated subsidiaries, unless the context otherwise requires. This presentation contains forward-looking stateme nts within the meaning of the private Securiti es Litigation Reform Act of 1995. We intend such forward-looking statements to be covered under by the safe harbor provisions for forward- looking stateme nts contained in Secti on 27A of the Securiti es Act of 1933, as amended, and Section 21 E of the Securiti es Exchange Act of 1934, as amended.” All statements other than statements of historical facts contained in this prese ntation, including statem ents r egarding our future results of operations and financial position, industry dynamics, business strategy and plans, anticipated milestones and timelines for our non-clinical, pre-clinical studies and clinical trials and our objectives for future operations, are forward-looking statements. The se statem ents r epre sent our opinions, expectations, beliefs, intentions, esti mates or strategies regardi ng the future, which may not be reali zed. In some cases, you can identify forward-looking stateme nts by terms such as “may,” “will,” “should,” “expects,” “plans,” “anticipates,” “could,” “intends,” “targets,” “projects,” “contemplates,” “believes,” “estimates,” “predicts,” “potential” or “continue” or the negative of these term s or other similar expr essions that are intended to identify forward-looking stateme nts.  Forward-looking stateme nts are based largely on our current expe ctations and projections about future events and financial trend s that we believe may affect our financial condition, results of operations, business  strategy, short term and long-term business operations and objectives and financial needs. These forward-looking stateme nts are subject to a number of risks, uncertainties and assumptions, including without  limitation the important factors described in the section titled “Risk Factors” in our most recent Annual Report on Form 10 -K filed with the Securities and Exchange Commission (“SEC”), as updated by our  subseque nt filings with the SEC, that may cause our actual results, perfor mance or achieve ments to differ materially and adversely from those expressed or implied by the forward-looking stateme nts. Moreover,  we operate in a very competitive and rapidly changing environm ent. N ew risks emer ge from time to time. It is not possible for our management to predict all risks, nor can we assess the impact of all factors on our  business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from tho se contained in any forward-looking stateme nts we may make. In light of these risks,  uncertainties and assumptions, the forward-looking events and circumstances discussed in this presentation may not occur and actual results could differ materially and adversely from those anticipated or implied in the forward-looking stateme nts. We caution you therefor e against relying on these forward-looking stateme nts, and we qualify all of our forward-looking stateme nts by these cautionary statements.  The forward-looking statements included in this presentation are made only as of the date hereof. Although we believe that the expectations reflected in the forward-looking stateme nts are r easonable, we cannot  guarantee that the future r esults, levels of activity, performance or events and circumstances reflecte d in the forward-looking statements will be achieved or occur. Moreover, neither we nor our advisors nor any  other person assum es responsibili ty for the accuracy and completeness of the forward-looking statements. Neither we nor our advisors undertake any obligation to update any forward-looking stateme nts for any  reason after the date of this presentation to conform these statements to actual results or to changes in our expe ctations, except as may be requi red by law. You should read this presentation with the  understanding that our actual future results, levels of activity, performance and events and circumstances may be mater ially differe nt from what we expect.  Unless otherwise indicated, information contained in this presentation concerning our industry, competitive position and the markets in which we operate is based on information from independent industry and  rese arch organizations, other third-party sources and management esti mates. Manageme nt estimates are der ived from publicly available information released by indepe ndent industry analysts and other third-  party sources, as well as data from our internal research, and are based on assumptions made by us upon r evie wing such data, and our exper ience in, and knowledge of, such industry and markets, which we beli eve  to be reasonable. In addition, projections, assumptions and estimates of the future perfor mance of the industry in which we operate or of any individual competi tor and our future performance are necessarily  subject to uncertainty and risk due to a variety of factors, including those described above. These and other factors could c ause results to differ materially from those expresse d in the estim ates made by  independent parties and by us. Industry publications, research, surveys and studies generally state that the information they contain has been obtained from sources believed to be reliable , but that the accuracy  and complete ness of such information is not guaranteed. Forecasts and other forward-looking information obtained from these sources are subj ect to the same qualifications and uncertainties as the other forward-looking stateme nts in this presentation.  This pr esentation contains excer pts of testimonials from individuals who have been treate d with compounds or derivatives of t he compounds underlying our product candidates in the context of third-party studies or otherwise that are solely intended to be illustrative and not r epre sentative of the potential for beneficial results of such compounds. Our product candidates are in preclini cal or clinical stages of development and none of our product candidates have bee n approved by the FDA or any other regulator y agency.  When discussing patents in this presentation, “issued” is to be understood to mean one or more issued or granted claims in one or more country, and “pending” is understood to mean one or more claims pending in a patent application in one or more country. Patent protection is a highly fact-sensitive inquiry, varying from country-to-countr y, and provides for enforceable protecti on to the extent (a) covered by a given claim, and (b) issued in such country or countries. No generalized descriptions of patents made herein should be relied upon; rather, a detailed discussion of our intellectual property and related risk factors can be found in our most r ecently filed Annual Report on Form 10-K, available on the SEC’s website at www.sec.gov.  Any trademarks included herein are the proper ty of the owner s thereof and are used for refe rence purposes only. Such use shou ld not be construed as an endorsement of the products or ser vices of the Company.  2 
     

     3  Stronger together, atai life sciences and Beckley Psytech unlock value for  patients and shareholders  Experienced management team  Fully owned pipeline with first-in-class potential  Multiple near-term milestones  Commercially scalable psychedelic therapies  Strong IP portfolio  Long-term financial synergies  Focused pipeline of rapid-acting, accessible psychedelic therapies for mental health 
     

     1. Lock-up holders may not sell or transfer shares befor e the later of (a) 60 days following the public announcement of the Phase 2b study or (b) transaction closing (the “Lock-Up Period”). Upon the expiry of the Lock-Up  Peri od lock-up holders shall cease to be restricted at a rate of 1/12th of each lock-up holders’ securities per month. Refer to the stock purchase agreement for additional details.  4  atai-Beckley Business Combination Highlights  Consideration  BPL-003  Data  Transaction Closing and Conditions  Combined Company will be led by atai’s CEO Srinivas Rao and the executive team will be a combination of atai and Beckley management  The Combined Company board will include two nominations from Beckley Psytech shareholders  Management  & Board  atai’s Board recommendation is subject to the following BPL-003 Phase 2b success criteria:  Statistical significance achieved on the primary endpoint (MADRS) of the Phase 2b study of BPL-003 with a p<0.05  All-stock deal  Non-atai Beckley Psytech shareholders will receive ~105.0M newly issued shares of atai common stock (~31% of pro forma entity)  ELE-101 program will be carved out into a separate entity prior to deal close and distributed to Beckley shareholders (including atai) on a  pro rata basis  Closing expected 2H 2025, subject to atai shareholder approval  Beckley Psytech shareholders have voted in favour of the transaction and ~25% of atai’s common stock have entered into voting  agreements in support of the transaction  Non-atai Beckley Psytech shareholders and Apeiron have entered into lock-up agreements, restricting the sale or transfer of their shares in the combined company following the public announcement of the results of the Phase 2b study of BPL-0031  Less than 3 individual cases of drug related serious adverse events observed in the 8mg arm during the Phase 2b study  Less than a total of 6% drug related serious adverse events observed in the 12mg arm during the Phase 2b study 
     

     5  Anne Johnson, CPA  Chief Financial Officer  Rob Conley, M.D.  Chief Research & Development Officer  Gerd Kochendoerfer, Ph.D.  Chief Operating Officer  Experienced management team with deep CNS, psychedelic and drug  development expertise  Cosmo Feilding Mellen  Co-founder and  Chief Strategy Officer1  Glenn Short, Ph.D.  Chief Scientific Officer  Srinivas Rao, M.D., Ph.D.  Co-founder and  Chief Executive Officer  Kevin Craig, M.D.  Chief Medical Officer  1. Cosmo Feilding Mellen will be nominatedat deal close to be a member of the Combined Company’s Supervisory Board. He will be formally delegated to participate on  the Executive Management Team as Chief Strategy Officer. 
     

     Combined vision is being delivered through a pipeline of fully-owned psychedelic  development programs across a range of compounds and psychiatric indications  Abbreviations: DMT = Dimethyltryptamine; R-MDMA = R enantiomer of 3,4-Methylened ioxymethamphetamine  Programs  Primary Indication  Preclin  Phase 1  Phase 2  Phase 3  Treatment Resistant Depression (TRD)  Social Anxiety Disorder (SAD)  TRD  VLS-01  DMT  EMP-01  R-MDMA  BPL-003  Mebufotenin (5-MeO-DMT) benzoate  Post-merger Fully-Owned Programs  Undisclosed  Novel 5-HT2A Receptor Agonists  (inc. non-hallucinogenic neuroplastogens)  6 
     

     Fully funded through multiple near-term milestones  ACHIEVED AND ANTICIPATED UPCOMING MILESTONES1,2  Q2’25  Q1’25  Q3’25  Q4’25  Q1’26  Ph 2b (CIAS)  data  RL-007  Pro-cognitive  neuromodulator  Ph 2a (SAD)  initiation  Ph 2a (SAD)  data  EMP-01  R-MDMA  Ph 2 (TRD)  data  Ph 2 (TRD)  trial initiation  ✓  VLS-01  DMT  Ph 2b (TRD)  data  Ph 2a (TRD)  SSRI OL data  Ph 2a (AUD)  OL data  ✓  BPL-003  Mebufotenin benzoate  Programs  Abbreviations: OL = Open-lab el; TRD = Treatment Resistant Depression; SAD = Soci al Anxiety Disorder; AUD = Alcoh ol Use Disor der ; CIAS = Cognitive Impairment Asso ciated with Sch izophreni a  1. All timing provided is estimat ed; 2. Trial initiation d efined as central regulat ory and ethics appro val  7  ✓  ✓ 
     

     Market Opportunity and Unmet Need  INTERVENTIONAL PSYCHIATRY 
     

     Leading interventional psychiatry treatment, SPRAVATO® (esketamine) for  TRD, achieved blockbuster status in 2024 (>$1B) with ~86% of sales in the US  9  2-hour dosing protocol with established infrastructure  Patients monitored for at least 2 hours at each treatment session  Delivered intranasally under the supervision of a healthcare provider  >5,000 certified clinics1  ~40-50K US patients treated in 20242  Potential for many administrations per year  Weeks 1 to 4: twice per week  Weeks 5 to 8: once weekly  Week 9 and after: every two weeks or once weekly  https://ww w.spravato.com/sprav ato-av ailab le-treatment-centers/  Based on global annual sales and gross to net pricing assumptions  Johnson&J ohnson Q4 an d Full-Year 2024 Results: https://w ww.investor.jnj.com/ new s/news -details/2025/Johnson--Johnson-Repor ts-Q4-and-Full-Year-2024-Results/default.aspx  $198M  $328M  $589M  $929M  $100M  $148M  $0M  $250M  $500M  $750M  $1,000M  $1,250M  Spravato® –ReportedGlobal Annual Sales3 (2021-24)  $26M  2021 22 23 24  $46M  $224M  $374M  $689M  $1,077M  RestofWorld  US  SPRAVATO® interventional psychiatry treatment paradigm  J&J now highlights SPRAVATO® as a “key franchise” guiding  $3 billion to $3.5 billion in annual sales 
     

     DEVELOPED TO PROVIDE RAPID AND DURABLE EFFICACY WITH A SHORT TIME-IN-CLINIC  Novel psychedelic treatments 
     

     BPL-003 and VLS-01 are novel psychedelic candidates developed to optimize  patient access for TRD with a short time-in-clinic  Abbreviations: TRD = Treatment Resistant Depression; IND = Investigational New Drug Application; COM = Com position of Matter  1. Dourron HM, Nichols CD, Simonsson O, Bradley M, Carhart-Harris R, Hendricks PS. 5-MeO-DMT: An atypical psychedelic with unique pharma cology, phenomenology & risk? Psychopharma cology (Berl). 2023 Dec  TARGET POSITION  First-in-class and best-in-class for mebufotenin  First-in-class and best-in-class for DMT  PHARMACOLOGY  (5-HT2A : 5-HT1A  binding affinity1)  5-HT1A/5-HT2A receptor agonist  (1 : 0.009)  5-HT2A receptor agonist  (1 : 3.4)  FORMULATION  Dry Powder Nasal Spray (transmucosal)  Buccal Film (transmucosal)  TREATMENT DURATION  ~2 hours  ~2 hours  DEVELOPMENT STAGE  Phase 2b; topline data anticipated mid ’25  IND approved  Phase 2; topline data anticipated Q1 ’26  IND approved  INTELLECTUAL PROPERTY  US COM and Methods issued; additional pending  US COM and Methods issued; additional pending  VLS-01  Dimethyltryptamine  BPL-003  Mebufotenin benzoate  11 
     

     BPL-003 and VLS-01 designed to leverage SPRAVATO® 2-hour in-clinic  treatment paradigm in depression  12  0  4  8  12  ANTICIPATEDTIME TO DISCHARGE FROMCLINIC POST-DOSE 1  (inhours)Ilustrative  SPRAVATO® BPL-003  Multi-dose Psilocybin  5-MeO- +analogs  DMT  MDMA  LSD  Average workday (8hours)  ~2  ~2  ~2  ~1 to3*  ~6  ~8  ~8 to12  VLS-01  Subject to further validation through future clinical studies and real-world evidence  w ww.spravatohcp.com/#find-a-center  * If multi-dose required  KEY TAKEAWAYS  Predictable 2-hour treatment: the potential to fit into the  2-hour in-clinic treatment paradigm established by SPRAVATO  Potential extended durability reduces patient burden: 1-2 doses of a psychedelic therapy provides a sustained effect, simplifying the dosing schedule compared to SPRAVATO’s once-weekly regimen  Significantly improves use of infrastructure: lower dosing frequency compared to SPRAVATO could lower provider burden, and improve payer receptivity 
     

     INTRANASAL MEBUFOTENIN BENZOATE FOR TRD & AUD  BUSINESS COMBINATION WITH BECKLEY PSYTECH  BPL-003 
     

     BPL-003 Phase 1 Results  BPL-003 PHASE 1 RESULTS KEY TAKEAWAYS  30  25  20  15  10  5  0  0  2  4  6  8  10  PK/PD results demonstrated a dose proportional profile with perceptual  effects generally resolving <90 minutes  Pharmacokinetics (PK)  Exposure was dose-proportional  Rapid onset with mean Tmax of 6-17 min  Mean half life of 15-30 min  Pharmacodynamics (PD):  Participants were psychedelic naive  All participants on doses ≥6mg achieved  intensity scores ≥7  Perceptual effects generally fully resolved within <90 mins  12mg (n=5)  10mg (n=5) 8mg (n=5) 6mg (n=4) 4mg (n=4)  2.5mg (n=4)  1mg (n=4)  Mean plasma concentration  level (ng/ml)  Time post-dose (minutes) 60  0  12  30  Time post-dose (minutes) 60  90  Mean SDI (1 to 10)  0  12  30  90  Dose range taken forward to  Phase 2  BPL-003  Phase 1  PK Profile  BPL-003  Phase 1 Subjective Drug Intensity (SDI) Rating  12mg (n=5) 10mg (n=5) 8mg (n=5) 6mg (n=4)  14  PK: Pharmacokinetic 
     

     BPL-003  Completed Part 1 & Part 2 of the open-label Phase 2a study investigating BPL-  003 in patients with TRD  Phase 2a Clinical Trial Design  Key Inclusion Criteria:  Montgomery-Asberg Depression  Rating Scale (MADRS) score ≥24  Part 1 & 3: willing and able to discontinue current antidepressants  Part 2: on current stable dose of antidepressant SSRI therapy  Key Objectives: Primary Endpoint:  Safety and tolerability of  BPL-003  Other Secondary Endpoints:  MADRS change through  Week 12  Remission and response rates  through Week 12  Study Details:  Open-label study evaluating a single dose of BPL-003  nasal spray, in patients with moderate-to-severe TRD  Parts 1 & 3 are in patients not on anti-depressants, Part 2 is in patients who  are also taking select SSRIs to explore effects of co-administration  Psychological support during preparation, dosing and integration  S cr e e nin g  Par t 1 :  M on ot he r a py  O p e n l a b e l  Day 2  85  C omp le t e d Q 1 2 0 24  S i ngle do s e o f BPL- 00 3  29  Par t 2 :  Adj un ct to SS RIs  C omp le t e d Q 2 2 0 25  Par t 3:  Tw o- do se i ndu ct io n mo del  I ni t i at e d Q 3 2 02 4  15 
     

     BPL-003 Phase 2a Part 1 (Monotherapy Cohort) Data  MADRS SCORE OVER TIME BPL-003 10 MG SINGLE DOSE KEY TAKEAWAYS  Mean MADRS reduction of ~13 points at Day 2, and sustained  to Day 85  55% of patients met response criteria1 one day after a single  10mg dose of BPL-003  55% of patients met clinical remission criteria2 one month after a single dose  Improvements broadly sustained for 3 months after dosing with 45% of subjects meeting remission criteria at day 85  Patients were deemed ready for discharge within an average time of less than 2 hours  Rapid & durable clinical response and remission induced in over 50% of  patients following a single dose of BPL-003 monotherapy  Interim analysis of the per protocol population (n=11)  Response defined as ≥50% improvement in MADRS score  Remission defined as MADRS score ≤10  16 
     

     Initial data from the adjunctive/SSRI cohort is broadly consistent with monotherapy data  BPL-003 Phase 2a Part 2 (Adjunct to SSRIs) Initial Data  MADRS SCORE OVER TIME BPL-003 SINGLE DOSE (ADJUNCTIVE) KEY TAKEAWAYS  Participants with moderate-severe depression having failed 2  prior therapies and on a single SSRI  Mean MADRS reduction of 19 points at Day 29 with 18-point  reduction at Day 85  No new safety signal identified  Tolerability profile appears consistent with monotherapy dosing  17  Response defined as ≥50% improvement in MADRS score; Remission defined as MADRS score ≤10 
     

     Drug Related TEAEs  TOTALa  N subjects (%) [N events]b  Administration site discomfortc  10 (41.7%) [141#]  Nausea  5 (20.8%) [51#]  Vomiting  5 (20.8%) [55#]  Other events (<10% frequency)  8 (33.3%) [83#, 1*]  TOTAL  14 (58%) [32]  BPL-003 Phase 2a Part 1 & 2 Safety  DRUG RELATED TEAES KEY TAKEAWAYS  97% of events were mild or moderate and there were no Serious Adverse Events (SAEs)  ~90% of drug-related AEs occurred on the day of dosing, and all were resolved without intervention  AE profile of BPL-003 in TRD subjects is similar to that seen in healthy volunteers  In Phase 2a, BPL-003 was well-tolerated as monotherapy and adjunctive  treatment in TRD patients with transient events and no Serious AEs observed  Combined Drug Related TEAEs from Part 1 & 2 (n=24)  Events were mild unless labelled. #Moderate events. *Severe event  Administration site discomfort includes the preferred terms administration site irritation, administration site pain, administration site discharge, administration site erythema and nasal discomfort  TEAE =Treatment emergent adverse events  18 
     

     BPL-003  BPL-003 randomized, quadruple-masked, monotherapy Phase 2b study in  moderate to severe TRD patients  Phase 2b Clinical Trial Design  Key Inclusion Criteria:  Patients with moderate to severe TRD  Hamilton Depression Scale (HAM-D) >= 19   Willing and able to discontinue current antidepressants  Key Objectives:  PRIMARY ENDPOINT:   MADRS change from baseline at Week 4, 12mg vs. 0.3mg  OTHER SECONDARY ENDPOINTS:  Remission and responder rates  MADRS change from baseline at  Day 2, Week 1 & Week 8  MADRS change from baseline for 8mg vs 0.3mg  1. Patients entering the open-lab el extension are randomized to receive either a single 12mg dose or a biphasic 4mg and 8mg dose approximately 10 minutes apart.  Abbreviations: MADRS = Montgomery–Åsberg Depression Rating Scale; CGI-S = Clinica l Global Impressions-Severity ; PGIC = Patient's Glob al Impression of Change; EQ-5D = EuroQol-5D  19  TRIAL STATUS  En ro lmen t co mpl et ed  To pli ne data anti ci pated mi d - 2 02 5  Randomization (n=~196)  Day 0  Wk-8  Washout  12 mg1  Core Study  ( 8 weeks)  1st Primary Dose Analysis  57  Open Label Extension  ( 8 weeks)  1 2 8 29 57  1 2 29  2nd Dose  0. 3 mg  ( n=~7 0)  8 mg  ( n=~45)  12 mg  ( n=~7 0) 
     

     BPL-003  Strong IP portfolio with coverage out to 2043  20  BPL-003 has superior properties that are novel and non-obvious, compared to other salt forms  Higher permeation, less irritation, greater stability, dose-proportional PK  These novel and non-obvious properties have enabled us to build strong IP protection around BPL-003  Multiple composition of matter and methods of use (including in depression) patents granted in US, Europe & UK covering mebufotenin benzoate salt and the most stable polymorph thereof (2040/1 expiry)  A granted US composition of matter patent covering the formulation of BPL-003 intended for Phase 3 (earliest expiry 2043)  Additional patents covering composition of matter, methods of synthesis, methods of use, crystalline forms and formulations pending in US, Europe & RoW  Patent Term Extensions and Supplementary Protection Certificates will be sought, where available  Regulatory exclusivity provides additional protection  IP Overview 
     

     Summary + Q&A 
     

     Together, atai Life Sciences and Beckley Psytech will create impactful  psychedelic treatments addressing significant unmet needs in mental health  22  Short treatment time, patent-protected: BPL-003 potential to be a first-in- class mebufotenin benzoate therapy; and VLS-01, potential best-in-class route of administration and tolerability for DMT  1  Near-term catalysts: BPL-003 Phase 2b readout anticipated midyear,  additional Phase 2 data readouts anticipated over the next 12 months  2  Simplified & synergistic corporate structure: single public entity fully unlocks value of atai and Beckley Psytech’s teams and assets  3 
     

     23 
     

    Forward-looking Statements

    This communication contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. We intend such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in Section 27A of the Securities Act, and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). The words “believe,” “may,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “expect,” “anticipate,” “initiate,” “could,” “would,” “project,” “plan,” “potentially,” “preliminary,” “likely,” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these words. Forward-looking statements include express or implied statements relating to, among other things: expectations regarding the closing of the transaction, including timing and approvals; expectations regarding operations of the combined company, including strategic value of the clinical development programs for patients and shareholders as well as expectations regarding financial synergies; timing and results of Beckley’s BPL-003 Phase 2b trial and related data readouts; expectations regarding Beckley’s other clinical assets, including ELE-101; expectations regarding the concurrent private placement, including related closing conditions; our business strategy and plans; and the potential, success, cost and timing of development of our product candidates, and the product candidates of those companies we invest in.

    Forward-looking statements are neither promises nor guarantees, but involve known and unknown risks and uncertainties that could cause actual results to differ materially from those projected, including, without limitation, the important factors described in the section titled “Risk Factors” in our most recent Annual Report on Form 10-K filed with the SEC, as such factors may be updated from time to time in atai's other filings with the SEC. atai disclaims any obligation or undertaking to update or revise any forward-looking statements contained in this press release, other than to the extent required by applicable law.

    No Offer or Solicitation

    This communication is for information purposes only and is not intended to and does not constitute, or form part of, an offer, invitation or the solicitation of an offer or invitation to purchase, otherwise acquire, subscribe for, sell or otherwise dispose of any securities, or the solicitation of any vote or approval in any jurisdiction, pursuant to the proposed transaction or otherwise, nor shall there be any sale, issuance or transfer of securities in any jurisdiction in contravention of applicable law.

    Additional Information and Where to Find It

    This communication is being made in respect of the proposed transaction between the Company and Beckley Psytech Limited. In connection with the proposed transaction, the Company will file with the SEC a proxy statement on Schedule 14A (the “Proxy Statement”), as well as other relevant documents regarding the proposed transaction. This press release is not a substitute for the Proxy Statement or any other document which the Company may file with the SEC. INVESTORS ARE URGED TO READ IN THEIR ENTIRETY THE PROXY STATEMENT REGARDING THE TRANSACTION WHEN IT BECOMES AVAILABLE AND ANY OTHER RELEVANT DOCUMENTS FILED WITH THE SEC, AS WELL AS ANY AMENDMENTS OR SUPPLEMENTS TO THOSE DOCUMENTS, BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION.
     


    A free copy of the Proxy Statement, as well as other filings containing information about the Company, when such documents become available, may be obtained at the SEC’s website (http://www.sec.gov).

    Participants in the Solicitation

    The Company and its directors and executive officers may be deemed to be participants in the solicitation of proxies from its shareholders in respect of the proposed transactions contemplated by the Proxy Statement. Information regarding the persons who are, under the rules of the SEC, participants in the solicitation of the shareholders of the Company in connection with the proposed transactions, including a description of their direct or indirect interests, by security holdings or otherwise, will be set forth in the Proxy Statement when it is filed with the SEC. Information regarding the Company’s directors and executive officers is contained in its Annual Report on Form 10-K for the year ended December 31, 2024 and its Proxy Statement on Schedule 14A, dated April 21, 2025, which are filed with the SEC.



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    Recent Analyst Ratings for
    $ATAI

    DatePrice TargetRatingAnalyst
    4/4/2025Buy
    Berenberg
    11/18/2024$15.00 → $10.00Buy
    H.C. Wainwright
    4/3/2024$6.00Hold → Buy
    Maxim Group
    11/1/2022$18.00Buy
    Loop Capital
    11/30/2021$25.00Buy
    Maxim Group
    11/22/2021$40.00 → $50.00Buy
    HC Wainwright & Co.
    11/16/2021$25.00 → $24.00Outperform
    Credit Suisse
    11/16/2021$19.00 → $17.00Sector Perform
    RBC Capital
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    $ATAI
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

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    • Amendment: SEC Form SC 13D/A filed by ATAI Life Sciences N.V.

      SC 13D/A - ATAI Life Sciences N.V. (0001840904) (Filed by)

      9/27/24 7:56:26 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13D/A filed by ATAI Life Sciences N.V. (Amendment)

      SC 13D/A - ATAI Life Sciences N.V. (0001840904) (Filed by)

      5/3/24 4:06:02 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13D/A filed by ATAI Life Sciences N.V. (Amendment)

      SC 13D/A - ATAI Life Sciences N.V. (0001840904) (Filed by)

      3/12/24 9:30:31 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ATAI
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

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    • Berenberg initiated coverage on atai Life Sciences N.V.

      Berenberg initiated coverage of atai Life Sciences N.V. with a rating of Buy

      4/4/25 8:27:07 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • H.C. Wainwright reiterated coverage on atai Life Sciences N.V. with a new price target

      H.C. Wainwright reiterated coverage of atai Life Sciences N.V. with a rating of Buy and set a new price target of $10.00 from $15.00 previously

      11/18/24 11:31:29 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • atai Life Sciences N.V. upgraded by Maxim Group with a new price target

      Maxim Group upgraded atai Life Sciences N.V. from Hold to Buy and set a new price target of $6.00

      4/3/24 8:14:20 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ATAI
    SEC Filings

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    • SEC Form DEFA14A filed by ATAI Life Sciences N.V.

      DEFA14A - ATAI Life Sciences N.V. (0001840904) (Filer)

      6/2/25 9:15:50 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEFA14A filed by ATAI Life Sciences N.V.

      DEFA14A - ATAI Life Sciences N.V. (0001840904) (Filer)

      6/2/25 5:17:11 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form DEFA14A filed by ATAI Life Sciences N.V.

      DEFA14A - ATAI Life Sciences N.V. (0001840904) (Filer)

      6/2/25 4:38:39 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ATAI
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

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    • Large owner Apeiron Investment Group Ltd. bought $2,520,000 worth of shares (1,800,000 units at $1.40) (SEC Form 4)

      4 - ATAI Life Sciences N.V. (0001840904) (Issuer)

      3/24/25 5:00:18 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Large owner Apeiron Investment Group Ltd. bought $22,755,008 worth of shares (10,835,718 units at $2.10) (SEC Form 4)

      4 - ATAI Life Sciences N.V. (0001840904) (Issuer)

      2/19/25 6:00:05 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Brand Florian bought $23,120 worth of shares (20,000 units at $1.16), increasing direct ownership by 18% to 130,000 units (SEC Form 4)

      4 - ATAI Life Sciences N.V. (0001840904) (Issuer)

      11/20/23 9:17:41 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ATAI
    Financials

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    $ATAI
    Press Releases

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    $ATAI
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

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    • atai Life Sciences and Beckley Psytech to Combine Creating a Global Leader in Psychedelic Mental Health Therapies

      Strategic combination establishes a market-leading mental health company with a pipeline that includes potentially transformative, rapid-acting psychedelic assets differentiated by their convenient route of administration and short time-in-clinicCombined company will operate under the name atai Beckley with a joint leadership team and Board that leverage the deep psychedelic, drug development and CNS expertise within both organizationsTopline data from the Phase 2b study of BPL-003 in patients with treatment-resistant depression (TRD) is expected in mid-2025 - the largest controlled trial of mebufotenin (5-MeO-DMT) and the first and only controlled trial to investigate mebufotenin in the U.S

      6/2/25 6:00:00 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • atai Life Sciences Announces Strategic Investment in Beckley Psytech to Accelerate the Clinical Development of Short-Duration Psychedelics

      Strategic investment in Beckley Psytech reinforces atai's position as the biopharmaceutical company with the largest and most diverse portfolio of clinical-stage psychedelic candidatesTwo patent-protected, clinical-stage programs BPL-003 (intranasal 5-MeO-DMT) and ELE-101 (intravenous psilocin) complement atai's existing drug development programs Multiple clinical readouts anticipated from this investment in Beckley Psytech within next 12 months, including a Phase 2b readout of BPL-003 in Treatment Resistant Depression in 2H24 BPL-003 has the potential to become a first-in-class short-duration psychedelic treatment with rapid acting and durable antidepressant effects Anticipated synergies th

      1/4/24 7:00:00 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • atai Life Sciences Announces Fourth Quarter and Full Year 2021 Financial Results, Reports on R&D Progress and Highlights Strategic Focus Areas of its Innovative Mental Health Platform

      –   Highlights included positive Phase 2b data with COMP360 from a ground-breaking treatment resistant depression (TRD) trial, highly encouraging Phase 2a proof-of-mechanism data with RL-007 in cognitive impairment associated with schizophrenia (CIAS), clinical trial initiations with PCN-101, GRX-917 and DMX-1002, and successful completion of 2 cohorts in the Introspect Digital Therapeutics ketamine trials –   Eight new programs added to platform since January 2021 bringing total, as of today, to 13 discovery and drug development programs and four enabling technologies –   Ended 2021 very well capitalized with $362 million to execute our strategy to achieve clinically meaningful and sustai

      3/30/22 6:59:00 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • atai Life Sciences and Beckley Psytech to Combine Creating a Global Leader in Psychedelic Mental Health Therapies

      Strategic combination establishes a market-leading mental health company with a pipeline that includes potentially transformative, rapid-acting psychedelic assets differentiated by their convenient route of administration and short time-in-clinicCombined company will operate under the name atai Beckley with a joint leadership team and Board that leverage the deep psychedelic, drug development and CNS expertise within both organizationsTopline data from the Phase 2b study of BPL-003 in patients with treatment-resistant depression (TRD) is expected in mid-2025 - the largest controlled trial of mebufotenin (5-MeO-DMT) and the first and only controlled trial to investigate mebufotenin in the U.S

      6/2/25 6:00:00 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • atai Life Sciences to Participate in Upcoming Investor Conferences

      NEW YORK and BERLIN, May 29, 2025 (GLOBE NEWSWIRE) -- atai Life Sciences  (NASDAQ:ATAI) ("atai" or "Company"), a clinical-stage biopharmaceutical company on a mission to develop highly effective mental health treatments to transform patient outcomes, today announced that the Company's management team is scheduled to participate in the following investor conferences in June: Jefferies Global Healthcare Conference Format: Fireside ChatDate and Time: Thursday, June 5 at 9:55 A.M. EDTLocation: New YorkWebcast link: here H.C. Wainwright 6th Annual Neuro Perspectives Hybrid Conference Format: Pre-recorded Fireside ChatDate and Time: Tuesday, June 17 at 7:00 A.M. EDTLocation: VirtualWebcast l

      5/29/25 8:30:00 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • atai Life Sciences Announces Positive Topline Data from Part 2 of Beckley Psytech's Phase 2a Study of BPL-003 in Combination with SSRIs for Treatment-Resistant Depression

      - Positive results show that a single dose of BPL-003, administered adjunctively to SSRIs, produced a rapid and durable antidepressant effect for up to three months after dosing - BPL-003 was well-tolerated and patients were able to be discharged within an average time of less than two hours after dosing - Data from the eight-week core, randomized stage of Beckley Psytech's Phase 2b study of BPL-003 for treatment-resistant depression is expected in mid-2025 NEW YORK and BERLIN, May 20, 2025 (GLOBE NEWSWIRE) -- atai Life Sciences (NASDAQ:ATAI) ("atai" or "Company"), a clinical-stage biopharmaceutical company on a mission to develop highly effective mental health treatments to transform p

      5/20/25 7:00:00 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 4 filed by Director Angermayer Christian

      4 - ATAI Life Sciences N.V. (0001840904) (Issuer)

      6/4/25 4:38:51 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 3 filed by new insider Hoffman John Francis

      3 - ATAI Life Sciences N.V. (0001840904) (Issuer)

      5/23/25 4:15:32 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Scientific Officer Short Glenn Frank sold $17,767 worth of shares (13,161 units at $1.35), decreasing direct ownership by 24% to 42,333 units (SEC Form 4)

      4 - ATAI Life Sciences N.V. (0001840904) (Issuer)

      3/24/25 9:00:05 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ATAI
    Leadership Updates

    Live Leadership Updates

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    • atai Life Sciences Announces Key Leadership Appointments as it Advances its Pipeline of Novel Psychedelic Therapeutics for Mental Health

      - Srinivas Rao M.D., Ph.D. succeeds as sole Chief Executive Officer- Kevin Craig, M.D. promoted to Chief Medical Officer- Glenn Short, Ph.D. promoted to Chief Scientific Officer- Gerd Kochendoerfer, Ph.D. joins as Chief Operating Officer NEW YORK and BERLIN, Jan. 10, 2025 (GLOBE NEWSWIRE) -- atai Life Sciences (NASDAQ:ATAI) ("atai" or "Company"), a clinical-stage biopharmaceutical company aiming to transform the treatment of mental health disorders, today announced key leadership appointments to advance its goal of delivering novel mental health therapeutics. Srinivas Rao M.D., Ph.D., has assumed the role of sole Chief Executive Officer (CEO), joined by the promotions of Kevin Craig, M.D.

      1/10/25 7:00:00 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • atai Life Sciences Strengthens Board with Appointment of Two New Independent Directors

      NEW YORK and BERLIN, May 23, 2024 (GLOBE NEWSWIRE) -- atai Life Sciences (NASDAQ:ATAI) ("atai" or "Company"), a clinical-stage biopharmaceutical company aiming to transform the treatment of mental health disorders, today announced the appointment of Scott Braunstein, M.D., and Laurent Fischer, M.D., as independent directors of atai's supervisory board ("Board") subject to applicable legal requirements. Scott Braunstein, M.D., is the Chief Executive Officer ("CEO") and Chairman of Marinus Pharmaceuticals, Inc. He is an operating partner at Aisling Capital and serves on the Board of Directors at both Caribou Biosciences, Inc. and Trevena Inc. Previously, Dr. Braunstein was Chief Operati

      5/23/24 7:00:00 AM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • atai Life Sciences Appoints Anne Johnson as Chief Financial Officer

      NEW YORK and BERLIN, Feb. 06, 2024 (GLOBE NEWSWIRE) -- atai Life Sciences (NASDAQ:ATAI) ("atai" or "Company") today announced that Anne Johnson, the Company's interim Chief Financial Officer since October 2023 and Chief Accounting Officer since August 2022, has been named Chief Financial Officer (CFO). Anne succeeds Stephen Bardin as the Company's CFO while Stephen will continue in an advisory role until March 31, 2024 to support the transition. "Anne has been an integral member of our team for over three years and has demonstrated the executive leadership, financial acumen, and track record to lead our financial organization with excellence," said atai Co-founder and Chief Executive Off

      2/6/24 5:00:31 PM ET
      $ATAI
      Biotechnology: Pharmaceutical Preparations
      Health Care