UNITED STATES
        SECURITIES AND EXCHANGE COMMISSION
        Washington, D.C. 20549
         
        
        
          
         
        
        FORM 8-K
         
        
        
          
         
        
        Current Report Pursuant
        to Section 13 or 15(d) of the
        Securities Exchange Act of 1934
        
        
        Date of Report (Date of earliest event reported) November 3, 2025
         
        
        
          
         
        
        HOLOGIC, INC.
        
        (Exact Name of Registrant as Specified in Its Charter)
         
        
        
          
         
        
        DELAWARE
        
        (State or Other Jurisdiction of Incorporation)
        
        
        
            
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                 001-36214 
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                 04-2902449 
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                 (Commission File Number) 
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                 (I.R.S. Employer Identification No.) 
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                 250 Campus Drive, Marlborough, Massachusetts 
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                 01752 
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                 (Address of Principal Executive Offices) 
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                 (Zip Code) 
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        (508) 263-2900
        (Registrant’s Telephone Number, Including Area Code)
        
        
        (Former Name or Former Address, if Changed Since Last Report)
         
        
        
          
         
        
        Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the
          following provisions:
        
        
        
            
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                 Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) 
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                 Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) 
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                 Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) 
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                 Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) 
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        Securities registered pursuant to Section 12(b) of the Act:
        
        
        
            
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                 Title of each class 
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                 Trading Symbol(s) 
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                 Name of each exchange on which registered 
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                 Common Stock, $.01 par value 
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                 HOLX 
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                 The Nasdaq Stock Market LLC 
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        Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this
          chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
        
        
        Emerging growth company ☐
        
        
        If an emerging growth company, indicate by check mark if the registrant has elected not
            to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
        
        
        
          
        
        Item 2.02  Results of Operations and Financial Condition.
        
        
        On November 3, 2025, Hologic, Inc. (“Hologic”) issued a press release announcing its financial results for the fourth quarter ended
          September 27, 2025. A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein in its entirety by reference.
        
        
        Limitation on
            Incorporation by Reference. The information furnished in this Item 2.02, including the press release attached hereto as Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as
          amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall such information be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act except as set
          forth by specific reference in such a filing.
        
        
        Cautionary Note Regarding
            Forward-Looking Statements. Except for historical information contained in the press release attached as an exhibit hereto, the press release contains forward-looking statements that involve certain risks and uncertainties that could
          cause actual results to differ materially from those expressed or implied by these statements. Please refer to the cautionary note in the press release regarding these forward-looking statements.
        
        
        Additional Information and Where to Find It
        
        
        In connection with the proposed acquisition of Hologic by affiliates of Blackstone Inc. and TPG Capital, Hologic will file with
          the SEC a Proxy Statement of Hologic (the “Proxy Statement”). Hologic plans to mail to its stockholders a definitive Proxy Statement in connection with the proposed transaction. HOLOGIC URGES YOU TO READ THE PROXY STATEMENT AND OTHER RELEVANT
          DOCUMENTS FILED OR TO BE FILED WITH THE SEC CAREFULLY AS THEY BECOME AVAILABLE, AS WELL AS ANY AMENDMENTS OR SUPPLEMENTS TO THESE DOCUMENTS, BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION ABOUT HOLOGIC, BLACKSTONE INC., TPG CAPITAL, THE PROPOSED
          TRANSACTION AND RELATED MATTERS. You will be able to obtain a free copy of the Proxy Statement and other related documents (when available) filed by Hologic with the SEC at the website maintained by the SEC at www.sec.gov. You also will be able
          to obtain a free copy of the Proxy Statement and other documents (when available) filed by Hologic with the SEC by accessing the investor relations section of Hologic’s website at https://investors.hologic.com or by contacting Hologic investor
          relations at 
[email protected] or calling 858-410-8904.
 
        
        
        Participants in the Solicitation
        
        
        Hologic and its directors and executive officers may be deemed to be participants in the solicitation of proxies from Hologic
          stockholders in connection with the proposed transaction. Information regarding the directors and executive officers of Hologic, including a description of their direct or indirect interests, by security holdings or otherwise, is set forth (i) in
          Hologic’s definitive proxy statement for its 2025 Annual Meeting of Stockholders, including under the headings “Proposal No. 1 – Election of Directors,” “Executive Officers,” “Compensation Discussion and Analysis,” “Executive Compensation
          Tables,” “Securities Ownership by Directors and Executive Officers” and “Certain Relationships and Related-Party Transactions,” which was filed with the SEC on January 16, 2025 and is available at
          https://www.sec.gov/ix?doc=/Archives/edgar/data/859737/000114036125001287/ny20038205x1_def14a.htm, and (ii) to the extent holdings of Hologic’s securities by its directors or executive officers have changed since the amounts set forth in
          Hologic’s definitive proxy statement for its 2025 Annual Meeting of Stockholders, such changes have been or will be reflected on Initial Statement of Beneficial Ownership of Securities on Form 3, Statement of Changes in Beneficial Ownership on
          Form 4, or Annual Statement of Changes in Beneficial Ownership on Form 5 filed with the SEC, which are available at EDGAR Search Results https://www.sec.gov/edgar/browse/?CIK=0000859737&owner=only.
        
        
        
        Other information regarding the participants in the proxy solicitation and a description of their direct and indirect interests,
          by security holdings or otherwise, will be contained in the proxy statement and other relevant materials to be filed with the SEC when they become available. You may obtain free copies of these documents as described above.
        
        
        Item 9.01  Financial Statements and Exhibits.
        
        
        (d) Exhibits.
        
        
        
          
              
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                   Exhibit 
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                   Description 
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                   Press release dated November 3, 2025, of Hologic, Inc. announcing its financial results for the fourth quarter ended September 27, 2025. 
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                   104 
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                   Cover Page Interactive Data File - the cover page XBRL tags are embedded within the Inline XBRL document. 
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        SIGNATURES
        
        
        Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its
          behalf by the undersigned hereunto duly authorized.
        
        
        
            
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                 Date: November 3, 2025 
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                 HOLOGIC, INC. 
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                 By: 
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                 /s/ Karleen M. Oberton 
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                 Karleen M. Oberton 
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                 Chief Financial Officer 
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