SEC Form DEFA14A filed by Pacira BioSciences Inc.

Get informed before you vote *If you choose to vote these shares in person at the meeting, you must request a “legal proxy.” To do so, please follow the instructions at www.ProxyVote.com or request a paper copy of the materials, which will contain the appropriate instructions. Please check the meeting materials for any special requirements for meeting attendance. Smartphone users Point your camera here and vote without entering a control number Your Vote Counts! FLASHID-JOB# For complete information and to vote, visit www.ProxyVote.com Control # Ricky Campana P.O. Box 123456 Suite 500 51 Mercedes Way Edgewood, NY 11717 148,294 322,224 1 OF 2 30# Hextone, Inc. P.O. Box 9142 Farmingdale, NY 11735 XXXX XXXX XXXX XXXX PACIRA BIOSCIENCES, INC. 2025 Annual Meeting Vote by June 09, 2025 11:59 PM ET You invested in PACIRA BIOSCIENCES, INC. and it's time to vote! You have the right to vote on proposals being presented at the Annual Meeting. This is an important notice regarding the availability of proxy material for the shareholder meeting to be held on June 10, 2025. View the Notice & Proxy Statement, Annual Report online OR you can receive a free paper or email copy of the material(s) by requesting prior to May 27, 2025. If you would like to request a copy of the material(s) for this and/or future shareholder meetings, you may (1) visit www.ProxyVote.com, (2) call 1-800-579-1639 or (3) send an email to [email protected]. If sending an email, please include your control number (indicated below) in the subject line. Unless requested, you will not otherwise receive a paper or email copy. Vote in Person at the Meeting* June 10, 2025 1:30 PM EDT 5 Sylvan Way, Suite 300 Parsippany, NJ 07054 Vote in Person or Virtually at the Meeting: www.cesonlineservices.com/pcrx25_vm

Voting Items Board Recommends THIS IS NOT A VOTABLE BALLOT This is an overview of the proposals being presented at the upcoming shareholder meeting. Please follow the instructions on the reverse side to vote these important matters. Vote at www.ProxyVote.com FLASHID-JOB# Control # XXXX XXXX XXXX XXXX 1.00000 322,224 148,294 Under New York Stock Exchange rules, brokers may vote “routine” matters at their discretion if your voting instructions are not communicated to us at least 10 days before the meeting. We will nevertheless follow your instructions, even if the broker’s discretionary vote has already been given, provided your instructions are received prior to the meeting date. PACIRA BIOSCIENCES, INC. 2025 Annual Meeting Vote by June 09, 2025 11:59 PM ET 1. Election of Directors Nominees: 01 Marcelo Bigal 02 Frank D. Lee 03 Alethia Young For 2 Ratification of the appointment of KPMG LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2025. For 3 Approval, on an advisory basis, of the compensation of our named executive officers. For 4 Advisory vote to approve the frequency of future advisory votes to approve the compensation of our named executive officers. Year 5 Approval of our Amended and Restated 2011 Stock Incentive Plan. For NOTE: Such other business as may properly come before the meeting or any adjournment thereof.