SEC Form DEFA14A filed by PepGen Inc.

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

(Rule 14a-101)

INFORMATION REQUIRED IN PROXY STATEMENT

SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐

Check the appropriate box:

PEPGEN INC.

(Exact name of registrant as specified in its charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check all boxes that apply):

Logo PepGen TM C/OTABULATOR,P.O.BOX 80l6,CARY, NC27512-9903 Your vote matters! PepGen Inc. Annual Meeting of Stockholders Wednesday, June 4, 2025 12:00 PM, Eastern Day1ight Time Annual meeting to be held virtually via the internet – please visit \WWW.proxydocs.com/PEPG for more details. You must register to attend or participate in the annual meeting online at www.proxydocs.com/PEPGprior to the commencement of the annual meeting. For a convenient way to view proxy materials, VOTE. and obtain directions to attend the meeting go to www.proxydocs.com/PEPG To vote your proxy while visiting this site, you will need the 12 digit control number in the box below. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. This is not a ballot. You cannot use this notice to vote your shares, We encourage you to access and review all of the important information contained in the proxy materials available on the Internet or by mail before voting. Under United States Securities and Exchange Commission rules, proxy materials do not have to be delivered in paper. Proxy materials can be distributed by making them available on the Internet. If You want to receive a paper or e-mail copy of the proxy materials, you must request one. There is no charge to you for requesting a copy. In order to receive a paper package in time for this year’s meeting, you must make this request on or before May 23, 2025. SEEREVERSE FOR FULL AGENDA Meeting Materials: Notice of Meeting and Proxy Statement & Annual Report on Form 10-K Important Notice Regarding the Availability of Proxy Materials for the Stockholders Meeting to be Held on June 4, 2025 For Stockholders of record as of April 8, 2025 To order paper materials, use one of the following methods. Internet: www.investorelections.com/PEPG Call: 1-866-648-8133 Email: [email protected]* If requesting material by e-mail, please send s blank e-mail with the 12 digit controlnumber (located above) in the subject line. No other requests, instructions or other in queries should be included with your e-mail requesting material.your control number Have the 12 digit control number located in the box above available when you access the website and follow the instructions. Copyright C 2025 BetaNXT, Inc. or its affiliates. All Rights Reserved

Logo PepGen TM PepGen Inc. Annual Meeting of Stockholders THE BOARD OF DIRECTORS RECOMMENDS A VOTE: FOR ON PROPOSALS 1 AND 2 PROPOSAL 1. To elect three Class III directors to our board of directors, to serve until the 2028 annual meeting of stockholders and until his or her successor has been duly elected and qualified, or until his or her earlier death, resignation or removal. 1 .01 Mitchell. Finer 1.02 Heidi Henson 1.03 Laurie B. Keating 2. To ratfy the appointment of KPMG LLP as our independent registered public accounting firm for the fiscal year ending December 31. 2025. To transact any other business property brought before the Annual Meeting or any adjournment or postponement of the Annual Meeting. Note: such other matters that may property come before the meeting or any adjournment or any postponement thereof will be voted by the persons named as proxies in their discretion.