• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • AI SuperconnectorNEW
  • Settings
  • RSS Feeds
PublishGo to AppAI Superconnector
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlertsPublish with Us
    Company
    AboutQuantisnow PlusContactJobsAI superconnector for talent & startupsNEW
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form S-8 filed by Seres Therapeutics Inc.

    5/7/25 4:06:14 PM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $MCRB alert in real time by email
    S-8 1 d911306ds8.htm S-8 S-8

    As filed with the Securities and Exchange Commission on May 7, 2025

    Registration No. 333-   

     

     
     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    FORM S-8

    REGISTRATION STATEMENT

    UNDER

    THE SECURITIES ACT OF 1933

     

     

    SERES THERAPEUTICS, INC.

    (Exact Name of Registrant as Specified in Its Charter)

     

     

     

    Delaware   27-4326290

    (State or other jurisdiction of

    incorporation or organization)

     

    (I.R.S. Employer

    Identification No.)

    101 Cambridgepark Drive

    Cambridge, MA 02140

    (Address of Principal Executive Offices) (Zip Code)

    Seres Therapeutics, Inc. 2025 Incentive Award Plan

    (Full Title of the Plan)

    Eric D. Shaff.

    President and Chief Executive Officer

    Seres Therapeutics, Inc.

    101 Cambridgepark Drive

    Cambridge, MA 02140

    (Name and Address of Agent for Service)

    (617) 945-9626

    (Telephone Number, including Area Code, of Agent for Service)

     

     

    Copies to:

    Peter N. Handrinos, Esq.

    Latham & Watkins LLP

    200 Clarendon Street

    Boston, MA 02116

    (617) 948-6060

     

     

    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

     

    Large accelerated filer   ☐    Accelerated filer   ☒
    Non-accelerated filer   ☐    Smaller reporting company   ☒
         Emerging growth company   ☐

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

     

     
     


    EXPLANATORY NOTE

    This Registration Statement on Form S-8 is being filed for the purpose of registering 479,750 shares of the Registrant’s common stock to be issued pursuant to the Seres Therapeutics, Inc. 2025 Incentive Award Plan (the “2025 Plan”). On April 10, 2025, the Registrant’s stockholders approved the amendment and restatement of the Seres Therapeutics, Inc. 2015 Incentive Award Plan (the “2015 Plan”) to, among other things, authorize the issuance of 2,230,243 shares of the Registrant’s common stock for awards under the amended and restated 2015 Plan, which includes 1,750,493 shares previously authorized for issuance under the 2015 Plan plus an increase of 479,750 shares, and extend the term of the amended and restated 2015 Plan to March 3, 2035. In connection with amending and restating the 2015 Plan, the name of the 2015 Plan was updated to the 2025 Plan.

    INCORPORATION BY REFERENCE OF CONTENTS OF

    REGISTRATION STATEMENTS ON FORM S-8

    The contents of the Registration Statements on Form S-8 (File Nos. 333-205253, 333-210171, 333-223514, 333-230092, 333-236824, 333-253776, 333-263134, 333-270319, 333-277658 and 333-285769), including any amendments thereto, filed with the Securities and Exchange Commission, relating to the 2025 Plan (as an amendment and restatement of the 2015 Plan), are incorporated by reference herein.

     

    Item 8.

    Exhibits.

     

    Number    Description
      4.1    Restated Certificate of Incorporation of the Registrant (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-37456) filed on July 1, 2015)
      4.2    Certificate of Amendment to Restated Certificate of Incorporation of the Registrant, dated June  27, 2023 (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-37456) filed on June 28, 2023)
      4.3    Certificate of Amendment to Restated Certificate of Incorporation of the Registrant, dated April  5, 2024 (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-37456) filed on April 8, 2024)
      4.4    Certificate of Amendment to Restated Certificate of Incorporation of Seres Therapeutics, Inc., dated April  21, 2025 (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-37456) filed on April 21, 2025)
      4.4    Amended and Restated By-Laws of the Registrant (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-37456) filed on January 2, 2024)
      5.1+    Opinion of Latham & Watkins LLP, counsel to the Registrant
     23.1+    Consent of PricewaterhouseCoopers LLP, Independent Registered Public Accounting Firm
     23.2+    Consent of Latham & Watkins LLP (included in Exhibit 5.1)
     24.1+    Power of attorney (included on signature pages below)
     99.1    Seres Therapeutics, Inc. 2025 Incentive Award Plan (incorporated by reference to Exhibit 10.1 to the Registrant’s Current Report on Form 8-K (File No. 001-37456) filed on April 14, 2025)
    107+    Filing Fee Table

     

    +

    Filed herewith


    SIGNATURES

    Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Cambridge, Commonwealth of Massachusetts, on this 7th day of May, 2025.

     

    SERES THERAPEUTICS, INC.
    By:   /s/ Eric D. Shaff
      Eric D. Shaff
      President and Chief Executive Officer

    POWER OF ATTORNEY

    KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Eric D. Shaff and Marella Thorell, or either of them, as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to file and sign any and all amendments, including post-effective amendments, to this registration statement, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or their substitute or substitutes may lawfully do or cause to be done by virtue hereof. This power of attorney shall be governed by and construed with the laws of the State of Delaware and applicable federal securities laws.

    Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed by the following persons in the capacities and on the dates indicated.

     

    SIGNATURE    TITLE   DATE

    /s/ Eric D. Shaff

    Eric D. Shaff

      

    President, Chief Executive Officer, Director

    (principal executive officer)

      May 7, 2025

    /s/ Marella Thorell

    Marella Thorell

      

    Executive Vice President and Chief Financial Officer

    (principal accounting officer and principal financial officer)

      May 7, 2025

    /s/ Stephen Berenson

    Stephen Berenson

       Chairman of the Board   May 7, 2025

    /s/ Dennis Ausiello

    Dennis Ausiello, M.D.

       Director   May 7, 2025

    /s/ Paul R. Biondi

    Paul R. Biondi

       Director   May 7, 2025

    /s/ Willard H. Dere

    Willard H. Dere, M.D.

       Director   May 7, 2025


    /s/ Claire M. Fraser

    Claire M. Fraser, Ph.D.

       Director   May 7, 2025

    /s/ Kurt C. Graves

    Kurt C. Graves

       Director   May 7, 2025

    /s/ Richard N. Kender

    Richard N. Kender

       Director   May 7, 2025

    /s/ Hans-Juergen Woerle

    Hans-Juergen Woerle

       Director   May 7, 2025
    Get the next $MCRB alert in real time by email

    Crush Q3 2025 with the Best AI Superconnector

    Stay ahead of the competition with Standout.work - your AI-powered talent-to-startup matching platform.

    AI-Powered Inbox
    Context-aware email replies
    Strategic Decision Support
    Get Started with Standout.work

    Recent Analyst Ratings for
    $MCRB

    DatePrice TargetRatingAnalyst
    5/8/2025$6.00Buy → Neutral
    Chardan Capital Markets
    10/24/2024Neutral → Underweight
    JP Morgan
    6/26/2023$12.00Outperform
    Oppenheimer
    4/21/2023$7.00Neutral
    JP Morgan
    7/23/2021$42.00 → $29.00Buy
    Canaccord Genuity
    7/23/2021$30.00 → $16.00Buy
    Chardan Capital
    7/23/2021$36.00 → $18.00Outperform
    Oppenheimer
    7/23/2021$46.00 → $25.00Buy
    HC Wainwright & Co.
    More analyst ratings

    $MCRB
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    View All

    Director Shaff Eric D. converted options into 724 shares and sold $3,613 worth of shares (217 units at $16.65), increasing direct ownership by 5% to 10,609 units (SEC Form 4)

    4 - Seres Therapeutics, Inc. (0001609809) (Issuer)

    8/19/25 4:08:56 PM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Officer Desrosier Thomas converted options into 244 shares and sold $1,265 worth of shares (76 units at $16.65), increasing direct ownership by 2% to 7,455 units (SEC Form 4)

    4 - Seres Therapeutics, Inc. (0001609809) (Issuer)

    8/19/25 4:07:47 PM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Officer Henn Matthew R converted options into 238 shares and sold $1,215 worth of shares (73 units at $16.65), increasing direct ownership by 4% to 4,548 units (SEC Form 4)

    4 - Seres Therapeutics, Inc. (0001609809) (Issuer)

    8/19/25 4:07:27 PM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $MCRB
    FDA approvals

    Live FDA approvals issued by the Food and Drug Administration and FDA breaking news

    View All

    April 26, 2023 - FDA Approves First Orally Administered Fecal Microbiota Product for the Prevention of Recurrence of Clostridioides difficile Infection

    For Immediate Release: April 26, 2023 Today, the U.S. Food and Drug Administration approved Vowst, the first fecal microbiota product that is taken orally. Vowst is approved for the prevention of recurrence of Clostridioides difficile (C. difficile) infection (CDI) in individuals 18 years of age and older, following antibacterial treatment for recurrent CDI.  “Today’s approval provides patients and healthcare p

    4/26/23 6:04:21 PM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $MCRB
    SEC Filings

    View All

    Amendment: SEC Form SCHEDULE 13G/A filed by Seres Therapeutics Inc.

    SCHEDULE 13G/A - Seres Therapeutics, Inc. (0001609809) (Subject)

    8/6/25 12:23:55 PM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 10-Q filed by Seres Therapeutics Inc.

    10-Q - Seres Therapeutics, Inc. (0001609809) (Filer)

    8/6/25 10:00:49 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form 8-K filed by Seres Therapeutics Inc.

    8-K - Seres Therapeutics, Inc. (0001609809) (Filer)

    8/6/25 7:05:21 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $MCRB
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    View All

    Seres Therapeutics downgraded by Chardan Capital Markets with a new price target

    Chardan Capital Markets downgraded Seres Therapeutics from Buy to Neutral and set a new price target of $6.00

    5/8/25 8:27:44 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Seres Therapeutics downgraded by JP Morgan

    JP Morgan downgraded Seres Therapeutics from Neutral to Underweight

    10/24/24 6:25:19 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Oppenheimer resumed coverage on Seres Therapeutics with a new price target

    Oppenheimer resumed coverage of Seres Therapeutics with a rating of Outperform and set a new price target of $12.00

    6/26/23 7:26:19 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $MCRB
    Press Releases

    Fastest customizable press release news feed in the world

    View All

    Seres Therapeutics Reports Second Quarter 2025 Financial Results and Provides Business Updates

    Following FDA input, Seres submitted Phase 2 study protocol to FDA for SER-155 for the prevention of bloodstream infections (BSIs) in adults undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT) to treat hematological malignancies Seres engaging with multiple parties regarding various deal structures, including potential business development and partnerships, intended to secure capital and other resources to enable the clinical advancement of SER-155 and additional live biotherapeutic product candidates Seres received the $25 million installment payment, as expected, from Nestlé Health Science in July 2025 Conference call at 8:30 a.m. ET today CAM

    8/6/25 7:00:00 AM ET
    $MCRB
    $SANA
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Biotechnology: Biological Products (No Diagnostic Substances)

    Seres Therapeutics to Announce Second Quarter 2025 Financial Results and Business Updates on August 6, 2025

    CAMBRIDGE, Mass., July 22, 2025 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (NASDAQ:MCRB), a leading live biotherapeutics company, today announced that management will host a conference call and live audio webcast on August 6, 2025 at 8:30 a.m. ET to discuss second quarter 2025 financial results and provide business updates. To access the conference call, please dial 800-715-9871 (domestic) or 646-307-1963 (international) and reference the conference ID number 3641971. To join the live webcast, please visit the "Investors and News" section of the Seres website at www.serestherapeutics.com. A webcast replay will be available on the Seres website beginning approximately two hours afte

    7/22/25 7:01:00 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Seres Therapeutics Announces Leadership Transition

    Thomas DesRosier and Marella Thorell, accomplished biopharma executives, appointed co-CEOs; Eric Shaff stepping down as CEO and will remain a Director on the Seres Board Seres engaging with multiple parties regarding various deal structures, including potential business development and partnerships, intended to secure additional capital and other resources to enable the clinical advancement of SER-155 and additional live biotherapeutic product candidates CAMBRIDGE, Mass., July 22, 2025 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (NASDAQ:MCRB), (Seres or the Company), a leading live biotherapeutics company, today announced the appointment of Thomas DesRosier and Marella Thorell as co-Ch

    7/22/25 7:00:00 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $MCRB
    Financials

    Live finance-specific insights

    View All

    Seres Therapeutics Reports Second Quarter 2025 Financial Results and Provides Business Updates

    Following FDA input, Seres submitted Phase 2 study protocol to FDA for SER-155 for the prevention of bloodstream infections (BSIs) in adults undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT) to treat hematological malignancies Seres engaging with multiple parties regarding various deal structures, including potential business development and partnerships, intended to secure capital and other resources to enable the clinical advancement of SER-155 and additional live biotherapeutic product candidates Seres received the $25 million installment payment, as expected, from Nestlé Health Science in July 2025 Conference call at 8:30 a.m. ET today CAM

    8/6/25 7:00:00 AM ET
    $MCRB
    $SANA
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Biotechnology: Biological Products (No Diagnostic Substances)

    Seres Therapeutics to Announce Second Quarter 2025 Financial Results and Business Updates on August 6, 2025

    CAMBRIDGE, Mass., July 22, 2025 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (NASDAQ:MCRB), a leading live biotherapeutics company, today announced that management will host a conference call and live audio webcast on August 6, 2025 at 8:30 a.m. ET to discuss second quarter 2025 financial results and provide business updates. To access the conference call, please dial 800-715-9871 (domestic) or 646-307-1963 (international) and reference the conference ID number 3641971. To join the live webcast, please visit the "Investors and News" section of the Seres website at www.serestherapeutics.com. A webcast replay will be available on the Seres website beginning approximately two hours afte

    7/22/25 7:01:00 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Seres Therapeutics Reports First Quarter 2025 Financial Results and Provides Business Updates

    In line with recent FDA feedback, Seres expects to submit a Phase 2 study protocol to FDA in the coming weeks for SER-155 for the prevention of bloodstream infections (BSIs) in adults undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT) for the treatment of hematological malignancies SER-155 Phase 1b placebo-controlled study exploratory translational biomarker data reinforce intended mechanisms of action, consistent with clinical results that showed a significant reduction (77% relative risk reduction) in BSIs, and support broader potential for Seres' live biotherapeutics to address inflammatory and immune diseases Seres advancing SER-155 strategic partnership discussions i

    5/7/25 7:00:00 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $MCRB
    Leadership Updates

    Live Leadership Updates

    View All

    Seres Therapeutics Announces Leadership Transition

    Thomas DesRosier and Marella Thorell, accomplished biopharma executives, appointed co-CEOs; Eric Shaff stepping down as CEO and will remain a Director on the Seres Board Seres engaging with multiple parties regarding various deal structures, including potential business development and partnerships, intended to secure additional capital and other resources to enable the clinical advancement of SER-155 and additional live biotherapeutic product candidates CAMBRIDGE, Mass., July 22, 2025 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (NASDAQ:MCRB), (Seres or the Company), a leading live biotherapeutics company, today announced the appointment of Thomas DesRosier and Marella Thorell as co-Ch

    7/22/25 7:00:00 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    Flagship Appoints Amy O'Shea as CEO-Partner and Chief Executive Officer of Invaio Sciences

    O'Shea is a Seasoned Global Executive with more than 20 Years' Experience across the Agriculture, Food and Pharmaceutical Industries CAMBRIDGE, Mass., April 8, 2024 /PRNewswire/ -- Flagship Pioneering, the bioplatform innovation company, and Invaio Sciences, a bioplatform company accelerating the leap to nature-positive agriculture, today announced that Amy O'Shea has joined Flagship Pioneering as CEO-Partner and Invaio as Chief Executive Officer and Board Director. O'Shea is a seasoned global executive with more than 20 years' experience across the agriculture, food, and phar

    4/8/24 8:00:00 AM ET
    $DNLI
    $FHTX
    $MCRB
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Biotechnology: Pharmaceutical Preparations

    Seres Therapeutics Announces the Appointment of Marella Thorell as Chief Financial Officer and the Retirement of David Arkowitz

    Seres Therapeutics, Inc. (NASDAQ:MCRB), a leading microbiome therapeutics company, announced today that Marella Thorell will join as Executive Vice President and Chief Financial Officer (CFO), as of March 25th, following David Arkowitz's retirement. Mr. Arkowitz has served as CFO since June 2021 and will be available to assist in the transition. Ms. Thorell is a seasoned enterprise leader with deep life sciences and biotechnology industry experience in both public and private companies. Prior to joining Seres, she served in executive positions with Evelo Biosciences, Centessa Pharmaceuticals, Palladio Biosciences and Realm Therapeutics. "I am excited to welcome Marella and look forward

    2/26/24 7:00:00 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    $MCRB
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    View All

    Amendment: SEC Form SC 13D/A filed by Seres Therapeutics Inc.

    SC 13D/A - Seres Therapeutics, Inc. (0001609809) (Subject)

    10/2/24 8:15:49 AM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SC 13G/A filed by Seres Therapeutics Inc. (Amendment)

    SC 13G/A - Seres Therapeutics, Inc. (0001609809) (Subject)

    4/5/24 12:21:59 PM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care

    SEC Form SC 13G/A filed by Seres Therapeutics Inc. (Amendment)

    SC 13G/A - Seres Therapeutics, Inc. (0001609809) (Subject)

    2/12/24 12:23:38 PM ET
    $MCRB
    Biotechnology: Pharmaceutical Preparations
    Health Care