• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Dashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlerts
    Company
    AboutQuantisnow PlusContactJobs
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form S-8 filed by Acumen Pharmaceuticals Inc.

    3/27/25 4:38:20 PM ET
    $ABOS
    Biotechnology: Biological Products (No Diagnostic Substances)
    Health Care
    Get the next $ABOS alert in real time by email
    S-8 1 acumenpharma-sx82025.htm S-8 Document

    As filed with the Securities and Exchange Commission on March 27, 2025
    Registration No. 333-          
     
    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549
    FORM S-8 
    REGISTRATION STATEMENT
    UNDER
    THE SECURITIES ACT OF 1933
    Acumen Pharmaceuticals, Inc.
    (Exact name of registrant as specified in its charter)
    Delaware36-4108129
    (State or other jurisdiction of
    incorporation or organization)
    (I.R.S. Employer
    Identification No.)
    1210-1220 Washington St., Suite 210
    Newton, MA 02465
    (617) 344-4190 
    (Address of principal executive offices, including zip code)
    Acumen Pharmaceuticals, Inc. 2021 Equity Incentive Plan
    Acumen Pharmaceuticals, Inc. 2021 Employee Stock Purchase Plan
    (Full titles of the plans)
    Daniel O’Connell
    Chief Executive Officer
    Acumen Pharmaceuticals, Inc.
    1210-1220 Washington St., Suite 210
    Newton, MA 02465
    (617) 344-4190 
    (Name, address and telephone number, including area code, of agent for service)
    Copies to:
    Thomas J. Danielski, Esq. Derek Meisner
    Ropes & Gray LLPChief Legal Officer
    800 Boylston Street Acumen Pharmaceuticals, Inc.
    Boston, MA 02199
    1210-1220 Washington St., Suite 210
    (617) 951-7000
    Newton, MA 02465
    (617) 344-4190
    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
    Large accelerated filer☐Accelerated filer☐
    Non-accelerated filer☒Smaller reporting company☒
    Emerging growth company☒
    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐



    EXPLANATORY NOTE
    REGISTRATION OF ADDITIONAL SHARES
    Acumen Pharmaceuticals, Inc. (the “Registrant”) is filing this Registration Statement on Form S-8 with the Securities and Exchange Commission (the “Commission”) for the purpose of registering (i) 3,004,704 additional shares of its common stock under the 2021 Equity Incentive Plan (the “2021 Plan”), pursuant to the provisions of the 2021 Plan providing for an automatic increase in the number of shares of common stock reserved and available for issuance under the 2021 Plan on January 1, 2025, (ii) 38,192 additional shares of its common stock under the 2021 Plan pursuant to the provisions of the 2021 Plan providing that shares subject to outstanding stock options or other stock awards that were granted under the Registrant’s 2013 Amended and Restated Stock Performance Plan (the “Prior Plan”) that terminate or expire prior to exercise or settlement, are settled in cash, are forfeited or repurchased because of the failure to vest, or are reacquired or withheld to satisfy a tax withholding obligation or the purchase or exercise price in accordance with the terms of the Prior Plan become available for issuance under the 2021 Plan, and (iii) 600,941 additional shares of its common stock under the 2021 Employee Stock Purchase Plan (the “2021 ESPP,” and together with the 2021 Plan the “Plans”), pursuant to the provisions of the 2021 ESPP providing for an automatic increase in the number of shares of common stock reserved and available for issuance under the 2021 ESPP on January 1, 2025. Pursuant to General Instruction E to Form S-8, the Registrant incorporates by reference, except to the extent supplemented, amended or superseded by the information set forth herein, into this Registration Statement the entire contents of its Registration Statements on Form S-8 (File No. 333-257666) filed with the Commission on July 2, 2021, Form S-8 (File No. 333-263947) filed with the Commission on March 29, 2022, Form S-8 (File No. 333-270902) filed with the Commission on March 28, 2023 and Form S-8 (File No. 333-278267) filed with the Commission on March 27, 2024.



    PART II
    INFORMATION REQUIRED IN REGISTRATION STATEMENT
    ITEM 8. EXHIBITS
    Incorporated by Reference
    Exhibit
    Number
    DescriptionSchedule
    Form
    File NumberExhibitFiling Date
    3.1
    Amended and Restated Certificate of Incorporation of the Registrant.
    8-K001-405513.1June 8, 2023
    3.2
    Amended and Restated Bylaws of the Registrant.
    8-K001-405513.1March 15, 2023
    5.1*
    Opinion of Ropes & Gray LLP.
    23.1*
    Consent of Ropes & Gray LLP (included in Exhibit 5.1).
    23.2*
    Consent of Ernst & Young, LLP, independent registered public accounting firm.
    24.1*
    Power of Attorney (included on the signature page of this Form S-8). 
    99.1
    2021 Equity Incentive Plan and Forms of Option Grant Notice and Agreement, Exercise Notice, Early Exercise Notice and Restricted Stock Award Notice.
    S-1/A333-25694510.2June 24, 2021
    99.2
    2021 Employee Stock Purchase Plan
    S-1/A333-25694510.4June 24, 2021
    107*
    Filing Fee Table
    __________________
    *Filed herewith.



    SIGNATURES
    Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Newton, Commonwealth of Massachusetts, on March 27, 2025.
    ACUMEN PHARMACEUTICALS, INC.
    By:/s/ Daniel O’Connell
    Daniel O’Connell
    Chief Executive Officer
    POWER OF ATTORNEY
    KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Daniel O’Connell, William Matthew Zuga and Derek Meisner, and each one of them, as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in their name, place or stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this registration statement, and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or any of them, or his or her substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
    Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated.
    SignatureTitleDate
    /s/ Daniel O’Connell
    Chief Executive Officer and Director
    March 27, 2025
    Daniel O’Connell(Principal Executive Officer)
    /s/ William Matthew ZugaChief Financial Officer and Chief Business Officer
    March 27, 2025
    William Matthew Zuga(Principal Financial and Accounting Officer)
    /s/ Kimberlee C. DrapkinDirector
    March 27, 2025
    Kimberlee C. Drapkin
    /s/ Nathan B. FountainDirector
    March 27, 2025
    Nathan B. Fountain, M.D.
    /s/ Jeffrey L. IvesDirector
    March 27, 2025
    Jeffrey L. Ives, PhD
    /s/ Derrell D. PorterDirector
    March 27, 2025
    Derrell D. Porter, M.D.
    /s/ Sean StalfortDirector
    March 27, 2025
    Sean Stalfort
    /s/ Laura StoppelDirector
    March 27, 2025
    Laura Stoppel, PhD

    Get the next $ABOS alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $ABOS

    DatePrice TargetRatingAnalyst
    7/26/2024$7.00Buy
    Citigroup
    12/12/2023$8.00Buy
    Deutsche Bank
    7/20/2023$9.00 → $14.00Buy
    BofA Securities
    5/18/2023$13.00Overweight
    Cantor Fitzgerald
    7/15/2022$15.00Buy
    BTIG Research
    6/30/2022$15.00Buy
    H.C. Wainwright
    1/21/2022$16.00 → $14.00Neutral → Buy
    B of A Securities
    7/26/2021$27.00Buy
    UBS
    More analyst ratings

    $ABOS
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Acumen Pharmaceuticals Reports First Quarter 2025 Financial Results and Business Highlights

      Expect to report topline results for ALTITUDE-AD, a Phase 2 study to investigate sabirnetug (ACU193) for the treatment of early Alzheimer's disease, in late 2026 Cash, cash equivalents and marketable securities of $197.9 million as of March 31, 2025, expected to support current clinical and operational activities into early 2027  Company to host conference call and webcast today at 8:00 a.m. ET  NEWTON, Mass., May 13, 2025 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS) ("Acumen" or the "Company"), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers (AβOs) for the treatment of Alzheimer's disease (AD)

      5/13/25 7:00:00 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Acumen Pharmaceuticals to Participate in the Bank of America Healthcare Conference

      NEWTON, Mass., May 07, 2025 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, announced today that management will participate in in a fireside chat at the Bank of American Healthcare Conference on Wednesday, May 14, 2025, at 8:15 a.m. PT/11:15 a.m. ET. The live webcasts may be accessed under the Investors tab on www.acumenpharm.com and will be archived for 90 days. About Acumen Pharmaceuticals, Inc. Acumen Pharmaceuticals is a clinical-stage biopharmaceutical company developing a novel therapeutic that target

      5/7/25 4:00:00 PM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Acumen Pharmaceuticals to Report First Quarter 2025 Financial Results on May 13, 2025

      NEWTON, Mass., May 06, 2025 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS) ("Acumen" or the "Company"), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, today announced that the Company will report first quarter 2025 financial results on Tuesday, May 13, 2025. The Company will host a conference call and live audio webcast at 8:00 a.m. ET to provide a business and financial update. To participate in the live conference call, please register using this link. After registration, you will be informed of the dial-in numbers including PIN. Please register at l

      5/6/25 4:00:00 PM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $ABOS
    SEC Filings

    See more
    • SEC Form 10-Q filed by Acumen Pharmaceuticals Inc.

      10-Q - Acumen Pharmaceuticals, Inc. (0001576885) (Filer)

      5/13/25 4:36:39 PM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Acumen Pharmaceuticals Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Regulation FD Disclosure, Financial Statements and Exhibits

      8-K - Acumen Pharmaceuticals, Inc. (0001576885) (Filer)

      5/13/25 7:32:31 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form DEFA14A filed by Acumen Pharmaceuticals Inc.

      DEFA14A - Acumen Pharmaceuticals, Inc. (0001576885) (Filer)

      4/23/25 4:23:58 PM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $ABOS
    Financials

    Live finance-specific insights

    See more
    • Acumen Pharmaceuticals Reports First Quarter 2025 Financial Results and Business Highlights

      Expect to report topline results for ALTITUDE-AD, a Phase 2 study to investigate sabirnetug (ACU193) for the treatment of early Alzheimer's disease, in late 2026 Cash, cash equivalents and marketable securities of $197.9 million as of March 31, 2025, expected to support current clinical and operational activities into early 2027  Company to host conference call and webcast today at 8:00 a.m. ET  NEWTON, Mass., May 13, 2025 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS) ("Acumen" or the "Company"), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers (AβOs) for the treatment of Alzheimer's disease (AD)

      5/13/25 7:00:00 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Acumen Pharmaceuticals to Report First Quarter 2025 Financial Results on May 13, 2025

      NEWTON, Mass., May 06, 2025 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS) ("Acumen" or the "Company"), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, today announced that the Company will report first quarter 2025 financial results on Tuesday, May 13, 2025. The Company will host a conference call and live audio webcast at 8:00 a.m. ET to provide a business and financial update. To participate in the live conference call, please register using this link. After registration, you will be informed of the dial-in numbers including PIN. Please register at l

      5/6/25 4:00:00 PM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Acumen Pharmaceuticals Reports Financial Results for the Year Ended December 31, 2024 and Business Highlights

      Enrollment complete for ALTITUDE-AD, a Phase 2 study to investigate sabirnetug (ACU193) for the treatment of early Alzheimer's disease Anticipate topline results in late 2026 Topline results from the Phase 1 study investigating a subcutaneous sabirnetug formulation support further development of this dosing option for patientsCash, cash equivalents and marketable securities of $231.5 million as of Dec. 31, 2024, expected to support current clinical and operational activities into the first half of 2027Company to host conference call and webcast today at 8:00 a.m. ET  NEWTON, Mass., March 27, 2025 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS) ("Acumen" or the "Company"), a

      3/27/25 7:00:00 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $ABOS
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • SEC Form SC 13G/A filed by Acumen Pharmaceuticals Inc. (Amendment)

      SC 13G/A - Acumen Pharmaceuticals, Inc. (0001576885) (Subject)

      2/14/24 8:32:42 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13G filed by Acumen Pharmaceuticals Inc.

      SC 13G - Acumen Pharmaceuticals, Inc. (0001576885) (Subject)

      2/6/24 9:02:25 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • SEC Form SC 13G/A filed by Acumen Pharmaceuticals Inc. (Amendment)

      SC 13G/A - Acumen Pharmaceuticals, Inc. (0001576885) (Subject)

      1/24/24 4:22:26 PM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $ABOS
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Citigroup initiated coverage on Acumen Pharmaceuticals with a new price target

      Citigroup initiated coverage of Acumen Pharmaceuticals with a rating of Buy and set a new price target of $7.00

      7/26/24 7:19:00 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Deutsche Bank initiated coverage on Acumen Pharmaceuticals with a new price target

      Deutsche Bank initiated coverage of Acumen Pharmaceuticals with a rating of Buy and set a new price target of $8.00

      12/12/23 6:44:55 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • BofA Securities resumed coverage on Acumen Pharmaceuticals with a new price target

      BofA Securities resumed coverage of Acumen Pharmaceuticals with a rating of Buy and set a new price target of $14.00 from $9.00 previously

      7/20/23 7:18:27 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $ABOS
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • CFO & Chief Business Officer Zuga Matt sold $56,620 worth of shares (33,266 units at $1.70), decreasing direct ownership by 13% to 231,744 units (SEC Form 4)

      4 - Acumen Pharmaceuticals, Inc. (0001576885) (Issuer)

      1/23/25 9:19:28 PM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Chief Executive Officer Oconnell Daniel Joseph sold $20,102 worth of shares (12,619 units at $1.59), decreasing direct ownership by 2% to 667,488 units (SEC Form 4)

      4 - Acumen Pharmaceuticals, Inc. (0001576885) (Issuer)

      1/23/25 5:18:02 PM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Chief Legal Officer & Corp Sec Meisner Derek M sold $5,435 worth of shares (3,418 units at $1.59), decreasing direct ownership by 2% to 161,127 units (SEC Form 4)

      4 - Acumen Pharmaceuticals, Inc. (0001576885) (Issuer)

      1/23/25 5:16:46 PM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care

    $ABOS
    Leadership Updates

    Live Leadership Updates

    See more
    • Climb Bio Appoints Seasoned Biotech Leaders to Board of Directors

      WELLESLEY HILLS, Mass., April 01, 2025 (GLOBE NEWSWIRE) -- Climb Bio, Inc. (NASDAQ:CLYM) today announced the appointments of biotech industry veterans Kim Cobleigh Drapkin, CPA, and Bo Cumbo to its Board of Directors. Ms. Drapkin will assume the role of Audit Committee Chair, and Mr. Cumbo will assume the role of Compensation Committee Chair. "We are delighted to welcome Kim and Bo to our Board of Directors at Climb Bio," said Aoife Brennan, President and CEO of Climb Bio. "Kim and Bo each bring three decades of leadership experience in the biotechnology and pharmaceutical industry, offering invaluable perspective as we continue to build the company and advance our pipeline. Their insight

      4/1/25 7:00:00 AM ET
      $ABOS
      $CLYM
      $LENZ
      $SLDB
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
      Biotechnology: Pharmaceutical Preparations
    • Lucy Therapeutics Appoints Kim Drapkin as Board Chair

      Drapkin brings decades of biotech and pharma experience as the company prepares for clinical trial development. Lucy Therapeutics, Inc. (LucyTx), a biotech company developing proprietary small molecule therapies for complex neurological diseases including Rett syndrome, Parkinson's and Alzheimer's, today announced the appointment of Kim Drapkin as Board Chair. She will help guide the strategic direction of LucyTx as the company enters its next phase of growth: clinical trial development. "It's an honor to lead LucyTx's Board. The company's non-traditional approach to developing treatments for complex diseases is already paying off, and I'm eager to contribute to both their clinical and st

      10/15/24 8:00:00 AM ET
      $ABOS
      $LENZ
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care
    • Acumen Pharmaceuticals Appoints Dr. James Doherty as President and Chief Development Officer

      CHARLOTTESVILLE, Va., Feb. 01, 2024 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, announced today the appointment of James Doherty, Ph.D., as President and Chief Development Officer, effective February 1, 2024, reporting to Daniel O'Connell, Chief Executive Officer. Dr. Doherty's responsibilities will include oversight of clinical and non-clinical development, chemistry, manufacturing & controls and regulatory functions. "We are extremely excited to welcome Jim, who brings extensive experience and demonstrat

      2/1/24 7:00:00 AM ET
      $ABOS
      Biotechnology: Biological Products (No Diagnostic Substances)
      Health Care