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    SEC Form S-8 filed by Amylyx Pharmaceuticals Inc.

    3/4/25 4:06:02 PM ET
    $AMLX
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $AMLX alert in real time by email
    S-8 1 d921516ds8.htm S-8 S-8

    As filed with the Securities and Exchange Commission on March 4, 2025

    Registration No. 333-   

     

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

     

    FORM S-8

    REGISTRATION STATEMENT

    Under

    The Securities Act of 1933

     

     

    AMYLYX PHARMACEUTICALS, INC.

    (Exact name of registrant as specified in its charter)

     

     

     

    Delaware   46-4600503

    (State or other jurisdiction of

    incorporation or organization)

     

    (I.R.S. Employer

    Identification No.)

    43 Thorndike St.

    Cambridge, MA 02141

    (617) 682-0917

    (Address, including zip code and telephone number, including area code, of Registrant’s principal executive offices)

    Amylyx Pharmaceuticals, Inc. 2022 Stock Option and Incentive Plan

    Amylyx Pharmaceuticals, Inc. 2022 Employee Stock Purchase Plan

    (Full title of the plans)

    Joshua B. Cohen, Co-Chief Executive Officer

    Justin B. Klee, Co-Chief Executive Officer

    Amylyx Pharmaceuticals, Inc.

    43 Thorndike St.

    Cambridge, MA 02141

    (617) 682-0917

    (Name, address, including zip code, and telephone number, including area code, of agent for service)

     

     

    Copies to:

    Benjamin K. Marsh, Esq.

    Marishka DeToy, Esq.

    Goodwin Procter LLP

    100 Northern Avenue

    Boston, MA 02210

    (617) 570-1000

     

     

    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

     

    Large accelerated filer   ☐    Accelerated filer   ☒
    Non-accelerated filer   ☐    Smaller reporting company   ☒
         Emerging growth company   ☐

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

     

     

     


    Statement of Incorporation by Reference

    This Registration Statement on Form S-8 is filed to register the offer and sale of (i) an additional 3,431,486 shares of the Registrant’s common stock, $0.0001 par value per share (the “Common Stock”), to be issued under the Registrant’s 2022 Stock Option and Incentive Plan and (ii) an additional 686,297 shares of Common Stock to be issued under the Registrant’s 2022 Employee Stock Purchase Plan. This Registration Statement incorporates by reference the contents of the registration statements on Form S-8 (File No.  333-262125, File No.  333-270509 and File No.  333-277274) filed by the Registrant on January 12, 2022, March 13, 2023 and February 22, 2024, respectively.

    Part II

    Information Required in the Registration Statement

    Item 8. Exhibits.

    See the Exhibit Index below for a list of exhibits filed as part of this registration statement on Form S-8, which Exhibit Index is incorporated herein by reference.

    EXHIBIT INDEX

     

    Exhibit

    No.

      

    Description

    4.1    Fourth Amended and Restated Certificate of Incorporation of Amylyx Pharmaceuticals, Inc. (Incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on January 11, 2022). 
    4.2    Second Amended and Restated Bylaws of Amylyx Pharmaceuticals, Inc. (Incorporated by reference to Exhibit 3.2 to the Registrant’s Current Report on Form 8-K, filed with the Securities and Exchange Commission on January 11, 2022).
    4.3    Second Amended and Restated Investors’ Rights Agreement among the Registrant and certain of its stockholders, dated July  1, 2021 (Incorporated by reference to Exhibit 4.2 to the Registrant’s Registration Statement on Form S-1, as amended (File No.  333-261703), filed with the Securities and Exchange Commission on December 16, 2021). 
    5.1*    Opinion of Goodwin Procter LLP.
    23.1*    Consent of Deloitte & Touche LLP, Independent Registered Public Accounting Firm.
    23.2*    Consent of Goodwin Procter LLP (included in Exhibit 5.1).
    24.1*    Power of Attorney (included on signature page).
    99.1    2022 Stock Option and Incentive Plan, and form of award agreements thereunder (Incorporated by reference to Exhibit 10.2 to the Registrant’s Registration Statement on Form S-1/A (File No. 333-261703) filed with the Securities and Exchange Commission on January 3, 2022).
    99.2    2022 Employee Stock Purchase Plan (Incorporated by reference to Exhibit 10.3 to the Registrant’s Registration Statement on Form S-1/A (File No. 333-261703) filed with the Securities and Exchange Commission on January 3, 2022).
    107*    Filing Fee Table.

     

    *

    Filed herewith.


    SIGNATURES

    Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Cambridge, State of Massachusetts, on this 4th day of March, 2025.

     

    AMYLYX PHARMACEUTICALS, INC.
    By:  

    /s/ Joshua Cohen

     

    Joshua Cohen

    Co-Chief Executive Officer and Director

    By:  

    /s/ Justin Klee

     

    Justin Klee

    Co-Chief Executive Officer and Director

    POWER OF ATTORNEY AND SIGNATURES

    KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Joshua Cohen and Justin Klee and each of them, his true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution for him and in his name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement on Form S-8, and to file the same, with all exhibits thereto, and all other documents in connection therewith, with the Securities and Exchange Commission, granting unto each said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming all that each of said attorney-in-fact or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

    Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the date indicated.


    Name       Title   Date

    /s/ Joshua Cohen

        Co-Chief Executive Officer and Director (Principal Executive Officer)   March 4, 2025
    Joshua Cohen  

    /s/ Justin Klee

        Co-Chief Executive Officer and Director (Principal Executive Officer)   March 4, 2025
    Justin Klee  

    /s/ James M. Frates

       

    Chief Financial Officer (Principal Financial Officer and

    Principal Accounting Officer)

      March 4, 2025
    James M. Frates, MBA  

    /s/ Karen Firestone

        Director   March 4, 2025
    Karen Firestone      

    /s/ George Mclean Milne Jr.

        Director   March 4, 2025
    George Mclean Milne Jr., Ph.D.  

    /s/ Paul Fonteyne

        Director   March 4, 2025
    Paul Fonteyne, MS, MBS  

    /s/ Daphne Quimi

        Director   March 4, 2025
    Daphne Quimi, MBA  

    /s/ Bernhardt Zeiher

        Director   March 4, 2025
    Bernhardt Zeiher, MD  
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