• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Dashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlerts
    Company
    AboutQuantisnow PlusContactJobs
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form S-8 filed by Monopar Therapeutics Inc.

    3/31/25 8:04:06 AM ET
    $MNPR
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $MNPR alert in real time by email
    S-8 1 mnpr20250328_s8.htm FORM S-8 mnpr20250328_s8.htm

     

    As filed with the Securities and Exchange Commission on March 31, 2025

    Registration No. 333-

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    Washington, D.C. 20549

     

    FORM S-8

     

    REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

     

    Monopar Therapeutics Inc.

    (Exact name of registrant as specified in its charter)

     

    Delaware

    (State or other jurisdiction of incorporation or organization)

    32-0463781

    (I.R.S. Employer Identification No.)

     

    1000 Skokie Blvd., Suite 350

    Wilmette, IL 60091

    (Address of principal executive offices) (Zip Code)

     

    Monopar Therapeutics Inc. 2016 Stock Incentive Plan

    (Full title of the plans)

     

    Chandler D. Robinson

    Chief Executive Officer

    1000 Skokie Blvd., Suite 350

    Wilmette, IL 60091

    (Name and Address of agent for service)

     

    (847) 388-0349

    (Telephone number, including area code, of agent for service)

     

     

    With a copy to:

     

    John J. Harrington

    Sean D. Cheatle

    Baker & Hostetler LLP

    127 Public Square, Suite 2000

    Cleveland, OH 44114

    (216) 861-6697

     

    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

     

    Large accelerated filer ☐

    Accelerated filer ☐

    Non-accelerated filer ☒

     

    Smaller Reporting Company ☒

    Emerging growth company ☐

     

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐

     

     

     

     

    REGISTRATION OF ADDITIONAL SHARES PURSUANT TO GENERAL INSTRUCTION E

     

    This Registration Statement on Form S-8 (the “Registration Statement”) of Monopar Therapeutics Inc. (the “Company” or the “Registrant”) is being filed pursuant to General Instruction E to Form S-8 under the Securities Act of 1933, as amended, to register 400,000 additional shares of the Company’s common stock, $0.001 par value per share (the “Common Stock”), under the 2016 Stock Incentive Plan, as amended (the “Plan”).

     

    This Registration Statement on Form S-8 hereby incorporates by reference the contents of the Registrant’s registration statements on Forms S-8 filed with the Securities and Exchange Commission (the “SEC”) on January 3, 2020 (Registration No. 333-235790), November 13, 2020 (Registration No. 333-250046), and August 12, 2022 (Registration No. 333-266828),

     

     

     

     

     

    PART II

     

    INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

     

    Item 3. Incorporation of Documents by Reference

     

    The following documents filed by the Registrant with the Commission are incorporated herein by reference:

     

     

    ●

    The Registrant’s Annual Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on March 31, 2025;

     

     

    ●

    The description of the Registrant’s capital stock contained in Exhibit 4.1 to the Company’s Annual Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on March 31, 2025; and

     

     

    ●

    The Registrant’s Current Reports on Form 8-K filed with the SEC on February 24, 2025 and March 3, 2025.

     

    All reports and other documents filed by the Registrant after the date hereof pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act of 1934, as amended, prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference herein and to be part hereof from the date of filing of such reports and documents. Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for the purposes of this Registration Statement to the extent that a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated by reference herein modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.

     

    Exhibit

    Number

      Description
    5.1   Opinion of Legal Counsel
    10.1   Monopar Therapeutics Inc. 2016 Stock Incentive Plan, as amended (incorporated by reference to Exhibit 10.18 to Monopar Therapeutics Inc.’s Annual Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on March 31, 2025)

    23.1

     

    Consent of Independent Registered Public Accounting Firm

    23.2

     

    Consent of Legal Counsel (included in Exhibit 5.1)

    24.1

     

    Power of Attorney (included on signature page)

    107   Filing Fee Table

     

    II-1

     

     

    SIGNATURES

     

    Pursuant to the requirements of the Securities Act of 1933, as amended, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in Wilmette, Illinois, on the 31st day of March, 2025

     

     

    MONOPAR THERAPEUTICS INC

     

     

     

     

     

     

     

     

     

    Dated: March 31, 2025

    By:

    /s/ Quan Vu

     

     

     

    Name: Quan Vu

     

     

     

    Title: Chief Financial Officer

     

        (Principal Financial Officer)  

     

     

    POWER OF ATTORNEY

     

    KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Chandler D. Robinson and Quan Vu, and each of them, his/her true and lawful attorney-in-fact and agent with full power of substitution and re-substitution, for him/her and in his/her name, place and stead, in any and all capacities to sign any or all amendments (including, without limitation, post-effective amendments) to this Registration Statement, any related Registration Statement filed pursuant to Rule 462(b) under the Securities Act of 1933 and any or all pre- or post-effective amendments thereto, and to file the same, with all exhibits thereto, and all other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact and agent, full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully for all intents and purposes as he/she might or could do in person, hereby ratifying and confirming that said attorney-in-fact and agent, or any substitute or substitutes for him, may lawfully do or cause to be done by virtue hereof.

     

    Pursuant to the requirements of the Securities Act of 1933, the following persons in the capacities and on the dates indicated have signed this Registration Statement below.

     

    Signatures

     

    Title

     

    Date

           

     

    /s/ Chandler D. Robinson       March 31, 2025

    Chandler D. Robinson

     

    Chief Executive Officer and Director

    (Principal Executive Officer)

       
             
    /s/ Quan Vu      

    March 31, 2025

    Quan Vu

     

    Chief Financial Officer (Principal Financial

    Officer and Principal Accounting Officer)

       
             
    /s/ Christopher M. Starr      

    March 31, 2025

    Christopher M. Starr

     

    Executive Chairman of the Board and Director

       
             
    /s/ Raymond W. Anderson      

    March 31, 2025

    Raymond W. Anderson

     

    Director

       
           

     

    /s/ Arthur J. Klausner       March 31, 2025

    Arthur J. Klausner

     

    Director

       
             
    /s/ Kim R. Tsuchimoto      

    March 31, 2025

    Kim R. Tsuchimoto

     

    Director

       
             
    /s/ Lavina Talukdar      

    March 31, 2025

    Lavina Talukdar

     

    Director

       

     

    II-2
    Get the next $MNPR alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $MNPR

    DatePrice TargetRatingAnalyst
    3/19/2025$76.00Overweight
    Piper Sandler
    1/10/2025$72.00Overweight
    Piper Sandler
    10/11/2024$50.00Buy
    Rodman & Renshaw
    11/1/2021$9.00Buy
    HC Wainwright & Co.
    More analyst ratings

    $MNPR
    SEC Filings

    See more
    • Amendment: SEC Form SCHEDULE 13G/A filed by Monopar Therapeutics Inc.

      SCHEDULE 13G/A - Monopar Therapeutics (0001645469) (Subject)

      5/14/25 11:59:32 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form 10-Q filed by Monopar Therapeutics Inc.

      10-Q - Monopar Therapeutics (0001645469) (Filer)

      5/13/25 8:00:57 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Monopar Therapeutics Inc. filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

      8-K - Monopar Therapeutics (0001645469) (Filer)

      5/13/25 8:00:09 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MNPR
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • Monopar Therapeutics Reports First Quarter 2025 Financial Results and Recent Developments

      WILMETTE, Illinois, May 13, 2025 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. ("Monopar" or the "Company") (NASDAQ:MNPR), a clinical‐stage biopharmaceutical company focused on developing innovative treatments for patients with unmet medical needs, today announced first quarter 2025 financial results and recent developments. Recent Developments ALXN1840 for Wilson Disease On May 7, 2025, Monopar presented long-term efficacy and safety data for ALXN1840 (tiomolybdate choline) at the European Association for the Study of the Liver ("EASL") International Liver Congress 2025, a leading global conference in liver disease. The data support ALXN1840 as a potential treatment for Wilson disease

      5/13/25 8:00:00 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Monopar Presents ALXN1840 Late-Breaker Data at EASL 2025

      WILMETTE, Ill., May 07, 2025 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (NASDAQ:MNPR), a clinical-stage biopharmaceutical company focused on developing innovative treatments for patients with unmet medical needs, is presenting today data on the long term efficacy and safety of its ALXN1840 (tiomolybdate choline) drug candidate for Wilson disease at the European Association for the Study of the Liver ("EASL") International Liver Congress 2025, one of the most prominent global conferences in liver disease. Monopar's late-breaker poster presentation is available at the following link: https://www.monopartx.com/pipeline/ALXN1840/EASL-poster-may-2025. The poster supports the potential use o

      5/7/25 2:30:00 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Monopar Announces ALXN1840 Data Selected for Late-Breaker Presentation at EASL Congress 2025

      WILMETTE, Ill., April 29, 2025 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (NASDAQ:MNPR), a clinical-stage biopharmaceutical company focused on developing innovative treatments for patients with unmet medical needs, today announced that data on the long term efficacy and safety of its ALXN1840 (tiomolybdate choline) drug candidate for Wilson disease has been accepted for a late-breaker poster presentation at the European Association for the Study of the Liver ("EASL") International Liver Congress 2025. EASL is recognized as one of the premier events in the hepatology space and will be held in Amsterdam, Netherlands from May 7 – 10, 2025. Late-breaker provides an opportunity to present "

      4/29/25 8:00:00 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MNPR
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Chief Financial Officer Radhakrishnan Karthik bought $25,188 worth of shares (1,550 units at $16.25) (SEC Form 4)

      4 - Monopar Therapeutics (0001645469) (Issuer)

      10/30/24 4:17:28 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Operating Officer Cittadine Andrew bought $25,574 worth of shares (32,508 units at $0.79), increasing direct ownership by 21% to 186,132 units (SEC Form 4)

      4 - Monopar Therapeutics (0001645469) (Issuer)

      6/21/24 5:16:51 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Operating Officer Cittadine Andrew bought $32,894 worth of shares (36,000 units at $0.91), increasing direct ownership by 31% to 153,624 units (SEC Form 4)

      4 - Monopar Therapeutics (0001645469) (Issuer)

      6/17/24 6:08:20 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MNPR
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Piper Sandler resumed coverage on Monopar Therapeutics with a new price target

      Piper Sandler resumed coverage of Monopar Therapeutics with a rating of Overweight and set a new price target of $76.00

      3/19/25 8:17:26 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Piper Sandler initiated coverage on Monopar Therapeutics with a new price target

      Piper Sandler initiated coverage of Monopar Therapeutics with a rating of Overweight and set a new price target of $72.00

      1/10/25 8:29:30 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Rodman & Renshaw initiated coverage on Monopar Therapeutics with a new price target

      Rodman & Renshaw initiated coverage of Monopar Therapeutics with a rating of Buy and set a new price target of $50.00

      10/11/24 7:49:44 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MNPR
    Insider purchases explained

    Analytical look into recent insider purchases

    See more
    • What Does the Recent Purchase at Monopar Therapeutics Inc. on Jun 21 Indicate?

      Monopar Therapeutics Inc. has recently seen notable insider activity, with Chief Operating Officer Cittadine Andrew purchasing $25,574 worth of shares on June 21st, 2024. This purchase, comprising 32,508 units at $0.79, increased Cittadine's direct ownership by 21% to 186,132 units as reported in the SEC Form 4. When analyzing this transaction alongside other recent insider activities within the company, interesting patterns and trends start to emerge. Looking back, Cittadine Andrew has been consistently adding to his position in Monopar Therapeutics Inc. over the past few months, showcasing a strong conviction in the company's future prospects. On May 31st, Cittadine Andrew made a substan

      6/22/24 8:00:00 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MNPR
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Large owner Tactic Pharma Llc sold $1,166,690 worth of shares (33,334 units at $35.00) (SEC Form 4)

      4 - Monopar Therapeutics (0001645469) (Issuer)

      4/4/25 7:27:32 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Operating Officer Cittadine Andrew covered exercise/tax liability with 744 shares and converted options into 1,791 shares, increasing direct ownership by 3% to 41,985 units (SEC Form 4)

      4 - Monopar Therapeutics (0001645469) (Issuer)

      4/2/25 9:08:37 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Chief Executive Officer Robinson Chandler converted options into 4,106 shares and covered exercise/tax liability with 1,204 shares, increasing direct ownership by 5% to 65,993 units (SEC Form 4)

      4 - Monopar Therapeutics (0001645469) (Issuer)

      4/2/25 9:07:37 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MNPR
    Leadership Updates

    Live Leadership Updates

    See more
    • Rosalind Franklin University's Helix 51 Incubator Welcomes Monopar Therapeutics

      Monopar's pipeline includes clinical-stage radiopharmaceuticals targeting advanced solid tumors and late-stage ALXN1840, a treatment for Wilson Disease  NORTH CHICAGO, Ill., Jan. 23, 2025 /PRNewswire/ -- Rosalind Franklin University of Medicine and Science announced that Monopar Therapeutics is the latest biotech company to join the Helix 51 biomedical incubator community. Monopar, a clinical-stage biotechnology firm, is developing personalized and precise radiopharmaceuticals to diagnose and treat aggressive cancers, and will utilize the labs and other resources in Helix 51 t

      1/23/25 1:10:00 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Monopar Appoints Octávio Costa, MD, as Chief Medical Officer

      WILMETTE, Ill., July 12, 2021 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (NASDAQ:MNPR), a clinical-stage biopharmaceutical company primarily focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients, today announced the appointment of Octávio Costa, MD, as Chief Medical Officer. In this role, Dr. Costa will oversee global clinical development and regulatory affairs, and will provide strategic direction for Monopar's pipeline. Dr. Costa joins Monopar with over 30 years of experience overseeing clinical development, clinical operations, development strategy and global medical affairs. He has extensive Phase 1 through 4 clini

      7/12/21 8:00:00 AM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Monopar Therapeutics Expands Leadership Team with Appointment of Andrew Cittadine as Chief Operating Officer

      WILMETTE, Ill., June 01, 2021 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (NASDAQ:MNPR), a clinical-stage biopharmaceutical company primarily focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients, today announced the appointment of Andrew Cittadine, MBA, as Chief Operating Officer. In this role, Mr. Cittadine will provide leadership and oversight of Monopar's global operations and business and development strategy. Mr. Cittadine is an experienced healthcare executive and serial entrepreneur with a successful track record of identifying, founding, and building healthcare businesses from concept to commercialization

      6/1/21 4:05:00 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $MNPR
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • Amendment: SEC Form SC 13D/A filed by Monopar Therapeutics Inc.

      SC 13D/A - Monopar Therapeutics (0001645469) (Subject)

      12/17/24 5:01:42 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G filed by Monopar Therapeutics Inc.

      SC 13G - Monopar Therapeutics (0001645469) (Subject)

      11/6/24 3:13:14 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G filed by Monopar Therapeutics Inc.

      SC 13G - Monopar Therapeutics (0001645469) (Subject)

      10/31/24 4:17:57 PM ET
      $MNPR
      Biotechnology: Pharmaceutical Preparations
      Health Care