• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Dashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlerts
    Company
    AboutQuantisnow PlusContactJobs
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form S-8 POS filed by Advaxis, Inc.

    4/15/24 4:32:50 PM ET
    $ADXS
    Major Pharmaceuticals
    Health Care
    Get the next $ADXS alert in real time by email
    S-8 POS 1 forms-8.htm
    As filed with the Securities and Exchange Commission on April 15, 2024

    Registration No. 333-130080
    Registration No. 333-193007
    Registration No. 333-197465
    Registration No. 333-204939
    Registration No. 333-210285
    Registration No. 333-217218
    Registration No. 333-222483
    Registration No. 333-223851
    Registration No. 333-239469
     

     UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549
    ___________________
     
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.  333-130080
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.  333-193007
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.  333-197465
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.  333-204939
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.  333-210285
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.  333-217218
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.  333-222483
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.  333-223851
    POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8 REGISTRATION STATEMENT NO.  333-239469

    UNDER THE SECURITIES ACT OF 1933
    ___________________
     
    AYALA PHARMACEUTICALS, INC.
    (Exact name of registrant as specified in its charter)
    ___________________
     
    Delaware
     
    84-1521955
    (State or other jurisdiction
    of incorporation or organization)
     
    (I.R.S. Employer Identification No.)
     
    9 Deer Park Drive, Suite K-1
    Monmouth Junction, NJ 08852
    (Address and Zip Code of Principal Executive Office)
     
    Advaxis, Inc. 2004 Stock Option Plan
    Advaxis, Inc. 2005 Stock Option Plan
    Advaxis, Inc. Amended and Restated 2009 Stock Option Plan
    Advaxis, Inc. 2011 Omnibus Incentive Plan
    Advaxis, Inc. 2011 Employee Stock Purchase Plan
    Advaxis, Inc. 2011 Omnibus Incentive Plan, as amended
    Advaxis, Inc. 2015 Incentive Plan
    Advaxis, Inc. 2018 Employee Stock Purchase Plan
    (Full titles of the plans)
     
    Kenneth A. Berlin, Chief Executive Officer
    Ayala Pharmaceuticals, Inc.
    9 Deer Park Drive, Suite K-1
    Monmouth Junction, NJ 08852
    (732) 545-1590
     (Name, address, and telephone number,
    including area code, of agent for service)
     

     Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
     
    Large accelerated filer
    □
     
    Accelerated filer
    □
    Non-accelerated filer
    ⌧
     
    Smaller reporting company
    ⌧
    v 
     
     
    Emerging growth company
    □
     
    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. □
     
     
     







    DEREGISTRATION OF SECURITIES
     
    This Post-Effective Amendment (the “Post-Effective Amendment”) filed by Ayala Pharmaceuticals, Inc., a Delaware corporation (the “Company”), deregisters all shares of common stock of the Company, par value $0.001 per share (the “Common Stock”), that remain unsold under the following Registration Statements on Form S-8 (each a “Registration Statement,” and collectively, the “Registration Statements”) filed by the Company with the U.S. Securities and Exchange Commission (the “Commission”):
     

    •
    Registration Statement on Form S-8 (No. 333-130080), which was filed with the Commission on December 1, 2005, pertaining to the registration of 2,381,525 shares of Common Stock issuable under the Advaxis, Inc. 2004 Stock Option Plan.


    •
     Registration Statement on Form S-8 (No. 333-193007), which was filed with the Commission on December 20, 2013, pertaining to the registration of 698,611 shares of Common Stock issuable under the Advaxis, Inc. 2005 Stock Option Plan, the Advaxis, Inc. 2009 Amended and Restated Stock Option Plan, the Advaxis, Inc. 2011 Omnibus Incentive Plan and the Advaxis, Inc. 2011 Employee Stock Purchase Plan.


    •
    Registration Statement on Form S-8 (No. 333-197465), which was filed with the Commission on July 16, 2014, pertaining to the registration of 1,600,000 shares of Common Stock issuable under the Advaxis, Inc. 2011 Omnibus Incentive Plan, as amended.


    •
    Registration Statement on Form S-8 (No. 333-204939), which was filed with the Commission on June 15, 2015, pertaining to the registration of 4,250,000 shares of Common Stock issuable under the Advaxis, Inc. 2015 Incentive Plan.


    •
    Registration Statement on Form S-8 (No. 333-210285), which was filed with the Commission on March 18, 2016, pertaining to the registration of 1,000,000 shares of Common Stock issuable under the Advaxis, Inc. 2015 Incentive Plan.


    •
    Registration Statement on Form S-8 (No. 333-217218), which was filed with the Commission on April 7, 2017, pertaining to the registration of 1,520,000 shares of Common Stock issuable under the Advaxis, Inc. 2015 Incentive Plan and the Advaxis, Inc. 2011 Employee Stock Purchase Plan.


    •
    Registration Statement on Form S-8 (No. 333-222483), which was filed with the Commission on January 9, 2018, pertaining to the registration of 2,070,147 shares of Common Stock issuable under the Advaxis, Inc. 2015 Incentive Plan and the Advaxis, Inc. 2011 Employee Stock Purchase Plan.


    •
    Registration Statement on Form S-8 (No. 333-223851), which was filed with the Commission on March 22, 2018, pertaining to the registration of 1,000,000 shares of Common Stock issuable under the Advaxis, Inc. 2018 Employee Stock Purchase Plan.


    •
    Registration Statement on Form S-8 (No. 333-293469), which was filed with the Commission on June 26, 2020, pertaining to the registration of 6,062,257 shares of Common Stock issuable under the Advaxis, Inc. 2015 Incentive Plan.
     
    On March 25, 2024, the Company and Immunome, Inc. (“Purchaser”) consummated the transactions contemplated by that certain Asset Purchase Agreement, dated as of March 5, 2024 (the “Asset Purchase Agreement”) pursuant to which Purchaser agreed to acquire, and the Company agreed to sell, certain of the Company’s assets and liabilities related to its AL101 and AL102 programs (the “Asset Sale”), which constitute substantially all of the Company’s assets.

    Following the completion of the Asset Sale, the Company wishes to terminate the offerings pursuant to the above-referenced Registration Statements.  In accordance with undertakings made by the Company in the Registration Statements to remove from registration, by means of a post-effective amendment, any of the securities that remain unsold at the termination of the offerings, the Company hereby removes from registration any and all securities registered but unsold under each of the Registration Statements.  Each of the Registration Statements is hereby amended, as appropriate, to reflect the deregistration of such securities.
     

    SIGNATURE
     
    Pursuant to the requirements of the Securities Act of 1933, as amended, the Company certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Post-Effective Amendment to the above-referenced Registration Statements to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Monmouth Junction, State of New Jersey, on this 15th day of April, 2024.
     

     
     
         
     
    Ayala Pharmaceuticals, Inc.
     
     
     
     
     
     
     
    By:
    /s/ Kenneth A. Berlin
     
     
    Name:
    Kenneth A. Berlin
     
     
    Title:
    President and Chief Executive Officer


    *            Pursuant to Rule 478 under the Securities Act of 1933, as amended, no other person is required to sign this Post-Effective Amendment to the Registration Statement.

    Get the next $ADXS alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $ADXS

    DatePrice TargetRatingAnalyst
    More analyst ratings

    $ADXS
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • SEC Form 4 filed by Israel Biotech Fund I, L.P.

      4 - Ayala Pharmaceuticals, Inc. (0001100397) (Issuer)

      3/6/24 7:13:01 AM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • Israel Biotech Fund I, L.P. exercised 27,847,159 shares at a strike of $0.40 and covered exercise/tax liability with 5,294,486 shares (SEC Form 4)

      4 - Ayala Pharmaceuticals, Inc. (0001100397) (Issuer)

      2/12/24 2:16:21 PM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • SEC Form 4 filed by Israel Biotech Fund I, L.P.

      4 - Ayala Pharmaceuticals, Inc. (0001100397) (Issuer)

      11/21/23 9:04:41 AM ET
      $ADXS
      Major Pharmaceuticals
      Health Care

    $ADXS
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • OS Therapies Agrees to Acquire All Listeria Monotygenes-based Immuno-Oncology Programs and IP Assets from Ayala Pharmaceuticals, Adding Phase 2 Lung Cancer and Phase 1 Prostrate Cancer Programs to Pipeline

      Consolidates ownership of listeria monocytogenes-based immunotherapy IP Eliminates milestone payments and reduces future royalty obligations relating to OST-HER2 for osteosarcoma and other HER2-related indications Capital allocation focus remains on regulatory approval, priority review voucher (PRV) issuance and commercialization of OST-HER2 in osteosarcoma Previously disclosed $7.1M funding for OS therapies priced at $4.00/share provides cash runway into 2026 & precludes raises below $12.00 for 6 months Karim Galzahr appointed to OS Therapies Board of Directors OS Therapies, Inc. (NYSE-A: OSTX), a clinical-stage biotechnology company advancing immunotherapies and targeted d

      1/29/25 9:22:00 AM ET
      $ADXS
      $OSTX
      Major Pharmaceuticals
      Health Care
      Biotechnology: Pharmaceutical Preparations
    • Ayala Pharmaceuticals Files Form 15 to Voluntarily Deregister and Suspend its Reporting Obligations

      MONMOUTH JUNCTION, N.J., May 09, 2024 (GLOBE NEWSWIRE) -- Ayala Pharmaceuticals, Inc. (OTCQX:ADXS), a clinical-stage oncology company, today announced that it filed a Form 15 with the Securities and Exchange Commission (the "SEC") to deregister its common stock under Section 12(g) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and to suspend its reporting obligations under Section 15(d) of the Exchange Act. The Company's obligation to file periodic reports with the SEC, including reports on Forms 10-K, 10-Q and 8-K, will be suspended immediately upon filing of the Form 15. Once the Form 15 is effective, which is expected to occur within 90 days of filing, the Comp

      5/9/24 4:10:00 PM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • Ayala Pharmaceuticals Announces Completion of Sale of AL102 to Immunome

      MONMOUTH JUNCTION, N.J., March 26, 2024 (GLOBE NEWSWIRE) -- Ayala Pharmaceuticals, Inc. (OTCQX:ADXS), a clinical-stage oncology company, today announced the completion of the previously announced sale of AL102, and related drug candidate AL101, to Immunome, Inc. (NASDAQ:IMNM). As per the terms of the sale, Ayala received from Immunome $20 million in cash and 2,175,489 shares of Immunome common stock, and Immunome assumed specified liabilities related to AL102. Ayala may also receive up to an additional $37.5 million in development and commercial milestone payments. "We are pleased that AL102 will now be advanced by the highly experienced team at Immunome," said Ken Berlin, President and

      3/26/24 8:00:00 AM ET
      $ADXS
      $IMNM
      Major Pharmaceuticals
      Health Care
      Biotechnology: Pharmaceutical Preparations

    $ADXS
    Leadership Updates

    Live Leadership Updates

    See more
    • OS Therapies Agrees to Acquire All Listeria Monotygenes-based Immuno-Oncology Programs and IP Assets from Ayala Pharmaceuticals, Adding Phase 2 Lung Cancer and Phase 1 Prostrate Cancer Programs to Pipeline

      Consolidates ownership of listeria monocytogenes-based immunotherapy IP Eliminates milestone payments and reduces future royalty obligations relating to OST-HER2 for osteosarcoma and other HER2-related indications Capital allocation focus remains on regulatory approval, priority review voucher (PRV) issuance and commercialization of OST-HER2 in osteosarcoma Previously disclosed $7.1M funding for OS therapies priced at $4.00/share provides cash runway into 2026 & precludes raises below $12.00 for 6 months Karim Galzahr appointed to OS Therapies Board of Directors OS Therapies, Inc. (NYSE-A: OSTX), a clinical-stage biotechnology company advancing immunotherapies and targeted d

      1/29/25 9:22:00 AM ET
      $ADXS
      $OSTX
      Major Pharmaceuticals
      Health Care
      Biotechnology: Pharmaceutical Preparations
    • Ascentage Pharma Appoints Renowned Oncologist Dr. David Sidransky, MD, to its Board as an Independent Non-Executive Director

      SUZHOU, China and ROCKVILLE, Md., April 2, 2021 /PRNewswire/ -- Ascentage Pharma (6855.HK), a globally focused, clinical-stage biotechnology company engaged in developing novel therapies for cancers, chronic hepatitis B (CHB), and age-related diseases, today announced its appointment of Dr. David Sidransky, MD., a renowned oncologist, to the company's Board of Directors as an independent non-executive director, effective on March 31, 2021. Known for in research in biomarkers for early detection and therapy and profiled by TIME magazine in 2001 as one of America's best in science and medicine, Dr. Sidransky is a leading expert in oncology and precision medicine widely respected in the biophar

      4/2/21 7:33:00 AM ET
      $ADXS
      Major Pharmaceuticals
      Health Care

    $ADXS
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • SEC Form SC 13G/A filed by Advaxis, Inc. (Amendment)

      SC 13G/A - Ayala Pharmaceuticals, Inc. (0001100397) (Subject)

      2/14/24 4:26:22 PM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • SEC Form SC 13D/A filed by Advaxis, Inc. (Amendment)

      SC 13D/A - Ayala Pharmaceuticals, Inc. (0001100397) (Subject)

      2/12/24 11:58:05 AM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • SEC Form SC 13G/A filed by Advaxis, Inc. (Amendment)

      SC 13G/A - Ayala Pharmaceuticals, Inc. (0001100397) (Subject)

      2/12/24 8:27:51 AM ET
      $ADXS
      Major Pharmaceuticals
      Health Care

    $ADXS
    Insider Purchases

    Insider purchases reveal critical bullish sentiment about the company from key stakeholders. See them live in this feed.

    See more

    $ADXS
    Financials

    Live finance-specific insights

    See more
    • Israel Biotech Fund I, L.P. bought 1,317,716 shares (SEC Form 4)

      4 - Ayala Pharmaceuticals, Inc. (0001100397) (Issuer)

      10/31/23 7:08:02 AM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • Updated RINGSIDE Phase 2 Results Featured in Poster Discussion Session at 2023 American Society of Clinical Oncology (ASCO) Annual Meeting

      Data show enhanced anti-tumor activity of AL102 over time Registration-enabling Phase 3 segment of RINGSIDE is enrolling patients globally Company to host conference call and webcast to discuss updated Phase 2 results on Wednesday, June 7 REHOVOT, Israel and MONMOUTH JUNCTION, N.J., June 05, 2023 (GLOBE NEWSWIRE) -- Ayala Pharmaceuticals, Inc. (OTCQX:ADXS), a clinical-stage oncology company, today announced further results from the Phase 2 (Part A) segment of the RINGSIDE study evaluating AL102 in desmoid tumors. The results were presented in a Poster Discussion Session at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting on Saturday, June 3. AL102 is a once-daily, po

      6/5/23 8:00:00 AM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • Ayala Pharmaceuticals Reports Financial Results For the Fiscal Year Ended October 31, 2022

      REHOVOT, Israel and MONMOUTH JUNCTION, N.J., Feb. 10, 2023 (GLOBE NEWSWIRE) -- Ayala Pharmaceuticals, Inc. (f/k/a Advaxis Inc.) (the "Company," "New Ayala," "we," "us" or "our") (OTCQX:ADXS), a clinical-stage oncology company, today announces financial results for the fiscal year ended October 31, 2022. Management Commentary "We were pleased to close our previously announced merger in January 2023," said Kenneth A. Berlin, President and Chief Executive Officer of the Company. "Our immediate priorities include executing on Part B of the ongoing registration-enabling RINGSIDE study evaluating AL102 in desmoid tumors. We believe that AL102 has best in class potential and, if approved, m

      2/10/23 7:00:31 AM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • Advaxis and Ayala Pharmaceuticals Enter into Merger Agreement

      Merger brings U.S. management and presence, cash to develop compelling late-stage asset Lead candidate AL102 being evaluated in ongoing Phase 2/3 RINGSIDE study, a potential registration trial in desmoid tumors Ayala and Advaxis stockholders will respectively own approximately 62.5% and 37.5% Combined Company to Seek Uplisting to Nasdaq Conference Call and Webcast today at 8:00am ET REHOVOT, Israel and WILMINGTON, Del. and MONMOUTH JUNCTION, N.J., Oct. 19, 2022 (GLOBE NEWSWIRE) -- Ayala Pharmaceuticals, Inc. (NASDAQ:AYLA) (Ayala), a clinical-stage oncology company focused on developing and commercializing small molecule therapeutics for patients suffering from rare tumors and aggressi

      10/19/22 6:30:00 AM ET
      $ADXS
      $AYLA
      Major Pharmaceuticals
      Health Care
      Specialty Chemicals
      Consumer Discretionary

    $ADXS
    SEC Filings

    See more
    • SEC Form 15-12G filed by Advaxis, Inc.

      15-12G - Ayala Pharmaceuticals, Inc. (0001100397) (Filer)

      5/9/24 4:05:37 PM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • SEC Form 10-K/A filed by Advaxis, Inc. (Amendment)

      10-K/A - Ayala Pharmaceuticals, Inc. (0001100397) (Filer)

      4/26/24 5:03:01 PM ET
      $ADXS
      Major Pharmaceuticals
      Health Care
    • Advaxis, Inc. filed SEC Form 8-K: Financial Statements and Exhibits (Amendment)

      8-K/A - Ayala Pharmaceuticals, Inc. (0001100397) (Filer)

      4/19/24 7:50:34 AM ET
      $ADXS
      Major Pharmaceuticals
      Health Care