• Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Quantisnow Logo
  • Live Feeds
    • Press Releases
    • Insider Trading
    • FDA Approvals
    • Analyst Ratings
    • Insider Trading
    • SEC filings
    • Market insights
  • Analyst Ratings
  • Alerts
  • Subscriptions
  • Settings
  • RSS Feeds
Dashboard
    Quantisnow Logo

    © 2025 quantisnow.com
    Democratizing insights since 2022

    Services
    Live news feedsRSS FeedsAlerts
    Company
    AboutQuantisnow PlusContactJobs
    Legal
    Terms of usePrivacy policyCookie policy

    SEC Form S-8 POS filed by Zynerba Pharmaceuticals Inc.

    10/11/23 9:27:00 AM ET
    $ZYNE
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ZYNE alert in real time by email
    S-8 POS 1 ny20011256x3-x12_s8pos.htm S-8 POS
    As filed with the Securities and Exchange Commission on October 11, 2023
    No. 333-272805
    No. 333-270891
    No. 333-263128
    No. 333-256028
    No. 333-237051
    No. 333-230182
    No. 333-223597
    No. 333-216967
    No. 333-216968
    No. 333-207973


    UNITED STATES
    SECURITIES AND EXCHANGE COMMISSION
    Washington, D.C. 20549



    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-272805
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-270891
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-263128
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-256028
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-237051
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-230182
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-223597
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-216967
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-216968
    Post-Effective Amendment No. 1 to FORM S-8 REGISTRATION STATEMENT No. 333-207973

    UNDER
    THE SECURITIES ACT OF 1933



    ZYNERBA PHARMACEUTICALS, INC.
    (Exact name of registrant as specified in its charter)



    Delaware
     
    26-0389433
    (State or other jurisdiction of
    incorporation or organization)
     
    (I.R.S. Employer
    Identification No.)

    80 W. Lancaster Avenue, Suite 300
    Devon, PA 19333
    (484) 581-7505
    (Address of registrant’s principal executive offices)



    Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan
    Zynerba Pharmaceuticals, Inc. 2023 Stock Option and Incentive Plan
    Non-Qualified Stock Option Inducement Award
    (Full titles of the plans)



    Christian Ulrich
    Secretary
    80 W. Lancaster Avenue, Suite 300
    Devon, Pennsylvania 19333
    (484) 581-7505
    (Name, address and telephone number of agent for service)

    Copy To:
    William Intner
    Hogan Lovells US LLP
    100 International Drive
    Baltimore, MD 21202
    (410) 659-2700

    and to:
    Peter Cohen-Millstein
    Hogan Lovells US LLP
    390 Madison Avenue
    New York, NY 10017
    (212) 918-3000



    Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

    Large accelerated filer
    ☐
     
    Accelerated filer
    ☐
    Non-accelerated filer
    ☒
     
    Smaller reporting company
    ☒
         
    Emerging growth company
    ☐

    If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ☐




    EXPLANATORY NOTE

    This Post-Effective Amendment No. 1 relates to the following Registration Statements of Zynerba Pharmaceuticals, Inc. (the “Company”) on Form S-8 (collectively, the “Registration Statements”):

     
    •
    Registration Statement No. 333-207973, registering 1,854,161 shares of common stock of the Company, par value $0.001 per share (“Shares”), issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan., filed with the Securities and Exchange Commission (the “Commission”) on November 13, 2015;
         
     
    •
    Registration Statement No. 333-216967, registering 150,000 Shares, issuable pursuant to the Company’s Non-Qualified Stock Option Inducement Award, filed with the Commission on March 27, 2017;
         
     
    •
    Registration Statement No. 333-216968, registering 999,482 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 27, 2017;
         
     
    •
    Registration Statement No. 333-223597, registering 1,355,387 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 12, 2018;
         
     
    •
    Registration Statement No. 333-230182, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 11, 2019;
         
     
    •
    Registration Statement No. 333-237051, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 10, 2020;
         
     
    •
    Registration Statement No. 333-256028, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on May 12, 2021;
         
     
    •
    Registration Statement No. 333-263128, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 1, 2022;
         
     
    •
    Registration Statement No. 333-270891, registering 1,500,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. Amended and Restated 2014 Omnibus Incentive Compensation Plan, filed with the Commission on March 28, 2023; and
         
     
    •
    Registration Statement No. 333-272805, registering 6,900,000 Shares, issuable pursuant to the Zynerba Pharmaceuticals, Inc. 2023 Stock Option and Incentive Plan, filed with the Commission on June 21, 2023.

    On August 14, 2023, the Company entered into an Agreement and Plan of Merger (the “Merger Agreement”) with Harmony Biosciences Holdings, Inc., a Delaware corporation (“Parent”) and Xylophone Acquisition Corp., a Delaware corporation and a wholly owned subsidiary of Parent (“Purchaser”). Pursuant to the Merger Agreement, on October 10, 2023, Purchaser merged with and into the Company (the “Merger”), with the Company surviving the Merger as a wholly owned subsidiary of Parent.

    In connection with the Merger, the offerings of securities pursuant to the Registration Statements have been terminated. In accordance with the undertakings made by the Company in the Registration Statements to remove from registration, by means of a post-effective amendment, any of the securities registered pursuant to the Registration Statements which remain unsold at the termination of the offerings, the Company hereby terminates the effectiveness of each Registration Statement and removes from registration all Shares registered under the Registration Statements that remain unsold as of the date hereof. Each Registration Statement is hereby amended, as appropriate, to reflect the deregistration of such securities. After giving effect to this Post-Effective Amendment No. 1 to the Registration Statements, there will be no remaining securities registered by the Company pursuant to the Registration Statements.



    SIGNATURES

    Pursuant to the requirements of the Securities Act of 1933, as amended, the Company certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Post-Effective Amendment No. 1 to the Registration Statements on Form S-8 to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Devon, Commonwealth of Pennsylvania, on October 11, 2023.

     
    ZYNERBA PHARMACEUTICALS, INC.
         
     
    By:
    /s/ Sandip Kapadia
     
    Name:
    Sandip Kapadia
     
    Title:
    President, Chief Executive Officer and Chief Financial Officer


    No other person is required to sign this Post-Effective Amendment No. 1 to the Registration Statements in reliance upon Rule 478 under the Securities Act of 1933, as amended.


    Get the next $ZYNE alert in real time by email

    Chat with this insight

    Save time and jump to the most important pieces.

    Recent Analyst Ratings for
    $ZYNE

    DatePrice TargetRatingAnalyst
    More analyst ratings

    $ZYNE
    Press Releases

    Fastest customizable press release news feed in the world

    See more
    • HARMONY BIOSCIENCES COMPLETES ACQUISITION OF ZYNERBA PHARMACEUTICALS AND EXPANDS PIPELINE

      New product in development diversifies portfolio to drive long-term growth  Innovative potential new therapeutic option for rare/orphan neuropsychiatric disorders with high unmet medical needs Zygel™ in pivotal Phase 3 trial for Fragile X syndrome and has completed Phase 2 proof-of-concept study in 22q11.2 deletion syndrome PLYMOUTH MEETING, Pa., Oct. 11, 2023 /PRNewswire/ -- Harmony Biosciences Holdings, Inc. ("Harmony") (NASDAQ:HRMY), a pharmaceutical company dedicated to developing and commercializing innovative therapies for patients with rare neurological diseases, today announced that it has completed its acquisition of Zynerba Pharmaceuticals, Inc. ("Zynerba") (NASDAQ:ZYNE).

      10/11/23 8:00:00 AM ET
      $HRMY
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Important Information for Zynerba Pharmaceuticals Stockholders to Tender Shares for the Harmony Transaction: Process and Instructions

      DEVON, Pa., Oct. 04, 2023 (GLOBE NEWSWIRE) -- Zynerba Pharmaceuticals, Inc. (NASDAQ:ZYNE), the leader in innovative pharmaceutically-produced transdermal cannabinoid therapies for orphan neuropsychiatric disorders, today reminds all stockholders, including individual stockholders, to promptly tender their shares into the tender offer (the "Offer") by Harmony Biosciences Holdings, Inc. ("Harmony") and its wholly owned subsidiary, Xylophone Acquisition Corp. ("Purchaser"), to purchase all outstanding shares of Zynerba common stock. The Zynerba Board of Directors unanimously recommends that Zynerba stockholders tender their shares pursuant to the Offer. Key Information to Know Tender Deadl

      10/4/23 4:05:00 PM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Zynerba Pharmaceuticals Stockholders Reminded to Tender Shares Before 5:00 PM New York City Time, on Tuesday October 10, 2023

      DEVON, Pa., Sept. 29, 2023 (GLOBE NEWSWIRE) -- Zynerba Pharmaceuticals, Inc. (NASDAQ:ZYNE), the leader in innovative pharmaceutically-produced transdermal cannabinoid therapies for orphan neuropsychiatric disorders, today released the following letter to stockholders concerning the pending tender offer by Harmony Biosciences Holdings, Inc. ("Harmony"). Fellow Zynerba Pharmaceuticals Stockholders, We urge you to promptly tender your shares in response to the pending tender offer (the "Offer") by Harmony and its wholly owned subsidiary, Xylophone Acquisition Corp. ("Purchaser"). As previously disclosed, the Offer is to purchase all of the issued and outstanding shares of the co

      9/29/23 9:00:00 AM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ZYNE
    SEC Filings

    See more
    • SEC Form 15-12G filed by Zynerba Pharmaceuticals Inc.

      15-12G - Zynerba Pharmaceuticals, Inc. (0001621443) (Filer)

      10/19/23 4:48:36 PM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form EFFECT filed by Zynerba Pharmaceuticals Inc.

      EFFECT - Zynerba Pharmaceuticals, Inc. (0001621443) (Filer)

      10/12/23 12:15:05 AM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form POS AM filed by Zynerba Pharmaceuticals Inc.

      POS AM - Zynerba Pharmaceuticals, Inc. (0001621443) (Filer)

      10/11/23 9:27:41 AM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ZYNE
    Insider Trading

    Insider transactions reveal critical sentiment about the company from key stakeholders. See them live in this feed.

    See more
    • Jones Kenneth T was granted 30,000 shares, closing all direct ownership in the company (SEC Form 4)

      4 - Zynerba Pharmaceuticals, Inc. (0001621443) (Issuer)

      10/11/23 10:17:14 AM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Stephenson Pamela closing all direct ownership in the company (SEC Form 4)

      4 - Zynerba Pharmaceuticals, Inc. (0001621443) (Issuer)

      10/11/23 10:12:57 AM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Fickenscher James E was granted 170,000 shares, closing all direct ownership in the company (SEC Form 4)

      4 - Zynerba Pharmaceuticals, Inc. (0001621443) (Issuer)

      10/11/23 10:12:34 AM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ZYNE
    Large Ownership Changes

    This live feed shows all institutional transactions in real time.

    See more
    • SEC Form SC 13G/A filed by Zynerba Pharmaceuticals Inc. (Amendment)

      SC 13G/A - Zynerba Pharmaceuticals, Inc. (0001621443) (Subject)

      2/8/24 7:22:51 PM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G filed by Zynerba Pharmaceuticals Inc.

      SC 13G - Zynerba Pharmaceuticals, Inc. (0001621443) (Subject)

      9/5/23 4:39:51 PM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • SEC Form SC 13G/A filed by Zynerba Pharmaceuticals Inc. (Amendment)

      SC 13G/A - Zynerba Pharmaceuticals, Inc. (0001621443) (Subject)

      2/14/22 3:52:48 PM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ZYNE
    Leadership Updates

    Live Leadership Updates

    See more
    • Zynerba Pharmaceuticals Announces Planned Retirement of Suzanne Hanlon and Appoints Albert P. Parker as Chief Legal Officer

      DEVON, Pa., Feb. 15, 2022 (GLOBE NEWSWIRE) -- Zynerba Pharmaceuticals, Inc. (NASDAQ:ZYNE), the leader in innovative pharmaceutically-produced transdermal cannabinoid therapies for rare and near-rare neuropsychiatric disorders, today announced the appointment of Albert P. Parker, an accomplished industry executive with over 25 years of pharmaceutical, biotech and healthcare experience, as Chief Legal Officer and Corporate Secretary. He will assume the duties of Suzanne Hanlon who will retire from her position at the end of February 2022. "We are excited to have Al join our senior leadership team. He is an experienced legal and business executive who brings significant strategic and hands-o

      2/15/22 7:00:00 AM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Immunome Provides Organizational Update: Appoints Richard Baron to its Board of Directors and Sandra Stoneman as Chief Legal Officer and Corporate Secretary

      EXTON, Pa.--(BUSINESS WIRE)--Immunome, Inc. (Nasdaq: IMNM), a biopharmaceutical company utilizing a proprietary human memory B cell platform to discover and develop first-in-class antibody therapeutics, with a focus on oncology and infectious diseases including COVID-19, today announced the recent appointments of Richard Baron to Immunome’s Board of Directors and as Audit Committee Chair, and Sandra Stoneman, Esq. as Chief Legal Officer and Corporate Secretary. The company also today announced that its President and Chief Executive Officer, Purnanand Sarma, Ph.D. is the recipient of TiE Boston’s 2020 Lifetime Achievement Award. The award recognizes individuals who have made invaluab

      12/10/20 8:00:00 AM ET
      $GMED
      $PUMP
      $ZYNE
      Medical/Dental Instruments
      Health Care
      Oilfield Services/Equipment
      Energy

    $ZYNE
    Analyst Ratings

    Analyst ratings in real time. Analyst ratings have a very high impact on the underlying stock. See them live in this feed.

    See more
    • Roth Capital reiterated coverage on Zynerba Pharmaceuticals with a new price target

      Roth Capital reiterated coverage of Zynerba Pharmaceuticals with a rating of Buy and set a new price target of $7.25 from $8.00 previously

      3/10/21 4:21:24 PM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Canaccord Genuity resumed coverage on Zynerba Pharmaceuticals with a new price target

      Canaccord Genuity resumed coverage of Zynerba Pharmaceuticals with a rating of Buy and set a new price target of $18.00

      2/5/21 4:18:35 AM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care

    $ZYNE
    Financials

    Live finance-specific insights

    See more
    • HARMONY BIOSCIENCES COMPLETES ACQUISITION OF ZYNERBA PHARMACEUTICALS AND EXPANDS PIPELINE

      New product in development diversifies portfolio to drive long-term growth  Innovative potential new therapeutic option for rare/orphan neuropsychiatric disorders with high unmet medical needs Zygel™ in pivotal Phase 3 trial for Fragile X syndrome and has completed Phase 2 proof-of-concept study in 22q11.2 deletion syndrome PLYMOUTH MEETING, Pa., Oct. 11, 2023 /PRNewswire/ -- Harmony Biosciences Holdings, Inc. ("Harmony") (NASDAQ:HRMY), a pharmaceutical company dedicated to developing and commercializing innovative therapies for patients with rare neurological diseases, today announced that it has completed its acquisition of Zynerba Pharmaceuticals, Inc. ("Zynerba") (NASDAQ:ZYNE).

      10/11/23 8:00:00 AM ET
      $HRMY
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • HARMONY BIOSCIENCES TO ACQUIRE ZYNERBA PHARMACEUTICALS, INC.

      PLYMOUTH MEETING, Pa. and DEVON, Pa., Aug. 14, 2023 /PRNewswire/ -- Harmony Biosciences Holdings, Inc. ("Harmony") (NASDAQ:HRMY), a pharmaceutical company dedicated to developing and commercializing innovative therapies for patients with rare neurological diseases, today announced a definitive agreement to acquire Zynerba Pharmaceuticals, Inc. ("Zynerba") (NASDAQ:ZYNE), a leader in innovative pharmaceutically-produced transdermal cannabinoid therapies for orphan neuropsychiatric disorders, including Fragile X syndrome (FXS). Under the terms of the definitive agreement, Harmony

      8/14/23 7:30:00 AM ET
      $HRMY
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care
    • Zynerba Pharmaceuticals Announces Positive Top Line Results from Open-Label Phase 2 INSPIRE Trial of Zygel™ in 22q11.2 Deletion Syndrome

      – The INSPIRE trial achieved statistically significant and clinically meaningful improvements from baseline in multiple efficacy assessments – – Safety data reinforce excellent tolerability profile of Zygel – – Company will focus resources on FXS and 22q development – – Cash runway extended through the end of 2023 / early 2024 – – Zynerba to host conference call and webcast tomorrow, June 22, 2022 at 9:00 a.m. ET – DEVON, Pa., June 21, 2022 (GLOBE NEWSWIRE) -- Zynerba Pharmaceuticals, Inc. (NASDAQ:ZYNE), the leader in innovative pharmaceutically-produced transdermal cannabinoid therapies for orphan neuropsychiatric disorders, today announced positive top line results from the explorat

      6/21/22 8:05:00 PM ET
      $ZYNE
      Biotechnology: Pharmaceutical Preparations
      Health Care