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    SEC Form SC 13D/A filed by ADC Therapeutics SA (Amendment)

    4/28/23 4:08:00 PM ET
    $ADCT
    Biotechnology: Pharmaceutical Preparations
    Health Care
    Get the next $ADCT alert in real time by email
    SC 13D/A 1 d466545dsc13da.htm SC 13D/A SC 13D/A

     

     

    UNITED STATES

    SECURITIES AND EXCHANGE COMMISSION

    WASHINGTON, D.C. 20549

     

     

    SCHEDULE 13D

    UNDER THE SECURITIES EXCHANGE ACT OF 1934

    (Amendment No. 6)*

     

     

    ADC Therapeutics SA

    (Name of Issuer)

    Common Shares, par value CHF 0.08 per share

    (Title and Class of Securities)

    H0036K147

    (CUSIP Number)

    Stephen Evans-Freke

    Auven Therapeutics Holdings L.P.

    171 Main Street

    Road Town

    Tortola

    British Virgin Islands VG1110

    (340) 779-6908

    (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

    April 27, 2023

    (Date of Event Which Requires Filing of Statement)

     

     

     

    If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), Rule 13d-1(f) or Rule 13d-1(g), check the following box. ☐

     

     

    Note. Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7(b) for other parties to whom copies are to be sent.

     

     

    *

    The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

    The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes)

     

     

     


    Schedule 13D

    CUSIP No. H0036K147

     

      1    

      NAME OF REPORTING PERSON

     

      A.T. Holdings II Sarl

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      SOURCE OF FUNDS

     

      WC

      5  

      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

      ☐

      6  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      Switzerland

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH:

     

         7    

      SOLE VOTING POWER

     

      0

         8  

      SHARED VOTING POWER

     

      6,330,548

         9  

      SOLE DISPOSITIVE POWER

     

      0

       10  

      SHARED DISPOSITIVE POWER

     

      6,330,548

    11    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

     

      6,330,548

    12  

      CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

      ☐

    13  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

      7.9% (1)

    14  

      TYPE OF REPORTING PERSON

     

      OO

     

    (1)

    Based on 80,642,527 common shares of ADC Therapeutics SA (the “Issuer”) outstanding as of December 31, 2022, as reported in the Issuer’s Form 20-F filed with the Securities and Exchange Commission (“SEC”) on March 15, 2023.


    Schedule 13D

    CUSIP No. H0036K147

     

      1    

      NAME OF REPORTING PERSON

     

      C.T. Phinco Sarl

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      SOURCE OF FUNDS

     

      AF

      5  

      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

      ☐

      6  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      Luxembourg

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH:

     

         7    

      SOLE VOTING POWER

     

      6,330,548

         8  

      SHARED VOTING POWER

     

      0

         9  

      SOLE DISPOSITIVE POWER

     

      6,330,548

       10  

      SHARED DISPOSITIVE POWER

     

      0

    11    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

     

      6,330,548

    12  

      CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

      ☐

    13  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

      7.9% (1)

    14  

      TYPE OF REPORTING PERSON

     

      OO

     

    (1)

    Based on 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as reported in the Issuer’s Form 20-F filed with the SEC on March 15, 2023.


    Schedule 13D

    CUSIP No. H0036K147

     

      1    

      NAME OF REPORTING PERSON

     

      ADC Products Switzerland Sarl

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      SOURCE OF FUNDS

     

      WC

      5  

      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

      ☐

      6  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      Switzerland

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH:

     

         7    

      SOLE VOTING POWER

     

      0

         8  

      SHARED VOTING POWER

     

      2,228,085

         9  

      SOLE DISPOSITIVE POWER

     

      0

       10  

      SHARED DISPOSITIVE POWER

     

      2,228,085

    11    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

     

      2,228,085

    12  

      CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

      ☐

    13  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

      2.8% (1)

    14  

      TYPE OF REPORTING PERSON

     

      OO

     

    (1)

    Based on 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as reported in the Issuer’s Form 20-F filed with the SEC on March 15, 2023.


    Schedule 13D

    CUSIP No. H0036K147

     

      1    

      NAME OF REPORTING PERSON

     

      Auven Therapeutics Holdings L.P.

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      SOURCE OF FUNDS

     

      AF

      5  

      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

      ☐

      6  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      British Virgin Islands

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH:

     

         7    

      SOLE VOTING POWER

     

      0

         8  

      SHARED VOTING POWER

     

      6,330,548

         9  

      SOLE DISPOSITIVE POWER

     

      0

       10  

      SHARED DISPOSITIVE POWER

     

      6,330,548

    11    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

     

      6,330,548

    12  

      CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

      ☐

    13  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

      7.9% (1)

    14  

      TYPE OF REPORTING PERSON

     

      PN

     

    (1)

    Based on 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as reported in the Issuer’s Form 20-F filed with the SEC on March 15, 2023.


    Schedule 13D

    CUSIP No. H0036K147

     

      1    

      NAME OF REPORTING PERSON

     

      Auven Therapeutics General L.P.

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      SOURCE OF FUNDS

     

      AF

      5  

      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

      ☐

      6  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      British Virgin Islands

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH:

     

         7    

      SOLE VOTING POWER

     

      0

         8  

      SHARED VOTING POWER

     

      6,330,548

         9  

      SOLE DISPOSITIVE POWER

     

      0

       10  

      SHARED DISPOSITIVE POWER

     

      6,330,548

    11    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

     

      6,330,548

    12  

      CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

      ☐

    13  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

      7.9% (1)

    14  

      TYPE OF REPORTING PERSON

     

      PN

     

    (1)

    Based on 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as reported in the Issuer’s Form 20-F filed with the SEC on March 15, 2023.


    Schedule 13D

    CUSIP No. H0036K147

     

      1    

      NAME OF REPORTING PERSON

     

      Auven Therapeutics GP Ltd.

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      SOURCE OF FUNDS

     

      AF

      5  

      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

      ☐

      6  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      British Virgin Islands

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH:

     

         7    

      SOLE VOTING POWER

     

      0

         8  

      SHARED VOTING POWER

     

      6,330,548

         9  

      SOLE DISPOSITIVE POWER

     

      0

       10  

      SHARED DISPOSITIVE POWER

     

      6,330,548

    11    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

     

      6,330,548

    12  

      CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

      ☐

    13  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

      7.9% (1)

    14  

      TYPE OF REPORTING PERSON

     

      CO

     

    (1)

    Based on 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as reported in the Issuer’s Form 20-F filed with the SEC on March 15, 2023.


    Schedule 13D

    CUSIP No. H0036K147

     

      1    

      NAME OF REPORTING PERSON

     

      Stephen Evans-Freke

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      SOURCE OF FUNDS

     

      AF

      5  

      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

      ☐

      6  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      Ireland

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH:

     

         7    

      SOLE VOTING POWER

     

      0

         8  

      SHARED VOTING POWER

     

      6,330,548

         9  

      SOLE DISPOSITIVE POWER

     

      0

       10  

      SHARED DISPOSITIVE POWER

     

      6,330,548

    11    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

     

      6,330,548

    12  

      CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

      ☐

    13  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

      7.9% (1)

    14  

      TYPE OF REPORTING PERSON

     

      IN

     

    (1)

    Based on 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as reported in the Issuer’s Form 20-F filed with the SEC on March 15, 2023.


    Schedule 13D

    CUSIP No. H0036K147

     

      1    

      NAME OF REPORTING PERSON

     

      Peter B. Corr

      2  

      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

      (a)  ☐        (b)  ☐

     

      3  

      SEC USE ONLY

     

      4  

      SOURCE OF FUNDS

     

      AF

      5  

      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)

     

      ☐

      6  

      CITIZENSHIP OR PLACE OF ORGANIZATION

     

      USA

    NUMBER OF

    SHARES

     BENEFICIALLY 

    OWNED BY

    EACH

    REPORTING

    PERSON

    WITH:

     

         7    

      SOLE VOTING POWER

     

      0

         8  

      SHARED VOTING POWER

     

      6,330,548

         9  

      SOLE DISPOSITIVE POWER

     

      0

       10  

      SHARED DISPOSITIVE POWER

     

      6,330,548

    11    

      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

     

      6,330,548

    12  

      CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES

     

      ☐

    13  

      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

     

      7.9% (1)

    14  

      TYPE OF REPORTING PERSON

     

      IN

     

    (1)

    Based on 80,642,527 common shares of the Issuer outstanding as of December 31, 2022, as reported in the Issuer’s Form 20-F filed with the SEC on March 15, 2023.


    AMENDMENT NO. 6 TO SCHEDULE 13D

    The following constitutes Amendment No. 6 (“Amendment No. 6”) to the Schedule 13D filed with the Securities and Exchange Commission (“SEC”) by A.T. Holdings II Sàrl (“A.T. Holdings II”), C.T. Phinco Sàrl (“C.T. Phinco”), ADC Products Switzerland Sàrl (“ADC Products”), Auven Therapeutics Holdings L.P. (“Auven Therapeutics”), Auven Therapeutics General L.P. (“Auven Therapeutics General”), Auven Therapeutics GP Ltd. (“Auven Therapeutics GP”), Stephen Evans-Freke and Peter B. Corr (collectively, the “Reporting Persons”) on May 29, 2020, as amended by Amendment No. 1 filed on October 13, 2020, Amendment No. 2 filed on December 8, 2022, Amendment No. 3 filed on December 9, 2022, Amendment No. 4 filed on December 23, 2022, and Amendment No. 5 filed on February 6, 2023. This Amendment No. 6 amends and supplements the Schedule 13D as specifically set forth herein.

    All capitalized terms contained herein but not otherwise defined shall have the meanings ascribed to such terms in the Schedule 13D, as amended. Information given in response to each item shall be deemed incorporated by reference in all other items, as applicable.

     

    ITEM 4.

    PURPOSE OF TRANSACTION

    Item 4 of Schedule 13D is supplemented and superseded, as the case may be, as follows:

    The disclosure in Item 6 is incorporated herein by reference.

     

    ITEM 6.

    CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR RELATIONSHIPS WITH RESPECT TO SECURITIES OF THE ISSUER

    Item 6 of Schedule 13D is supplemented and superseded, as the case may be, as follows:

    Sixth Amendment to Credit and Security Agreement

    As previously disclosed, A.T. Holdings II is a borrower under the Credit and Security Agreement and has pledged to the lenders party thereto all of the Common Shares beneficially owned by it or afterward acquired by it to secure the lending by such lenders to A.T. Holdings II pursuant to the Credit and Security Agreement. On April 27, 2023, A.T. Holdings II, as Borrower, C.T. Phinco, as Holdings, the Agent, and the lenders party thereto entered into a Sixth Amendment to the Credit and Security Agreement (the “Sixth Amendment”).

    The Sixth Amendment, among other things, provides that C.T. Phinco joins the Credit and Security Agreement as a guarantor and pledges its shares of A.T. Holdings II to secure the Credit and Security Agreement. Furthermore, the Sixth Amendment (i) extends the maturity date to April 15, 2024, (ii) sets the interest rate at (a) 20.00% per annum from February 6, 2023 through September 30, 2023 and (b) 22.5% per annum on and after October 1, 2023, (iii) provides that scheduled interest shall be payable in kind, and (iv) requires that, subject to certain exceptions, cash proceeds from the sale of equity interests be used to repay the obligations under the Credit and Security Agreement. Following A.T. Holdings’ partial repayment of its obligations under the Credit and Security Agreement using proceeds from the Registered Sale, the outstanding principal balance owed under the Credit and Security Agreement was $18,679,772.44 as of the effective date of the Sixth Amendment. The effectiveness of the Sixth Amendment was dependent on the simultaneous execution of the Share Transfer Agreement (as defined below).


    Share Transfer Agreement

    On April 27, 2023, A.T. Holdings II entered into a Share Transfer Agreement (the “Share Transfer Agreement”) with each lender party thereto (collectively, the “Lenders”) and Oaktree Fund Administration, LLC, as administrative agent on behalf of the lenders (the “Agent”). Pursuant to the Share Transfer Agreement, as soon as reasonably practicable after the payment in full of all obligations under the Credit and Security Agreement, and in any event within five business days following such payment, A.T. Holdings II shall irrevocably transfer, convey, assign and deliver an aggregate of 1,435,749 Common Shares (the “ADCT Shares”) of the Issuer, free and clear of all liens, to the Lenders, which ADCT Shares shall be allocated among the Lenders pro rata in accordance with the principal amount of credit extensions outstanding under the Credit and Security Agreement. The Share Transfer Agreement provides that notwithstanding the foregoing, if, at the earlier of (i) the maturity date of the Credit and Security Agreement or (ii) the acceleration of the obligations under the Credit and Security Agreement, (a) the Agent determines in its sole discretion that A.T. Holdings II does not have sufficient monetizable assets (other than the ADCT Shares) to repay in full all obligations under the Credit and Security Agreement and (b) A.T. Holdings II and the Lenders agree on compensation to the Lenders for allowing the sale of the ADCT Shares, then, following the sale of all other shares of the Issuer that constitute collateral under the Credit and Security Agreement and upon such determination, A.T. Holdings II shall have the right to sell all or a portion of the ADCT Shares and use the proceeds from such sale to pay in full all obligations under the Credit and Security Agreement; provided that any excess cash from such sales is the property of the Lenders.

    The foregoing description of the Share Transfer Agreement does not purport to be complete and is qualified in its entirety by reference to the full text of the Share Transfer Agreement, which is filed as Exhibit 99.1 and is incorporated herein by reference.

     

    ITEM 7.

    MATERIAL TO BE FILED AS EXHIBITS

     

    Exhibit    Description
    99.1    Share Transfer Agreement, dated April 27, 2023, by and between A.T. Holdings II Sàrl, each lender party thereto, and Oaktree Fund Administration, LLC, as administrative agent on behalf of the lenders.


    SIGNATURE

    After reasonable inquiry and to the best of my knowledge and belief, each of the undersigned certifies that the information set forth in this statement is true, complete and correct.

    Dated as of April 28, 2023

     

    A.T. HOLDINGS II SÁRL
    By:  

    /s/ Stephen Evans-Freke

    Name:   Stephen Evans-Freke
    Title:   Managing Director
    By:  

    /s/ Peter B. Corr

    Name:   Peter B. Corr
    Title:   Managing Director
    C.T. PHINCO SÁRL
    By:  

    /s/ Stephen Evans-Freke

    Name:   Stephen Evans-Freke
    Title:   Class A Manager
    By:  

    /s/ Luis Tavares

    Name:   Luis Tavares
    Title:   Class B Manager
    ADC PRODUCTS SWITZERLAND SÁRL
    By:  

    /s/ Stephen Evans-Freke

    Name:   Stephen Evans-Freke
    Title:   Managing Director
    By:  

    /s/ Peter B. Corr

    Name:   Peter B. Corr
    Title:   Managing Director
    AUVEN THERAPEUTICS HOLDINGS L.P.
    By:   Auven Therapeutics General L.P., its general partner

    By:

     

    Auven Therapeutics GP Ltd., its general partner

    By:  

    /s/ Stephen Evans-Freke

    Name:   Stephen Evans-Freke
    Title:   Director


    AUVEN THERAPEUTICS GENERAL L.P.
    By:   Auven Therapeutics GP Ltd., its general partner
    By:  

    /s/ Stephen Evans-Freke

    Name:   Stephen Evans-Freke
    Title:   Director
    AUVEN THERAPEUTICS GP LTD.
    By:  

    /s/ Stephen Evans-Freke

    Name:   Stephen Evans-Freke
    Title:   Director
    By:  

    /s/ Stephen Evans-Freke

    By:  

    /s/ Peter B. Corr

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    9/21/2022$5.00Overweight
    JP Morgan
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    Insider Purchases

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    • Large owner Redmile Group, Llc bought $609,000 worth of shares (200,000 units at $3.04) (SEC Form 4)

      4 - ADC Therapeutics SA (0001771910) (Issuer)

      12/13/24 9:00:14 PM ET
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    • Large owner Redmile Group, Llc bought $2,248,000 worth of shares (800,000 units at $2.81) (SEC Form 4)

      4 - ADC Therapeutics SA (0001771910) (Issuer)

      7/3/24 8:00:13 PM ET
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    Insider Trading

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    • Large owner Wild Hans Peter acquired 9,788,944 shares (SEC Form 4)

      4 - ADC Therapeutics SA (0001771910) (Issuer)

      5/19/25 3:52:01 PM ET
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    • See Explanations Pfisterer Thomas disposed of 451,856 shares, decreasing direct ownership by 72% to 173,899 units (SEC Form 4)

      4 - ADC Therapeutics SA (0001771910) (Issuer)

      5/19/25 3:35:33 PM ET
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    • Chief Executive Officer Mallik Ameet covered exercise/tax liability with 26,758 shares, decreasing direct ownership by 2% to 1,552,247 units (SEC Form 4)

      4 - ADC Therapeutics SA (0001771910) (Issuer)

      5/8/25 9:14:46 PM ET
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    Financials

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    • ADC Therapeutics Reports First Quarter 2025 Financial Results and Provides Operational Update

      LOTIS-7 abstract accepted for presentation at the European Hematology Association 2025 Congress (EHA2025) and the 18th International Conference on Malignant Lymphoma (ICML); ZYNLONTA® plus glofitamab demonstrated ORR of 95.5% and CR of 90.9% with encouraging safety and tolerability Forty patient enrollment reached in LOTIS-7 trial dose expansion arm in patients with relapsed/refractory DLBCL Cash runway expected to fund multiple catalysts into the second half of 2026 Company to host conference call today at 8:30 a.m. EDT LAUSANNE, Switzerland, May 14, 2025 /PRNewswire/ -- ADC Therapeutics SA (NYSE:ADCT), a commercial-stage global leader and pioneer in the field of antibody drug conjugates (

      5/14/25 8:00:00 AM ET
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      Biotechnology: Pharmaceutical Preparations
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    • ADC Therapeutics to Host First Quarter 2025 Financial Results Conference Call on May 14, 2025

      LAUSANNE, Switzerland, May 8, 2025 /PRNewswire/ -- ADC Therapeutics SA (NYSE:ADCT), a commercial-stage global leader and pioneer in the field of antibody drug conjugates (ADCs), today announced that it will host a conference call and live webcast on Wednesday, May 14, 2025, at 8:30 a.m. EDT to report financial results for the first quarter 2025 and provide operational updates. To access the conference call, please register here. The participant toll-free dial-in number is 1-800-836-8184 for North America and Canada. It is recommended that you join 10 minutes before the event,

      5/8/25 7:15:00 AM ET
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    • ADC Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Operational Update

      Initial data from LOTIS-7 Phase 1b trial of ZYNLONTA® plus glofitamab demonstrated clinically meaningful benefit with 94% best ORR and 72% CR rate; data update expected in second quarter 2025 Completed enrollment in LOTIS-5 Phase 3 confirmatory trial of ZYNLONTA plus rituximab in patients with 2L+ DLBCL; data update anticipated in late 2025 once PFS events reached $250.9M in cash as of December 31, 2024, provides runway expected to fund operations into the second half of 2026 Company to host conference call today at 8:30 a.m. EDT LAUSANNE, Switzerland, March 27, 2025 /PRNewswire/ -- ADC Therapeutics SA (NYSE:ADCT), a commercial-stage global leader and pioneer in the field of antibody drug c

      3/27/25 7:30:00 AM ET
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    SEC Filings

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    • SEC Form 10-Q filed by ADC Therapeutics SA

      10-Q - ADC Therapeutics SA (0001771910) (Filer)

      5/14/25 4:07:39 PM ET
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    • ADC Therapeutics SA filed SEC Form 8-K: Results of Operations and Financial Condition, Financial Statements and Exhibits

      8-K - ADC Therapeutics SA (0001771910) (Filer)

      5/14/25 8:14:42 AM ET
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    • SEC Form DEF 14A filed by ADC Therapeutics SA

      DEF 14A - ADC Therapeutics SA (0001771910) (Filer)

      4/21/25 9:20:30 AM ET
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    FDA approvals

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    • FDA Approval for ZYNLONTA issued to ADC Therapeutics SA

      Submission status for ADC Therapeutics SA's drug ZYNLONTA (SUPPL-5) with active ingredient LONCASTUXIMAB TESIRINE-LPYL has changed to 'Approval' on 10/12/2022. Application Category: BLA, Application Number: 761196, Application Classification:

      10/13/22 1:04:01 PM ET
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    • FDA Approval for ZYNLONTA issued to ADC Therapeutics SA

      Submission status for ADC Therapeutics SA's drug ZYNLONTA (SUPPL-4) with active ingredient LONCASTUXIMAB TESIRINE-LPYL has changed to 'Approval' on 10/12/2022. Application Category: BLA, Application Number: 761196, Application Classification:

      10/13/22 1:03:14 PM ET
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    • FDA Approval for ZYNLONTA issued to ADC Therapeutics SA

      Submission status for ADC Therapeutics SA's drug ZYNLONTA (ORIG-1) with active ingredient LONCASTUXIMAB TESIRINE-LPYL has changed to 'Approval' on 04/23/2021. Application Category: BLA, Application Number: 761196, Application Classification:

      4/23/21 1:46:03 PM ET
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    • ADC Therapeutics to Present at Upcoming Investor Conferences

      LAUSANNE, Switzerland, May 15, 2025 /PRNewswire/ -- ADC Therapeutics SA (NYSE:ADCT), a commercial-stage global leader and pioneer in the field of antibody drug conjugates (ADCs), today announced participation in two upcoming investor conferences: RBC Capital Markets Global Healthcare ConferenceDate: May 21, 2025Presentation Time: 10:30-10:55 a.m. ETFormat: Fireside ChatSpeaker: Ameet Mallik, Chief Executive OfficerTo register for the webcast, click here. Jefferies Global Healthcare ConferenceDate: June 5, 2025Presentation Time: 9:55-10:25 a.m. ETFormat: Fireside ChatSpeaker: A

      5/15/25 7:15:00 AM ET
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      Biotechnology: Pharmaceutical Preparations
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    • ADC Therapeutics Reports First Quarter 2025 Financial Results and Provides Operational Update

      LOTIS-7 abstract accepted for presentation at the European Hematology Association 2025 Congress (EHA2025) and the 18th International Conference on Malignant Lymphoma (ICML); ZYNLONTA® plus glofitamab demonstrated ORR of 95.5% and CR of 90.9% with encouraging safety and tolerability Forty patient enrollment reached in LOTIS-7 trial dose expansion arm in patients with relapsed/refractory DLBCL Cash runway expected to fund multiple catalysts into the second half of 2026 Company to host conference call today at 8:30 a.m. EDT LAUSANNE, Switzerland, May 14, 2025 /PRNewswire/ -- ADC Therapeutics SA (NYSE:ADCT), a commercial-stage global leader and pioneer in the field of antibody drug conjugates (

      5/14/25 8:00:00 AM ET
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      Biotechnology: Pharmaceutical Preparations
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    • ADC Therapeutics Announces Presentation of LOTIS-7 Clinical Trial Data at the European Hematology Association 2025 Congress (EHA2025) and the 18th International Conference on Malignant Lymphoma (ICML)

      ZYNLONTA® plus glofitamab (COLUMVI®) demonstrated ORR of 95.5% and CR of 90.9%, among 22 evaluable patients with relapsed/refractory DLBCL Safety and tolerability data were consistent with the known profiles of each agent Updated data to be shared during poster presentation at EHA2025 on Saturday, June 14 at 12:30 p.m. ET and oral presentation at ICML on Friday, June 20 at 9:00 a.m. ET LAUSANNE, Switzerland, May 14, 2025 /PRNewswire/ -- ADC Therapeutics SA (NYSE:ADCT), a commercial-stage global leader and pioneer in the field of antibody drug conjugates (ADCs), today announced data presentations from the LOTIS-7 Phase 1b clinical trial evaluating ZYNLONTA (loncastuximab tesirine-lpyl) in com

      5/14/25 7:45:00 AM ET
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    Large Ownership Changes

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    • Myricx Bio Announces £90m ($114m) Series A Financing to Advance its Novel NMTi-ADC Therapeutics into Clinical Development

      £90m ($114m) series A co-led by new leading life science investors Novo Holdings and AbingworthAdditional new investors British Patient Capital, Cancer Research Horizons and Lilly participated alongside founding investors Brandon Capital and Sofinnova PartnersFunds will be used to build out Myricx Bio's proprietary N-Myristoyltransferase inhibitor (NMTi) antibody-drug conjugate (ADC) payload platform and advance its pipeline of NMTi-ADCs through clinical proof of concept targeting clinically validated tumour-associated antigensCompany to establish laboratory operations in London's biotech hub, and expand its management and R&D teamsMichael Bauer from Novo Holdings and Lucille Conroy from Abi

      7/8/24 2:00:00 AM ET
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    • ADC Therapeutics Set to Join Russell 2000® and Russell 3000® Indexes

      LAUSANNE, Switzerland, June 27, 2024 (GLOBE NEWSWIRE) -- ADC Therapeutics SA (NYSE:ADCT) today announced that the Company is set to join the Russell 2000® Index and the broad-market Russell 3000® Index at the conclusion of the 2024 Russell US Indexes annual reconstitution, effective at the open of US equity markets on Monday, July 1, 2024. "We are pleased to be joining the Russell 2000® Index," said Ameet Mallik, Chief Executive Officer of ADC Therapeutics. "This is a significant benchmark validating the focused execution of our corporate and capital allocation strategy and our progress toward multiple upcoming expected milestones throughout our hematology and solid tumor portfolios." Th

      6/27/24 7:15:00 AM ET
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    • Myricx Bio Appoints Dr Chris Martin, Biotech Entrepreneur and ADC Pioneer, as Chairman of its Board of Directors

      LONDON, Nov. 15, 2023 (GLOBE NEWSWIRE) -- Myricx Bio (‘Myricx'), a UK biotech company focused on the discovery and development of a completely novel class of antibody-drug conjugate (ADC) payloads based on N-Myristoyltransferase inhibition (NMTi), today announces the appointment of Dr Chris Martin as independent Chairman to its Board of Directors. Dr Martin is a renowned biotech company founder, director and entrepreneur, and a pioneer and leader in the ADC space. Dr Martin was instrumental in co-founding ADC Therapeutics (NYSE:ADCT) in Jan 2012 and served as its CEO since inception until May 2022. Under his leadership, ADC Therapeutics grew from a private biotech start-up to a New York

      11/15/23 3:00:00 AM ET
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    • Stephens initiated coverage on ADC Therapeutics with a new price target

      Stephens initiated coverage of ADC Therapeutics with a rating of Overweight and set a new price target of $6.00

      11/8/24 7:32:36 AM ET
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      Biotechnology: Pharmaceutical Preparations
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    • Cantor Fitzgerald initiated coverage on ADC Therapeutics

      Cantor Fitzgerald initiated coverage of ADC Therapeutics with a rating of Overweight

      5/30/24 7:26:04 AM ET
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      Biotechnology: Pharmaceutical Preparations
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    • Guggenheim initiated coverage on ADC Therapeutics with a new price target

      Guggenheim initiated coverage of ADC Therapeutics with a rating of Buy and set a new price target of $11.00

      3/28/24 7:31:32 AM ET
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    • Amendment: SEC Form SC 13G/A filed by ADC Therapeutics SA

      SC 13G/A - ADC Therapeutics SA (0001771910) (Subject)

      11/14/24 9:00:57 PM ET
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    • Amendment: SEC Form SC 13G/A filed by ADC Therapeutics SA

      SC 13G/A - ADC Therapeutics SA (0001771910) (Subject)

      11/13/24 8:58:56 AM ET
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    • Amendment: SEC Form SC 13G/A filed by ADC Therapeutics SA

      SC 13G/A - ADC Therapeutics SA (0001771910) (Subject)

      11/13/24 8:30:55 AM ET
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